Haplotype association between haptoglobin (Hp2) and Hp promoter SNP (A-61C) may explain previous controversy of haptoglobin and malaria protection

PLoS ONE

Volumn 2, Issue 4, 2007, Pages

  Cox, Sharon E ^a   Doherty, Conor ^b   Atkinson, Sarah H ^a,b   Nweneka, Chidi V ^b   Fulford, Anthony J C ^a   Ghattas, Hala ^a   Rockett, Kirk A ^c   Kwiatkowski, Dominic P ^c   Prentice, Andrew M ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; CHLOROQUINE; FANSIDAR; FERROUS SULFATE; HAPTOGLOBIN; HEMOGLOBIN;

AGE DISTRIBUTION; ANEMIA; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE SURVEILLANCE; DISEASE TRANSMISSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; HAPLOTYPE; HEMOGLOBIN SYNTHESIS; HEMOLYSIS; HUMAN; IN VITRO STUDY; INFANT; INFECTION RISK; INFECTION SENSITIVITY; INNATE IMMUNITY; MALARIA; MALARIA CONTROL; OXIDATIVE STRESS; PRESCHOOL CHILD; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RISK ASSESSMENT; SEASONAL VARIATION; SICKLE CELL TRAIT; SINGLE NUCLEOTIDE POLYMORPHISM; TEMPERATURE SENSITIVITY; GENETIC PREDISPOSITION; GENETICS; LONGITUDINAL STUDY; PHYSIOLOGY; STATISTICAL MODEL;

CHILD, PRESCHOOL; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HAPTOGLOBINS; HUMANS; LIKELIHOOD FUNCTIONS; LONGITUDINAL STUDIES; MALARIA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC;

EID: 34548721853     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000362     Document Type: Article

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