메뉴 건너뛰기




Volumn 33, Issue , 2013, Pages 45-70

Human genetic variation influences vitamin c homeostasis by altering vitamin C transport and antioxidant enzyme function

Author keywords

Ascorbate; GST; Haptoglobin; Polymorphism; SNP; SVCT

Indexed keywords

ASCORBIC ACID; GLUCOSE TRANSPORTER; GLUTATHIONE TRANSFERASE; HAPTOGLOBIN; MANGANESE SUPEROXIDE DISMUTASE;

EID: 84880653572     PISSN: 01999885     EISSN: 15454312     Source Type: Book Series    
DOI: 10.1146/annurev-nutr-071812-161246     Document Type: Article
Times cited : (103)

References (98)
  • 1
    • 0033083920 scopus 로고    scopus 로고
    • Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer
    • Ambrosone CB, Freudenheim JL, Thompson PA, Bowman E, Vena JE, et al. 1999. Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer. Cancer Res. 59:602-6
    • (1999) Cancer Res. , vol.59 , pp. 602-606
    • Ambrosone, C.B.1    Freudenheim, J.L.2    Thompson, P.A.3    Bowman, E.4    Vena, J.E.5
  • 3
    • 77949493346 scopus 로고    scopus 로고
    • Divergent effects of alpha-tocopherol and vitamin C on the generation of dysfunctional HDL associated with diabetes and the Hp 2-2 genotype
    • Asleh R, Levy AP. 2010. Divergent effects of alpha-tocopherol and vitamin C on the generation of dysfunctional HDL associated with diabetes and the Hp 2-2 genotype. Antioxid. Redox Signal. 12:209-17
    • (2010) Antioxid. Redox Signal. , vol.12 , pp. 209-217
    • Asleh, R.1    Levy, A.P.2
  • 4
    • 77951945549 scopus 로고    scopus 로고
    • A diet based on highheat-treated foods promotes risk factors for diabetes mellitus and cardiovascular diseases
    • Birlouez-Aragon I, Saavedra G, Tessier FJ, Galinier A, Ait-Ameur L, et al. 2010. A diet based on highheat-treated foods promotes risk factors for diabetes mellitus and cardiovascular diseases. Am. J. Clin. Nutr. 91:1220-26
    • (2010) Am. J. Clin. Nutr. , vol.91 , pp. 1220-1226
    • Birlouez-Aragon, I.1    Saavedra, G.2    Tessier, F.J.3    Galinier, A.4    Ait-Ameur, L.5
  • 6
    • 80051970943 scopus 로고    scopus 로고
    • Serum vitamin C and other biomarkers differ by genotype of phase 2 enzyme genes GSTM1 and GSTT1
    • Block G, Shaikh N, Jensen CD, Volberg V, Holland N. 2011. Serum vitamin C and other biomarkers differ by genotype of phase 2 enzyme genes GSTM1 and GSTT1. Am. J. Clin. Nutr. 94:929-37
    • (2011) Am. J. Clin. Nutr. , vol.94 , pp. 929-937
    • Block, G.1    Shaikh, N.2    Jensen, C.D.3    Volberg, V.4    Holland, N.5
  • 7
    • 33750143284 scopus 로고    scopus 로고
    • Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: The EPIC-Norfolk prospective population study
    • Boekholdt SM, MeuweseMC, DayNE, Luben R, Welch A, et al. 2006. Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: the EPIC-Norfolk prospective population study. Br. J. Nutr. 96:516-22
    • (2006) Br. J. Nutr. , vol.96 , pp. 516-522
    • Boekholdt, S.M.1    Meuwese, M.C.2    Day, N.E.3    Luben, R.4    Welch, A.5
  • 9
    • 77953931364 scopus 로고    scopus 로고
    • Vitamin C transporter gene polymorphisms, dietary vitamin C and serum ascorbic acid
    • Cahill LE, El-Sohemy A. 2009. Vitamin C transporter gene polymorphisms, dietary vitamin C and serum ascorbic acid. J. Nutrigenet. Nutrigenomics 2:292-301
    • (2009) J. Nutrigenet. Nutrigenomics , vol.2 , pp. 292-301
    • Cahill, L.E.1    El-Sohemy, A.2
  • 10
    • 78651288315 scopus 로고    scopus 로고
    • Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency
    • Cahill LE, El-Sohemy A. 2010. Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency. Am. J. Clin. Nutr. 92:1494-500
    • (2010) Am. J. Clin. Nutr. , vol.92 , pp. 1494-1500
    • Cahill, L.E.1    El-Sohemy, A.2
  • 11
    • 70350633685 scopus 로고    scopus 로고
    • Functional genetic variants of glutathione S-transferase protect against serum ascorbic acid deficiency
    • Cahill LE, Fontaine-BissonB, El-Sohemy A. 2009. Functional genetic variants of glutathione S-transferase protect against serum ascorbic acid deficiency. Am. J. Clin. Nutr. 90:1411-17
    • (2009) Am. J. Clin. Nutr. , vol.90 , pp. 1411-1417
    • Cahill, L.E.1    Fontaine-Bisson, B.2    El-Sohemy, A.3
  • 12
    • 84862140131 scopus 로고    scopus 로고
    • PM10-induced hospital admissions for asthma and chronic obstructive pulmonary disease: The modifying effect of individual characteristics
    • Canova C, Dunster C, Kelly FJ, Minelli C, Shah PL, et al. 2012. PM10-induced hospital admissions for asthma and chronic obstructive pulmonary disease: the modifying effect of individual characteristics. Epidemiology 23:607-15
    • (2012) Epidemiology , vol.23 , pp. 607-615
    • Canova, C.1    Dunster, C.2    Kelly, F.J.3    Minelli, C.4    Shah, P.L.5
  • 13
