메뉴 건너뛰기




Volumn 24, Issue 4, 2013, Pages 339-344

Paraoxonase 1 activities, regulation, and interactions with atherosclerotic lesion

Author keywords

Atherosclerosis; Carotid plaque; Lipids; Paraoxonase

Indexed keywords

ANTIOXIDANT; ARYLDIALKYLPHOSPHATASE 1; FATTY ACID; FLAVONOID; GLABRIDIN; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; METAL; PHOSPHOLIPID; POLYPHENOL; QUERCETIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SURFACTANT;

EID: 84880624365     PISSN: 09579672     EISSN: 14736535     Source Type: Journal    
DOI: 10.1097/MOL.0b013e32835ffcfd     Document Type: Review
Times cited : (76)

References (48)
  • 1
    • 0029905656 scopus 로고    scopus 로고
    • Structural and functional diversity of paraoxonases
    • La Du BN. Structural and functional diversity of paraoxonases. Nat Med 1996; 2:1186-1187.
    • (1996) Nat Med , vol.2 , pp. 1186-1187
    • La Du, B.N.1
  • 2
    • 0030753875 scopus 로고    scopus 로고
    • Increased immunolocalization of paraoxonase, clusterin, and apolipoprotein A-I in the human artery wall with the progression of atherosclerosis
    • Mackness B, Hunt R, Durrington PN, Mackness MI. Increased immunolocalization of paraoxonase, clusterin, and apolipoprotein A-I in the human artery wall with the progression of atherosclerosis. Arterioscler Thromb Vasc Biol 1997; 17:1233-1238.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1233-1238
    • MacKness, B.1    Hunt, R.2    Durrington, P.N.3    MacKness, M.I.4
  • 3
    • 84880589969 scopus 로고    scopus 로고
    • Increased levels of human carotid lesion linoleic acid hydroperoxide in symptomatic and asymptomatic patients is inversely correlated with serum HDL and paraoxonase 1 activity
    • Cohen E, Aviram M, Khatib S, et al. Increased levels of human carotid lesion linoleic acid hydroperoxide in symptomatic and asymptomatic patients is inversely correlated with serum HDL and paraoxonase 1 activity. J Lipids 2012; 2012:762560.
    • (2012) J Lipids , vol.2012 , pp. 762560
    • Cohen, E.1    Aviram, M.2    Khatib, S.3
  • 4
    • 84858444492 scopus 로고    scopus 로고
    • Paraoxonase activity in healthy, diabetic, and hemodialysis patients
    • Gbandjaba NY, Ghalim N, Hassar M, et al. Paraoxonase activity in healthy, diabetic, and hemodialysis patients. Clin Biochem 2012; 45:470-474.
    • (2012) Clin Biochem , vol.45 , pp. 470-474
    • Gbandjaba, N.Y.1    Ghalim, N.2    Hassar, M.3
  • 5
    • 78650815261 scopus 로고    scopus 로고
    • The three-gene paraoxonase family: Physiologic roles, actions and regulation
    • Levy E, Precourt LP, Amre D, et al. The three-gene paraoxonase family: physiologic roles, actions and regulation. Atherosclerosis 2011; 214:20-36.
    • (2011) Atherosclerosis , vol.214 , pp. 20-36
    • Levy, E.1    Precourt, L.P.2    Amre, D.3
  • 6
    • 0034617073 scopus 로고    scopus 로고
    • Homocysteine thiolactone and protein homocysteinylation in human endothelial cells: Implications for atherosclerosis
    • Jakubowski H, Zhang L, Bardeguez A, Aviv A. Homocysteine thiolactone and protein homocysteinylation in human endothelial cells: implications for atherosclerosis. Circ Res 2000; 87:45-51.
    • (2000) Circ Res , vol.87 , pp. 45-51
    • Jakubowski, H.1    Zhang, L.2    Bardeguez, A.3    Aviv, A.4
  • 7
  • 8
    • 84874075706 scopus 로고    scopus 로고
    • High-density lipoprotein impedes glycation of low-density lipoprotein
    • Younis NN, Soran H, Charlton-Menys V, et al. High-density lipoprotein impedes glycation of low-density lipoprotein. Diab Vasc Dis Res 2013; 10:152-160.
