-
1
-
-
0037040274
-
Enzymatically active paraoxonase-1 is located at the external membrane of producing cells and released by a high affinity, saturable, desorption mechanism
-
Deakin S., Leviev I., Gomaraschi M., et al. Enzymatically active paraoxonase-1 is located at the external membrane of producing cells and released by a high affinity, saturable, desorption mechanism. J Biol Chem 277 (2002) 4301-4308
-
(2002)
J Biol Chem
, vol.277
, pp. 4301-4308
-
-
Deakin, S.1
Leviev, I.2
Gomaraschi, M.3
-
2
-
-
33645794037
-
Dietary antioxidants and paraoxonases against LDL oxidation and atherosclerosis development
-
Aviram M., Kaplan M., Rosenblat M., and Fuhrman B. Dietary antioxidants and paraoxonases against LDL oxidation and atherosclerosis development. Handb Exp Pharmacol 170 (2005) 263-300
-
(2005)
Handb Exp Pharmacol
, vol.170
, pp. 263-300
-
-
Aviram, M.1
Kaplan, M.2
Rosenblat, M.3
Fuhrman, B.4
-
3
-
-
0032522985
-
Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase
-
Aviram M., Rosenblat M., Bisgaier C.L., et al. Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. J Clin Invest 101 (1998) 1581-1590
-
(1998)
J Clin Invest
, vol.101
, pp. 1581-1590
-
-
Aviram, M.1
Rosenblat, M.2
Bisgaier, C.L.3
-
4
-
-
20444419056
-
Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice
-
Rozenberg O., Shih D.M., and Aviram M. Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice. Atherosclerosis 181 (2005) 9-18
-
(2005)
Atherosclerosis
, vol.181
, pp. 9-18
-
-
Rozenberg, O.1
Shih, D.M.2
Aviram, M.3
-
5
-
-
0032921557
-
Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants
-
Aviram M., Rosenblat M., Billecke S., et al. Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants. Free Radic Biol Med 26 (1999) 892-904
-
(1999)
Free Radic Biol Med
, vol.26
, pp. 892-904
-
-
Aviram, M.1
Rosenblat, M.2
Billecke, S.3
-
6
-
-
0037443799
-
Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress: studies in PON1-knockout mice
-
Rozenberg O., Rosenblat M., Coleman R., Shih D.M., and Aviram M. Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress: studies in PON1-knockout mice. Free Radic Biol Med 34 (2003) 774-784
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 774-784
-
-
Rozenberg, O.1
Rosenblat, M.2
Coleman, R.3
Shih, D.M.4
Aviram, M.5
-
7
-
-
0032756401
-
Daily moderate alcohol consumption increases serum paraoxonase activity; a diet-controlled, randomised intervention study in middle-aged men
-
van der Gaag M.S., van Tol A., Scheek L.M., et al. Daily moderate alcohol consumption increases serum paraoxonase activity; a diet-controlled, randomised intervention study in middle-aged men. Atherosclerosis 147 (1999) 405-410
-
(1999)
Atherosclerosis
, vol.147
, pp. 405-410
-
-
van der Gaag, M.S.1
van Tol, A.2
Scheek, L.M.3
-
8
-
-
0036341516
-
Vitamin C and E intake is associated with increased paraoxonase activity
-
Jarvik G.P., Tsai N.T., McKinstry L.A., et al. Vitamin C and E intake is associated with increased paraoxonase activity. Arterioscler Thromb Vasc Biol 22 (2002) 1329-1333
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1329-1333
-
-
Jarvik, G.P.1
Tsai, N.T.2
McKinstry, L.A.3
-
9
-
-
0036291008
-
Preservation of paraoxonase activity by wine flavonoids: possible role in protection of LDL from lipid peroxidation
-
Fuhrman B., and Aviram M. Preservation of paraoxonase activity by wine flavonoids: possible role in protection of LDL from lipid peroxidation. Ann N Y Acad Sci 957 (2002) 321-324
-
(2002)
Ann N Y Acad Sci
, vol.957
, pp. 321-324
-
-
Fuhrman, B.1
Aviram, M.2
-
10
-
-
0034013311
-
Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice
-
Aviram M., Dornfeld L., Rosenblat M., et al. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am J Clin Nutr 71 (2000) 1062-1076
-
(2000)
Am J Clin Nutr
, vol.71
, pp. 1062-1076
-
-
Aviram, M.1
Dornfeld, L.2
Rosenblat, M.3
-
11
-
-
0031831615
-
Paraoxonase activity in the serum and hepatic mRNA levels decrease during the acute phase response
-
Feingold K.R., Memon R.A., Moser A.H., and Grunfeld C. Paraoxonase activity in the serum and hepatic mRNA levels decrease during the acute phase response. Atherosclerosis 139 (1998) 307-315
-
(1998)
Atherosclerosis
, vol.139
, pp. 307-315
-
-
Feingold, K.R.1
Memon, R.A.2
Moser, A.H.3
Grunfeld, C.4
-
12
-
-
0242721909
-
Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: a role for sterol regulatory element-binding protein-2
-
