-
1
-
-
4043077961
-
Molecular mediators of hepatic steatosis and liver injury
-
DOI 10.1172/JCI200422422
-
J.D. Browning, and J.D. Horton Molecular mediators of hepatic steatosis and liver injury J Clin Invest 114 2004 147 152 (Pubitemid 39071617)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.2
, pp. 147-152
-
-
Browning, J.D.1
Horton, J.D.2
-
2
-
-
33845542745
-
Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
-
K. Morino, K.F. Petersen, and G.I. Shulman Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction Diabetes 55 2006 S9 S15
-
(2006)
Diabetes
, vol.55
-
-
Morino, K.1
Petersen, K.F.2
Shulman, G.I.3
-
3
-
-
4344582117
-
Epidemiology of non-alcoholic fatty liver
-
vii
-
C.E. Ruhl, and J.E. Everhart Epidemiology of non-alcoholic fatty liver Clin Liver Dis 8 2004 501 519 vii
-
(2004)
Clin Liver Dis
, vol.8
, pp. 501-519
-
-
Ruhl, C.E.1
Everhart, J.E.2
-
5
-
-
0032699670
-
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
-
S. Kersten, J. Seydoux, J.M. Peters, F.J. Gonzalez, B. Desvergne, and W. Wahli Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting J Clin Invest 103 1999 1489 1498
-
(1999)
J Clin Invest
, vol.103
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Peters, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
6
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders
-
DOI 10.1073/pnas.96.13.7473
-
T.C. Leone, C.J. Weinheimer, and D.P. Kelly A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders Proc Natl Acad Sci U S A 96 1999 7473 7478 (Pubitemid 29299686)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.13
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
7
-
-
0033998334
-
The PPARs: From orphan receptors to drug discovery
-
DOI 10.1021/jm990554g
-
T.M. Willson, P.J. Brown, D.D. Sternbach, and B.R. Henke The PPARs: from orphan receptors to drug discovery J Med Chem 43 2000 527 550 (Pubitemid 30127149)
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, Issue.4
, pp. 527-550
-
-
Willson, T.M.1
Brown, P.J.2
Sternbach, D.D.3
Henke, B.R.4
-
8
-
-
33644652183
-
Sorting out the roles of PPARα in energy metabolism and vascular homeostasis
-
DOI 10.1172/JCI27989
-
P. Lefebvre, G. Chinetti, J.C. Fruchart, and B. Staels Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis J Clin Invest 116 2006 571 580 (Pubitemid 43326861)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.3
, pp. 571-580
-
-
Lefebvre, P.1
Chinetti, G.2
Fruchart, J.-C.3
Staels, B.4
-
9
-
-
0030961960
-
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
-
I. Shimomura, H. Shimano, J.D. Horton, J.L. Goldstein, and M.S. Brown Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells J Clin Invest 99 1997 838 845 (Pubitemid 27123619)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.5
, pp. 838-845
-
-
Shimomura, I.1
Shimano, H.2
Horton, J.D.3
Goldstein, J.L.4
Brown, M.S.5
-
10
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
DOI 10.1172/JCI200215593
-
J.D. Horton, J.L. Goldstein, and M.S. Brown SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver J Clin Invest 109 2002 1125 1131 (Pubitemid 34496588)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.9
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
11
-
-
0345098365
-
The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse
-
DOI 10.1194/jlr.M300135-JLR200
-
J.W. Chisholm, J. Hong, S.A. Mills, and R.M. Lawn The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse J Lipid Res 44 2003 2039 2048 (Pubitemid 37509619)
-
(2003)
Journal of Lipid Research
, vol.44
, Issue.11
, pp. 2039-2048
-
-
Chisholm, J.W.1
Hong, J.2
Mills, S.A.3
Lawn, R.M.4
-
12
-
-
78149481592
-
Mammalian Kruppel-like factors in health and diseases
-
B.B. McConnell, and V.W. Yang Mammalian Kruppel-like factors in health and diseases Physiol Rev 90 2010 1337 1381
