The Innate Immunity Adaptor SARM Translocates to the Nucleus to Stabilize Lamins and Prevent DNA Fragmentation in Response to Pro-Apoptotic Signaling

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Sethman, Chad R ^a,b   Hawiger, Jacek ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Waynesburg University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; DNA; LAMIN; LAMIN A; LAMIN C; STERILE ALPHA AND ARMADILLO MOTIF CONTAINING PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL STRAIN HEK293; CONTROLLED STUDY; DNA FRAGMENTATION; EMBRYO; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; NUCLEAR LAMINA; PROTEIN DEGRADATION; PROTEIN STABILITY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

APOPTOSIS; ARMADILLO DOMAIN PROTEINS; CASPASE 6; CELL LINE; CELL NUCLEUS; CYTOSKELETAL PROTEINS; DNA FRAGMENTATION; GENE EXPRESSION; GENE ORDER; GENETIC VECTORS; HUMANS; IMMUNITY, INNATE; LAMINS; PROTEIN STABILITY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84880835807     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070994     Document Type: Article

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