-
1
-
-
43049156566
-
Human metabolic network reconstruction and its impact on drug discovery and development
-
10.1016/j.drudis.2008.02.002, 18468557
-
Ma H, Goryanin I. Human metabolic network reconstruction and its impact on drug discovery and development. Drug Discovery Today 2008, 13:402-408. 10.1016/j.drudis.2008.02.002, 18468557.
-
(2008)
Drug Discovery Today
, vol.13
, pp. 402-408
-
-
Ma, H.1
Goryanin, I.2
-
2
-
-
33749234216
-
Opinion - Drugs, their targets and the nature and number of drug targets
-
10.1038/nrd2132, 17016423
-
Imming P, Sinning C, Meyer A. Opinion - Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov 2006, 5:821-834. 10.1038/nrd2132, 17016423.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 821-834
-
-
Imming, P.1
Sinning, C.2
Meyer, A.3
-
3
-
-
33751547539
-
How many drug targets are there?
-
10.1038/nrd2199, 17139284
-
Overington JP, Al-Lazikani B, Hopkins AL. How many drug targets are there?. Nat Rev Drug Discov 2006, 5:993-996. 10.1038/nrd2199, 17139284.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 993-996
-
-
Overington, J.P.1
Al-Lazikani, B.2
Hopkins, A.L.3
-
4
-
-
34548860112
-
The Edinburgh human metabolic network reconstruction and its functional analysis
-
Ma HW, Sorokin A, Mazein A, Selkov A, Selkov E, Demin O, Goryanin I. The Edinburgh human metabolic network reconstruction and its functional analysis. Mol Syst Biol 2007, 3:8.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 8
-
-
Ma, H.W.1
Sorokin, A.2
Mazein, A.3
Selkov, A.4
Selkov, E.5
Demin, O.6
Goryanin, I.7
-
5
-
-
33846910173
-
Global reconstruction of the human metabolic network based on genomic and bibliomic data
-
10.1073/pnas.0610772104, 1794290, 17267599
-
Duarte NC, Becker SA, Jamshidi N, Thiele I, Mo ML, Vo TD, Srivas R, Palsson BO. Global reconstruction of the human metabolic network based on genomic and bibliomic data. Proc Natl Acad Sci USA 2007, 104:1777-1782. 10.1073/pnas.0610772104, 1794290, 17267599.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 1777-1782
-
-
Duarte, N.C.1
Becker, S.A.2
Jamshidi, N.3
Thiele, I.4
Mo, M.L.5
Vo, T.D.6
Srivas, R.7
Palsson, B.O.8
-
6
-
-
0142122303
-
Advances in flux balance analysis
-
10.1016/j.copbio.2003.08.001, 14580578
-
Kauffman KJ, Prakash P, Edwards JS. Advances in flux balance analysis. Current Opinion in Biotechnology 2003, 14:491-496. 10.1016/j.copbio.2003.08.001, 14580578.
-
(2003)
Current Opinion in Biotechnology
, vol.14
, pp. 491-496
-
-
Kauffman, K.J.1
Prakash, P.2
Edwards, J.S.3
-
7
-
-
51349092391
-
Network-based prediction of human tissue-specific metabolism
-
Shlomi T, Cabili MN, Herrgard MJ, Palsson BO, Ruppin E. Network-based prediction of human tissue-specific metabolism. Nat Biotech 2008, 26:1003-1010.
-
(2008)
Nat Biotech
, vol.26
, pp. 1003-1010
-
-
Shlomi, T.1
Cabili, M.N.2
Herrgard, M.J.3
Palsson, B.O.4
Ruppin, E.5
-
8
-
-
46249090791
-
Prediction of drug-target interaction networks from the integration of chemical and genomic spaces
-
10.1093/bioinformatics/btn162, 2718640, 18586719
-
Yamanishi Y, Araki M, Gutteridge A, Honda W, Kanehisa M. Prediction of drug-target interaction networks from the integration of chemical and genomic spaces. Bioinformatics 2008, 24:i232-240. 10.1093/bioinformatics/btn162, 2718640, 18586719.
