메뉴 건너뛰기




Volumn 1790, Issue 3, 2009, Pages 155-160

Oxidative inactivation of lactonase activity of purified human paraoxonase 1 (PON1)

Author keywords

Antioxidant; Arylesterase; Lactonase; Oxidative inactivation; Paraoxonase; Reactive oxygen specie

Indexed keywords

ARYLDIALKYLPHOSPHATASE 1; ARYLESTERASE; ASCORBIC ACID; CATALASE; CUPRIC ION; FERROUS ION; GLUCONOLACTONASE; HYDROXYL RADICAL; OLEIC ACID; PHOSPHATIDYLCHOLINE;

EID: 60249083427     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2008.11.009     Document Type: Article
Times cited : (34)

References (41)
  • 1
    • 0029905656 scopus 로고    scopus 로고
    • Structural and functional diversity of paraoxonases
    • La Du B.N. Structural and functional diversity of paraoxonases. Nat. Med. 2 (1996) 1186-1187
    • (1996) Nat. Med. , vol.2 , pp. 1186-1187
    • La Du, B.N.1
  • 4
    • 0037639963 scopus 로고    scopus 로고
    • Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism
    • Costa L.G., Cole T.B., Jarvik G.P., and Furlong C.E. Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. Annu. Rev. Med. 54 (2003) 371-392
    • (2003) Annu. Rev. Med. , vol.54 , pp. 371-392
    • Costa, L.G.1    Cole, T.B.2    Jarvik, G.P.3    Furlong, C.E.4
  • 6
    • 0037443799 scopus 로고    scopus 로고
    • Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress: studies in PON1-knockout mice
    • Rozenberg O., Rosenblat M., Coleman R., Shih D.M., and Aviram M. Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress: studies in PON1-knockout mice. Free Radic. Biol. Med. 34 (2003) 774-784
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 774-784
    • Rozenberg, O.1    Rosenblat, M.2    Coleman, R.3    Shih, D.M.4    Aviram, M.5
  • 7
    • 33745964245 scopus 로고    scopus 로고
    • Human paraoxonase-1 overexpression inhibits atherosclerosis in a mouse model of metabolic syndrome
    • Mackness B., Quarck R., Verreth W., Mackness M., and Holvoet P. Human paraoxonase-1 overexpression inhibits atherosclerosis in a mouse model of metabolic syndrome. Arterioscler. Thromb. Vasc. Biol. 26 (2006) 1545-1550
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1545-1550
    • Mackness, B.1    Quarck, R.2    Verreth, W.3    Mackness, M.4    Holvoet, P.5
  • 8
    • 20444419056 scopus 로고    scopus 로고
    • Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice
    • Rozenberg O., Shih D.M., and Aviram M. Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice. Atherosclerosis 181 (2005) 9-18
    • (2005) Atherosclerosis , vol.181 , pp. 9-18
    • Rozenberg, O.1    Shih, D.M.2    Aviram, M.3
  • 10
    • 13844256208 scopus 로고    scopus 로고
    • Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine
    • Rosenblat M., Vaya J., Shih D., and Aviram M. Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine. Atherosclerosis 179 (2005) 69-77
    • (2005) Atherosclerosis , vol.179 , pp. 69-77
    • Rosenblat, M.1    Vaya, J.2    Shih, D.3    Aviram, M.4
  • 12
    • 0034721761 scopus 로고    scopus 로고
    • Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation
    • Draganov D.I., Stetson P.L., Watson C.E., Billecke S.S., and La Du B.N. Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation. J. Biol. Chem. 275 (2000) 33435-33442
    • (2000) J. Biol. Chem. , vol.275 , pp. 33435-33442
    • Draganov, D.I.1    Stetson, P.L.2    Watson, C.E.3    Billecke, S.S.4    La Du, B.N.5
  • 13
    • 17644367506 scopus 로고    scopus 로고
    • Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase
    • Khersonsky O., and Tawfik D.S. Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase. Biochemistry 44 (2005) 6371-6382
    • (2005) Biochemistry , vol.44 , pp. 6371-6382
    • Khersonsky, O.1    Tawfik, D.S.2
  • 14
    • 0042261695 scopus 로고    scopus 로고
    • Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3
    • Teiber J.F., Draganov D.I., and La Du B.N. Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3. Biochem. Pharmacol. 66 (2003) 887-896
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 887-896
    • Teiber, J.F.1    Draganov, D.I.2    La Du, B.N.3
  • 15
    • 0347635518 scopus 로고    scopus 로고
    • Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization
