메뉴 건너뛰기




Volumn 24, Issue 4, 2012, Pages 488-493

Chronic inflammation and aging: DNA damage tips the balance

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; AGING; ANTIGEN SPECIFICITY; CELL AGING; CELL DIFFERENTIATION; CELL LINEAGE; CELL RENEWAL; CHRONIC INFLAMMATION; DNA DAMAGE; EFFECTOR CELL; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOREGULATION; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE SUBPOPULATION; LYMPHOID PROGENITOR CELL; MULTIPOTENT STEM CELL; MYELOID PROGENITOR CELL; REVIEW; SENESCENCE;

EID: 84865304528     PISSN: 09527915     EISSN: 18790372     Source Type: Journal    
DOI: 10.1016/j.coi.2012.04.003     Document Type: Review
Times cited : (77)

References (48)
  • 1
    • 84862776821 scopus 로고    scopus 로고
    • The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines
    • McElhaney J.E., Zhou X., Talbot H.K., Soethout E., Bleackley R.C., Granville D.J., Pawelec G. The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines. Vaccine 2012, 30:2060-2067.
    • (2012) Vaccine , vol.30 , pp. 2060-2067
    • McElhaney, J.E.1    Zhou, X.2    Talbot, H.K.3    Soethout, E.4    Bleackley, R.C.5    Granville, D.J.6    Pawelec, G.7
  • 2
    • 33847396631 scopus 로고    scopus 로고
    • Avian influenza A (H5N1) age distribution in humans
    • Smallman-Raynor M., Cliff A.D. Avian influenza A (H5N1) age distribution in humans. Emerg Infect Dis 2007, 13:510-512.
    • (2007) Emerg Infect Dis , vol.13 , pp. 510-512
    • Smallman-Raynor, M.1    Cliff, A.D.2
  • 7
    • 79951899662 scopus 로고    scopus 로고
    • Seropositivity to cytomegalovirus, inflammation, all-cause and cardiovascular disease-related mortality in the United States
    • Simanek A.M., Dowd J.B., Pawelec G., Melzer D., Dutta A., Aiello A.E. Seropositivity to cytomegalovirus, inflammation, all-cause and cardiovascular disease-related mortality in the United States. PLoS ONE 2011, 6:e16103.
    • (2011) PLoS ONE , vol.6
    • Simanek, A.M.1    Dowd, J.B.2    Pawelec, G.3    Melzer, D.4    Dutta, A.5    Aiello, A.E.6
  • 10
  • 11
    • 47049099198 scopus 로고    scopus 로고
    • A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells
    • Cho R.H., Sieburg H.B., Muller-Sieburg C.E. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood 2008, 111:5553-5561.
    • (2008) Blood , vol.111 , pp. 5553-5561
    • Cho, R.H.1    Sieburg, H.B.2    Muller-Sieburg, C.E.3
  • 12
    • 84860343741 scopus 로고    scopus 로고
    • Stem cell heterogeneity: implications for aging and regenerative medicine
    • Muller-Sieburg C., Sieburg H.B., Bernitz J.M., Cattarossi G. Stem cell heterogeneity: implications for aging and regenerative medicine. Blood 2012, 119:3900-3907.
    • (2012) Blood , vol.119 , pp. 3900-3907
    • Muller-Sieburg, C.1    Sieburg, H.B.2    Bernitz, J.M.3    Cattarossi, G.4
  • 14
    • 77950418688 scopus 로고    scopus 로고
    • Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
    • Beerman I., Bhattacharya D., Zandi S., Sigvardsson M., Weissman I.L., Bryder D., Rossi D.J. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci USA 2010, 107:5465-5470.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5465-5470
    • Beerman, I.1    Bhattacharya, D.2    Zandi, S.3    Sigvardsson, M.4    Weissman, I.L.5    Bryder, D.6    Rossi, D.J.7
  • 17
    • 84857883769 scopus 로고    scopus 로고
    • DNA-damage-induced differentiation in hematopoietic stem cells
    • Mandal P.K., Rossi D.J. DNA-damage-induced differentiation in hematopoietic stem cells. Cell 2012, 148:847-848.