    • 0032977279 scopus 로고    scopus 로고
    • Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans
    • Carr AC, Frei B. 1999. Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. Am. J. Clin. Nutr. 69:1086-107
    • (1999) Am. J. Clin. Nutr. , vol.69 , pp. 1086-1107
    • Carr, A.C.1    Frei, B.2
  • 14
    • 75149140183 scopus 로고    scopus 로고
    • Site-specific protein adducts of 4-hydroxy-2(E)-nonenal in human THP-1 monocytic cells: Protein carbonylation is diminished by ascorbic acid
    • Chavez J, ChungWG, Miranda CL, SinghalM, Stevens JF, Maier CS. 2010. Site-specific protein adducts of 4-hydroxy-2(E)-nonenal in human THP-1 monocytic cells: Protein carbonylation is diminished by ascorbic acid. Chem. Res. Toxicol. 23:37-47
    • (2010) Chem. Res. Toxicol. , vol.23 , pp. 37-47
    • Chavez, J.1    Chung, W.G.2    Miranda, C.L.3    Singhal, M.4    Stevens, J.F.5    Maier, C.S.6
  • 15
    • 66749121837 scopus 로고    scopus 로고
    • Genetic variation in the vitamin C transporter, SLC23A2, modifies the risk of HPV16-associated head and neck cancer
    • Chen AA, Marsit CJ, Christensen BC, Houseman EA, McClean MD, et al. 2009. Genetic variation in the vitamin C transporter, SLC23A2, modifies the risk of HPV16-associated head and neck cancer. Carcinogenesis 30:977-81
    • (2009) Carcinogenesis , vol.30 , pp. 977-981
    • Chen, A.A.1    Marsit, C.J.2    Christensen, B.C.3    Houseman, E.A.4    McClean, M.D.5
  • 16
    • 0026499456 scopus 로고
    • Sublocalization of the gene encoding manganese superoxide dismutase (MnSOD/SOD2) to 6q25 by fluorescence in situ hybridization and somatic cell hybrid mapping
    • Church SL, Grant JW, Meese EU, Trent JM. 1992. Sublocalization of the gene encoding manganese superoxide dismutase (MnSOD/SOD2) to 6q25 by fluorescence in situ hybridization and somatic cell hybrid mapping. Genomics 14:823-25
    • (1992) Genomics , vol.14 , pp. 823-825
    • Church, S.L.1    Grant, J.W.2    Meese, E.U.3    Trent, J.M.4
  • 17
    • 77951167788 scopus 로고    scopus 로고
    • Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice
    • Corpe CP, Tu H, Eck P, Wang J, Faulhaber-Walter R, et al. 2010. Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice. J. Clin. Investig. 120:1069-83
    • (2010) J. Clin. Investig. , vol.120 , pp. 1069-1083
    • Corpe, C.P.1    Tu, H.2    Eck, P.3    Wang, J.4    Faulhaber-Walter, R.5
  • 18
    • 34548721853 scopus 로고    scopus 로고
    • Haplotype association between haptoglobin (Hp2) and Hp promoter SNP (A-61C) may explain previous controversy of haptoglobin and malaria protection
    • Cox SE, Doherty C, Atkinson SH, Nweneka CV, Fulford AJ, et al. 2007. Haplotype association between haptoglobin (Hp2) and Hp promoter SNP (A-61C) may explain previous controversy of haptoglobin and malaria protection. PLoS ONE 2:e362
    • (2007) PLoS ONE , vol.2
    • Cox, S.E.1    Doherty, C.2    Atkinson, S.H.3    Nweneka, C.V.4    Fulford, A.J.5
  • 19
    • 38349036270 scopus 로고    scopus 로고
    • Is plasma vitamin C an appropriate biomarker of vitamin C intake? A systematic review and meta-analysis
    • Dehghan M, Akhtar-Danesh N, McMillan CR, Thabane L. 2007. Is plasma vitamin C an appropriate biomarker of vitamin C intake? A systematic review and meta-analysis. Nutr. J. 6:41
    • (2007) Nutr. J. , vol.6 , pp. 41
    • Dehghan, M.1    Akhtar-Danesh, N.2    McMillan, C.R.3    Thabane, L.4
  • 22
    • 49049112475 scopus 로고    scopus 로고
    • Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population
    • Dherani M, Murthy GV, Gupta SK, Young IS, Maraini G, et al. 2008. Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population. Investig. Ophthalmol. Vis. Sci. 49:3328-35
    • (2008) Investig. Ophthalmol. Vis. Sci. , vol.49 , pp. 3328-3335
    • Dherani, M.1    Murthy, G.V.2    Gupta, S.K.3    Young, I.S.4    Maraini, G.5
  • 23
    • 77956177703 scopus 로고    scopus 로고
    • Oxidative stress in hypercholesterolemia and its association with Ala16Val superoxide dismutase gene polymorphism
    • Duarte MM, Moresco RN, Duarte T, Santi A, BagatiniMD, et al. 2010. Oxidative stress in hypercholesterolemia and its association with Ala16Val superoxide dismutase gene polymorphism. Clin. Biochem. 43:1118-23
    • (2010) Clin. Biochem. , vol.43 , pp. 1118-1123
    • Duarte, M.M.1    Moresco, R.N.2    Duarte, T.3    Santi, A.4    Bagatini, M.D.5
  • 24
    • 84860532253 scopus 로고    scopus 로고
    • Dietary benzo(a)pyrene and fetal growth: Effect modification by vitamin C intake and glutathione S-transferase P1 polymorphism
    • Duarte-Salles T, Mendez MA, Morales E, Bustamante M, Rodriguez-Vicente A, et al. 2012. Dietary benzo(a)pyrene and fetal growth: effect modification by vitamin C intake and glutathione S-transferase P1 polymorphism. Environ. Int. 45:1-8
