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Volumn 61, Issue 9, 2013, Pages 1556-1569

GFAP expression and social deficits in transgenic mice overexpressing human sAPPα

Author keywords

Astrogliosis; Autism; Behavior; IL 6; Notch; SAPP

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN ALPHA; BETA TUBULIN; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 6; NOTCH1 RECEPTOR; UNCLASSIFIED DRUG;

EID: 84880816899     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22544     Document Type: Article
Times cited : (23)

References (71)
  • 1
    • 0027248051 scopus 로고
    • Glial fibrillary acidic protein in the cerebrospinal fluid of children with autism and other neuropsychiatric disorders
    • Ahlsen G, Rosengren L, Belfrage M, Palm A, Haglid K, Hamberger A, Gillberg C. 1993. Glial fibrillary acidic protein in the cerebrospinal fluid of children with autism and other neuropsychiatric disorders. Biol Psychiatry 33:734-743.
    • (1993) Biol Psychiatry , vol.33 , pp. 734-743
    • Ahlsen, G.1    Rosengren, L.2    Belfrage, M.3    Palm, A.4    Haglid, K.5    Hamberger, A.6    Gillberg, C.7
  • 3
    • 84870469320 scopus 로고    scopus 로고
    • APA. ., 4th ed, Text Revision (DSM-IV-TR). Arlington, VA: American Psychiatric Publishing, Inc.
    • APA. 2000. Diagnostic and Statistical Manual of Mental Disorders, 4th ed, Text Revision (DSM-IV-TR). Arlington, VA: American Psychiatric Publishing, Inc.
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 5
    • 84863242859 scopus 로고    scopus 로고
    • Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-alpha: Implications for autism
    • Bailey AR, Hou H, Obregon DF, Tian J, Zhu Y, Zou Q, Nikolic WV, Bengtson M, Mori T, Murphy T and others. 2012. Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-alpha: Implications for autism. FASEB J 26:1040-1051.
    • (2012) FASEB J , vol.26 , pp. 1040-1051
    • Bailey, A.R.1    Hou, H.2    Obregon, D.F.3    Tian, J.4    Zhu, Y.5    Zou, Q.6    Nikolic, W.V.7    Bengtson, M.8    Mori, T.9    Murphy, T.10
  • 6
    • 84862697779 scopus 로고    scopus 로고
    • Secreted amyloid precursor proteins promote proliferation and glial differentiation of adult hippocampal neural progenitor cells
    • Baratchi S, Evans J, Tate WP, Abraham WC, Connor B. 2012. Secreted amyloid precursor proteins promote proliferation and glial differentiation of adult hippocampal neural progenitor cells. Hippocampus 22:1517-1527.
    • (2012) Hippocampus , vol.22 , pp. 1517-1527
    • Baratchi, S.1    Evans, J.2    Tate, W.P.3    Abraham, W.C.4    Connor, B.5
  • 7
    • 0035146889 scopus 로고    scopus 로고
    • Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function
    • Barger SW, Basile AS. 2001. Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. J Neurochem 76:846-854.
    • (2001) J Neurochem , vol.76 , pp. 846-854
    • Barger, S.W.1    Basile, A.S.2
  • 8
    • 0028912956 scopus 로고
    • Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor
    • Barger SW, Fiscus RR, Ruth P, Hofmann F, Mattson MP. 1995. Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor. J Neurochem 64:2087-2096.
    • (1995) J Neurochem , vol.64 , pp. 2087-2096
    • Barger, S.W.1    Fiscus, R.R.2    Ruth, P.3    Hofmann, F.4    Mattson, M.P.5
  • 9
    • 0030610645 scopus 로고    scopus 로고
    • Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E
    • Barger SW, Harmon AD. 1997. Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 388:878-881.
    • (1997) Nature , vol.388 , pp. 878-881
    • Barger, S.W.1    Harmon, A.D.2
  • 10
    • 14644395605 scopus 로고    scopus 로고
    • Neuroanatomic observations of the brain in autism: A review and future directions
    • Bauman ML, Kemper TL. 2005. Neuroanatomic observations of the brain in autism: A review and future directions. Int J Dev Neurosci 23:183-187.
