A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported

DNA Repair

Volumn 12, Issue 9, 2013, Pages 699-706

  Galashevskaya, Anastasia ^a   Sarno, Antonio ^a   Vågbø, Cathrine B ^a   Aas, Per A ^a   Hagen, Lars ^a   Slupphaug, Geir ^a   Krokan, Hans E ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Activation induced cytidine deaminase; Adaptive immunity; Base excision repair; DNA damage; Uracil DNA glycosylase; Uracil in DNA

Indexed keywords

DEOXYRIBONUCLEOSIDE; DNA; URACIL; URACIL DNA GLYCOSIDASE;

ACCURACY; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA ISOLATION; ENZYME ACTIVITY; FIBROBLAST; GENOME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LYMPHOBLASTOID CELL; MASS SPECTROMETRY; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

2′-DEOXYCYTIDINE/2′-DEOXYURIDINE/2′-DEOXYRIBONUCLEOSIDE; ACTIVATION-INDUCED CYTIDINE DEAMINASE; ADAPTIVE IMMUNITY; BASE EXCISION REPAIR; DCYD/DURD/DN; DNA DAMAGE; LC/MS/MS; LIQUID CHROMATOGRAPHY COUPLED TO TANDEM MASS SPECTROMETRY; UNG; URACIL DNA GLYCOSYLASE; URACIL IN DNA; URACIL-DNA GLYCOSYLASE ENCODED BY THE UNG-GENE;

ANIMALS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; DNA; DNA CONTAMINATION; GENOME, HUMAN; HUMANS; HYDROLYSIS; LIMIT OF DETECTION; MICE; MICE, KNOCKOUT; REFERENCE STANDARDS; TANDEM MASS SPECTROMETRY; URACIL NUCLEOTIDES; URACIL-DNA GLYCOSIDASE;

MURINAE;

EID: 84880951449     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2013.05.002     Document Type: Article

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