-
(2008)
Bioinformatics
, vol.24
-
-
Yamanishi, Y.1
Araki, M.2
Gutteridge, A.3
Honda, W.4
Kanehisa, M.5
-
9
-
-
43449088832
-
A modular approach for integrative analysis of large-scale gene-expression and drug-response data
-
Kutalik Z, Beckmann JS, Bergmann S. A modular approach for integrative analysis of large-scale gene-expression and drug-response data. Nat Biotech 2008, 26:531-539.
-
(2008)
Nat Biotech
, vol.26
, pp. 531-539
-
-
Kutalik, Z.1
Beckmann, J.S.2
Bergmann, S.3
-
10
-
-
34548128437
-
Statistical prediction of protein chemical interactions based on chemical structure and mass spectrometry data
-
10.1093/bioinformatics/btm266, 17510168
-
Nagamine N, Sakakibara Y. Statistical prediction of protein chemical interactions based on chemical structure and mass spectrometry data. Bioinformatics 2007, 23:2004-2012. 10.1093/bioinformatics/btm266, 17510168.
-
(2007)
Bioinformatics
, vol.23
, pp. 2004-2012
-
-
Nagamine, N.1
Sakakibara, Y.2
-
11
-
-
47249146126
-
Drug Target Identification Using Side-Effect Similarity
-
10.1126/science.1158140, 18621671
-
Campillos M, Kuhn M, Gavin AC, Jensen LJ, Bork P. Drug Target Identification Using Side-Effect Similarity. Science 2008, 321:263-266. 10.1126/science.1158140, 18621671.
-
(2008)
Science
, vol.321
, pp. 263-266
-
-
Campillos, M.1
Kuhn, M.2
Gavin, A.C.3
Jensen, L.J.4
Bork, P.5
-
12
-
-
55449114287
-
The Activity Reaction Core and Plasticity of Metabolic Networks
-
10.1371/journal.pcbi.0010068, 1314881, 16362071
-
Almaas E, Oltvai ZN, Barabasi AL. The Activity Reaction Core and Plasticity of Metabolic Networks. PLoS Comput Biol 2005, 1:e68. 10.1371/journal.pcbi.0010068, 1314881, 16362071.
-
(2005)
PLoS Comput Biol
, vol.1
-
-
Almaas, E.1
Oltvai, Z.N.2
Barabasi, A.L.3
-
13
-
-
38449123881
-
An iterative algorithm for metabolic network-based drug target identification
-
full_text, 17992747
-
Sridhar P, Kahveci T, Ranka S. An iterative algorithm for metabolic network-based drug target identification. Pac Symp Biocomput 2007, 88-99. full_text, 17992747.
-
(2007)
Pac Symp Biocomput
, pp. 88-99
-
-
Sridhar, P.1
Kahveci, T.2
Ranka, S.3
-
15
-
-
34347258175
-
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox
-
Becker SA, Feist AM, Mo ML, Hannum G, Palsson BO, Herrgard MJ. Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox. Nat Protocols 2007, 2:727-738.
-
(2007)
Nat Protocols
, vol.2
, pp. 727-738
-
-
Becker, S.A.1
Feist, A.M.2
Mo, M.L.3
Hannum, G.4
Palsson, B.O.5
Herrgard, M.J.6
-
16
-
-
34147115178
-
Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study
-
MCT-1506-0650
-
Shankavaram UT, Reinhold WC, Nishizuka S, Major S, Morita D, Chary KK, Reimers MA, Scherf U, Kahn A, Dolginow D, et al. Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study. Mol Cancer Ther 2007, 1535-7163. MCT-1506-0650.
