A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo

Nature Chemical Biology

Volumn 9, Issue 8, 2013, Pages 485-487

  Coelho, Pedro S ^a   Wang, Z Jane ^a   Ener, Maraia E ^a   Baril, Stefanie A ^b   Kannan, Arvind ^a   Arnold, Frances H ^a   Brustad, Eric M ^b,c  

^a California Institute of Technology   (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE; CARBENE; CARBON; CYCLOPROPANE DERIVATIVE; CYTOCHROME P450; IRON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SERINE;

ARTICLE; BACTERIAL CELL; BIOCATALYST; CHEMICAL BOND; CHEMICAL REACTION; CYCLOPROPANATION; ESCHERICHIA COLI; IN VIVO STUDY; METABOLISM; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; STEREOCHEMISTRY;

ALKENES; BIOCATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; METHANE; MUTATION; SERINE;

ESCHERICHIA COLI;

EID: 84880921220     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1278     Document Type: Article

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