Accumulation of true single strand breaks and AP sites in base excision repair deficient cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 694, Issue 1-2, 2010, Pages 65-71

  Luke, April M ^a   Chastain, Paul D ^b   Pachkowski, Brian F ^a   Afonin, Valeriy ^a   Takeda, Shunichi ^c   Kaufman, David G ^a,b   Swenberg, James A ^a,b   Nakamura, Jun ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Alkylating agent; AP sites; Base excision repair; O hydroxylamine; Single strand breaks

Indexed keywords

GENOMIC DNA; HYDROXYLAMINE; O (TETRAHYDRO 2H PYRAN 2 YL)HYDROXYLAMINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOMESYLIC ACID METHYL ESTER; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DNA DENATURATION; EXCISION REPAIR; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; HYDROGEN BOND; NULL CELL; PH; PRIORITY JOURNAL; SINGLE STRANDED DNA BREAK; SLOT BLOT HYBRIDIZATION;

ALKYLATING AGENTS; ANIMALS; CHICKENS; DNA; DNA DAMAGE; DNA REPAIR; ELECTROPHORESIS; HYDROGEN-ION CONCENTRATION; HYDROXYLAMINE; HYDROXYLAMINES; METHYL METHANESULFONATE; MUTAGENS; NADP; TIME FACTORS;

EID: 78649444388     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2010.08.008     Document Type: Article

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