Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-α: Implications for autism

FASEB Journal

Volumn 26, Issue 3, 2012, Pages 1040-1051

  Bailey, Antoinette R ^a   Hou, Huayan ^a   Obregon, Demian F ^a   Tian, Jun ^a   Zhu, Yuyan ^a   Zou, Qiang ^a   Nikolic, William V ^c   Bengtson, Michael ^a   Mori, Takashi ^d   Murphy, Tanya ^b   Tan, Jun ^a  

^a Silver Child Development Center   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c UNIVERSITY OF KRAGUJEVAC   (Serbia)

^d SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

sAPP ; T cells; Transgenic mice

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN ALPHA; CASPASE 3; GAMMA INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; NOTCH1 RECEPTOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE ZAP 70; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME REPRESSION; GENE OVEREXPRESSION; HUMAN; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; LYMPHOCYTE SUBPOPULATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SPLEEN CELL; T LYMPHOCYTE; THYMUS;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIGENS, CD3; APOPTOSIS; AUTISTIC DISORDER; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; FLOW CYTOMETRY; HUMANS; IMMUNITY; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; INTERLEUKIN-2; INTERLEUKIN-4; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; SPLEEN; T-LYMPHOCYTES; THYMOCYTES;

MUS; MUS MUSCULUS;

EID: 84863242859     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-195438     Document Type: Article

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