    • (2005) Int J Dev Neurosci , vol.23 , pp. 183-187
    • Bauman, M.L.1    Kemper, T.L.2
  • 11
    • 55049097325 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor-mediated signaling regulates neuronal versus glial differentiation of retinal stem cells/progenitors by concentration-dependent recruitment of mitogen-activated protein kinase and Janus kinase-signal transducer and activator of transcription pathways in conjunction with Notch signaling
    • Bhattacharya S, Das AV, Mallya KB, Ahmad I. 2008. Ciliary neurotrophic factor-mediated signaling regulates neuronal versus glial differentiation of retinal stem cells/progenitors by concentration-dependent recruitment of mitogen-activated protein kinase and Janus kinase-signal transducer and activator of transcription pathways in conjunction with Notch signaling. Stem Cells 26:2611-2624.
    • (2008) Stem Cells , vol.26 , pp. 2611-2624
    • Bhattacharya, S.1    Das, A.V.2    Mallya, K.B.3    Ahmad, I.4
  • 12
    • 0035668329 scopus 로고    scopus 로고
    • Anterior insular cortex: Linking intestinal pathology and brain function in autism-spectrum subgroups
    • Binstock T. 2001. Anterior insular cortex: Linking intestinal pathology and brain function in autism-spectrum subgroups. Med Hypotheses 57:714-717.
    • (2001) Med Hypotheses , vol.57 , pp. 714-717
    • Binstock, T.1
  • 14
    • 33748170724 scopus 로고    scopus 로고
    • Neuropathological and genetic findings in autism: The significance of a putative minicolumnopathy
    • Casanova MF. 2006. Neuropathological and genetic findings in autism: The significance of a putative minicolumnopathy. Neuroscientist 12:435-441.
    • (2006) Neuroscientist , vol.12 , pp. 435-441
    • Casanova, M.F.1
  • 17
    • 13444250843 scopus 로고    scopus 로고
    • Designing mouse behavioral tasks relevant to autistic-like behaviors
    • Crawley JN. 2004. Designing mouse behavioral tasks relevant to autistic-like behaviors. Ment Retard Dev Disabil Res Rev 10:248-258.
    • (2004) Ment Retard Dev Disabil Res Rev , vol.10 , pp. 248-258
    • Crawley, J.N.1
  • 18
    • 0037014577 scopus 로고    scopus 로고
    • Evidence for binding of the ectodomain of amyloid precursor protein 695 and activated high molecular weight kininogen
    • Das A, Smalheiser NR, Markaryan A, Kaplan A. 2002. Evidence for binding of the ectodomain of amyloid precursor protein 695 and activated high molecular weight kininogen. Biochim Biophys Acta 1571:225-238.
    • (2002) Biochim Biophys Acta , vol.1571 , pp. 225-238
    • Das, A.1    Smalheiser, N.R.2    Markaryan, A.3    Kaplan, A.4
  • 19
    • 0034049944 scopus 로고    scopus 로고
    • Proteolytic processing and cell biological functions of the amyloid precursor protein
    • De Strooper B, Annaert W. 2000. Proteolytic processing and cell biological functions of the amyloid precursor protein. J Cell Sci 113:1857-1870.
    • (2000) J Cell Sci , vol.113 , pp. 1857-1870
    • De Strooper, B.1    Annaert, W.2
  • 20
    • 70349838218 scopus 로고    scopus 로고
    • Cytokines and CNS development
    • Deverman BE, Patterson PH. 2009. Cytokines and CNS development. Neuron 64:61-78.
    • (2009) Neuron , vol.64 , pp. 61-78
    • Deverman, B.E.1    Patterson, P.H.2
  • 21
    • 0037114956 scopus 로고    scopus 로고
    • Telomerase mediates the cell survival-promoting actions of brain-derived neurotrophic factor and secreted amyloid precursor protein in developing hippocampal neurons
    • Fu W, Lu C, Mattson MP. 2002. Telomerase mediates the cell survival-promoting actions of brain-derived neurotrophic factor and secreted amyloid precursor protein in developing hippocampal neurons. J Neurosci 22:10710-10719.
    • (2002) J Neurosci , vol.22 , pp. 10710-10719
    • Fu, W.1    Lu, C.2    Mattson, M.P.3
  • 22
    • 0030068094 scopus 로고    scopus 로고
    • Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein
    • Furukawa K, Barger SW, Blalock EM, Mattson MP. 1996. Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein. Nature 379:74-78.
