-
1
-
-
0030578874
-
Insulin resistance and diabetes mellitus
-
8887011 10.1016/1056-8727(96)00046-3 1:STN:280:DyaK2s%2FktFOnsg%3D%3D
-
DeFronzo RA, Prato SD (1996) Insulin resistance and diabetes mellitus. J Diabetes Complicat 10(5):243-245
-
(1996)
J Diabetes Complicat
, vol.10
, Issue.5
, pp. 243-245
-
-
Defronzo, R.A.1
Prato, S.D.2
-
2
-
-
1442275317
-
Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes
-
14988310 10.2337/diacare.27.3.813
-
Pickup JC (2004) Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diabetes Care 27(3):813-823
-
(2004)
Diabetes Care
, vol.27
, Issue.3
, pp. 813-823
-
-
Pickup, J.C.1
-
3
-
-
23644446750
-
Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: Association with cytokine expression, insulin resistance, and reduction by pioglitazone
-
16046295 10.2337/diabetes.54.8.2305 1:CAS:528:DC%2BD2MXnt1ynsbk%3D
-
Di Gregorio GB, Yao-Borengasser A, Rasouli N, Varma V, Lu T, Miles LM, Ranganathan G, Peterson CA, McGehee RE, Kern PA (2005) Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone. Diabetes 54(8):2305-2313
-
(2005)
Diabetes
, vol.54
, Issue.8
, pp. 2305-2313
-
-
Di Gregorio, G.B.1
Yao-Borengasser, A.2
Rasouli, N.3
Varma, V.4
Lu, T.5
Miles, L.M.6
Ranganathan, G.7
Peterson, C.A.8
McGehee, R.E.9
Kern, P.A.10
-
4
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
10.1172/JCI19451 14679177 1:CAS:528:DC%2BD3sXhtVSmtLvI
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112(12):1821-1830. doi: 10.1172/JCI19451
-
(2003)
J Clin Invest
, vol.112
, Issue.12
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
5
-
-
34548431826
-
Increased number of islet-associated macrophages in type 2 diabetes
-
10.2337/db06-1650 17579207 10.2337/db06-1650 1:CAS:528:DC%2BD2sXhtV2gs7fE
-
Ehses JA, Perren A, Eppler E, Ribaux P, Pospisilik JA, Maor-Cahn R, Gueripel X, Ellingsgaard H, Schneider MK, Biollaz G, Fontana A, Reinecke M, Homo-Delarche F, Donath MY (2007) Increased number of islet-associated macrophages in type 2 diabetes. Diabetes 56(9):2356-2370. doi: 10.2337/db06-1650
-
(2007)
Diabetes
, vol.56
, Issue.9
, pp. 2356-2370
-
-
Ehses, J.A.1
Perren, A.2
Eppler, E.3
Ribaux, P.4
Pospisilik, J.A.5
Maor-Cahn, R.6
Gueripel, X.7
Ellingsgaard, H.8
Schneider, M.K.9
Biollaz, G.10
Fontana, A.11
Reinecke, M.12
Homo-Delarche, F.13
Donath, M.Y.14
-
6
-
-
0142153909
-
Innate immunity in the liver
-
15703606 10.1097/00001574-200311000-00009
-
Li Z, Diehl AM (2003) Innate immunity in the liver. Curr Opin Gastroenterol 19(6):565-571
-
(2003)
Curr Opin Gastroenterol
, vol.19
, Issue.6
, pp. 565-571
-
-
Li, Z.1
Diehl, A.M.2
-
7
-
-
0035023128
-
Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
-
11287357 1:CAS:528:DC%2BD3MXjsVahs7s%3D
-
Kern PA, Ranganathan S, Li C, Wood L, Ranganathan G (2001) Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 280(5):E745-E751
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
, Issue.5
-
-
Kern, P.A.1
Ranganathan, S.2
Li, C.3
Wood, L.4
Ranganathan, G.5
-
8
-
-
0030864185
-
Targeted disruption of the tumor necrosis factor-alpha gene: Metabolic consequences in obese and nonobese mice
-
9287059 10.2337/diabetes.46.9.1526 1:CAS:528:DyaK2sXlvFemsro%3D
-
Ventre J, Doebber T, Wu M, MacNaul K, Stevens K, Pasparakis M, Kollias G, Moller DE (1997) Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese mice. Diabetes 46(9):1526-1531
