Absence of 2′-deoxyoxanosine and presence of abasic sites in DNA exposed to nitric oxide at controlled physiological concentrations

Chemical Research in Toxicology

Volumn 16, Issue 9, 2003, Pages 1044-1055

  Dong, Min ^a   Wang, Chen ^b   Deen, William M ^a,b   Dedon, Peter C ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGUANOSINE; DEOXYINOSINE; DEOXYURIDINE; DNA; NITRIC OXIDE; PLASMID DNA; 2' DEOXYOXANOSINE; 2' DEOXYXANTHOSINE; 2'-DEOXYOXANOSINE; 2'-DEOXYXANTHOSINE; DEOXYRIBONUCLEOSIDE; DRUG DERIVATIVE; INOSINE; NITROGEN OXIDE; NITROGEN TRIOXIDE; OXYGEN; REACTIVE NITROGEN SPECIES;

ARTICLE; CYTOTOXICITY; GENOTOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFLAMMATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; CONFORMATION; DEAMINATION; DNA DAMAGE; DRUG EFFECT; METABOLISM; METHODOLOGY; PHYSIOLOGY; PLASMID;

DEAMINATION; DEOXYRIBONUCLEOSIDES; DEOXYURIDINE; DNA DAMAGE; INOSINE; MASS SPECTROMETRY; NITRIC OXIDE; NITROGEN OXIDES; NUCLEIC ACID CONFORMATION; OXYGEN; PLASMIDS; REACTIVE NITROGEN SPECIES;

EID: 0141848395     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx034046s     Document Type: Article

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