    • (2012) Cell , vol.148 , pp. 847-848
    • Mandal, P.K.1    Rossi, D.J.2
  • 22
    • 84858864678 scopus 로고    scopus 로고
    • Resolve, revise, and relax: the 3 Rs of B cell repertoire adjustment
    • Scholz J.L., Cancro M.P. Resolve, revise, and relax: the 3 Rs of B cell repertoire adjustment. Immunol Lett 2012, 143:2-8.
    • (2012) Immunol Lett , vol.143 , pp. 2-8
    • Scholz, J.L.1    Cancro, M.P.2
  • 23
    • 84855862448 scopus 로고    scopus 로고
    • Persistent degenerative changes in thymic organ function revealed by an inducible model of organ regrowth
    • Griffith A.V., Fallahi M., Venables T., Petrie H.T. Persistent degenerative changes in thymic organ function revealed by an inducible model of organ regrowth. Aging Cell 2012, 11:169-177.
    • (2012) Aging Cell , vol.11 , pp. 169-177
    • Griffith, A.V.1    Fallahi, M.2    Venables, T.3    Petrie, H.T.4
  • 25
    • 80051569441 scopus 로고    scopus 로고
    • A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
    • Hao Y., O'Neill P., Naradikian M.S., Scholz J.L., Cancro M.P. A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. Blood 2011, 118:1294-1304.
    • (2011) Blood , vol.118 , pp. 1294-1304
    • Hao, Y.1    O'Neill, P.2    Naradikian, M.S.3    Scholz, J.L.4    Cancro, M.P.5
  • 27
    • 0035147101 scopus 로고    scopus 로고
    • CD4+, CD28- T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems
    • Warrington K.J., Takemura S., Goronzy J.J., Weyand C.M. CD4+, CD28- T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems. Arthritis Rheum 2001, 44:13-20.
    • (2001) Arthritis Rheum , vol.44 , pp. 13-20
    • Warrington, K.J.1    Takemura, S.2    Goronzy, J.J.3    Weyand, C.M.4
  • 29
    • 67449135849 scopus 로고    scopus 로고
    • Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion
    • Bucks C.M., Norton J.A., Boesteanu A.C., Mueller Y.M., Katsikis P.D. Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion. J Immunol 2009, 182:6697-6708.
    • (2009) J Immunol , vol.182 , pp. 6697-6708
    • Bucks, C.M.1    Norton, J.A.2    Boesteanu, A.C.3    Mueller, Y.M.4    Katsikis, P.D.5
  • 31
    • 84860887914 scopus 로고    scopus 로고
    • Aged regulatory T cells protect from autoimmune inflammation despite reduced STAT3 activation and decreased constraint of IL-17 producing T cells
    • PMID: 22372596
    • Sun L., Hurez V., Thibodeaux S.R., Kious M.J., Liu A., Lin P., Murthy K., Pandeswara S., Shin T., Curiel T.J. Aged regulatory T cells protect from autoimmune inflammation despite reduced STAT3 activation and decreased constraint of IL-17 producing T cells. Aging Cell 2012, PMID: 22372596. 10.1111/j.1474-9726.2012.00812.x.
    • (2012) Aging Cell
    • Sun, L.1    Hurez, V.2    Thibodeaux, S.R.3    Kious, M.J.4    Liu, A.5    Lin, P.6    Murthy, K.7    Pandeswara, S.8    Shin, T.9    Curiel, T.J.10
  • 32
    • 79952115866 scopus 로고    scopus 로고
    • DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis
    • Shao L., Goronzy J.J., Weyand C.M. DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis. EMBO Mol Med 2010, 2:415-427.
    • (2010) EMBO Mol Med , vol.2 , pp. 415-427
    • Shao, L.1    Goronzy, J.J.2    Weyand, C.M.3
  • 33
  • 36
    • 77952572147 scopus 로고    scopus 로고
    • DNA-PKcs controls an endosomal signaling pathway for a proinflammatory response by natural killer cells
    • Rajagopalan S., Moyle M.W., Joosten I., Long E.O. DNA-PKcs controls an endosomal signaling pathway for a proinflammatory response by natural killer cells. Sci Signal 2010, 3:ra14.
