Mitochondrial translocation of cofilin is required for allyl isothiocyanate-mediated cell death via ROCK1/PTEN/PI3K signaling pathway

Cell Communication and Signaling

Volumn 11, Issue 1, 2013, Pages

  Li, Guo Bing ^a   Cheng, Qi ^a   Liu, Lei ^a   Zhou, Ting ^a   Shan, Chang Yu ^a   Hu, Xiao Ye ^a   Zhou, Jing ^a   Liu, E Hu ^b   Li, Ping ^b   Gao, Ning ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b China Pharmaceutical University   (China)

Author keywords

Allyl isothiocyanate; Apoptosis; Cofilin; Leukemia; PI3K; ROCK1

Indexed keywords

ALLYL ISOTHIOCYANATE; COFILIN; F ACTIN; G ACTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2; PROTEIN ROCK1; REGULATOR PROTEIN; UNCLASSIFIED DRUG; ACTIN; ANTINEOPLASTIC AGENT; CFL1 PROTEIN, HUMAN; COFILIN 1; ISOTHIOCYANIC ACID DERIVATIVE; PTEN PROTEIN, HUMAN; RHO KINASE; ROCK1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER MODEL; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG MECHANISM; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR TRANSPORT; LEUKEMIA; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; ANIMAL; CELL CULTURE; CELL STRAIN HL 60; CELL STRAIN U937; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; LEUKEMIA CELL LINE; METABOLISM; MITOCHONDRION; NUDE MOUSE; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; HL 60 CELL LINE; JURKAT CELL LINE; U937 CELL LINE;

ACTINS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELLS, CULTURED; COFILIN 1; HL-60 CELLS; HUMANS; ISOTHIOCYANATES; JURKAT CELLS; LEUKEMIA; MICE; MICE, NUDE; MITOCHONDRIA; PHOSPHATIDYLINOSITOL 3-KINASES; PTEN PHOSPHOHYDROLASE; RHO-ASSOCIATED KINASES; U937 CELLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84880886618     PISSN: None     EISSN: 1478811X     Source Type: Journal    
DOI: 10.1186/1478-811X-11-50     Document Type: Article

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