    • (2013) Diab Vasc Dis Res , vol.10 , pp. 152-160
    • Younis, N.N.1    Soran, H.2    Charlton-Menys, V.3
  • 9
    • 0037341390 scopus 로고    scopus 로고
    • Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: Possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation
    • Rozenberg O, Shih DM, Aviram M. Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation. Arterioscler Thromb Vasc Biol 2003; 23:461-467.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 461-467
    • Rozenberg, O.1    Shih, D.M.2    Aviram, M.3
  • 10
    • 33646202459 scopus 로고    scopus 로고
    • The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux
    • Rosenblat M, Gaidukov L, Khersonsky O, et al. The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux. J Biol Chem 2006; 281:7657-7665.
    • (2006) J Biol Chem , vol.281 , pp. 7657-7665
    • Rosenblat, M.1    Gaidukov, L.2    Khersonsky, O.3
  • 11
    • 0034738140 scopus 로고    scopus 로고
    • Human serum paraoxonases (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions: PON1 esterase and peroxidase-like activities
    • Aviram M, Hardak E, Vaya J, et al. Human serum paraoxonases (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions: PON1 esterase and peroxidase-like activities. Circulation 2000; 101:2510-2517.
    • (2000) Circulation , vol.101 , pp. 2510-2517
    • Aviram, M.1    Hardak, E.2    Vaya, J.3
  • 12
    • 52049103174 scopus 로고    scopus 로고
    • Macrophage paraoxonase 1 (PON1) binding sites
    • Efrat M, Aviram M. Macrophage paraoxonase 1 (PON1) binding sites. Biochem Biophys Res Commun 2008; 376:105-110.
    • (2008) Biochem Biophys Res Commun , vol.376 , pp. 105-110
    • Efrat, M.1    Aviram, M.2
  • 13
    • 78650703449 scopus 로고    scopus 로고
    • HDL-associated paraoxonase-1 can redistribute to cell membranes and influence sensitivity to oxidative stress
    • Deakin SP, Bioletto S, Bochaton-Piallat ML, James RW. HDL-associated paraoxonase-1 can redistribute to cell membranes and influence sensitivity to oxidative stress. Free Radic Biol Med 2011; 50:102-109.
    • (2011) Free Radic Biol Med , vol.50 , pp. 102-109
    • Deakin, S.P.1    Bioletto, S.2    Bochaton-Piallat, M.L.3    James, R.W.4
  • 14
    • 84859001444 scopus 로고    scopus 로고
    • Purified human paraoxonase-1 interacts with plasma membrane lipid rafts and mediates cholesterol efflux from macrophages
    • Berrougui H, Loued S, Khalil A. Purified human paraoxonase-1 interacts with plasma membrane lipid rafts and mediates cholesterol efflux from macrophages. Free Radic Biol Med 2012; 52:1372-1381.
    • (2012) Free Radic Biol Med , vol.52 , pp. 1372-1381
    • Berrougui, H.1    Loued, S.2    Khalil, A.3
  • 15
    • 13844256208 scopus 로고    scopus 로고
    • Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: A possible role for lysophosphatidylcholine
    • Rosenblat M, Vaya J, Shih D, Aviram M. Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine. Atherosclerosis 2005; 179:69-77.
    • (2005) Atherosclerosis , vol.179 , pp. 69-77
    • Rosenblat, M.1    Vaya, J.2    Shih, D.3    Aviram, M.4
  • 16
    • 63849176055 scopus 로고    scopus 로고
    • Novel serum paraoxonase activity assays are associated with coronary artery disease
    • Martinelli N, Girelli D, Olivieri O, et al. Novel serum paraoxonase activity assays are associated with coronary artery disease. Clin Chem Lab Med 2009; 47:432-440.