    • (2010) Sci Signal , vol.3
    • Rajagopalan, S.1    Moyle, M.W.2    Joosten, I.3    Long, E.O.4
  • 37
    • 84859864546 scopus 로고    scopus 로고
    • Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: The Vitality 90+ Study
    • Jylhava J., Jylha M., Lehtimaki T., Hervonen A., Hurme M. Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: The Vitality 90+ Study. Exp Gerontol 2012, 47:372-378.
    • (2012) Exp Gerontol , vol.47 , pp. 372-378
    • Jylhava, J.1    Jylha, M.2    Lehtimaki, T.3    Hervonen, A.4    Hurme, M.5
  • 40
    • 53449092909 scopus 로고    scopus 로고
    • Vessel-specific Toll-like receptor profiles in human medium and large arteries
    • Pryshchep O., Ma-Krupa W., Younge B.R., Goronzy J.J., Weyand C.M. Vessel-specific Toll-like receptor profiles in human medium and large arteries. Circulation 2008, 118:1276-1284.
    • (2008) Circulation , vol.118 , pp. 1276-1284
    • Pryshchep, O.1    Ma-Krupa, W.2    Younge, B.R.3    Goronzy, J.J.4    Weyand, C.M.5
  • 42
    • 79951912532 scopus 로고    scopus 로고
    • Four faces of cellular senescence
    • Rodier F., Campisi J. Four faces of cellular senescence. J Cell Biol 2011, 192:547-556.
    • (2011) J Cell Biol , vol.192 , pp. 547-556
    • Rodier, F.1    Campisi, J.2
  • 43
    • 79955017452 scopus 로고    scopus 로고
    • P38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
    • Freund A., Patil C.K., Campisi J. p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype. EMBO J 2011, 30:1536-1548.
    • (2011) EMBO J , vol.30 , pp. 1536-1548
    • Freund, A.1    Patil, C.K.2    Campisi, J.3
  • 44
    • 80051709190 scopus 로고    scopus 로고
    • Inflammation and p53: a tale of two stresses
    • Gudkov A.V., Gurova K.V., Komarova E.A. Inflammation and p53: a tale of two stresses. Genes Cancer 2011, 2:503-516.
    • (2011) Genes Cancer , vol.2 , pp. 503-516
    • Gudkov, A.V.1    Gurova, K.V.2    Komarova, E.A.3
  • 46
    • 73349099041 scopus 로고    scopus 로고
    • Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen
    • Maroof A., Beattie L., Kirby A., Coles M., Kaye P.M. Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen. J Immunol 2009, 183:7095-7103.
    • (2009) J Immunol , vol.183 , pp. 7095-7103
    • Maroof, A.1    Beattie, L.2    Kirby, A.3    Coles, M.4    Kaye, P.M.5
  • 47
    • 23244454963 scopus 로고    scopus 로고
    • Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells
    • Nogai A., Siffrin V., Bonhagen K., Pfueller C.F., Hohnstein T., Volkmer-Engert R., Bruck W., Stadelmann C., Kamradt T. Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells. J Immunol 2005, 175:959-966.
    • (2005) J Immunol , vol.175 , pp. 959-966
    • Nogai, A.1    Siffrin, V.2    Bonhagen, K.3    Pfueller, C.F.4    Hohnstein, T.5    Volkmer-Engert, R.6    Bruck, W.7    Stadelmann, C.8    Kamradt, T.9
  • 48
    • 79251548576 scopus 로고    scopus 로고
    • T cell-intrinsic factors contribute to the differential ability of CD8+ T cells to rapidly secrete IFN-gamma in the absence of antigen
    • Bou Ghanem E.N., Nelson C.C., D'Orazio S.E. T cell-intrinsic factors contribute to the differential ability of CD8+ T cells to rapidly secrete IFN-gamma in the absence of antigen. J Immunol 2011, 186:1703-1712.
    • (2011) J Immunol , vol.186 , pp. 1703-1712
    • Bou Ghanem, E.N.1    Nelson, C.C.2    D'Orazio, S.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.