-
(1997)
Diabetes
, vol.46
, Issue.9
, pp. 1526-1531
-
-
Ventre, J.1
Doebber, T.2
Wu, M.3
MacNaul, K.4
Stevens, K.5
Pasparakis, M.6
Kollias, G.7
Moller, D.E.8
-
9
-
-
0036098188
-
Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitro
-
11994345 10.1210/jc.87.5.2084 1:CAS:528:DC%2BD38XjsFGhtLo%3D
-
Bastard JP, Maachi M, Van Nhieu JT, Jardel C, Bruckert E, Grimaldi A, Robert JJ, Capeau J, Hainque B (2002) Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitro. J Clin Endocrinol Metab 87(5):2084-2089
-
(2002)
J Clin Endocrinol Metab
, vol.87
, Issue.5
, pp. 2084-2089
-
-
Bastard, J.P.1
Maachi, M.2
Van Nhieu, J.T.3
Jardel, C.4
Bruckert, E.5
Grimaldi, A.6
Robert, J.J.7
Capeau, J.8
Hainque, B.9
-
10
-
-
0030735542
-
Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo
-
9398739 10.1210/jc.82.12.4196 1:CAS:528:DyaK2sXnvFyrsrw%3D
-
Mohamed-Ali V, Goodrick S, Rawesh A, Katz DR, Miles JM, Yudkin JS, Klein S, Coppack SW (1997) Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J Clin Endocrinol Metab 82(12):4196-4200
-
(1997)
J Clin Endocrinol Metab
, vol.82
, Issue.12
, pp. 4196-4200
-
-
Mohamed-Ali, V.1
Goodrick, S.2
Rawesh, A.3
Katz, D.R.4
Miles, J.M.5
Yudkin, J.S.6
Klein, S.7
Coppack, S.W.8
-
11
-
-
0027421831
-
Interleukin-6 in biology and medicine
-
8379461 10.1016/S0065-2776(08)60532-5 1:CAS:528:DyaK3sXms1yitLY%3D
-
Akira S, Taga T, Kishimoto T (1993) Interleukin-6 in biology and medicine. Adv Immunol 54:1-78
-
(1993)
Adv Immunol
, vol.54
, pp. 1-78
-
-
Akira, S.1
Taga, T.2
Kishimoto, T.3
-
12
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
-
10.1172/JCI117936 7738205 10.1172/JCI117936 1:CAS:528:DyaK2MXltlWru70%3D
-
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM (1995) Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 95(5):2409-2415. doi: 10.1172/JCI117936
-
(1995)
J Clin Invest
, vol.95
, Issue.5
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
13
-
-
0035908632
-
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
-
11466099 10.1001/jama.286.3.327 1:STN:280:DC%2BD3MvisVCmug%3D%3D
-
Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM (2001) C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 286(3):327-334
-
(2001)
JAMA
, vol.286
, Issue.3
, pp. 327-334
-
-
Pradhan, A.D.1
Manson, J.E.2
Rifai, N.3
Buring, J.E.4
Ridker, P.M.5
-
14
-
-
44749084540
-
Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice
-
10.1007/s00125-008-0998-8 18437347 10.1007/s00125-008-0998-8 1:CAS:528:DC%2BD1cXmslWhurc%3D
-
Franckhauser S, Elias I, Rotter Sopasakis V, Ferre T, Nagaev I, Andersson CX, Agudo J, Ruberte J, Bosch F, Smith U (2008) Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice. Diabetologia 51(7):1306-1316. doi: 10.1007/s00125-008-0998-8
-
(2008)
Diabetologia
, vol.51
, Issue.7
, pp. 1306-1316
-
-
Franckhauser, S.1
Elias, I.2
Rotter Sopasakis, V.3
Ferre, T.4
Nagaev, I.5
Andersson, C.X.6
Agudo, J.7
Ruberte, J.8
Bosch, F.9
Smith, U.10
-
15
-
-
0033678516
-
Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss
-
10999830 10.1210/jc.85.9.3338 1:CAS:528:DC%2BD3cXmsVKqsb4%3D
-
Bastard JP, Jardel C, Bruckert E, Blondy P, Capeau J, Laville M, Vidal H, Hainque B (2000) Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss. J Clin Endocrinol Metab 85(9):3338-3342
