Probing the molecular determinants of coenzyme selectivity in the P450 BM3 FAD/NADPH domain

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1794, Issue 8, 2009, Pages 1181-1189

  Dunford, Adrian J ^a   Girvan, Hazel M ^a   Scrutton, Nigel S ^a   Munro, Andrew W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Coenzyme selectivity; Cytochrome P450; Diflavin reductase; Flavin reduction; Thermodynamics; Transient kinetics

Indexed keywords

CYTOCHROME P450; FLAVINE ADENINE NUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONFORMATION; CONTROLLED STUDY; ENZYME KINETICS; ENZYME SPECIFICITY; PRIORITY JOURNAL; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS; THERMODYNAMICS; WILD TYPE;

AMINO ACID SEQUENCE; ARGININE; BACTERIAL PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; FLAVIN-ADENINE DINUCLEOTIDE; KINETICS; LYSINE; MOLECULAR SEQUENCE DATA; NADP; NADPH-FERRIHEMOPROTEIN REDUCTASE; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SERINE;

BACILLUS MEGATERIUM;

EID: 67349230849     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2009.03.014     Document Type: Article

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