    • Aharoni A., Gaidukov L., Yagur S., Toker L., Silman I., and Tawfik D.S. Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization. Proc. Natl. Acad. Sci. U. S. A 101 (2004) 482-487
    • (2004) Proc. Natl. Acad. Sci. U. S. A , vol.101 , pp. 482-487
    • Aharoni, A.1    Gaidukov, L.2    Yagur, S.3    Toker, L.4    Silman, I.5    Tawfik, D.S.6
  • 17
    • 21244491480 scopus 로고    scopus 로고
    • Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities
    • Draganov D.I., Teiber J.F., Speelman A., Osawa Y., Sunahara R., and La Du B.N. Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. J. Lipid Res. 46 (2005) 1239-1247
    • (2005) J. Lipid Res. , vol.46 , pp. 1239-1247
    • Draganov, D.I.1    Teiber, J.F.2    Speelman, A.3    Osawa, Y.4    Sunahara, R.5    La Du, B.N.6
  • 18
    • 0344875683 scopus 로고    scopus 로고
    • Oxidative inactivation of paraoxonase1, an antioxidant protein and its effect on antioxidant action
    • Nguyen S.D., and Sok D.E. Oxidative inactivation of paraoxonase1, an antioxidant protein and its effect on antioxidant action. Free Radic. Res. 37 (2003) 1319-1330
    • (2003) Free Radic. Res. , vol.37 , pp. 1319-1330
    • Nguyen, S.D.1    Sok, D.E.2
  • 19
    • 0842281272 scopus 로고    scopus 로고
    • Copper ions and hypochlorite are mainly responsible for oxidative inactivation of paraoxon-hydrolyzing activity in human high density lipoprotein
    • Nguyen S.D., Kim J.R., Kim M.R., Jung T.S., and Soka D.E. Copper ions and hypochlorite are mainly responsible for oxidative inactivation of paraoxon-hydrolyzing activity in human high density lipoprotein. Toxicol. Lett. 147 (2004) 201-208
    • (2004) Toxicol. Lett. , vol.147 , pp. 201-208
    • Nguyen, S.D.1    Kim, J.R.2    Kim, M.R.3    Jung, T.S.4    Soka, D.E.5
  • 21
    • 0142138852 scopus 로고    scopus 로고
    • Beneficial effect of oleoylated lipids on paraoxonase 1: protection against oxidative inactivation and stabilization
    • Nguyen S.D., and Sok D.E. Beneficial effect of oleoylated lipids on paraoxonase 1: protection against oxidative inactivation and stabilization. Biochem. J. 375 (2003) 275-285
    • (2003) Biochem. J. , vol.375 , pp. 275-285
    • Nguyen, S.D.1    Sok, D.E.2
  • 22
    • 0021070710 scopus 로고
    • The human serum paraoxonase/arylesterase polymorphism
    • Eckerson H.W., Wyte C.M., and La Du B.N. The human serum paraoxonase/arylesterase polymorphism. Am. J. Hum. Genet. 35 (1983) 1126-1138
    • (1983) Am. J. Hum. Genet. , vol.35 , pp. 1126-1138
    • Eckerson, H.W.1    Wyte, C.M.2    La Du, B.N.3
  • 23
    • 0026096803 scopus 로고
    • Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities
    • Gan K.N., Smolen A., Eckerson H.W., and La Du B.N. Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities. Drug Metab. Dispos. 19 (1991) 100-106
    • (1991) Drug Metab. Dispos. , vol.19 , pp. 100-106
    • Gan, K.N.1    Smolen, A.2    Eckerson, H.W.3    La Du, B.N.4
  • 24
    • 30444432098 scopus 로고    scopus 로고
    • Chromogenic and fluorogenic assays for the lactonase activity of serum paraoxonases
    • Khersonsky O., and Tawfik D.S. Chromogenic and fluorogenic assays for the lactonase activity of serum paraoxonases. ChemBioChem 7 (2006) 49-53
    • (2006) ChemBioChem , vol.7 , pp. 49-53
    • Khersonsky, O.1    Tawfik, D.S.2
  • 25
    • 33646202459 scopus 로고    scopus 로고
    • The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux
    • Rosenblat M., Gaidukov L., Khersonsky O., Vaya J., Oren R., Tawfik D.S., and Aviram M. The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux. J. Biol. Chem. 281 (2006) 7657-7665
    • (2006) J. Biol. Chem. , vol.281 , pp. 7657-7665
    • Rosenblat, M.1    Gaidukov, L.2    Khersonsky, O.3    Vaya, J.4    Oren, R.5    Tawfik, D.S.6    Aviram, M.7
  • 26
    • 33644759340 scopus 로고    scopus 로고
    • Broad-spectrum antioxidant peptides derived from His residue-containing sequences present in human paraoxonase 1
    • Nguyen S.D., Jeong T.S., Kim M.R., and Sok D.E. Broad-spectrum antioxidant peptides derived from His residue-containing sequences present in human paraoxonase 1. Free Radic. Res. 40 (2006) 349-358
    • (2006) Free Radic. Res. , vol.40 , pp. 349-358
    • Nguyen, S.D.1    Jeong, T.S.2    Kim, M.R.3    Sok, D.E.4
  • 27
