Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins

Journal of Experimental Medicine

Volumn 210, Issue 6, 2013, Pages 1201-1216

  Das, Indrajit ^a,b   Png, Chin Wen ^a   Oancea, Iulia ^a,c   Hasnain, Sumaira Z ^a   Lourie, Rohan ^a,c   Proctor, Martina ^a   Eri, Rajaraman D ^a,d   Sheng, Yong ^a   Crane, Denis I ^b   Florin, Timothy H ^a,c   McGuckin, Michael A ^a,c,e  

^a MATER MEDICAL RESEARCH INSTITUTE   (Australia)

^b GRIFFITH UNIVERSITY   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d UNIVERSITY OF TASMANIA   (Australia)

^e TRANSLATIONAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CHAPERONE; DEXAMETHASONE; GAMMA INTERFERON; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; MESSENGER RNA; MIFEPRISTONE; MUCIN 2; PROTEIN PRECURSOR; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; TUNICAMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CELLULAR DISTRIBUTION; COLITIS; COLON CARCINOMA; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENTERITIS; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; GLYCOSYLATION; GOBLET CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINAL ENDOPLASMIC RETICULUM STRESS; MALE; MESENTERY LYMPH NODE; MISSENSE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN SYNTHESIS; PROTEIN UNFOLDING; SECRETORY CELL; UNFOLDED PROTEIN RESPONSE;

ANIMALS; CALCIUM; CELL LINE, TUMOR; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; EPITHELIAL CELLS; FEMALE; GLUCOCORTICOIDS; GLUCOSE; GLYCOSYLATION; HUMANS; INFLAMMATION; INTESTINES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MUCIN-2; NF-KAPPA B; PROTEIN FOLDING; PROTEOLYSIS; RECEPTORS, GLUCOCORTICOID; UNFOLDED PROTEIN RESPONSE; UP-REGULATION;

EID: 84880650333     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20121268     Document Type: Article

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