-
(2010)
Physiol Rev
, vol.90
, pp. 1337-1381
-
-
McConnell, B.B.1
Yang, V.W.2
-
13
-
-
0032475869
-
Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-β-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth
-
DOI 10.1074/jbc.273.40.25929
-
T. Cook, B. Gebelein, K. Mesa, A. Mladek, and R. Urrutia Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth J Biol Chem 273 1998 25929 25936 (Pubitemid 28475824)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.40
, pp. 25929-25936
-
-
Cook, T.1
Gebelein, B.2
Mesa, K.3
Mladek, A.4
Urrutia, R.5
-
14
-
-
73649098806
-
MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells
-
M.E. Fernandez-Zapico, J.C. van Velkinburgh, R. Gutierrez-Aguilar, B. Neve, P. Froguel, and R. Urrutia MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells J Biol Chem 284 2009 36482 36490
-
(2009)
J Biol Chem
, vol.284
, pp. 36482-36490
-
-
Fernandez-Zapico, M.E.1
Van Velkinburgh, J.C.2
Gutierrez-Aguilar, R.3
Neve, B.4
Froguel, P.5
Urrutia, R.6
-
15
-
-
80051527724
-
Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus
-
A. Bonnefond, G. Lomberk, N. Buttar, K. Busiah, E. Vaillant, and S. Lobbens Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus J Biol Chem 286 2011 28414 28424
-
(2011)
J Biol Chem
, vol.286
, pp. 28414-28424
-
-
Bonnefond, A.1
Lomberk, G.2
Buttar, N.3
Busiah, K.4
Vaillant, E.5
Lobbens, S.6
-
16
-
-
20144389645
-
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function
-
DOI 10.1073/pnas.0409177102
-
B. Neve, M.E. Fernandez-Zapico, V. Ashkenazi-Katalan, C. Dina, Y.H. Hamid, and E. Joly Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function Proc Natl Acad Sci U S A 102 2005 4807 4812 (Pubitemid 40471535)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.13
, pp. 4807-4812
-
-
Neve, B.1
Fernandez-Zapico, M.E.2
Ashkenazi-Katalan, V.3
Dina, C.4
Hamid, Y.H.5
Joly, E.6
Vaillant, E.7
Benmezroua, Y.8
Durand, E.9
Bakaher, N.10
Delannoy, V.11
Vaxillaire, M.12
Cook, T.13
Dallinga-Thie, G.M.14
Jansen, H.15
Charles, M.-A.16
Clement, K.17
Galan, P.18
Hercberg, S.19
Helbecque, N.20
Charpentier, G.21
Prentki, M.22
Hansen, T.23
Pedersen, O.24
Urrutia, R.25
Melloul, D.26
Froguel, P.27
more..
-
17
-
-
33947575572
-
Regulation of gluconeogenesis by Kruppel-like factor 15
-
S. Gray, B. Wang, Y. Orihuela, E.G. Hong, S. Fisch, and S. Haldar Regulation of gluconeogenesis by Kruppel-like factor 15 Cell Metab 5 2007 305 312
-
(2007)
Cell Metab
, vol.5
, pp. 305-312
-
-
Gray, S.1
Wang, B.2
Orihuela, Y.3
Hong, E.G.4
Fisch, S.5
Haldar, S.6
-
18
-
-
41449116010
-
Transcriptional Regulation of Adipogenesis by KLF4
-
DOI 10.1016/j.cmet.2008.02.001, PII S155041310800034X
-
K. Birsoy, Z. Chen, and J. Friedman Transcriptional regulation of adipogenesis by KLF4 Cell Metab 7 2008 339 347 (Pubitemid 351455215)
-
(2008)
Cell Metabolism
, vol.7
, Issue.4
, pp. 339-347
-
-
Birsoy, K.1
Chen, Z.2
Friedman, J.3
-
19
-
-
20144389501
-
Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation
-
DOI 10.1016/j.cmet.2004.11.005, PII S1550413104000063
-
Y. Oishi, I. Manabe, K. Tobe, K. Tsushima, T. Shindo, and K. Fujiu Kruppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation Cell Metab 1 2005 27 39 (Pubitemid 43960584)
-
(2005)
Cell Metabolism
, vol.1
, Issue.1
, pp. 27-39
-
-
Oishi, Y.1
Manabe, I.2
Tobe, K.3
Tsushima, K.4
Shindo, T.5
Fujiu, K.6
Nishimura, G.7
Maemura, K.8
Yamauchi, T.9
Kubota, N.10
Suzuki, R.11
Kitamura, T.12
Akira, S.13
Kadowaki, T.14
Nagai, R.15
-
20
-
-
0035514942
-
Adenovirus-Mediated Overexpression of Sterol Regulatory Element Binding Protein-1c Mimics Insulin Effects on Hepatic Gene Expression and Glucose Homeostasis in Diabetic Mice
-
D. Becard, I. Hainault, D. Azzout-Marniche, L. Bertry-Coussot, P. Ferre, and F. Foufelle Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice Diabetes 50 2001 2425 2430 (Pubitemid 33642757)