    • 0031816430 scopus 로고    scopus 로고
    • Calcium binding by human and rabbit serum paraoxonases. Structural stability and enzymatic activity
    • Kuo C.L., and La Du B.N. Calcium binding by human and rabbit serum paraoxonases. Structural stability and enzymatic activity. Drug Metab. Dispos. 26 (1998) 653-660
    • (1998) Drug Metab. Dispos. , vol.26 , pp. 653-660
    • Kuo, C.L.1    La Du, B.N.2
  • 28
    • 0025239795 scopus 로고
    • The physiological role of zinc as an antioxidant
    • Bray T.M., and Bettger W.J. The physiological role of zinc as an antioxidant. Free Radic. Biol. Med. 8 (1990) 281-291
    • (1990) Free Radic. Biol. Med. , vol.8 , pp. 281-291
    • Bray, T.M.1    Bettger, W.J.2
  • 29
    • 24344460308 scopus 로고    scopus 로고
    • High affinity, stability, and lactonase activity of serum paraoxonase PON1 anchored on HDL with ApoA-I
    • Gaidukov L., and Tawfik D.S. High affinity, stability, and lactonase activity of serum paraoxonase PON1 anchored on HDL with ApoA-I. Biochemistry 44 (2005) 11843-11854
    • (2005) Biochemistry , vol.44 , pp. 11843-11854
    • Gaidukov, L.1    Tawfik, D.S.2
  • 30
    • 0035997049 scopus 로고    scopus 로고
    • Structural transitions in short-chain lipid assemblies studied by (31)P-NMR spectroscopy
    • Kleinschmidt J.H., and Tamm L.K. Structural transitions in short-chain lipid assemblies studied by (31)P-NMR spectroscopy. Biophys. J. 83 (2002) 994-1003
    • (2002) Biophys. J. , vol.83 , pp. 994-1003
    • Kleinschmidt, J.H.1    Tamm, L.K.2
  • 33
    • 5344238178 scopus 로고    scopus 로고
    • Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development
    • Aviram M., and Rosenblat M. Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development. Free Radic. Biol. Med. 37 (2004) 1304-1316
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 1304-1316
    • Aviram, M.1    Rosenblat, M.2
  • 34
    • 43049162677 scopus 로고    scopus 로고
    • Paraoxonase 1 (PON1) attenuates diabetes development in mice through its antioxidative properties
    • Rozenberg O., Shiner M., Aviram M., and Hayek T. Paraoxonase 1 (PON1) attenuates diabetes development in mice through its antioxidative properties. Free Radic. Biol. Med. 44 (2008) 1951-1959
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 1951-1959
    • Rozenberg, O.1    Shiner, M.2    Aviram, M.3    Hayek, T.4
  • 35
    • 0025911829 scopus 로고
    • Metal-catalyzed oxidation of proteins. Physiological consequences
    • Stadtman E.R., and Oliver C.N. Metal-catalyzed oxidation of proteins. Physiological consequences. J. Biol. Chem. 266 (1991) 2005-2008
    • (1991) J. Biol. Chem. , vol.266 , pp. 2005-2008
    • Stadtman, E.R.1    Oliver, C.N.2
  • 36
    • 33744511920 scopus 로고    scopus 로고
    • Paraoxonase 1 (PON1) is a more potent antioxidant and stimulant of macrophage cholesterol efflux, when present in HDL than in lipoprotein-deficient serum: relevance to diabetes
    • Rosenblat M., Karry R., and Aviram M. Paraoxonase 1 (PON1) is a more potent antioxidant and stimulant of macrophage cholesterol efflux, when present in HDL than in lipoprotein-deficient serum: relevance to diabetes. Atherosclerosis 187 (2006) 74-81
    • (2006) Atherosclerosis , vol.187 , pp. 74-81
    • Rosenblat, M.1    Karry, R.2    Aviram, M.3
  • 40
    • 33747038067 scopus 로고    scopus 로고
    • Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus
    • Lakshman M.R., Gottipati C.S., Narasimhan S.J., Munoz J., Marmillot P., and Nylen E.S. Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus. Metabolism 55 (2006) 1201-1206
    • (2006) Metabolism , vol.55 , pp. 1201-1206
    • Lakshman, M.R.1    Gottipati, C.S.2    Narasimhan, S.J.3    Munoz, J.4    Marmillot, P.5    Nylen, E.S.6
  • 41
    • 33645238117 scopus 로고    scopus 로고
    • High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism
    • Pasca S.P., Nemes B., Vlase L., Gagyi C.E., Dronca E., Miu A.C., and Dronca M. High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism. Life Sci. 78 (2006) 2244-2248
    • (2006) Life Sci. , vol.78 , pp. 2244-2248
    • Pasca, S.P.1    Nemes, B.2    Vlase, L.3    Gagyi, C.E.4    Dronca, E.5    Miu, A.C.6    Dronca, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.