    • (2012) Environ. Int. , vol.45 , pp. 1-8
    • Duarte-Salles, T.1    Mendez, M.A.2    Morales, E.3    Bustamante, M.4    Rodriguez-Vicente, A.5
  • 25
    • 0035479750 scopus 로고    scopus 로고
    • Glutathione S-transferase polymorphisms influence the level of oxidative DNA damage and antioxidant protection in humans
    • Dusinska M, Ficek A, Horska A, Raslova K, Petrovska H, et al. 2001. Glutathione S-transferase polymorphisms influence the level of oxidative DNA damage and antioxidant protection in humans. Mutat. Res. 482:47-55
    • (2001) Mutat. Res. , vol.482 , pp. 47-55
    • Dusinska, M.1    Ficek, A.2    Horska, A.3    Raslova, K.4    Petrovska, H.5
  • 26
    • 4544281382 scopus 로고    scopus 로고
    • Comparison of the genomic structure and variation in the two human sodium-dependent vitamin C transporters, SLC23A1 and SLC23A2
    • Eck P, Erichsen HC, Taylor JG, Yeager M, Hughes AL, et al. 2004. Comparison of the genomic structure and variation in the two human sodium-dependent vitamin C transporters, SLC23A1 and SLC23A2. Hum. Genet. 115:285-94
    • (2004) Hum. Genet. , vol.115 , pp. 285-294
    • Eck, P.1    Erichsen, H.C.2    Taylor, J.G.3    Yeager, M.4    Hughes, A.L.5
  • 27
    • 31344462063 scopus 로고    scopus 로고
    • Genetic variation in the sodium-dependent vitamin C transporters, SLC23A1, and SLC23A2 and risk for preterm delivery
    • Erichsen HC, Engel SA, Eck PK, Welch R, Yeager M, et al. 2006. Genetic variation in the sodium-dependent vitamin C transporters, SLC23A1, and SLC23A2 and risk for preterm delivery. Am. J. Epidemiol. 163:245-54
    • (2006) Am. J. Epidemiol. , vol.163 , pp. 245-254
    • Erichsen, H.C.1    Engel, S.A.2    Eck, P.K.3    Welch, R.4    Yeager, M.5
  • 28
    • 51849117309 scopus 로고    scopus 로고
    • Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma
    • Erichsen HC, Peters U, Eck P, Welch R, Schoen RE, et al. 2008. Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma. Nutr. Cancer 60:652-59
    • (2008) Nutr. Cancer , vol.60 , pp. 652-659
    • Erichsen, H.C.1    Peters, U.2    Eck, P.3    Welch, R.4    Schoen, R.E.5
  • 29
    • 1542513683 scopus 로고    scopus 로고
    • Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel
    • FischerH, Schwarzer C, Illek B. 2004. Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel. Proc. Natl. Acad. Sci. USA 101:3691-96
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 3691-3696
    • Fischer, H.1    Schwarzer, C.2    Illek, B.3
  • 30
    • 84865691580 scopus 로고    scopus 로고
    • Authors? perspective: What is the optimum intake of vitamin C in humans?
    • Frei B, Birlouez-Aragon I, Lykkesfeldt J. 2012. Authors' perspective: What is the optimum intake of vitamin C in humans? Crit. Rev. Food Sci. Nutr. 52:815-29
    • (2012) Crit. Rev. Food Sci. Nutr. , vol.52 , pp. 815-829
    • Frei, B.1    Birlouez-Aragon, I.2    Lykkesfeldt, J.3
  • 31
    • 65549098273 scopus 로고    scopus 로고
    • Role of marginal vitamin C deficiency in atherogenesis: In vivo models and clinical studies
    • Frikke-Schmidt H, Lykkesfeldt J. 2009. Role of marginal vitamin C deficiency in atherogenesis: in vivo models and clinical studies. Basic Clin. Pharmacol. Toxicol. 104:419-33
    • (2009) Basic Clin. Pharmacol. Toxicol. , vol.104 , pp. 419-433
    • Frikke-Schmidt, H.1    Lykkesfeldt, J.2
  • 32
    • 0029045975 scopus 로고
    • VitaminCand risk of death from stroke and coronary heart disease in cohort of elderly people
    • Gale CR, Martyn CN, Winter PD, CooperC. 1995. VitaminCand risk of death from stroke and coronary heart disease in cohort of elderly people. BMJ 310:1563-66
    • (1995) BMJ , vol.310 , pp. 1563-1566
    • Gale, C.R.1    Martyn, C.N.2    Winter, P.D.3    Cooper, C.4
  • 33
    • 84862114807 scopus 로고    scopus 로고
    • Genetic architecture of microRNA expression: Implications for the transcriptome and complex traits
    • Gamazon ER, Ziliak D, Im HK, LaCroix B, Park DS, et al. 2012. Genetic architecture of microRNA expression: implications for the transcriptome and complex traits. Am. J. Hum. Genet. 90:1046-63
    • (2012) Am. J. Hum. Genet. , vol.90 , pp. 1046-1063
    • Gamazon, E.R.1    Ziliak, D.2    Im, H.K.3    Lacroix, B.4    Park, D.S.5
  • 34
    • 34548257176 scopus 로고    scopus 로고
    • HIF-dependent antitumorigenic effect of antioxidants in vivo
    • Gao P, Zhang H, Dinavahi R, Li F, Xiang Y, et al. 2007. HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell 12:230-38
    • (2007) Cancer Cell , vol.12 , pp. 230-238
    • Gao, P.1    Zhang, H.2    Dinavahi, R.3    Li, F.4    Xiang, Y.5
  • 35
    • 0028117067 scopus 로고
    • Transport of vitamin C in animal and human cells
