Regulation of UVB-induced IL-8 and MCP-1 production in skin keratinocytes by increasing vitamin C uptake via the redistribution of SVCT-1 from the cytosol to the membrane

Journal of Investigative Dermatology

Volumn 127, Issue 3, 2007, Pages 698-706

  Kang, Jae Seung ^a   Kim, Ha Na ^a   Jung, Da Jung ^a   Kim, Jee Eun ^a   Mun, Ga Hee ^a   Kim, Yeong Seok ^b   Cho, Daeho ^c   Shin, Dong Hoon ^a   Hwang, Young Il ^a   Lee, Wang Jae ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Inje University College of Medicine   (South Korea)

^c Sookmyung Women's University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; CHEMOKINE; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN; SODIUM DEPENDENT VITAMIN C TRANSPORTER 1; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSOL; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INFLAMMATION; KERATINOCYTE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIBONUCLEASE PROTECTION ASSAY; SKIN; SKIN INFLAMMATION; ULTRAVIOLET B RADIATION;

EID: 33847066356     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700572     Document Type: Article

References (48)

1. Aragane Y, Yamada H, Schwarz A, Poppelmann B, Luger TA, Tezuka T et al. (1996) Transforming growth factor-alpha induces interleukin-6 in the human keratinocyte cell line HaCaT mainly by transcriptional activation. J Invest Dermatol 106:1192-7
2. Ariizumi K, Meng Y, Bergstresser PR, Takashima A (1995) Interferon-gammadependent IL-7 gene regulation in keratinocytes. J Immunol 154:6031-9
3. Baggiolini M, Dewald B, Moser B (1997) Human chemokines: an update. Annu Rev Immunol 15:675-705
4. Beak SM, Lee YS, Kim JA (2004) NADPH oxidase and cyclooxygenase mediate the ultraviolet B-induced generation of reactive oxygen species and activation of nuclear factor-kappaB in HaCaT human keratinocytes. Biochimie 86:425-9
5. Blauvelt A, Asada H, Klaus-Kovtun V, Altman DJ, Lucey DR, Katz SI (1996) Interleukin-15 mRNA is expressed by human keratinocytes, Langerhans cells, and blood-derived dendritic cells and is downregulated by ultraviolet B radiation. J Invest Dermatol 106:1047-52
6. Bogdan C, Rollinghoff M, Diefenbach A (2000) Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity. Curr Opin Immunol 12:64-76
7. Bowie AG, O'Neill LA (2000) Vitamin C inhibits NF-kappa B activation by TNF via the activation of p38 mitogen-activated protein kinase. J Immunol 165:7180-8
8. Chiu C, Maddock DA, Zhang Q, Souza KP, Townsend AR, Wan Y (2001) TGF-beta-induced p38 activation is mediated by Rac1-regulated generation of reactive oxygen species in cultured human keratinocytes. Int J Mol Med 8:251-5
9. Cho D, Hahm E, Kang JS, Kim YI, Yang Y, Park JH et al. (2003) Vitamin C downregulates interleukin-18 production by increasing reactive oxygen intermediate and mitogen-activated protein kinase signalling in B16F10 murine melanoma cells. Melanoma Res 13:549-54
10. Cho JW, Park K, Kweon GR, Jang BC, Baek WK, Suh MH et al. (2005) Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets. Exp Mol Med 30:186-92
11. Daruwala R, Song J, Koh WS, Rumsey SC, Levine M (1999) Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2. FEBS Lett 460:480-4
12. de Vos S, Brach M, Budnik A, Grewe M, Herrmann F, Krutmann J (1993) Posttranscriptional regulation of interleukin-6 gene expression in human keratinocytes by ultraviolet B radiation. J Invest Dermatol 103:92-6
