Tapasin-related protein TAPBPR is an additional component of the MHC class i presentation pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 9, 2013, Pages 3465-3470

  Boyle, Louise H ^a,b   Hermann, Clemens ^a,b   Boname, Jessica M ^a,b   Porter, Keith M ^a,b   Patel, Peysh A ^a,b   Burr, Marian L ^a,b   Duncan, Lidia M ^a,b   Harbour, Michael E ^b   Rhodes, David A ^a,b   Skjødt, Karsten ^c   Lehner, Paul J ^a,b   Trowsdale, John ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; BINDING PROTEIN; CALRETICULIN; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TAP BINDING PROTEIN; TAPASIN; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SECRETORY PATHWAY;

ANTIGEN PRESENTATION; BETA 2-MICROGLOBULIN; CALNEXIN; CALRETICULIN; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; HEK293 CELLS; HELA CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA-A ANTIGENS; HUMANS; IMMUNOGLOBULINS; INTERFERON-GAMMA; KINETICS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; PEPTIDES; PROTEIN BINDING; PROTEIN DISULFIDE-ISOMERASES; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT;

EID: 84874459064     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222342110     Document Type: Article

References (44)

1. Peaper DR, Cresswell P (2008) Regulation of MHC class I assembly and peptide binding. Annu Rev Cell Dev Biol 24: 343-368.
2. Van Hateren A, et al. (2010) The cell biology of major histocompatibility complex class I assembly: Towards a molecular understanding. Tissue Antigens 76(4): 259-275.
3. Sadasivan B, Lehner PJ, Ortmann B, Spies T, Cresswell P (1996) Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP. Immunity 5(2): 103-114.
4. Li S, Sjögren HO, Hellman U, Pettersson RF, Wang P (1997) Cloning and functional characterization of a subunit of the transporter associated with antigen processing. Proc Natl Acad Sci USA 94(16): 8708-8713.
5. Tan P, et al. (2002) Recruitment of MHC class I molecules by tapasin into the transporter associated with antigen processing-associated complex is essential for optimal peptide loading. J Immunol 168(4): 1950-1960.
6. Lehner PJ, Surman MJ, Cresswell P (1998) Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line. 220. Immunity 8(2): 221-231.
7. Bangia N, Lehner PJ, Hughes EA, Surman M, Cresswell P (1999) The N-terminal region of tapasin is required to stabilize the MHC class I loading complex. Eur J Immunol 29(6): 1858-1870.
8. Purcell AW, et al. (2001) Quantitative and qualitative influences of tapasin on the class I peptide repertoire. J Immunol 166(2): 1016-1027.
9. Williams AP, Peh CA, Purcell AW, McCluskey J, Elliott T (2002) Optimization of the MHC class I peptide cargo is dependent on tapasin. Immunity 16(4): 509-520.
10. Wearsch PA, Cresswell P (2007) Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer. Nat Immunol 8(8): 873-881.
11. Chen M, Bouvier M(2007) Analysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection. EMBO J 26(6): 1681-1690.
12. Peh CA, et al. (1998) HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading. Immunity 8(5): 531-542.
13. Park B, Lee S, Kim E, Ahn K (2003) A single polymorphic residue within the peptidebinding cleft of MHC class I molecules determines spectrum of tapasin dependence. J Immunol 170(2): 961-968.
14. Lewis JW, Sewell A, Price D, Elliott T (1998) HLA-A 0201 presents TAP-dependent peptide epitopes to cytotoxic T lymphocytes in the absence of tapasin. Eur J Immunol 28(10): 3214-3220.
15. Ortmann B, et al. (1997) A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes. Science 277(5330): 1306-1309.
16. Garbi N, et al. (2000) Impaired immune responses and altered peptide repertoire in tapasin-deficient mice. Nat Immunol 1(3): 234-238.
17. Grandea AG, 3rd, et al. (2000) Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice. Immunity 13(2): 213-222.
18. Du Pasquier L (2000) The phylogenetic origin of antigen-specific receptors. Curr Top Microbiol Immunol 248: 160-185.
19. Teng MS, et al. (2002) A human TAPBP (TAPASIN)-related gene, TAPBP-R. Eur J Immunol 32(4): 1059-1068.