    • Goldenberg H, Schweinzer E. 1994. Transport of vitamin C in animal and human cells. J. Bioenerg. Biomembr. 26:359-67
    • (1994) J. Bioenerg. Biomembr. , vol.26 , pp. 359-367
    • Goldenberg, H.1    Schweinzer, E.2
  • 36
    • 84860425021 scopus 로고    scopus 로고
    • Haptoglobin genotype and its role in determining heme-iron mediated vascular disease
    • Goldenstein H, Levy NS, Levy AP. 2012. Haptoglobin genotype and its role in determining heme-iron mediated vascular disease. Pharmacol. Res. 66:1-6
    • (2012) Pharmacol. Res. , vol.66 , pp. 1-6
    • Goldenstein, H.1    Levy, N.S.2    Levy, A.P.3
  • 37
    • 33845892133 scopus 로고    scopus 로고
    • Manganese superoxide dismutase polymorphism and risk of skin cancer (United States
    • Han J, Colditz GA, Hunter DJ. 2007. Manganese superoxide dismutase polymorphism and risk of skin cancer (United States). Cancer Causes Control 18:79-89
    • (2007) Cancer Causes Control , vol.18 , pp. 79-89
    • Han, J.1    Colditz, G.A.2    Hunter, D.J.3
  • 38
    • 84864663987 scopus 로고    scopus 로고
    • MicroRNA-30b-mediated regulation of catalase expression in human ARPE-19 cells
    • 2542
    • Haque R, Chun E, Howell JC, Sengupta T, Chen D, Kim H. 2012. MicroRNA-30b-mediated regulation of catalase expression in human ARPE-19 cells. PLoS ONE 7:e4 2542
    • (2012) PLoS ONE , vol.7
    • Haque, R.1    Chun, E.2    Howell, J.C.3    Sengupta, T.4    Chen, D.5    Kim, H.6
  • 42
  • 43
    • 33750438130 scopus 로고    scopus 로고
    • Plasma and dietary vitamin C levels and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST
    • Jenab M, Riboli E, Ferrari P, Sabate J, Slimani N, et al. 2006. Plasma and dietary vitamin C levels and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Carcinogenesis 27:2250-57
    • (2006) Carcinogenesis , vol.27 , pp. 2250-2257
    • Jenab, M.1    Riboli, E.2    Ferrari, P.3    Sabate, J.4    Slimani, N.5
  • 44
    • 84860278737 scopus 로고    scopus 로고
    • Effects of vitamin C supplementation on blood pressure: A meta-analysis of randomized controlled trials
    • Juraschek SP, Guallar E, Appel LJ, Miller ER 3rd. 2012. Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials. Am. J. Clin. Nutr. 95:1079-88
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 1079-1088
    • Juraschek, S.P.1    Guallar, E.2    Appel, L.J.3    Miller Iii, E.R.4
  • 45
    • 33847066356 scopus 로고    scopus 로고
    • Regulation of UVB-induced IL-8 and MCP-1 production in skin keratinocytes by increasing vitamin C uptake via the redistribution of SVCT-1 from the cytosol to the membrane
    • Kang JS, Kim HN, Jung DJ, Kim JE, Mun GH, et al. 2007. Regulation of UVB-induced IL-8 and MCP-1 production in skin keratinocytes by increasing vitamin C uptake via the redistribution of SVCT-1 from the cytosol to the membrane. J. Investig. Dermatol. 127:698-706
    • (2007) J. Investig. Dermatol. , vol.127 , pp. 698-706
    • Kang, J.S.1    Kim, H.N.2    Jung, D.J.3    Kim, J.E.4    Mun, G.H.5
  • 46
    • 18244383824 scopus 로고    scopus 로고
    • Effect of transferrin polymorphism on the metabolism of vitamin C in Zimbabwean adults
    • Kasvosve I, Delanghe J.R., Gomo ZA, Gangaidzo IT, Khumalo H, et al. 2002. Effect of transferrin polymorphism on the metabolism of vitamin C in Zimbabwean adults. Am. J. Clin. Nutr. 75:321-25
    • (2002) Am. J. Clin. Nutr. , vol.75 , pp. 321-325
    • Kasvosve, I.1    Delanghe, J.R.2    Gomo, Z.A.3    Gangaidzo, I.T.4    Khumalo, H.5
  • 47
    • 0035799105 scopus 로고    scopus 로고
    • Relation between plasma ascorbic acid andmortality inmen and women in EPIC-Norfolk prospective study: A prospective population study. European Prospective Investigation into Cancer and Nutrition
    • Khaw KT, Bingham S, Welch A, Luben R, Wareham N, et al. 2001. Relation between plasma ascorbic acid andmortality inmen and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition. Lancet 357:657-63
    • (2001) Lancet , vol.357 , pp. 657-663
    • Khaw, K.T.1    Bingham, S.2    Welch, A.3    Luben, R.4    Wareham, N.5
  • 48
    • 0031876240 scopus 로고    scopus 로고
    • Deficient transport of dehydroascorbic acid in the glucose transporter protein syndrome
    • Klepper J, Vera JC, De Vivo DC. 1998. Deficient transport of dehydroascorbic acid in the glucose transporter protein syndrome. Ann. Neurol. 44:286-87
    • (1998) Ann. Neurol. , vol.44 , pp. 286-287
    • Klepper, J.1    Vera, J.C.2    De Vivo, D.C.3
  • 49
    • 0032943723 scopus 로고    scopus 로고
    • Defective glucose transport across brain tissue barriers: A newly recognized neurological syndrome
    • Klepper J, Wang D, Fischbarg J, Vera JC, Jarjour IT, et al. 1999. Defective glucose transport across brain tissue barriers: a newly recognized neurological syndrome. Neurochem. Res. 24:587-94