13. Eton O, Kharkevitch DD, Gianan MA, Ross MI, Itoh K, Pride MW et al. (1998) Active immunotherapy with ultraviolet B-irradiated autologous whole melanoma cells plus DETOX in patients with metastatic melanoma. Clin Cancer Res 4:619-27
14. Gossart S, Cambon C, Orfila C, Sequelas MH, Lepert JC, Rami J et al. (1996) Reactive oxygen intermediates as regulators of TNF-alpha production in rat lung inflammation induced by silica. J Immunol 156:1540-8
15. Hall DJ, Bates ME, Guar L, Cronan M, Korpi N, Bertics PJ (2005) The role of p38 MAPK in rhinovirus-induced monocyte chemoattractant protein-1 production by monocytic-lineage cells. J Immunol 174:8056-63
16. Huang S, Mills L, Mian B, Tellez C, McCarty M, Yang XD et al. (2002) Fully humanised neutralising antibodies to interleukin-8 inhibit angiogenesis, tumour growth, and metastasis of human melanoma. Am J Pathol 161:125-34
17. Kim AL, Labasi JM, Zhu Y, Tang X, McClure K, Gabel CA et al. (2005) Role of p38 MAPK in UVB-induced inflammatory responses in the skin of SKH-1 hairless mice. J Invest Dermatol 124:1318-25
18. Kondo S, Kono T, Sauder DN, McKenzie RC (1993) IL-8 gene expression and production in human keratinocytes and their modulation by UVB. J Invest Dermatol 101:690-4
19. Masamitsu I, Nazim UA, Arief B, An W, Toshinori B, Masato U et al. (2000) Preventive effect of antioxidant on ultraviolet-induced skin cancer in mice. J Dermatol Sci 23(Suppl 1):S45-50
20. Matthias AH (2002) New view at C. Nat Med 8:445-6
21. McGowan K, DeVente J, Carey JO,Ways DK, Pekala PH (1996) Protein kinase C isoform expression during the differentiation of 3T3-L1 preadipocytes: loss of protein kinase C-alpha isoform correlates with loss of phorbol 12- myristate 13-acetate activation of nuclear factor kappaB and acquisition of the adipocyte phenotype. J Cell Physiol 16:113-20
22. Nakamura T, Pinnell SR, Darr D, Kurimoto I, Itami S, Yoshikawa K et al. (1997) Vitamin C abrogates the deleterious effects of UVB radiation on cutaneous immunity by a mechanism that does not depend on TNF-alpha. J Invest Dermatol 109:20-4
23. Niederkorn JY, Callanan D, Ross JR (1990) Prevention of the induction of allospecific cytotoxic T lymphocyte and delayed-type hypersensitivity responses by ultraviolet irradiation of corneal allografts. Transplantation 50:281-6
24. Pernet I, Sagot V, Schmitt D, Viac J (1999) UVA1 and UVB radiation but not PGE2 stimulate IL-8 release in normal human keratinocytes. Arch Dermatol Res 291:527-9
25. Rajan DP, Huang W, Dutta B, Devoe LD, Leibach FH, Ganapathy V et al. (1999) Human placental sodium-dependent vitamin C Transporter (SVCT2): molecular cloning and transport function. Biochem Biophys Res Commun 262:762-8
26. Reddy GB, Bhat KS (1999) Protection against UVB inactivation (in vitro) of rat lens enzymes by natural antioxidants. Mol Cell Biochem 194:41-5
27. Sabry JH, Fisher KH, Dodds ML (1958) Human utilization of dehydroascorbic acid. J Nutr 64:457-64
28. Sander CS, Chang H, Hamm F, Elsner P, Thiele JJ (2004) Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis. Int J Dermatol 43:326-35
29. Sasaki H, Akamatsu H, Horio T (2000) Protective role of copper, zinc superoxide dismutase against UVB-induced injury of the human keratinocyte cell line HaCaT. J Invest Dermatol 114:502-7
30. Schreck R, Rieber P, Baeuerle PA (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J 10:2247-58
31. Sen CK, Packer L (1996) Antioxidant and redox regulation of gene transcription. FASEB J 10:709-20