    • (1996) Nature , vol.379 , pp. 74-78
    • Furukawa, K.1    Barger, S.W.2    Blalock, E.M.3    Mattson, M.P.4
  • 23
    • 0031905682 scopus 로고    scopus 로고
    • Secreted amyloid precursor protein alpha selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic GMP
    • Furukawa K, Mattson MP. 1998. Secreted amyloid precursor protein alpha selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic GMP. Neuroscience 83:429-438.
    • (1998) Neuroscience , vol.83 , pp. 429-438
    • Furukawa, K.1    Mattson, M.P.2
  • 24
    • 0036304110 scopus 로고    scopus 로고
    • The role of notch in promoting glial and neural stem cell fates
    • Gaiano N, Fishell G. 2002. The role of notch in promoting glial and neural stem cell fates. Annu Rev Neurosci 25:471-490.
    • (2002) Annu Rev Neurosci , vol.25 , pp. 471-490
    • Gaiano, N.1    Fishell, G.2
  • 25
    • 0033758237 scopus 로고    scopus 로고
    • Autism and Asperger syndrome: Coexistence with other clinical disorders
    • Gillberg C, Billstedt E. 2000. Autism and Asperger syndrome: Coexistence with other clinical disorders. Acta Psychiatr Scand 102:321-330.
    • (2000) Acta Psychiatr Scand , vol.102 , pp. 321-330
    • Gillberg, C.1    Billstedt, E.2
  • 28
    • 0025033996 scopus 로고
    • Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease
    • Jorgensen OS, Brooksbank BW, Balazs R. 1990. Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease. J Neurol Sci 98:63-79.
    • (1990) J Neurol Sci , vol.98 , pp. 63-79
    • Jorgensen, O.S.1    Brooksbank, B.W.2    Balazs, R.3
  • 29
    • 77952560331 scopus 로고    scopus 로고
    • Involvement of gp130-associated cytokine signaling in Muller cell activation following optic nerve lesion
    • Kirsch M, Trautmann N, Ernst M, Hofmann HD. 2010. Involvement of gp130-associated cytokine signaling in Muller cell activation following optic nerve lesion. Glia 58:768-779.
    • (2010) Glia , vol.58 , pp. 768-779
    • Kirsch, M.1    Trautmann, N.2    Ernst, M.3    Hofmann, H.D.4
  • 30
    • 0030592750 scopus 로고    scopus 로고
    • Cell surface APP751 forms complexes with protease nexin 2 ligands and is internalized via the low density lipoprotein receptor-related protein (LRP)
    • Knauer MF, Orlando RA, Glabe CG. 1996. Cell surface APP751 forms complexes with protease nexin 2 ligands and is internalized via the low density lipoprotein receptor-related protein (LRP). Brain Res 740:6-14.
    • (1996) Brain Res , vol.740 , pp. 6-14
    • Knauer, M.F.1    Orlando, R.A.2    Glabe, C.G.3
  • 31
    • 0029128232 scopus 로고
    • LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation
    • Kounnas MZ, Moir RD, Rebeck GW, Bush AI, Argraves WS, Tanzi RE, Hyman BT, Strickland DK. 1995. LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation. Cell 82:331-340.
    • (1995) Cell , vol.82 , pp. 331-340
    • Kounnas, M.Z.1    Moir, R.D.2    Rebeck, G.W.3    Bush, A.I.4    Argraves, W.S.5    Tanzi, R.E.6    Hyman, B.T.7    Strickland, D.K.8
  • 34
    • 33646048760 scopus 로고    scopus 로고
    • Amyloid precursor protein is involved in staurosporine induced glial differentiation of neural progenitor cells
    • Kwak YD, Choumkina E, Sugaya K. 2006b. Amyloid precursor protein is involved in staurosporine induced glial differentiation of neural progenitor cells. Biochem Biophys Res Commun 344:431-437.
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 431-437
    • Kwak, Y.D.1    Choumkina, E.2    Sugaya, K.3
  • 35
    • 78049299534 scopus 로고    scopus 로고
    • Amyloid-beta precursor protein induces glial differentiation of neural progenitor cells by activation of the IL-6/gp130 signaling pathway
    • Kwak YD, Dantuma E, Merchant S, Bushnev S, Sugaya K. 2010. Amyloid-beta precursor protein induces glial differentiation of neural progenitor cells by activation of the IL-6/gp130 signaling pathway. Neurotox Res 18:328-338.