-
(2007)
Mol Cancer Ther
, pp. 1535-7163
-
-
Shankavaram, U.T.1
Reinhold, W.C.2
Nishizuka, S.3
Major, S.4
Morita, D.5
Chary, K.K.6
Reimers, M.A.7
Scherf, U.8
Kahn, A.9
Dolginow, D.10
-
17
-
-
33644874819
-
From genomics to chemical genomics: new developments in KEGG
-
10.1093/nar/gkj102, 1347464, 16381885
-
Kanehisa M, Goto S, Hattori M, Aoki-Kinoshita KF, Itoh M, Kawashima S, Katayama T, Araki M, Hirakawa M. From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res 2006, 34:D354-D357. 10.1093/nar/gkj102, 1347464, 16381885.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Kanehisa, M.1
Goto, S.2
Hattori, M.3
Aoki-Kinoshita, K.F.4
Itoh, M.5
Kawashima, S.6
Katayama, T.7
Araki, M.8
Hirakawa, M.9
-
18
-
-
35148838537
-
Drug-target network
-
Yildirim MA, Goh KI, Cusick ME, Barabasi AL, Vidal M. Drug-target network. Nat Biotech 2007, 25:1119-1126.
-
(2007)
Nat Biotech
, vol.25
, pp. 1119-1126
-
-
Yildirim, M.A.1
Goh, K.I.2
Cusick, M.E.3
Barabasi, A.L.4
Vidal, M.5
-
19
-
-
0242490780
-
Cytoscape: A software environment for integrated models of biomolecular interaction networks
-
Cold Spring Harbor Lab Press, Publications Dept
-
Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T. Cytoscape: A software environment for integrated models of biomolecular interaction networks. 3rd International Conference on Systems Biology 2002; Dec 13-15; Stockholm, Sweden 2002, 2498-2504. Cold Spring Harbor Lab Press, Publications Dept.
-
(2002)
3rd International Conference on Systems Biology 2002; Dec 13-15; Stockholm, Sweden
, pp. 2498-2504
-
-
Shannon, P.1
Markiel, A.2
Ozier, O.3
Baliga, N.S.4
Wang, J.T.5
Ramage, D.6
Amin, N.7
Schwikowski, B.8
Ideker, T.9
-
20
-
-
38549151817
-
DrugBank: a knowledgebase for drugs, drug actions and drug targets
-
10.1093/nar/gkm958, 2238889, 18048412
-
Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M. DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucl Acids Res 2008, 36:D901-906. 10.1093/nar/gkm958, 2238889, 18048412.
-
(2008)
Nucl Acids Res
, vol.36
-
-
Wishart, D.S.1
Knox, C.2
Guo, A.C.3
Cheng, D.4
Shrivastava, S.5
Tzur, D.6
Gautam, B.7
Hassanali, M.8
-
21
-
-
0035212059
-
Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution
-
10.1007/s100380170017, 11721885
-
Conrad S, Kauffmann HM, Ito K, Deeley RG, Cole SPC, Schrenk D. Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution. J Hum Genet 2001, 46:656-663. 10.1007/s100380170017, 11721885.
-
(2001)
J Hum Genet
, vol.46
, pp. 656-663
-
-
Conrad, S.1
Kauffmann, H.M.2
Ito, K.3
Deeley, R.G.4
Cole, S.P.C.5
Schrenk, D.6
-
22
-
-
0028567035
-
The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump
-
10.1073/pnas.91.19.8822, 44698, 7916458
-
Zaman GJ, Flens MJ, van Leusden MR, de Haas M, Mülder HS, Lankelma J, Pinedo HM, Scheper RJ, Baas F, Broxterman HJ. The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. Proceedings of the National Academy of Sciences of the United States of America 1994, 91:8822-8826. 10.1073/pnas.91.19.8822, 44698, 7916458.
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, pp. 8822-8826
-
-
Zaman, G.J.1
Flens, M.J.2
van Leusden, M.R.3
de Haas, M.4
Mülder, H.S.5
Lankelma, J.6
Pinedo, H.M.7
Scheper, R.J.8
Baas, F.9
Broxterman, H.J.10
-
23
-
-
0027960078
-
Pharmacological Characterization of Multidrug Resistant MRP-transfected Human Tumor Cells
-
Cole SPC, Sparks KE, Fraser K, Loe DW, Grant CE, Wilson GM, Deeley RG. Pharmacological Characterization of Multidrug Resistant MRP-transfected Human Tumor Cells. Cancer Res 1994, 54:5902-5910.