    • (2009) Clin Chem Lab Med , vol.47 , pp. 432-440
    • Martinelli, N.1    Girelli, D.2    Olivieri, O.3
  • 17
    • 77952952772 scopus 로고    scopus 로고
    • HDL-paraoxonase and membrane lipid peroxidation: A comparison between healthy and obese subjects
    • Ferretti G, Bacchetti T, Masciangelo S, Bicchiega V. HDL-paraoxonase and membrane lipid peroxidation: a comparison between healthy and obese subjects. Obesity (Silver Spring) 2010; 18:1079-1084.
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 1079-1084
    • Ferretti, G.1    Bacchetti, T.2    Masciangelo, S.3    Bicchiega, V.4
  • 18
    • 0036924276 scopus 로고    scopus 로고
    • Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia
    • Paragh G, Balla P, Katona E, et al. Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia. Eur Arch Psychiatry Clin Neurosci 2002; 252:63-67.
    • (2002) Eur Arch Psychiatry Clin Neurosci , vol.252 , pp. 63-67
    • Paragh, G.1    Balla, P.2    Katona, E.3
  • 19
    • 60249083427 scopus 로고    scopus 로고
    • Oxidative inactivation of lactonase activity of purified human paraoxonase 1 (PON1)
    • Nguyen SD, Hung ND, Cheon-Ho P, et al. Oxidative inactivation of lactonase activity of purified human paraoxonase 1 (PON1). Biochim Biophys Acta 2009; 1790:155-160.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 155-160
    • Nguyen, S.D.1    Hung, N.D.2    Cheon-Ho, P.3
  • 20
    • 0032921557 scopus 로고    scopus 로고
    • Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants
    • Aviram M, Rosenblat M, Billecke S, et al. Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants. Free Radic Biol Med 1999; 26:892-904.
    • (1999) Free Radic Biol Med , vol.26 , pp. 892-904
    • Aviram, M.1    Rosenblat, M.2    Billecke, S.3
  • 21
    • 33750508148 scopus 로고    scopus 로고
    • S-Glutathionylation regulates HDL-associated paraoxonase 1 (PON1) activity
    • Rozenberg O, Aviram M. S-Glutathionylation regulates HDL-associated paraoxonase 1 (PON1) activity. Biochem Biophys Res Commun 2006; 351:492-498.
    • (2006) Biochem Biophys Res Commun , vol.351 , pp. 492-498
    • Rozenberg, O.1    Aviram, M.2
  • 22
    • 78149497677 scopus 로고    scopus 로고
    • Effect of nongenetic factors on paraoxonase 1 activity in patients undergoing hemodialysis
    • Rajkovic MG, Rumora L, Juretic D, et al. Effect of nongenetic factors on paraoxonase 1 activity in patients undergoing hemodialysis. Clin Biochem 2010; 43:1375-1380.
    • (2010) Clin Biochem , vol.43 , pp. 1375-1380
    • Rajkovic, M.G.1    Rumora, L.2    Juretic, D.3
  • 23
    • 2342569704 scopus 로고    scopus 로고
    • Structure and evolution of the serum paraoxonase family of detoxifying and antiatherosclerotic enzymes
    • Harel M, Aharoni A, Gaidukov L, et al. Structure and evolution of the serum paraoxonase family of detoxifying and antiatherosclerotic enzymes. Nat Struct Mol Biol 2004; 11:412-419.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 412-419
    • Harel, M.1    Aharoni, A.2    Gaidukov, L.3
  • 24
    • 84858757313 scopus 로고    scopus 로고
    • Atherosclerosis: Cell biology and lipoproteins: Paraoxonases protect against atherosclerosis and diabetes development
    • Aviram M. Atherosclerosis: cell biology and lipoproteins: paraoxonases protect against atherosclerosis and diabetes development. Curr Opin Lipidol 2012; 23:169-171.
    • (2012) Curr Opin Lipidol , vol.23 , pp. 169-171
    • Aviram, M.1
  • 25
    • 58549107794 scopus 로고    scopus 로고
    • Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: In vitro and in vivo studies
    • Efrat M, Rosenblat M, Mahmood S, et al. Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies. Atherosclerosis 2009; 202:461-469.