    • (2010) Neurotox Res , vol.18 , pp. 328-338
    • Kwak, Y.D.1    Dantuma, E.2    Merchant, S.3    Bushnev, S.4    Sugaya, K.5
  • 36
    • 78649759353 scopus 로고    scopus 로고
    • Involvement of notch signaling pathway in amyloid precursor protein induced glial differentiation
    • Kwak YD, Marutle A, Dantuma E, Merchant S, Bushnev S, Sugaya K. 2011. Involvement of notch signaling pathway in amyloid precursor protein induced glial differentiation. Eur J Pharmacol 650:18-27.
    • (2011) Eur J Pharmacol , vol.650 , pp. 18-27
    • Kwak, Y.D.1    Marutle, A.2    Dantuma, E.3    Merchant, S.4    Bushnev, S.5    Sugaya, K.6
  • 37
    • 17844410115 scopus 로고    scopus 로고
    • Notch signaling, brain development, and human disease
    • Lasky JL, Wu H. 2005. Notch signaling, brain development, and human disease. Pediatr Res 57:104R-109R.
    • (2005) Pediatr Res , vol.57
    • Lasky, J.L.1    Wu, H.2
  • 38
    • 25144495490 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein is elevated in superior frontal, parietal and cerebellar cortices of autistic subjects
    • Laurence JA, Fatemi SH. 2005. Glial fibrillary acidic protein is elevated in superior frontal, parietal and cerebellar cortices of autistic subjects. Cerebellum 4:206-210.
    • (2005) Cerebellum , vol.4 , pp. 206-210
    • Laurence, J.A.1    Fatemi, S.H.2
  • 39
    • 0033993523 scopus 로고    scopus 로고
    • Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression
    • Li Y, Liu L, Kang J, Sheng JG, Barger SW, Mrak RE, Griffin WS. 2000. Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression. J Neurosci 20:149-155.
    • (2000) J Neurosci , vol.20 , pp. 149-155
    • Li, Y.1    Liu, L.2    Kang, J.3    Sheng, J.G.4    Barger, S.W.5    Mrak, R.E.6    Griffin, W.S.7
  • 40
    • 0035282739 scopus 로고    scopus 로고
    • Characterization of the neurotrophic interaction between nerve growth factor and secreted alpha-amyloid precursor protein
    • Luo JJ, Wallace MS, Hawver DB, Kusiak JW, Wallace WC. 2001. Characterization of the neurotrophic interaction between nerve growth factor and secreted alpha-amyloid precursor protein. J Neurosci Res 63:410-420.
    • (2001) J Neurosci Res , vol.63 , pp. 410-420
    • Luo, J.J.1    Wallace, M.S.2    Hawver, D.B.3    Kusiak, J.W.4    Wallace, W.C.5
  • 42
    • 0345104338 scopus 로고    scopus 로고
    • Role of interleukin-6 and soluble IL-6 receptor in region-specific induction of astrocytic differentiation and neurotrophin expression
    • Marz P, Heese K, Dimitriades-Schmutz B, Rose-John S, Otten U. 1999. Role of interleukin-6 and soluble IL-6 receptor in region-specific induction of astrocytic differentiation and neurotrophin expression. Glia 26:191-200.
    • (1999) Glia , vol.26 , pp. 191-200
    • Marz, P.1    Heese, K.2    Dimitriades-Schmutz, B.3    Rose-John, S.4    Otten, U.5
  • 43
    • 0026743208 scopus 로고
    • Amyloid precursor protein is localized in growing neurites of neonatal rat brain
    • Masliah E, Mallory M, Ge N, Saitoh T. 1992. Amyloid precursor protein is localized in growing neurites of neonatal rat brain. Brain Res 593:323-328.
    • (1992) Brain Res , vol.593 , pp. 323-328
    • Masliah, E.1    Mallory, M.2    Ge, N.3    Saitoh, T.4
  • 44
    • 0030779677 scopus 로고    scopus 로고
    • Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives
    • Mattson MP. 1997. Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives. Physiol Rev 77:1081-1132.
    • (1997) Physiol Rev , vol.77 , pp. 1081-1132
    • Mattson, M.P.1
  • 46
    • 0027478347 scopus 로고
    • Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein
    • Mattson MP, Cheng B, Culwell AR, Esch FS, Lieberburg I, Rydel RE. 1993b. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein. Neuron 10:243-254.