    • (1999) Neurochem. Res. , vol.24 , pp. 587-594
    • Klepper, J.1    Wang, D.2    Fischbarg, J.3    Vera, J.C.4    Jarjour, I.T.5
  • 50
    • 79951812882 scopus 로고    scopus 로고
    • Negative regulation of the tumor suppressor p53 gene by microRNAs
    • Kumar M, Lu Z, Takwi AA, Chen W, Callander NS, et al. 2011. Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene 30:843-53
    • (2011) Oncogene , vol.30 , pp. 843-853
    • Kumar, M.1    Lu, Z.2    Takwi, A.A.3    Chen, W.4    Callander, N.S.5
  • 52
    • 77956512504 scopus 로고    scopus 로고
    • Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: Mechanistic insight into arterial tortuosity syndrome
    • Lee YC, Huang HY, Chang CJ, Cheng CH, Chen YT. 2010. Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome. Hum. Mol. Genet. 19:3721-33
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 3721-3733
    • Lee, Y.C.1    Huang, H.Y.2    Chang, C.J.3    Cheng, C.H.4    Chen, Y.T.5
  • 53
    • 9244219627 scopus 로고    scopus 로고
    • Vitamin C pharmacokinetics in healthy volunteers: Evidence for a recommended dietary allowance
    • Levine M, Conry-Cantilena C, Wang Y, Welch RW, Washko PW, et al. 1996. Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. Proc. Natl. Acad. Sci. USA 93:3704-9
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3704-3709
    • Levine, M.1    Conry-Cantilena, C.2    Wang, Y.3    Welch, R.W.4    Washko, P.W.5
  • 54
    • 0035859936 scopus 로고    scopus 로고
    • A new recommended dietary allowance of vitamin C for healthy young women
    • Levine M, Wang Y, Padayatty SJ, Morrow J. 2001. A new recommended dietary allowance of vitamin C for healthy young women. Proc. Natl. Acad. Sci. USA 98:9842-46
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9842-9846
    • Levine, M.1    Wang, Y.2    Padayatty, S.J.3    Morrow, J.4
  • 56
    • 77952575259 scopus 로고    scopus 로고
    • Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials
    • Lykkesfeldt J, Poulsen HE. 2010. Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials. Br. J. Nutr. 103:1251-59
    • (2010) Br. J. Nutr. , vol.103 , pp. 1251-1259
    • Lykkesfeldt, J.1    Poulsen, H.E.2
  • 57
    • 82555204538 scopus 로고    scopus 로고
    • Hepatic expression of sodium-dependent vitamin C transporters: Ontogeny, subtissular distribution and effect of chronic liver diseases
    • Macias RI, Hierro C, de Juan SC, Jimenez F, Gonzalez-SanMartin F, Marin JJ. 2011. Hepatic expression of sodium-dependent vitamin C transporters: ontogeny, subtissular distribution and effect of chronic liver diseases. Br. J. Nutr. 106:1814-25
    • (2011) Br. J. Nutr. , vol.106 , pp. 1814-1825
    • Macias, R.I.1    Hierro, C.2    De Juan, S.C.3    Jimenez, F.4    Gonzalez-San Martin, F.5    Marin, J.J.6
  • 58
    • 0038660743 scopus 로고    scopus 로고
    • Up-regulation and polarized expression of the sodium-ascorbic acid transporter SVCT1 in post-confluent differentiated CaCo-2 cells
    • Maulen NP, Henriquez EA, Kempe S, Carcamo JG, Schmid-Kotsas A, et al. 2003. Up-regulation and polarized expression of the sodium-ascorbic acid transporter SVCT1 in post-confluent differentiated CaCo-2 cells. J. Biol. Chem. 278:9035-41
    • (2003) J. Biol. Chem. , vol.278 , pp. 9035-9041
    • Maulen, N.P.1    Henriquez, E.A.2    Kempe, S.3    Carcamo, J.G.4    Schmid-Kotsas, A.5
  • 60
    • 33645111448 scopus 로고    scopus 로고
    • Glutathione S-transferase polymorphisms: Cancer incidence and therapy
    • McIlwain CC, Townsend DM, Tew KD. 2006. Glutathione S-transferase polymorphisms: cancer incidence and therapy. Oncogene 25:1639-48
    • (2006) Oncogene , vol.25 , pp. 1639-1648
    • McIlwain, C.C.1    Townsend, D.M.2    Tew, K.D.3
  • 61
    • 80555148143 scopus 로고    scopus 로고
    • Differential regulation of the ascorbic acid transporter SVCT2 during development and in response to ascorbic acid depletion
    • MeredithME, Harrison FE, MayJM. 2011. Differential regulation of the ascorbic acid transporter SVCT2 during development and in response to ascorbic acid depletion. Biochem. Biophys. Res. Commun. 414:737-42
    • (2011) Biochem. Biophys. Res. Commun. , vol.414 , pp. 737-742
    • Meredith, M.E.1    Harrison, F.E.2    May, J.M.3
  • 63
    • 70449652284 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 1 is essential for transcription of sodiumdependent vitamin C transporter protein 1
    • Michels AJ, Hagen TM. 2009. Hepatocyte nuclear factor 1 is essential for transcription of sodiumdependent vitamin C transporter protein 1. Am. J. Physiol. Cell Physiol. 297:C1220-27
    • (2009) Am. J. Physiol. Cell Physiol. , vol.297
    • Michels, A.J.1    Hagen, T.M.2