-
(2001)
Diabetes
, vol.50
, Issue.7-12
, pp. 2425-2430
-
-
Becard, D.1
Hainault, I.2
Azzout-Marniche, D.3
Bertry-Coussot, L.4
Ferre, P.5
Foufelle, F.6
-
21
-
-
84861809881
-
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
-
F. Benhamed, P.D. Denechaud, M. Lemoine, C. Robichon, M. Moldes, and J. Bertrand-Michel The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans J Clin Invest 122 2012 2176 2194
-
(2012)
J Clin Invest
, vol.122
, pp. 2176-2194
-
-
Benhamed, F.1
Denechaud, P.D.2
Lemoine, M.3
Robichon, C.4
Moldes, M.5
Bertrand-Michel, J.6
-
22
-
-
79953045550
-
Delivery of RNAi reagents in murine models of obesity and diabetes
-
D.M. Wilcox, R. Yang, S.J. Morgan, P.T. Nguyen, M.J. Voorbach, and P.M. Jung Delivery of RNAi reagents in murine models of obesity and diabetes J RNAi Gene Silencing 3 2006 225 236
-
(2006)
J RNAi Gene Silencing
, vol.3
, pp. 225-236
-
-
Wilcox, D.M.1
Yang, R.2
Morgan, S.J.3
Nguyen, P.T.4
Voorbach, M.J.5
Jung, P.M.6
-
23
-
-
10944224983
-
Functional study of transcription factor KLF11 by targeted gene inactivation
-
DOI 10.1016/j.bcmd.2004.08.027, PII S1079979604001846
-
C.Z. Song, G. Gavriilidis, H. Asano, and G. Stamatoyannopoulos Functional study of transcription factor KLF11 by targeted gene inactivation Blood Cells Mol Dis 34 2005 53 59 (Pubitemid 40017979)
-
(2005)
Blood Cells, Molecules, and Diseases
, vol.34
, Issue.1
, pp. 53-59
-
-
Song, C.-Z.1
Gavriilidis, G.2
Asano, H.3
Stamatoyannopoulos, G.4
-
24
-
-
0346256668
-
Liver Toxicities Typically Induced by First-Generation Adenoviral Vectors Can Be Reduced by Use of E1, E2b-Deleted Adenoviral Vectors
-
R.S. Everett, B.L. Hodges, E.Y. Ding, F. Xu, D. Serra, and A. Amalfitano Liver toxicities typically induced by first-generation adenoviral vectors can be reduced by use of E1, E2b-deleted adenoviral vectors Hum Gene Ther 14 2003 1715 1726 (Pubitemid 38010662)
-
(2003)
Human Gene Therapy
, vol.14
, Issue.18
, pp. 1715-1726
-
-
Everett, R.S.1
Hodges, B.L.2
Ding, E.Y.3
Xu, F.4
Serra, D.5
Amalfitano, A.6
-
25
-
-
0033541522
-
Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo
-
DOI 10.1089/10430349950018364
-
D.A. Muruve, M.J. Barnes, I.E. Stillman, and T.A. Libermann Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo Hum Gene Ther 10 1999 965 976 (Pubitemid 29195426)
-
(1999)
Human Gene Therapy
, vol.10
, Issue.6
, pp. 965-976
-
-
Muruve, D.A.1
Barnes, M.J.2
Stillman, I.E.3
Libermann, T.A.4
-
26
-
-
77649337140
-
Non-alcoholic fatty liver disease: Pathology and pathogenesis
-
D.G. Tiniakos, M.B. Vos, and E.M. Brunt Non-alcoholic fatty liver disease: pathology and pathogenesis Annu Rev Pathol 5 2010 145 171
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 145-171
-
-
Tiniakos, D.G.1
Vos, M.B.2
Brunt, E.M.3
-
27
-
-
69449086702
-
Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human
-
M. Rakhshandehroo, G. Hooiveld, M. Muller, and S. Kersten Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human PLoS One 4 2009 e6796
-
(2009)
PLoS One
, vol.4
, pp. 6796
-
-
Rakhshandehroo, M.1
Hooiveld, G.2
Muller, M.3
Kersten, S.4
-
28
-
-
34250378403
-
A protocol for rapid generation of recombinant adenoviruses using the AdEasy system
-
DOI 10.1038/nprot.2007.135, PII NPROT.2007.135
-
J. Luo, Z.L. Deng, X. Luo, N. Tang, W.X. Song, and J. Chen A protocol for rapid generation of recombinant adenoviruses using the AdEasy system Nat Protoc 2 2007 1236 1247 (Pubitemid 46908240)
-
(2007)
Nature Protocols
, vol.2
, Issue.5
, pp. 1236-1247
-
-
Luo, J.1
Deng, Z.-L.2
Luo, X.3
Tang, N.4
Song, W.-X.5
Chen, J.6
Sharff, K.A.7
Luu, H.H.8
Haydon, R.C.9
Kinzler, K.W.10
Vogelstein, B.11
He, T.-C.12
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