    • (1993) Neuron , vol.10 , pp. 243-254
    • Mattson, M.P.1    Cheng, B.2    Culwell, A.R.3    Esch, F.S.4    Lieberburg, I.5    Rydel, R.E.6
  • 47
    • 0026663993 scopus 로고
    • The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth
    • Milward EA, Papadopoulos R, Fuller SJ, Moir RD, Small D, Beyreuther K, Masters CL. 1992. The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron 9:129-137.
    • (1992) Neuron , vol.9 , pp. 129-137
    • Milward, E.A.1    Papadopoulos, R.2    Fuller, S.J.3    Moir, R.D.4    Small, D.5    Beyreuther, K.6    Masters, C.L.7
  • 48
    • 0029924264 scopus 로고    scopus 로고
    • Neurotrophic and neuroprotective effects of hAPP in transgenic mice
    • Mucke L, Abraham CR, Masliah E. 1996. Neurotrophic and neuroprotective effects of hAPP in transgenic mice. Ann N Y Acad Sci 777:82-88.
    • (1996) Ann N Y Acad Sci , vol.777 , pp. 82-88
    • Mucke, L.1    Abraham, C.R.2    Masliah, E.3
  • 49
    • 34347335705 scopus 로고    scopus 로고
    • Cross talk between notch and growth factor/cytokine signaling pathways in neural stem cells
    • Nagao M, Sugimori M, Nakafuku M. 2007. Cross talk between notch and growth factor/cytokine signaling pathways in neural stem cells. Mol Cell Biol 27:3982-3994.
    • (2007) Mol Cell Biol , vol.27 , pp. 3982-3994
    • Nagao, M.1    Sugimori, M.2    Nakafuku, M.3
  • 50
    • 79959949333 scopus 로고    scopus 로고
    • Roles of glial cells in neural circuit formation: insights from research in insects
    • Oland LA, Tolbert LP. 2011. Roles of glial cells in neural circuit formation: insights from research in insects. Glia 59:1273-1295.
    • (2011) Glia , vol.59 , pp. 1273-1295
    • Oland, L.A.1    Tolbert, L.P.2
  • 52
    • 79959407483 scopus 로고    scopus 로고
    • Increased secreted amyloid precursor protein-alpha (sAPPalpha) in severe autism: Proposal of a specific, anabolic pathway and putative biomarker
    • Ray B, Long JM, Sokol DK, Lahiri DK. 2011. Increased secreted amyloid precursor protein-alpha (sAPPalpha) in severe autism: Proposal of a specific, anabolic pathway and putative biomarker. PLoS ONE 6:e20405.
    • (2011) PLoS ONE , vol.6
    • Ray, B.1    Long, J.M.2    Sokol, D.K.3    Lahiri, D.K.4
  • 53
    • 13444258044 scopus 로고    scopus 로고
    • Interaction and imitation deficits from infancy to 4 years of age in children with autism: A pilot study based on videotapes
    • Receveur C, Lenoir P, Desombre H, Roux S, Barthelemy C, Malvy J. 2005. Interaction and imitation deficits from infancy to 4 years of age in children with autism: A pilot study based on videotapes. Autism 9:69-82.
    • (2005) Autism , vol.9 , pp. 69-82
    • Receveur, C.1    Lenoir, P.2    Desombre, H.3    Roux, S.4    Barthelemy, C.5    Malvy, J.6
  • 54
    • 0028071334 scopus 로고
    • Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor
    • Roch JM, Masliah E, Roch-Levecq AC, Sundsmo MP, Otero DA, Veinbergs I, Saitoh T. 1994. Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor. Proc Natl Acad Sci USA 91:7450-7454.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7450-7454
    • Roch, J.M.1    Masliah, E.2    Roch-Levecq, A.C.3    Sundsmo, M.P.4    Otero, D.A.5    Veinbergs, I.6    Saitoh, T.7
  • 56
    • 0033955447 scopus 로고    scopus 로고
    • Pathological and neuropathological findings in two males with fragile-X syndrome
    • Sabaratnam M. 2000. Pathological and neuropathological findings in two males with fragile-X syndrome. J Intellect Disabil Res 44:81-85.