  • 64
    • 67649908957 scopus 로고    scopus 로고
    • Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells
    • Miranda CL, Reed RL, Kuiper HC, Alber S, Stevens JF. 2009. Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells. Chem. Res. Toxicol. 22:863-74
    • (2009) Chem. Res. Toxicol. , vol.22 , pp. 863-874
    • Miranda, C.L.1    Reed, R.L.2    Kuiper, H.C.3    Alber, S.4    Stevens, J.F.5
  • 65
    • 38149104641 scopus 로고    scopus 로고
    • Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer Norfolk prospective population study
    • Myint PK, Luben RN, Welch AA, Bingham SA, Wareham NJ, Khaw KT. 2008. Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer Norfolk prospective population study. Am. J. Clin. Nutr. 87:64-69
    • (2008) Am. J. Clin. Nutr. , vol.87 , pp. 64-69
    • Myint, P.K.1    Luben, R.N.2    Welch, A.A.3    Bingham, S.A.4    Wareham, N.J.5    Khaw, K.T.6
  • 66
    • 32044432346 scopus 로고    scopus 로고
    • Serum vitamin C concentration is influenced by haptoglobin polymorphism and iron status in Chinese
    • Na N, Delanghe J.R., Taes YE, Torck M, BaeyensWR, Ouyang J. 2006. Serum vitamin C concentration is influenced by haptoglobin polymorphism and iron status in Chinese. Clin. Chim. Acta 365:319-24
    • (2006) Clin. Chim. Acta , vol.365 , pp. 319-324
    • Na, N.1    Delanghe, J.R.2    Taes, Y.E.3    Torck, M.4    Baeyens, W.R.5    Ouyang, J.6
  • 67
    • 4844231979 scopus 로고    scopus 로고
    • Haptoglobin genotypic distribution (including Hp0 allele) and associated serum haptoglobin concentrations in Koreans
    • Park KU, Song J, Kim JQ. 2004. Haptoglobin genotypic distribution (including Hp0 allele) and associated serum haptoglobin concentrations in Koreans. J. Clin. Pathol. 57:1094-95
    • (2004) J. Clin. Pathol. , vol.57 , pp. 1094-1095
    • Park, K.U.1    Song, J.2    Kim, J.Q.3
  • 68
    • 80051671262 scopus 로고    scopus 로고
    • Plasma vitamin C predicts incident heart failure in men and women in European Prospective Investigation into Cancer and Nutrition-Norfolk prospective study
    • Pfister R, Sharp SJ, Luben R, Wareham NJ, Khaw KT. 2011. Plasma vitamin C predicts incident heart failure in men and women in European Prospective Investigation into Cancer and Nutrition-Norfolk prospective study. Am. Heart. J. 162:246-53
    • (2011) Am. Heart. J. , vol.162 , pp. 246-253
    • Pfister, R.1    Sharp, S.J.2    Luben, R.3    Wareham, N.J.4    Khaw, K.T.5
  • 69
    • 84856692905 scopus 로고    scopus 로고
    • Nitric oxide modulates sodium vitamin C transporter 2 (SVCT-2) protein expression via protein kinase G (PKG) and nuclear factor-κB (NF-κB
    • Portugal CC, da Encarnacao TG, Socodato R, Moreira SR, Brudzewsky D, et al. 2012. Nitric oxide modulates sodium vitamin C transporter 2 (SVCT-2) protein expression via protein kinase G (PKG) and nuclear factor-κB (NF-κB). J. Biol. Chem. 287:3860-72
    • (2012) J. Biol. Chem. , vol.287 , pp. 3860-3872
    • Portugal, C.C.1    Da Encarnacao, T.G.2    Socodato, R.3    Moreira, S.R.4    Brudzewsky, D.5
  • 70
    • 63049084833 scopus 로고    scopus 로고
    • Macrophage differentiation increases expression of the ascorbate transporter (SVCT2
    • Qiao H, May JM. 2009. Macrophage differentiation increases expression of the ascorbate transporter (SVCT2). Free Radic. Biol. Med. 46:1221-32
    • (2009) Free Radic. Biol. Med. , vol.46 , pp. 1221-1232
    • Qiao, H.1    May, J.M.2
  • 71
    • 80054918413 scopus 로고    scopus 로고
    • CpG methylation at the USF-binding site mediates cell-specific transcription of human ascorbate transporter SVCT2 exon 1a
    • Qiao H, May JM. 2011. CpG methylation at the USF-binding site mediates cell-specific transcription of human ascorbate transporter SVCT2 exon 1a. Biochem. J. 440:73-84
    • (2011) Biochem. J. , vol.440 , pp. 73-84
    • Qiao, H.1    May, J.M.2
  • 72
    • 79953241506 scopus 로고    scopus 로고
    • Regulation of the human ascorbate transporter SVCT2 exon 1b gene by zincfinger transcription factors
    • Qiao H, May JM. 2011. Regulation of the human ascorbate transporter SVCT2 exon 1b gene by zincfinger transcription factors. Free Radic. Biol. Med. 50:1196-209
    • (2011) Free Radic. Biol. Med. , vol.50 , pp. 1196-1209
    • Qiao, H.1    May, J.M.2
  • 73
    • 0033533578 scopus 로고    scopus 로고
    • Human placental sodium-dependent vitamin C transporter (SVCT2): Molecular cloning and transport function
    • Rajan DP, Huang W, Dutta B, Devoe LD, Leibach FH, et al. 1999. Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function. Biochem. Biophys. Res. Commun. 262:762-68
    • (1999) Biochem. Biophys. Res. Commun. , vol.262 , pp. 762-768
    • Rajan, D.P.1    Huang, W.2    Dutta, B.3    Devoe, L.D.4    Leibach, F.H.5