-
(2000)
J Clin Endocrinol Metab
, vol.85
, Issue.9
, pp. 3338-3342
-
-
Bastard, J.P.1
Jardel, C.2
Bruckert, E.3
Blondy, P.4
Capeau, J.5
Laville, M.6
Vidal, H.7
Hainque, B.8
-
16
-
-
0030782520
-
Dose-dependent effects of recombinant human interleukin-6 on glucose regulation
-
9398733 10.1210/jc.82.12.4167 1:CAS:528:DyaK2sXnvFyku7o%3D
-
Tsigos C, Papanicolaou DA, Kyrou I, Defensor R, Mitsiadis CS, Chrousos GP (1997) Dose-dependent effects of recombinant human interleukin-6 on glucose regulation. J Clin Endocrinol Metab 82(12):4167-4170
-
(1997)
J Clin Endocrinol Metab
, vol.82
, Issue.12
, pp. 4167-4170
-
-
Tsigos, C.1
Papanicolaou, D.A.2
Kyrou, I.3
Defensor, R.4
Mitsiadis, C.S.5
Chrousos, G.P.6
-
17
-
-
0032922944
-
Circulating tumor necrosis factor-alpha concentrations in a native Canadian population with high rates of type 2 diabetes mellitus
-
9920095 10.1210/jc.84.1.272 1:CAS:528:DyaK1MXmslWrtg%3D%3D
-
Zinman B, Hanley AJ, Harris SB, Kwan J, Fantus IG (1999) Circulating tumor necrosis factor-alpha concentrations in a native Canadian population with high rates of type 2 diabetes mellitus. J Clin Endocrinol Metab 84(1):272-278
-
(1999)
J Clin Endocrinol Metab
, vol.84
, Issue.1
, pp. 272-278
-
-
Zinman, B.1
Hanley, A.J.2
Harris, S.B.3
Kwan, J.4
Fantus, I.G.5
-
18
-
-
0026549669
-
Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output
-
1727716 10.1210/en.130.1.43 1:CAS:528:DyaK38XlslSqtQ%3D%3D
-
Lang CH, Dobrescu C, Bagby GJ (1992) Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output. Endocrinology 130(1):43-52
-
(1992)
Endocrinology
, vol.130
, Issue.1
, pp. 43-52
-
-
Lang, C.H.1
Dobrescu, C.2
Bagby, G.J.3
-
19
-
-
25844456730
-
Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation
-
16186396 10.2337/diabetes.54.10.2939 1:CAS:528:DC%2BD2MXhtV2rs7%2FJ
-
Plomgaard P, Bouzakri K, Krogh-Madsen R, Mittendorfer B, Zierath JR, Pedersen BK (2005) Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes 54(10):2939-2945
-
(2005)
Diabetes
, vol.54
, Issue.10
, pp. 2939-2945
-
-
Plomgaard, P.1
Bouzakri, K.2
Krogh-Madsen, R.3
Mittendorfer, B.4
Zierath, J.R.5
Pedersen, B.K.6
-
20
-
-
34948846112
-
Mice heterozygous for tumor necrosis factor-alpha converting enzyme are protected from obesity-induced insulin resistance and diabetes
-
10.2337/db07-0360 17646208 10.2337/db07-0360 1:CAS:528:DC%2BD2sXhtFygt7zL
-
Serino M, Menghini R, Fiorentino L, Amoruso R, Mauriello A, Lauro D, Sbraccia P, Hribal ML, Lauro R, Federici M (2007) Mice heterozygous for tumor necrosis factor-alpha converting enzyme are protected from obesity-induced insulin resistance and diabetes. Diabetes 56(10):2541-2546. doi: 10.2337/db07-0360
-
(2007)
Diabetes
, vol.56
, Issue.10
, pp. 2541-2546
-
-
Serino, M.1
Menghini, R.2
Fiorentino, L.3
Amoruso, R.4
Mauriello, A.5
Lauro, D.6
Sbraccia, P.7
Hribal, M.L.8
Lauro, R.9
Federici, M.10
-
21
-
-
69949130225
-
Impaired regulation of the TNF-alpha converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: A new mechanism of insulin resistance in humans
-
10.1007/s00125-009-1451-3 19633828 10.1007/s00125-009-1451-3 1:CAS:528:DC%2BD1MXhtVygtLnJ
-