    • (2000) J Intellect Disabil Res , vol.44 , pp. 81-85
    • Sabaratnam, M.1
  • 57
    • 0035903204 scopus 로고    scopus 로고
    • Secreted forms of the amyloid-beta precursor protein are ligands for the class A scavenger receptor
    • Santiago-Garcia J, Mas-Oliva J, Innerarity TL, Pitas RE. 2001. Secreted forms of the amyloid-beta precursor protein are ligands for the class A scavenger receptor. J Biol Chem 276:30655-30661.
    • (2001) J Biol Chem , vol.276 , pp. 30655-30661
    • Santiago-Garcia, J.1    Mas-Oliva, J.2    Innerarity, T.L.3    Pitas, R.E.4
  • 58
    • 0001067847 scopus 로고
    • Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues
    • Selkoe DJ, Podlisny MB, Joachim CL, Vickers EA, Lee G, Fritz LC, Oltersdorf T. 1988. Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues. Proc Natl Acad Sci USA 85:7341-7345.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7341-7345
    • Selkoe, D.J.1    Podlisny, M.B.2    Joachim, C.L.3    Vickers, E.A.4    Lee, G.5    Fritz, L.C.6    Oltersdorf, T.7
  • 61
    • 33746049824 scopus 로고    scopus 로고
    • High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression
    • Sokol DK, Chen D, Farlow MR, Dunn DW, Maloney B, Zimmer JA, Lahiri DK. 2006. High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression. J Child Neurol 21:444-449.
    • (2006) J Child Neurol , vol.21 , pp. 444-449
    • Sokol, D.K.1    Chen, D.2    Farlow, M.R.3    Dunn, D.W.4    Maloney, B.5    Zimmer, J.A.6    Lahiri, D.K.7
  • 62
    • 84860338445 scopus 로고    scopus 로고
    • The complement system: an unexpected role in synaptic pruning during development and disease
    • Stephan AH, Barres BA, Stevens B. 2012. The complement system: an unexpected role in synaptic pruning during development and disease. Annu Rev Neurosci 35:369-389.
    • (2012) Annu Rev Neurosci , vol.35 , pp. 369-389
    • Stephan, A.H.1    Barres, B.A.2    Stevens, B.3
  • 64
    • 40449103490 scopus 로고    scopus 로고
    • Mechanism of glial differentiation of neural progenitor cells by amyloid precursor protein
    • Sugaya K. 2008. Mechanism of glial differentiation of neural progenitor cells by amyloid precursor protein. Neurodegener Dis 5:170-172.
    • (2008) Neurodegener Dis , vol.5 , pp. 170-172
    • Sugaya, K.1
  • 66
    • 23944450567 scopus 로고    scopus 로고
    • Role of IL-6 in the neural stem cell differentiation
    • Taga T, Fukuda S. 2005. Role of IL-6 in the neural stem cell differentiation. Clin Rev Allergy Immunol 28:249-256.
    • (2005) Clin Rev Allergy Immunol , vol.28 , pp. 249-256
    • Taga, T.1    Fukuda, S.2
  • 67
    • 0042634362 scopus 로고    scopus 로고
    • Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
    • Turner PR, O'Connor K, Tate WP, Abraham WC. 2003. Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory. Prog Neurobiol 70:1-32.
    • (2003) Prog Neurobiol , vol.70 , pp. 1-32
    • Turner, P.R.1    O'Connor, K.2    Tate, W.P.3    Abraham, W.C.4
  • 68
  • 69
    • 0033678987 scopus 로고    scopus 로고
    • Up a notch: Instructing gliogenesis
    • Wang S, Barres BA. 2000. Up a notch: Instructing gliogenesis. Neuron 27:197-200.
    • (2000) Neuron , vol.27 , pp. 197-200
    • Wang, S.1    Barres, B.A.2
  • 70
    • 0036935170 scopus 로고    scopus 로고
    • Induction of STAT3 signaling in activated astrocytes and sprouting septal neurons following entorhinal cortex lesion in adult rats
    • Xia XG, Hofmann HD, Deller T, Kirsch M. 2002. Induction of STAT3 signaling in activated astrocytes and sprouting septal neurons following entorhinal cortex lesion in adult rats. Mol Cell Neurosci 21:379-392.
    • (2002) Mol Cell Neurosci , vol.21 , pp. 379-392
    • Xia, X.G.1    Hofmann, H.D.2    Deller, T.3    Kirsch, M.4


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