    • (2009) Atherosclerosis , vol.202 , pp. 461-469
    • Efrat, M.1    Rosenblat, M.2    Mahmood, S.3
  • 26
    • 58949085340 scopus 로고    scopus 로고
    • Quercetin up-regulates paraoxonase 1 gene expression with concomitant protection against LDL oxidation
    • Gong M, Garige M, Varatharajalu R, et al. Quercetin up-regulates paraoxonase 1 gene expression with concomitant protection against LDL oxidation. Biochem Biophys Res Commun 2009; 379:1001-1004.
    • (2009) Biochem Biophys Res Commun , vol.379 , pp. 1001-1004
    • Gong, M.1    Garige, M.2    Varatharajalu, R.3
  • 27
    • 77954304386 scopus 로고    scopus 로고
    • Effect of quercetin on paraoxonase 1 activity: Studies in cultured cells, mice and humans
    • Boesch-Saadatmandi C, Egert S, Schrader C, et al. Effect of quercetin on paraoxonase 1 activity: studies in cultured cells, mice and humans. J Physiol Pharmacol 2010; 61:99-105.
    • (2010) J Physiol Pharmacol , vol.61 , pp. 99-105
    • Boesch-Saadatmandi, C.1    Egert, S.2    Schrader, C.3
  • 28
    • 77349101573 scopus 로고    scopus 로고
    • Pomegranate juice polyphenols increase recombinant paraoxonase-1 binding to high-density lipoprotein: Studies in vitro and in diabetic patients
    • Fuhrman B, Volkova N, Aviram M. Pomegranate juice polyphenols increase recombinant paraoxonase-1 binding to high-density lipoprotein: studies in vitro and in diabetic patients. Nutrition 2010; 26:359-366.
    • (2010) Nutrition , vol.26 , pp. 359-366
    • Fuhrman, B.1    Volkova, N.2    Aviram, M.3
  • 29
    • 73449098892 scopus 로고    scopus 로고
    • Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: A role for PPAR-gamma pathway
    • Khateeb J, Gantman A, Kreitenberg AJ, et al. Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: a role for PPAR-gamma pathway. Atherosclerosis 2010; 208:119-125.
    • (2010) Atherosclerosis , vol.208 , pp. 119-125
    • Khateeb, J.1    Gantman, A.2    Kreitenberg, A.J.3
  • 30
    • 77956231001 scopus 로고    scopus 로고
    • Pomegranate juice (PJ) consumption antioxidative properties on mouse macrophages, but not PJ beneficial effects on macrophage cholesterol and triglyceride metabolism, are mediated via PJ-induced stimulation of macrophage PON2
    • Rosenblat M, Volkova N, Aviram M. Pomegranate juice (PJ) consumption antioxidative properties on mouse macrophages, but not PJ beneficial effects on macrophage cholesterol and triglyceride metabolism, are mediated via PJ-induced stimulation of macrophage PON2. Atherosclerosis 2010; 212:86-92.
    • (2010) Atherosclerosis , vol.212 , pp. 86-92
    • Rosenblat, M.1    Volkova, N.2    Aviram, M.3
  • 31
    • 80055007728 scopus 로고    scopus 로고
    • Paraoxonase 1 (PON1) inhibits monocyte-to-macrophage differentiation
    • Rosenblat M, Volkova N, Ward J, Aviram M. Paraoxonase 1 (PON1) inhibits monocyte-to-macrophage differentiation. Atherosclerosis 2011; 219:49-56.
    • (2011) Atherosclerosis , vol.219 , pp. 49-56
    • Rosenblat, M.1    Volkova, N.2    Ward, J.3    Aviram, M.4
  • 32
    • 78149429670 scopus 로고    scopus 로고
    • Paraoxonase 1 interactions with atherosclerotic lesions and arterial macrophages protect against foam cell formation and atherosclerosis development
    • Tavori H, Rosenblat M, Vaya J, Aviram M. Paraoxonase 1 interactions with atherosclerotic lesions and arterial macrophages protect against foam cell formation and atherosclerosis development. Clin Lipidol 2010; 5:685-697.