Monroy A, Kamath S, Chavez AO, Centonze VE, Veerasamy M, Barrentine A, Wewer JJ, Coletta DK, Jenkinson C, Jhingan RM, Smokler D, Reyna S, Musi N, Khokka R, Federici M, Tripathy D, DeFronzo RA, Folli F (2009) Impaired regulation of the TNF-alpha converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: a new mechanism of insulin resistance in humans. Diabetologia 52(10):2169-2181. doi: 10.1007/s00125-009-1451-3
-
(2009)
Diabetologia
, vol.52
, Issue.10
, pp. 2169-2181
-
-
Monroy, A.1
Kamath, S.2
Chavez, A.O.3
Centonze, V.E.4
Veerasamy, M.5
Barrentine, A.6
Wewer, J.J.7
Coletta, D.K.8
Jenkinson, C.9
Jhingan, R.M.10
Smokler, D.11
Reyna, S.12
Musi, N.13
Khokka, R.14
Federici, M.15
Tripathy, D.16
Defronzo, R.A.17
Folli, F.18
-
22
-
-
0036894360
-
Interleukin-6 induces cellular insulin resistance in hepatocytes
-
12453891 10.2337/diabetes.51.12.3391 1:CAS:528:DC%2BD38Xptl2ntbk%3D
-
Senn JJ, Klover PJ, Nowak IA, Mooney RA (2002) Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes 51(12):3391-3399
-
(2002)
Diabetes
, vol.51
, Issue.12
, pp. 3391-3399
-
-
Senn, J.J.1
Klover, P.J.2
Nowak, I.A.3
Mooney, R.A.4
-
23
-
-
0242580711
-
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
-
10.1074/jbc.M301977200 12952969 10.1074/jbc.M301977200 1:CAS:528:DC%2BD3sXosl2itrs%3D
-
Rotter V, Nagaev I, Smith U (2003) Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem 278(46):45777-45784. doi: 10.1074/jbc.M301977200
-
(2003)
J Biol Chem
, vol.278
, Issue.46
, pp. 45777-45784
-
-
Rotter, V.1
Nagaev, I.2
Smith, U.3
-
24
-
-
23944441084
-
Activation of opioid mu-receptors by loperamide to improve interleukin-6-induced inhibition of insulin signals in myoblast C2C12 cells
-
10.1007/s00125-005-1791-6 15959754 10.1007/s00125-005-1791-6 1:CAS:528:DC%2BD2MXmtlCktLk%3D
-
Tzeng TF, Liu IM, Cheng JT (2005) Activation of opioid mu-receptors by loperamide to improve interleukin-6-induced inhibition of insulin signals in myoblast C2C12 cells. Diabetologia 48(7):1386-1392. doi: 10.1007/s00125-005- 1791-6
-
(2005)
Diabetologia
, vol.48
, Issue.7
, pp. 1386-1392
-
-
Tzeng, T.F.1
Liu, I.M.2
Cheng, J.T.3
-
25
-
-
33745187112
-
Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes
-
10.1016/j.bbrc.2006.05.170 16781673 10.1016/j.bbrc.2006.05.170 1:CAS:528:DC%2BD28XmtlWrsLs%3D
-
Song MJ, Kim KH, Yoon JM, Kim JB (2006) Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. Biochem Biophys Res Commun 346(3):739-745. doi: 10.1016/j.bbrc.2006.05.170
-
(2006)
Biochem Biophys Res Commun
, vol.346
, Issue.3
, pp. 739-745
-
-
Song, M.J.1
Kim, K.H.2
Yoon, J.M.3
Kim, J.B.4
-
26
-
-
33748755008
-
Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes
-
10.1074/jbc.M513304200 16798732 10.1074/jbc.M513304200 1:CAS:528:DC%2BD28XptlKmsro%3D
-
Senn JJ (2006) Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes. J Biol Chem 281(37):26865-26875. doi: 10.1074/jbc.M513304200
-
(2006)
J Biol Chem
, vol.281
, Issue.37
, pp. 26865-26875
-
-
Senn, J.J.1
-
27
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
10.1172/JCI28898 17053832 10.1172/JCI28898 1:CAS:528:DC%2BD28XhtFyrsLfE
-
Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS (2006) TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116(11):3015-3025. doi: 10.1172/JCI28898
-
(2006)
J Clin Invest
, vol.116
, Issue.11
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
28
-
-
34547602916
-
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