  • 74
    • 80053584650 scopus 로고    scopus 로고
    • Inverse association of vitamin C with cataract in older people in India
    • e2
    • Ravindran RD, Vashist P, Gupta SK, Young IS, Maraini G, et al. 2011. Inverse association of vitamin C with cataract in older people in India. Ophthalmology 118:1958-65.e2
    • (2011) Ophthalmology , vol.118 , pp. 1958-1965
    • Ravindran, R.D.1    Vashist, P.2    Gupta, S.K.3    Young, I.S.4    Maraini, G.5
  • 75
    • 79952538105 scopus 로고    scopus 로고
    • Promoter analysis of the human ascorbic acid transporters SVCT1 and 2: Mechanisms of adaptive regulation in liver epithelial cells
    • Reidling JC, Rubin SA. 2011. Promoter analysis of the human ascorbic acid transporters SVCT1 and 2: mechanisms of adaptive regulation in liver epithelial cells. J. Nutr. Biochem. 22:344-50
    • (2011) J. Nutr. Biochem. , vol.22 , pp. 344-350
    • Reidling, J.C.1    Rubin, S.A.2
  • 76
    • 33144455402 scopus 로고    scopus 로고
    • Functional analysis of two regulatory regions of the human Na+-dependent vitamin C transporter 2, SLC23A2, in human vascular smooth muscle cells
    • Rubin SA, Dey S, Reidling JC. 2005. Functional analysis of two regulatory regions of the human Na+-dependent vitamin C transporter 2, SLC23A2, in human vascular smooth muscle cells. Biochim. Biophys. Acta 1732:76-81
    • (2005) Biochim. Biophys. Acta , vol.1732 , pp. 76-81
    • Rubin, S.A.1    Dey, S.2    Reidling, J.C.3
  • 79
    • 33846847628 scopus 로고    scopus 로고
    • Translational control of the ascorbic acid transporter SVCT2 in human platelets
    • Savini I, Catani MV, Arnone R, Rossi A, Frega G, et al. 2007. Translational control of the ascorbic acid transporter SVCT2 in human platelets. Free Radic. Biol. Med. 42:608-16
    • (2007) Free Radic. Biol. Med. , vol.42 , pp. 608-616
    • Savini, I.1    Catani, M.V.2    Arnone, R.3    Rossi, A.4    Frega, G.5
  • 82
    • 50949118324 scopus 로고    scopus 로고
    • Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma
    • Skibola CF, Bracci PM, Halperin E, Nieters A, Hubbard A, et al. 2008. Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma. PLoS ONE 3:e2816
    • (2008) PLoS ONE , vol.3
    • Skibola, C.F.1    Bracci, P.M.2    Halperin, E.3    Nieters, A.4    Hubbard, A.5
  • 83
    • 85047699109 scopus 로고    scopus 로고
    • Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival
    • Sotiriou S, Gispert S, Cheng J, Wang Y, Chen A, et al. 2002. Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival. Nat. Med. 8:514-17
    • (2002) Nat. Med. , vol.8 , pp. 514-517
    • Sotiriou, S.1    Gispert, S.2    Cheng, J.3    Wang, Y.4    Chen, A.5
  • 84
    • 18744396930 scopus 로고    scopus 로고
    • Themanganese superoxide dismutase Ala16Val dimorphism modulates bothmitochondrial import andmRNAstability
    • SuttonA, ImbertA, Igoudjil A, Descatoire V, Cazanave S, et al. 2005. Themanganese superoxide dismutase Ala16Val dimorphism modulates bothmitochondrial import andmRNAstability. Pharmacogenet. Genomics 15:311-19
    • (2005) Pharmacogenet. Genomics , vol.15 , pp. 311-319
    • Sutton, A.1    Imbert, A.2    Igoudjil, A.3    Descatoire, V.4    Cazanave, S.5
  • 85
    • 77955500681 scopus 로고    scopus 로고
    • Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): Evidence from 5 independent studies with >15,000 participants
    • Timpson NJ, Forouhi NG, Brion MJ, Harbord RM, Cook DG, et al. 2010. Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants. Am. J. Clin. Nutr. 92:375-82
    • (2010) Am. J. Clin. Nutr. , vol.92 , pp. 375-382
    • Timpson, N.J.1    Forouhi, N.G.2    Brion, M.J.3    Harbord, R.M.4    Cook, D.G.5
  • 86
    • 0033529002 scopus 로고    scopus 로고
    • A family of mammalian Na+-dependent L-ascorbic acid transporters
    • Tsukaguchi H, Tokui T, Mackenzie B, Berger UV, Chen XZ, et al. 1999. A family of mammalian Na+-dependent L-ascorbic acid transporters. Nature 399:70-75
    • (1999) Nature , vol.399 , pp. 70-75
    • Tsukaguchi, H.1    Tokui, T.2    Mackenzie, B.3    Berger, U.V.4    Chen, X.Z.5
  • 87
    • 0036276516 scopus 로고    scopus 로고
    • VitaminCis associated with reduced risk of cataract in a Mediterranean population
    • Valero MP, Fletcher AE, De Stavola BL, Vioque J, Alepuz VC. 2002. VitaminCis associated with reduced risk of cataract in a Mediterranean population. J. Nutr. 132:1299-306
    • (2002) J. Nutr. , vol.132 , pp. 1299-1306
    • Valero, M.P.1    Fletcher, A.E.2    De Stavola, B.L.3    Vioque, J.4    Alepuz, V.C.5
  • 88
    • 84861037678 scopus 로고    scopus 로고
    • Is it time to screen for the haptoglobin genotype to assess the cardiovascular risk profile and vitamin e therapy responsiveness in patients with diabetes?