    • (2010) Clin Lipidol , vol.5 , pp. 685-697
    • Tavori, H.1    Rosenblat, M.2    Vaya, J.3    Aviram, M.4
  • 33
    • 78650687313 scopus 로고    scopus 로고
    • Human carotid lesion linoleic acid hydroperoxide inhibits paraoxonase 1 (PON1) activity via reaction with PON1 free sulfhydryl cysteine 284
    • Tavori H, Aviram M, Khatib S, et al. Human carotid lesion linoleic acid hydroperoxide inhibits paraoxonase 1 (PON1) activity via reaction with PON1 free sulfhydryl cysteine 284. Free Radic Biol Med 2011; 50:148-156.
    • (2011) Free Radic Biol Med , vol.50 , pp. 148-156
    • Tavori, H.1    Aviram, M.2    Khatib, S.3
  • 34
    • 84859618901 scopus 로고    scopus 로고
    • Glabridin protects paraoxonase 1 from linoleic acid hydroperoxide inhibition via specific interaction: A fluorescence-quenching study
    • Atrahimovich D, Vaya J, Tavori H, Khatib S. Glabridin protects paraoxonase 1 from linoleic acid hydroperoxide inhibition via specific interaction: a fluorescence-quenching study. J Agric Food Chem 2012; 60:3679-3685.
    • (2012) J Agric Food Chem , vol.60 , pp. 3679-3685
    • Atrahimovich, D.1    Vaya, J.2    Tavori, H.3    Khatib, S.4
  • 35
    • 0028925078 scopus 로고
    • Atherosclerosis: Basic mechanisms. Oxidation, inflammation, and genetics
    • Berliner JA, Navab M, Fogelman AM, et al. Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics. Circulation 1995; 91:2488-2496.
    • (1995) Circulation , vol.91 , pp. 2488-2496
    • Berliner, J.A.1    Navab, M.2    Fogelman, A.M.3
  • 36
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis: The road ahead
    • Glass CK, Witztum JL. Atherosclerosis: the road ahead. Cell 2001; 104:503-516.
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 37
    • 79551664540 scopus 로고    scopus 로고
    • Immunohistochemical analysis of paraoxonases-1 and 3 in human atheromatous plaques
    • Marsillach J, Camps J, Beltran-Debon R, et al. Immunohistochemical analysis of paraoxonases-1 and 3 in human atheromatous plaques. Eur J Clin Invest 2011; 41:308-314.
    • (2011) Eur J Clin Invest , vol.41 , pp. 308-314
    • Marsillach, J.1    Camps, J.2    Beltran-Debon, R.3
  • 38
    • 77951879344 scopus 로고    scopus 로고
    • Composition of carotid atherosclerotic plaque is associated with cardiovascular outcome: A prognostic study
    • Hellings WE, Peeters W, Moll FL, et al. Composition of carotid atherosclerotic plaque is associated with cardiovascular outcome: a prognostic study. Circulation 2010; 121:1941-1950.
    • (2010) Circulation , vol.121 , pp. 1941-1950
    • Hellings, W.E.1    Peeters, W.2    Moll, F.L.3
  • 39
    • 80052783908 scopus 로고    scopus 로고
    • Comparative lipidomics profiling of human atherosclerotic plaques
    • Stegemann C, Drozdov I, Shalhoub J, et al. Comparative lipidomics profiling of human atherosclerotic plaques. Circ Cardiovasc Genet 2011; 4:232-242.
    • (2011) Circ Cardiovasc Genet , vol.4 , pp. 232-242
    • Stegemann, C.1    Drozdov, I.2    Shalhoub, J.3
  • 40
    • 80054068135 scopus 로고    scopus 로고
    • Novel serum biomarkers in carotid artery stenosis: Useful to identify the vulnerable plaque?
    • Hermus L, Schuitemaker JH, Tio RA, et al. Novel serum biomarkers in carotid artery stenosis: useful to identify the vulnerable plaque? Clin Biochem 2011; 44:1292-1298.
    • (2011) Clin Biochem , vol.44 , pp. 1292-1298
    • Hermus, L.1    Schuitemaker, J.H.2    Tio, R.A.3
  • 41
    • 84861200609 scopus 로고    scopus 로고
    • Asymptomatic carotid artery stenosis: Identification of subgroups with different underlying plaque characteristics
    • van Lammeren GW, den Hartog AG, Pasterkamp G, et al. Asymptomatic carotid artery stenosis: identification of subgroups with different underlying plaque characteristics. Eur J Vasc Endovasc Surg 2012; 43:632-636.