20. Landis ED, et al. (2006) Identification and regulatory analysis of rainbow trout tapasin and tapasin-related genes. Immunogenetics 58(1): 56-69.
21. Duncan LM, et al. (2012) Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells. PLoS ONE 7(6):e39651.
22. Stam NJ, Spits H, Ploegh HL (1986) Monoclonal antibodies raised against denatured HLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products. J Immunol 137(7): 2299-2306.
23. Perosa F, et al. (2003) Beta 2-microglobulin-free HLA class I heavy chain epitope mimicry by monoclonal antibody HC-10-specific peptide. J Immunol 171(4): 1918-1926.
24. Peaper DR, Wearsch PA, Cresswell P (2005) Tapasin and ERp57 form a stable disulfidelinked dimer within the MHC class I peptide-loading complex. EMBO J 24(20): 3613-3623.
25. Trowsdale J, et al. (1990) Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters. Nature 348(6303): 741-744.
26. Saric T, et al. (2002) An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat Immunol 3(12): 1169-1176.
27. Bangia N, Cresswell P (2005) Stoichiometric tapasin interactions in the catalysis of major histocompatibility complex class I molecule assembly. Immunology 114(3): 346-353.
28. Greenwood R, Shimizu Y, Sekhon GS, DeMars R (1994) Novel allele-specific, posttranslational reduction in HLA class I surface expression in a mutant human B cell line. J Immunol 153(12): 5525-5536.
29. Grandea AG, 3rd, Androlewicz MJ, Athwal RS, Geraghty DE, Spies T (1995) Dependence of peptide binding by MHC class I molecules on their interaction with TAP. Science 270(5233): 105-108.
30. Petersen JL, et al. (2005) A charged amino acid residue in the transmembrane/cytoplasmic region of tapasin influences MHC class I assembly and maturation. J Immunol 174(2): 962-969.
31. Boyle LH, Gillingham AK, Munro S, Trowsdale J (2006) Selective export of HLA-F by its cytoplasmic tail. J Immunol 176(11): 6464-6472.
32. Cho S, Ryoo J, Jun Y, Ahn K (2011) Receptor-mediated ER export of human MHC class I molecules is regulated by the C-terminal single amino acid. Traffic 12(1): 42-55.
33. Abe F, Van Prooyen N, Ladasky JJ, Edidin M (2009) Interaction of Bap31 and MHC class I molecules and their traffic out of the endoplasmic reticulum. J Immunol 182(8): 4776-4783.
34. Ladasky JJ, et al. (2006) Bap31 enhances the endoplasmic reticulum export and quality control of human class I MHC molecules. J Immunol 177(9): 6172-6181.
35. Paquet ME, Cohen-Doyle M, Shore GC, Williams DB (2004) Bap29/31 influences the intracellular traffic of MHC class I molecules. J Immunol 172(12): 7548-7555.
36. Spiliotis ET, Manley H, Osorio M, Zúñiga MC, Edidin M (2000) Selective export of MHC class I molecules from the ER after their dissociation from TAP. Immunity 13(6): 841-851.
37. Garstka M, et al. (2007) Peptide-receptive major histocompatibility complex class I molecules cycle between endoplasmic reticulum and cis-Golgi in wild-type lymphocytes. J Biol Chem 282(42): 30680-30690.
38. Munro S, Pelham HR (1987) A C-terminal signal prevents secretion of luminal ER proteins. Cell 48(5): 899-907.
39. Rajagopalan S, Xu Y, Brenner MB (1994) Retention of unassembled components of integral membrane proteins by calnexin. Science 263(5145): 387-390.
40. Paulsson KM, Jevon M, Wang JW, Li S, Wang P (2006) The double lysine motif of tapasin is a retrieval signal for retention of unstable MHC class I molecules in the endoplasmic reticulum. J Immunol 176(12): 7482-7488.
41. Barnstable CJ, et al. (1978) Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell 14(1): 9-20.
42. Stam NJ, Vroom TM, Peters PJ, Pastoors EB, Ploegh HL (1990) HLA-A- and HLA-Bspecific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy. Int Immunol 2(2): 113-125.
43. Sernee MF, Ploegh HL, Schust DJ (1998) Why certain antibodies cross-react with HLA-A and HLA-G: Epitope mapping of two common MHC class I reagents. Mol Immunol 35(3): 177-188.
44. Skjoedt MO, et al. (2010) Two mannose-binding lectin homologues and an MBLassociated serine protease are expressed in the gut epithelia of the urochordate species Ciona intestinalis. Dev Comp Immunol 34(1): 59-68.