-
(1994)
Cancer Res
, vol.54
, pp. 5902-5910
-
-
Cole, S.P.C.1
Sparks, K.E.2
Fraser, K.3
Loe, D.W.4
Grant, C.E.5
Wilson, G.M.6
Deeley, R.G.7
-
24
-
-
0035369997
-
Kinetics of glutathione and daunorubicin efflux from multidrug resistance protein overexpressing small-cell lung cancer cells
-
10.1016/S0014-2999(01)00992-X, 11408043
-
Salerno M, Garnier-Suillerot A. Kinetics of glutathione and daunorubicin efflux from multidrug resistance protein overexpressing small-cell lung cancer cells. European Journal of Pharmacology 2001, 421:1-9. 10.1016/S0014-2999(01)00992-X, 11408043.
-
(2001)
European Journal of Pharmacology
, vol.421
, pp. 1-9
-
-
Salerno, M.1
Garnier-Suillerot, A.2
-
25
-
-
0028803254
-
2-Chloro-2'-deoxyadenosine (cladribine) and its analogues are good substrates and potent selective inhibitors of Escherichia coli purine-nucleoside phosphorylase
-
10.1111/j.1432-1033.1995.886_3.x, 8521855
-
Bzowska A, Kazimierczuk Z. 2-Chloro-2'-deoxyadenosine (cladribine) and its analogues are good substrates and potent selective inhibitors of Escherichia coli purine-nucleoside phosphorylase. European journal of biochemistry/FEBS 1995, 233:886-890. 10.1111/j.1432-1033.1995.886_3.x, 8521855.
-
(1995)
European journal of biochemistry/FEBS
, vol.233
, pp. 886-890
-
-
Bzowska, A.1
Kazimierczuk, Z.2
-
26
-
-
38449094885
-
Interaction between mercaptopurine and milk
-
10.1177/1078155207080802, 18045784
-
de Lemos ML, Hamata L, Jennings S, Leduc T. Interaction between mercaptopurine and milk. Journal of Oncology Pharmacy Practice 2007, 13:237-240. 10.1177/1078155207080802, 18045784.
-
(2007)
Journal of Oncology Pharmacy Practice
, vol.13
, pp. 237-240
-
-
de Lemos, M.L.1
Hamata, L.2
Jennings, S.3
Leduc, T.4
-
27
-
-
36549053255
-
The Role of Xanthine Oxidase in Thiopurine Metabolism: A Case Report
-
10.1097/FTD.0b013e31815bf4dc, 18043486
-
Wong DRP, Derijks LJJPP, den Dulk MOMD, Gemmeke EHKMP, Hooymans PMPP. The Role of Xanthine Oxidase in Thiopurine Metabolism: A Case Report. Therapeutic Drug Monitoring 2007, 29:845-848. 10.1097/FTD.0b013e31815bf4dc, 18043486.
-
(2007)
Therapeutic Drug Monitoring
, vol.29
, pp. 845-848
-
-
Wong, D.R.P.1
Derijks, L.J.J.P.P.2
den Dulk, M.O.M.D.3
Gemmeke, E.H.K.M.P.4
Hooymans, P.M.P.P.5
-
28
-
-
0000801240
-
Discovering regulatory and signalling circuits in molecular interaction networks
-
Ideker T, Ozier O, Schwikowski B, Siegel AF. Discovering regulatory and signalling circuits in molecular interaction networks. Bioinformatics 2002, 18:S233-240.
-
(2002)
Bioinformatics
, vol.18
-
-
Ideker, T.1
Ozier, O.2
Schwikowski, B.3
Siegel, A.F.4
|