-
10.2337/db06-1595 17519423 10.2337/db06-1595 1:CAS:528: DC%2BD2sXos12qsrY%3D
-
Tsukumo DM, Carvalho-Filho MA, Carvalheira JB, Prada PO, Hirabara SM, Schenka AA, Araujo EP, Vassallo J, Curi R, Velloso LA, Saad MJ (2007) Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes 56(8):1986-1998. doi: 10.2337/db06-1595
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 1986-1998
-
-
Tsukumo, D.M.1
Carvalho-Filho, M.A.2
Carvalheira, J.B.3
Prada, P.O.4
Hirabara, S.M.5
Schenka, A.A.6
Araujo, E.P.7
Vassallo, J.8
Curi, R.9
Velloso, L.A.10
Saad, M.J.11
-
29
-
-
57449083385
-
Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet
-
10.1677/JOE-08-0354 18787058 10.1677/JOE-08-0354 1:CAS:528: DC%2BD1cXhsFemur7M
-
Caricilli AM, Nascimento PH, Pauli JR, Tsukumo DM, Velloso LA, Carvalheira JB, Saad MJ (2008) Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet. J Endocrinol 199(3):399-406. doi: 10.1677/JOE-08-0354
-
(2008)
J Endocrinol
, vol.199
, Issue.3
, pp. 399-406
-
-
Caricilli, A.M.1
Nascimento, P.H.2
Pauli, J.R.3
Tsukumo, D.M.4
Velloso, L.A.5
Carvalheira, J.B.6
Saad, M.J.7
-
30
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
-
10.1074/jbc.M706762200 17916553 10.1074/jbc.M706762200 1:CAS:528:DC%2BD2sXhtlCrtLzP
-
Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM (2007) A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem 282(48):35279-35292. doi: 10.1074/jbc.M706762200
-
(2007)
J Biol Chem
, vol.282
, Issue.48
, pp. 35279-35292
-
-
Nguyen, M.T.1
Favelyukis, S.2
Nguyen, A.K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-Bryan, R.7
Glass, C.K.8
Neels, J.G.9
Olefsky, J.M.10
-
31
-
-
66849093697
-
Muscle inflammatory response and insulin resistance: Synergistic interaction between macrophages and fatty acids leads to impaired insulin action
-
10.1152/ajpendo.90885.2008 19336660 10.1152/ajpendo.90885.2008 1:CAS:528:DC%2BD1MXnsVClt7c%3D
-
Varma V, Yao-Borengasser A, Rasouli N, Nolen GT, Phanavanh B, Starks T, Gurley C, Simpson P, McGehee RE Jr, Kern PA, Peterson CA (2009) Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action. Am J Physiol Endocrinol Metab 296(6):E1300-E1310. doi: 10.1152/ajpendo.90885.2008
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, Issue.6
-
-
Varma, V.1
Yao-Borengasser, A.2
Rasouli, N.3
Nolen, G.T.4
Phanavanh, B.5
Starks, T.6
Gurley, C.7
Simpson, P.8
McGehee, Jr.R.E.9
Kern, P.A.10
Peterson, C.A.11
-
32
-
-
59349095031
-
Classical PKC is not associated with defective insulin signaling in patients with impaired glucose tolerance
-
10.1016/j.diabres.2008.11.035 19124171 10.1016/j.diabres.2008.11.035
-
Kim do M, Jang HJ, Han SJ, Ha ES, Kim YK, Park JW, Song KE, Jung SH, Ahn SM, Choi SE, Kim HJ, Kim DJ, Lee HC, Lee KW (2009) Classical PKC is not associated with defective insulin signaling in patients with impaired glucose tolerance. Diabetes Res Clin Pract 83(3):334-340. doi: 10.1016/j.diabres.2008. 11.035
-
(2009)
Diabetes Res Clin Pract
, vol.83
, Issue.3
, pp. 334-340
-
-
Kim Do, M.1
Jang, H.J.2
Han, S.J.3
Ha, E.S.4
Kim, Y.K.5
Park, J.W.6
Song, K.E.7
Jung, S.H.8
Ahn, S.M.9
Choi, S.E.10
Kim, H.J.11
Kim, D.J.12
Lee, H.C.13
Lee, K.W.14
-
33
-
-
0018602014
-
Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance
-
National Diabetes Data Group
-