    • (2012) Eur J Vasc Endovasc Surg , vol.43 , pp. 632-636
    • Van Lammeren, G.W.1    Den Hartog, A.G.2    Pasterkamp, G.3
  • 42
    • 79960490052 scopus 로고    scopus 로고
    • Adipocyte fatty acid binding protein in atherosclerotic plaques is associated with local vulnerability and is predictive for the occurrence of adverse cardiovascular events
    • Peeters W, de Kleijn DP, Vink A, et al. Adipocyte fatty acid binding protein in atherosclerotic plaques is associated with local vulnerability and is predictive for the occurrence of adverse cardiovascular events. Eur Heart J 2011; 32:1758-1768.
    • (2011) Eur Heart J , vol.32 , pp. 1758-1768
    • Peeters, W.1    De Kleijn, D.P.2    Vink, A.3
  • 43
    • 77958461205 scopus 로고    scopus 로고
    • Carotid plaque formation and serum biomarkers
    • Hermus L, Lefrandt JD, Tio RA, et al. Carotid plaque formation and serum biomarkers. Atherosclerosis 2010; 213:21-29.
    • (2010) Atherosclerosis , vol.213 , pp. 21-29
    • Hermus, L.1    Lefrandt, J.D.2    Tio, R.A.3
  • 44
    • 84863802283 scopus 로고    scopus 로고
    • Myeloperoxidase-derived chlorinating species induce protein carbamylation through decomposition of thiocyanate and urea: Novel pathways generating dysfunctional high-density lipoprotein
    • Holzer M, Zangger K, El-Gamal D, et al. Myeloperoxidase-derived chlorinating species induce protein carbamylation through decomposition of thiocyanate and urea: novel pathways generating dysfunctional high-density lipoprotein. Antioxid Redox Signal 2012; 17:1043-1052.
    • (2012) Antioxid Redox Signal , vol.17 , pp. 1043-1052
    • Holzer, M.1    Zangger, K.2    El-Gamal, D.3
  • 45
    • 79957495316 scopus 로고    scopus 로고
    • Protein carbamylation renders high-density lipoprotein dysfunctional
    • Holzer M, Gauster M, Pfeifer T, et al. Protein carbamylation renders high-density lipoprotein dysfunctional. Antioxid Redox Signal 2011; 14:2337-2346.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 2337-2346
    • Holzer, M.1    Gauster, M.2    Pfeifer, T.3
  • 46
    • 77953810664 scopus 로고    scopus 로고
    • Relationship between paraoxonase-1 activity, carotid intima-media thickness and arterial stiffness in hypertensive patients
    • Yang WI, Lee SH, Ko YG, et al. Relationship between paraoxonase-1 activity, carotid intima-media thickness and arterial stiffness in hypertensive patients. J Hum Hypertens 2010; 24:492-494.
    • (2010) J Hum Hypertens , vol.24 , pp. 492-494
    • Yang, W.I.1    Lee, S.H.2    Ko, Y.G.3
  • 47
    • 79957945207 scopus 로고    scopus 로고
    • Paraoxonase 1 protects macrophages from atherogenicity of a specific triglyceride isolated from human carotid lesion
    • Tavori H, Aviram M, Khatib S, et al. Paraoxonase 1 protects macrophages from atherogenicity of a specific triglyceride isolated from human carotid lesion. Free Radic Biol Med 2011; 51:234-242.
    • (2011) Free Radic Biol Med , vol.51 , pp. 234-242
    • Tavori, H.1    Aviram, M.2    Khatib, S.3
  • 48
    • 0032522985 scopus 로고    scopus 로고
    • Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions A possible peroxidative role for paraoxonase
    • Aviram M, Rosenblat M, Bisgaier CL, et al. Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions A possible peroxidative role for paraoxonase. J Clin Invest 1998; 101:1581-1590.
    • (1998) J Clin Invest , vol.101 , pp. 1581-1590
    • Aviram, M.1    Rosenblat, M.2    Bisgaier, C.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.