    • Vardi M, Levy AP. 2012. Is it time to screen for the haptoglobin genotype to assess the cardiovascular risk profile and vitamin E therapy responsiveness in patients with diabetes? Curr. Diab. Rep. 12:274-79
    • (2012) Curr. Diab. Rep. , vol.12 , pp. 274-279
    • Vardi, M.1    Levy, A.P.2
  • 89
    • 0027302594 scopus 로고
    • Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid
    • Vera JC, Rivas CI, Fischbarg J, Golde DW. 1993. Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid. Nature 364:79-82
    • (1993) Nature , vol.364 , pp. 79-82
    • Vera, J.C.1    Rivas, C.I.2    Fischbarg, J.3    Golde, D.W.4
  • 90
    • 0242662830 scopus 로고    scopus 로고
    • Dietary antioxidants and the risk of ischemic stroke: The Rotterdam Study
    • Voko Z, Hollander M, Hofman A, Koudstaal PJ, Breteler MM. 2003. Dietary antioxidants and the risk of ischemic stroke: the Rotterdam Study. Neurology 61:1273-75
    • (2003) Neurology , vol.61 , pp. 1273-1275
    • Voko, Z.1    Hollander, M.2    Hofman, A.3    Koudstaal, P.J.4    Breteler, M.M.5
  • 91
    • 0033375028 scopus 로고    scopus 로고
    • Human Na(+)-dependent vitamin C transporter 1 (hSVCT1): Primary structure, functional characteristics and evidence for a non-functional splice variant
    • Wang H, Dutta B, Huang W, Devoe LD, Leibach FH, et al. 1999. Human Na(+)-dependent vitamin C transporter 1 (hSVCT1): primary structure, functional characteristics and evidence for a non-functional splice variant. Biochim. Biophys. Acta 1461:1-9
    • (1999) Biochim. Biophys. Acta , vol.1461 , pp. 1-9
    • Wang, H.1    Dutta, B.2    Huang, W.3    Devoe, L.D.4    Leibach, F.H.5
  • 92
    • 35348993660 scopus 로고    scopus 로고
    • GSTM1 and GSTT1 polymorphism influences protection against induced oxidative DNA damage by quercetin and ascorbic acid in human lymphocytes in vitro
    • Wilms LC, Claughton TA, de Kok TM, Kleinjans JC. 2007. GSTM1 and GSTT1 polymorphism influences protection against induced oxidative DNA damage by quercetin and ascorbic acid in human lymphocytes in vitro. Food Chem. Toxicol. 45:2592-96
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 2592-2596
    • Wilms, L.C.1    Claughton, T.A.2    De Kok, T.M.3    Kleinjans, J.C.4
  • 93
    • 23944482400 scopus 로고    scopus 로고
    • Regulation of vitamin C transport
    • Wilson JX. 2005. Regulation of vitamin C transport. Annu. Rev. Nutr. 25:105-25
    • (2005) Annu. Rev. Nutr. , vol.25 , pp. 105-125
    • Wilson, J.X.1
  • 94
    • 66749118481 scopus 로고    scopus 로고
    • Genetic variation in sodiumdependent ascorbic acid transporters and risk of gastric cancer in Poland
    • Wright ME, Andreotti G, Lissowska J, Yeager M, Zatonski W, et al. 2009. Genetic variation in sodiumdependent ascorbic acid transporters and risk of gastric cancer in Poland. Eur. J. Cancer 45:1824-30
    • (2009) Eur. J. Cancer , vol.45 , pp. 1824-1830
    • Wright, M.E.1    Andreotti, G.2    Lissowska, J.3    Yeager, M.4    Zatonski, W.5
  • 95
    • 39349104016 scopus 로고    scopus 로고
    • Antioxidant vitamins intake and the risk of coronary heart disease: Meta-analysis of cohort studies
    • Ye Z, Song H. 2008. Antioxidant vitamins intake and the risk of coronary heart disease: meta-analysis of cohort studies. Eur. J. Cardiovasc. Prev. Rehabil. 15:26-34
    • (2008) Eur. J. Cardiovasc. Prev. Rehabil. , vol.15 , pp. 26-34
    • Ye, Z.1    Song, H.2
  • 96
    • 84858797896 scopus 로고    scopus 로고
    • The role of glutathione S-transferaseM1 and T1 gene polymorphisms and fruit and vegetable consumption in antioxidant parameters in healthy subjects
    • Yuan LH, Meng LP, MaWW, Li S, Feng JF, et al. 2012. The role of glutathione S-transferaseM1 and T1 gene polymorphisms and fruit and vegetable consumption in antioxidant parameters in healthy subjects. Br. J. Nutr. 107:928-33
    • (2012) Br. J. Nutr. , vol.107 , pp. 928-933
    • Yuan, L.H.1    Meng, L.P.2    Ma, W.W.3    Li, S.4    Feng, J.F.5
  • 97
    • 83055178297 scopus 로고    scopus 로고
    • Association between a SLC23A2 gene variation, plasma vitamin C levels, and risk of glaucoma in a Mediterranean population
    • Zanon-Moreno V, Ciancotti-Olivares L, Asencio J, Sanz P, Ortega-Azorin C, et al. 2011. Association between a SLC23A2 gene variation, plasma vitamin C levels, and risk of glaucoma in a Mediterranean population. Mol. Vis. 17:2997-3004
    • (2011) Mol. Vis. , vol.17 , pp. 2997-3004
    • Zanon-Moreno, V.1    Ciancotti-Olivares, L.2    Asencio, J.3    Sanz, P.4    Ortega-Azorin, C.5
  • 98
    • 84862022469 scopus 로고    scopus 로고
    • Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases
    • Zhou H, Brock J, Liu D, Board PG, Oakley AJ. 2012. Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases. J. Mol. Biol. 420:190-203
    • (2012) J. Mol. Biol. , vol.420 , pp. 190-203
    • Zhou, H.1    Brock, J.2    Liu, D.3    Board, P.G.4    Oakley, A.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.