National Diabetes Data Group (1979) Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 28(12):1039-1057
-
(1979)
Diabetes
, vol.28
, Issue.12
, pp. 1039-1057
-
-
-
34
-
-
0018520840
-
Glucose clamp technique: A method for quantifying insulin secretion and resistance
-
382871 1:CAS:528:DyaE1MXlslWhs70%3D
-
DeFronzo RA, Tobin JD, Andres R (1979) Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237(3):E214-E223
-
(1979)
Am J Physiol
, vol.237
, Issue.3
-
-
Defronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
35
-
-
0035805629
-
Palmitate-induced apoptosis can occur through a ceramide-independent pathway
-
10.1074/jbc.M010286200 11278654 10.1074/jbc.M010286200 1:CAS:528:DC%2BD3MXjs1Orsro%3D
-
Listenberger LL, Ory DS, Schaffer JE (2001) Palmitate-induced apoptosis can occur through a ceramide-independent pathway. J Biol Chem 276(18):14890-14895. doi: 10.1074/jbc.M010286200
-
(2001)
J Biol Chem
, vol.276
, Issue.18
, pp. 14890-14895
-
-
Listenberger, L.L.1
Ory, D.S.2
Schaffer, J.E.3
-
36
-
-
0027474061
-
Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins
-
7680921 1:CAS:528:DyaK3sXkvV2gsrw%3D
-
Holness CL, Simmons DL (1993) Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins. Blood 81(6):1607-1613
-
(1993)
Blood
, vol.81
, Issue.6
, pp. 1607-1613
-
-
Holness, C.L.1
Simmons, D.L.2
-
37
-
-
33644952935
-
Aging alters macrophage properties in human skeletal muscle both at rest and in response to acute resistance exercise
-
10.1016/j.exger.2005.12.007 16457979 10.1016/j.exger.2005.12.007 1:CAS:528:DC%2BD28Xis1entrs%3D
-
Przybyla B, Gurley C, Harvey JF, Bearden E, Kortebein P, Evans WJ, Sullivan DH, Peterson CA, Dennis RA (2006) Aging alters macrophage properties in human skeletal muscle both at rest and in response to acute resistance exercise. Exp Gerontol 41(3):320-327. doi: 10.1016/j.exger.2005.12.007
-
(2006)
Exp Gerontol
, vol.41
, Issue.3
, pp. 320-327
-
-
Przybyla, B.1
Gurley, C.2
Harvey, J.F.3
Bearden, E.4
Kortebein, P.5
Evans, W.J.6
Sullivan, D.H.7
Peterson, C.A.8
Dennis, R.A.9
-
38
-
-
12344266697
-
How obesity causes diabetes: Not a tall tale
-
10.1126/science.1104342 15662001 10.1126/science.1104342 1:CAS:528:DC%2BD2MXksFyhsA%3D%3D
-
Lazar MA (2005) How obesity causes diabetes: not a tall tale. Science 307(5708):373-375. doi: 10.1126/science.1104342
-
(2005)
Science
, vol.307
, Issue.5708
, pp. 373-375
-
-
Lazar, M.A.1
-
39
-
-
12144290761
-
Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo
-
15047622 10.2337/diabetes.53.4.1060 1:CAS:528:DC%2BD2cXivFyqsbg%3D
-
Kim HJ, Higashimori T, Park SY, Choi H, Dong J, Kim YJ, Noh HL, Cho YR, Cline G, Kim YB, Kim JK (2004) Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo. Diabetes 53(4):1060-1067
-
(2004)
Diabetes
, vol.53
, Issue.4
, pp. 1060-1067
-
-
Kim, H.J.1
Higashimori, T.2
Park, S.Y.3
Choi, H.4
Dong, J.5
Kim, Y.J.6
Noh, H.L.7
Cho, Y.R.8
Cline, G.9
Kim, Y.B.10
Kim, J.K.11
-
40
-
-
34249682779
-
Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle
-
10.2337/db06-1733 17363741 10.2337/db06-1733 1:CAS:528: DC%2BD2sXmtlKhs78%3D
-
Glund S, Deshmukh A, Long YC, Moller T, Koistinen HA, Caidahl K, Zierath JR, Krook A (2007) Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle. Diabetes 56(6):1630-1637. doi: 10.2337/db06-1733
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1630-1637