32. Simon MM, Aragane Y, Schwarz A, Luger TA, Schwarz T (1994) UVB light induces nuclear factor-κB (NF-κB) activity independently from chromosomal DNA damage in cell-free cytosolic extracts. J Invest Dermatol 102:422-7
33. Stein M, Bernd A, Ramirez-Bosca A, Kippenberger S, Holzmann H (1997) Measurement of anti-inflammatory effects of glucocorticoids on human keratinocytes in vitro. Arzneim-Forsch/Drug Res 47:1266-70
34. Steude J, Kulke R, Christophers E (2002) Interleukin-1-stimulated secretion of interleukin-8 and growth-related oncogene-alpha demonstrates greatly enhanced keratinocyte growth in human raft cultured epidermis. J Invest Dermatol 119:1254-60
35. Stewart MS, Cameron GS, Pence BC (1996) Antioxidant nutrients protect against UVB-induced oxidative damage to DNA of mouse keratinocytes in culture. J Invest Dermatol 106:1086-9
36. Strickland I, Rhodes LE, Flanagan BF, Friedmann PS (1997) TNF-[alpha] and IL-8 are upregulated in the epidermis of normal human skin after UVB exposure: correlation with neutrophil accumulation and E-Selectin expression. J Invest Dermatol 108:763-8
37. Suh DH, Kwon TE, Youn JI (2002) Changes of comedonal cytokines and sebum secretion after UV irradiation in acne patients. Eur J Dermatol 12:139-44
38. Tanabe S, Taura Y, Tanaka M, Nakaichi M, Nakama S (1993) Suppression of delayed-type hypersensitivity (DTH) responses in xenografts by pretreatment with ultraviolet (UV)-irradiated hepatocytes. J Vet Med Sci 55:853-4
39. Tebbe B, Wu S, Geilen CC, Eberle J, Kodelja V, Orfanos CE (1997) -Ascorbic acid inhibits UVA-induced lipid peroxidation and secretion of IL-1 alpha and IL-6 in cultured human keratinocytes in vitro. J Invest Dermatol 108:302-6
40. Veedamali SS, Jonathan SM, Michael JB, Hamid MS (2004) A C-terminal region dictates the apical plasma membrane targeting of the human sodium-dependent vitamin C transporter-1 in polarized epithelia. J Biol Chem 279:27719-28
41. Wang Y, Mackenzie B, Tsukaguchi H, Weremowicz S, Morton CC, Hediger MA (2000) Human vitamin C (L-ascorbic acid) transporter SVCT1. Biochem Biophys Res Commun 267:488-94
42. Wang ZY, Huang MT, Low YR, Xie JG, Reuhl KR, Newmark HL et al. (1994) Inhibitory effects of black tea, green tea, decaffeinated black tea, and decaffeinated green tea on ultraviolet B light-induced. Cancer Res 54:3428-35
43. Watanabe H, Iwase M, Ohashi M, Nagumo M (2002) Interleukin-8 is an important cytokine involved in tumour growth and angiogenesis in a variety of malignancies. Oral Oncol 38:670-9
44. Weichenthal M, Godorr M, Altenhoff J, Neuber K, Breitbart EW (2000) Effects of whole-body UVB irradiation on cytokine production by peripheral blood mononuclear cells from stage I melanoma patients. Arch Dermatol Res 292:348-53
45. Wilson JX, Dixon SJ (1989) High-affinity sodium-dependent uptake of ascorbic acid by rat osteoblasts. J Membr Bio 111:83-91
46. Wong CK, Wang CB, Ip WK, Tian YP, Lam CW (2005) Role of p38 MAPK and NF-kB for chemokine release in coculture of human eosinophils and bronchial epithelial cells. Clin Exp Immunol 139:90-100
47. Zeng XK, Guan YF, Remick DG, Wang X (2005) Signal pathways underlying homocysteine-induced production of MCP-1 and IL-8 in cultured human whole blood. Acta Pharmacol Sin 26:85-91
48. Zhang QS, Maddock DA, Chen JP, Heo S, Chiu C, Lai D et al. (2001) Cytokine-induced p38 activation feedback regulates the prolonged activation of AKT cell survival pathway initiated by reactive oxygen species in response to UV irradiation in human keratinocytes. Int J Oncol 19:1057-61