-
-
Glund, S.1
Deshmukh, A.2
Long, Y.C.3
Moller, T.4
Koistinen, H.A.5
Caidahl, K.6
Zierath, J.R.7
Krook, A.8
-
41
-
-
33751501694
-
Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle
-
10.1210/me.2005-0490 16945991 10.1210/me.2005-0490 1:CAS:528: DC%2BD28XhtlWks7%2FE
-
Al-Khalili L, Bouzakri K, Glund S, Lonnqvist F, Koistinen HA, Krook A (2006) Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle. Mol Endocrinol 20(12):3364-3375. doi: 10.1210/me.2005-0490
-
(2006)
Mol Endocrinol
, vol.20
, Issue.12
, pp. 3364-3375
-
-
Al-Khalili, L.1
Bouzakri, K.2
Glund, S.3
Lonnqvist, F.4
Koistinen, H.A.5
Krook, A.6
-
42
-
-
33750859187
-
Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase
-
10.2337/db05-1404 17003332 10.2337/db05-1404 1:CAS:528:DC%2BD28XhtVGlsrnP
-
Carey AL, Steinberg GR, Macaulay SL, Thomas WG, Holmes AG, Ramm G, Prelovsek O, Hohnen-Behrens C, Watt MJ, James DE, Kemp BE, Pedersen BK, Febbraio MA (2006) Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase. Diabetes 55(10):2688-2697. doi: 10.2337/db05-1404
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2688-2697
-
-
Carey, A.L.1
Steinberg, G.R.2
MacAulay, S.L.3
Thomas, W.G.4
Holmes, A.G.5
Ramm, G.6
Prelovsek, O.7
Hohnen-Behrens, C.8
Watt, M.J.9
James, D.E.10
Kemp, B.E.11
Pedersen, B.K.12
Febbraio, M.A.13
-
43
-
-
58149345626
-
Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle
-
10.2337/db07-1062 18796617 10.2337/db07-1062 1:CAS:528: DC%2BD1MXhsleisbs%3D
-
Nieto-Vazquez I, Fernandez-Veledo S, de Alvaro C, Lorenzo M (2008) Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle. Diabetes 57(12):3211-3221. doi: 10.2337/db07-1062
-
(2008)
Diabetes
, vol.57
, Issue.12
, pp. 3211-3221
-
-
Nieto-Vazquez, I.1
Fernandez-Veledo, S.2
De Alvaro, C.3
Lorenzo, M.4
-
44
-
-
37549013749
-
Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle
-
10.1007/s00125-007-0861-3 18060381 10.1007/s00125-007-0861-3 1:CAS:528:DC%2BD1cXlt12k
-
Radin MS, Sinha S, Bhatt BA, Dedousis N, O'Doherty RM (2008) Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle. Diabetologia 51(2):336-346. doi: 10.1007/s00125-007-0861-3
-
(2008)
Diabetologia
, vol.51
, Issue.2
, pp. 336-346
-
-
Radin, M.S.1
Sinha, S.2
Bhatt, B.A.3
Dedousis, N.4
O'Doherty, R.M.5
-
45
-
-
58149359307
-
Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects
-
10.2337/db08-0038 18633101 10.2337/db08-0038 1:CAS:528: DC%2BD1MXhs1Knsb4%3D
-
Reyna SM, Ghosh S, Tantiwong P, Meka CS, Eagan P, Jenkinson CP, Cersosimo E, Defronzo RA, Coletta DK, Sriwijitkamol A, Musi N (2008) Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects. Diabetes 57(10):2595-2602. doi: 10.2337/db08-0038
-
(2008)
Diabetes
, vol.57
, Issue.10
, pp. 2595-2602
-
-
Reyna, S.M.1
Ghosh, S.2
Tantiwong, P.3
Meka, C.S.4
Eagan, P.5
Jenkinson, C.P.6
Cersosimo, E.7
Defronzo, R.A.8
Coletta, D.K.9
Sriwijitkamol, A.10
Musi, N.11
-
46
-
-
0024157116
-
Genomic structure of the murine IL-6 gene. High degree conservation of potential regulatory sequences between mouse and human
-
3263439 1:CAS:528:DyaL1MXkslaiurw%3D
-
Tanabe O, Akira S, Kamiya T, Wong GG, Hirano T, Kishimoto T (1988) Genomic structure of the murine IL-6 gene. High degree conservation of potential regulatory sequences between mouse and human. J Immunol 141(11):3875-3881
-
(1988)
J Immunol
, vol.141
, Issue.11
, pp. 3875-3881
-
-
Tanabe, O.1
Akira, S.2
Kamiya, T.3
Wong, G.G.4
Hirano, T.5
Kishimoto, T.6
-
47
-
-
0035851208
-
ERK and p38 MAPK, but not NF-kappaB, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts
-
11597988 10.1161/hh2001.098873 1:CAS:528:DC%2BD3MXnsF2kt70%3D
-
Sano M, Fukuda K, Sato T, Kawaguchi H, Suematsu M, Matsuda S, Koyasu S, Matsui H, Yamauchi-Takihara K, Harada M, Saito Y, Ogawa S (2001) ERK and p38 MAPK, but not NF-kappaB, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts. Circ Res 89(8):661-669
-
(2001)
Circ Res
, vol.89
, Issue.8
, pp. 661-669
-
-
Sano, M.1
Fukuda, K.2
Sato, T.3
Kawaguchi, H.4
Suematsu, M.5
Matsuda, S.6
Koyasu, S.7
Matsui, H.8
Yamauchi-Takihara, K.9
Harada, M.10
Saito, Y.11
Ogawa, S.12
-
48
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
9716487 1:CAS:528:DyaK1cXmtFOls7c%3D
-
Heinrich PC, Behrmann I, Muller-Newen G, Schaper F, Graeve L (1998) Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J 334(Pt 2):297-314
-
(1998)
Biochem J
, vol.334
, Issue.PART 2
, pp. 297-314
-
-
Heinrich, P.C.1
Behrmann, I.2
Muller-Newen, G.3
Schaper, F.4
Graeve, L.5
-
49
-
-
38149083478
-
Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway
-
10.1074/jbc.M708568200 17993646 10.1074/jbc.M708568200 1:CAS:528:DC%2BD1cXhsFejsg%3D%3D
-
Kim JH, Kim JE, Liu HY, Cao W, Chen J (2008) Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway. J Biol Chem 283(2):708-715. doi: 10.1074/jbc.M708568200
-
(2008)
J Biol Chem
, vol.283
, Issue.2
, pp. 708-715
-
-
Kim, J.H.1
Kim, J.E.2
Liu, H.Y.3
Cao, W.4
Chen, J.5
-
50
-
-
23044468612
-
Interleukin-6 depletion selectively improves hepatic insulin action in obesity
-
10.1210/en.2004-1468 15845623 10.1210/en.2004-1468 1:CAS:528: DC%2BD2MXntVaitbc%3D
-
Klover PJ, Clementi AH, Mooney RA (2005) Interleukin-6 depletion selectively improves hepatic insulin action in obesity. Endocrinology 146(8):3417-3427. doi: 10.1210/en.2004-1468
-
(2005)
Endocrinology
, vol.146
, Issue.8
, pp. 3417-3427
-
-
Klover, P.J.1
Clementi, A.H.2
Mooney, R.A.3
-
51
-
-
0242268894
-
Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice
-
14578297 10.2337/diabetes.52.11.2784 1:CAS:528:DC%2BD3sXovVagtL8%3D
-
Klover PJ, Zimmers TA, Koniaris LG, Mooney RA (2003) Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes 52(11):2784-2789
-
(2003)
Diabetes
, vol.52
, Issue.11
, pp. 2784-2789
-
-
Klover, P.J.1
Zimmers, T.A.2
Koniaris, L.G.3
Mooney, R.A.4
-
52
-
-
33645579324
-
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production
-
10.1016/j.cmet.2006.02.009 16581004 10.1016/j.cmet.2006.02.009 1:CAS:528:DC%2BD28XktVKkur8%3D
-
Inoue H, Ogawa W, Asakawa A, Okamoto Y, Nishizawa A, Matsumoto M, Teshigawara K, Matsuki Y, Watanabe E, Hiramatsu R, Notohara K, Katayose K, Okamura H, Kahn CR, Noda T, Takeda K, Akira S, Inui A, Kasuga M (2006) Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. Cell Metab 3(4):267-275. doi: 10.1016/j.cmet.2006.02.009
-
(2006)
Cell Metab
, vol.3
, Issue.4
, pp. 267-275
-
-
Inoue, H.1
Ogawa, W.2
Asakawa, A.3
Okamoto, Y.4
Nishizawa, A.5
Matsumoto, M.6
Teshigawara, K.7
Matsuki, Y.8
Watanabe, E.9
Hiramatsu, R.10
Notohara, K.11
Katayose, K.12
Okamura, H.13
Kahn, C.R.14
Noda, T.15
Takeda, K.16
Akira, S.17
Inui, A.18
Kasuga, M.19
|