Deakin S., Leviev I., Guernier S., and James R.W. Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: a role for sterol regulatory element-binding protein-2. Arterioscler Thromb Vasc Biol 23 (2003) 2083-2089
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 2083-2089
-
-
Deakin, S.1
Leviev, I.2
Guernier, S.3
James, R.W.4
-
13
-
-
10644234025
-
Induction of the paraoxonase-1 gene expression by resveratrol
-
Gouédard C., Barouki R., and Morel Y. Induction of the paraoxonase-1 gene expression by resveratrol. Arterioscler Thromb Vasc Biol 24 (2004) 2378-2383
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 2378-2383
-
-
Gouédard, C.1
Barouki, R.2
Morel, Y.3
-
14
-
-
58949085340
-
Quercetin up-regulates paraoxonase 1 gene expression with concomitant protection against LDL oxidation
-
Gong M., Garige M., Varatharajalu R., et al. Quercetin up-regulates paraoxonase 1 gene expression with concomitant protection against LDL oxidation. Biochem Biophys Res Commun 379 (2009) 1001-1004
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 1001-1004
-
-
Gong, M.1
Garige, M.2
Varatharajalu, R.3
-
15
-
-
2942600176
-
Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism
-
Gouédard C., Barouki R., and Morel Y. Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism. Mol Cell Biol 24 (2004) 5209-5222
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5209-5222
-
-
Gouédard, C.1
Barouki, R.2
Morel, Y.3
-
16
-
-
5644267992
-
Roles of Sp1 and protein kinase C in regulation of human serum paraoxonase 1 (PON1) gene transcription in HepG2 cells
-
Osaki F., Ikeda Y., Suehiro T., et al. Roles of Sp1 and protein kinase C in regulation of human serum paraoxonase 1 (PON1) gene transcription in HepG2 cells. Atherosclerosis 176 (2004) 279-287
-
(2004)
Atherosclerosis
, vol.176
, pp. 279-287
-
-
Osaki, F.1
Ikeda, Y.2
Suehiro, T.3
-
17
-
-
58549108970
-
Pitavastatin induces PON1 expression through p44/42 mitogen-activated protein kinase signaling cascade in Huh7 cells
-
Arii K., Suehiro T., Ota K., et al. Pitavastatin induces PON1 expression through p44/42 mitogen-activated protein kinase signaling cascade in Huh7 cells. Atherosclerosis 202 (2009) 439-445
-
(2009)
Atherosclerosis
, vol.202
, pp. 439-445
-
-
Arii, K.1
Suehiro, T.2
Ota, K.3
-
18
-
-
0036933448
-
Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases: studies in atherosclerotic mice and in humans
-
Aviram M., Dornfeld L., Kaplan M., et al. Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases: studies in atherosclerotic mice and in humans. Drugs Exp Clin Res 28 (2002) 49-62
-
(2002)
Drugs Exp Clin Res
, vol.28
, pp. 49-62
-
-
Aviram, M.1
Dornfeld, L.2
Kaplan, M.3
-
19
-
-
80051855181
-
Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins
-
Aviram M., Volkova N., Coleman R., et al. Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins. J Agric Food Chem 56 (2008) 1148-1157
-
(2008)
J Agric Food Chem
, vol.56
, pp. 1148-1157
-
-
Aviram, M.1
Volkova, N.2
Coleman, R.3
-
20
-
-
27744589607
-
Anthocyanins induce cholesterol efflux from mouse peritoneal macrophages: the role of the peroxisome proliferator-activated receptor {gamma}-liver X receptor {alpha}-ABCA1 pathway
-
Xia M., Hou M., Zhu H., et al. Anthocyanins induce cholesterol efflux from mouse peritoneal macrophages: the role of the peroxisome proliferator-activated receptor {gamma}-liver X receptor {alpha}-ABCA1 pathway. J Biol Chem 280 (2005) 36792-36801
-
(2005)
J Biol Chem
, vol.280
, pp. 36792-36801
-
-
Xia, M.1
Hou, M.2
Zhu, H.3
-
21
-
-
23044467570
-
Anti-diabetic action of Punica granatum flower extract: activation of PPAR-gamma and identification of an active component
-
Huang T.H., Peng G., Kota B.P., et al. Anti-diabetic action of Punica granatum flower extract: activation of PPAR-gamma and identification of an active component. Toxicol Appl Pharmacol 207 (2005) 160-169
-
(2005)
Toxicol Appl Pharmacol
, vol.207
, pp. 160-169
-
-
Huang, T.H.1
Peng, G.2
Kota, B.P.3
-
22
-
-
0344951233
-
Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins
-
Gouédard C., Koum-Besson N., Barouki R., and Morel Y. Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins. Mol Pharmacol 63 (2003) 945-956
-
(2003)
Mol Pharmacol
, vol.63
, pp. 945-956
-
-
Gouédard, C.1
Koum-Besson, N.2
Barouki, R.3
Morel, Y.4
-
23
-
-
36048994061
-
Macrophage paraoxonase 2 (PON2) expression is up-regulated by pomegranate juice phenolic anti-oxidants via PPAR gamma and AP-1 pathway activation
-
Shiner M., Fuhrman B., and Aviram M. Macrophage paraoxonase 2 (PON2) expression is up-regulated by pomegranate juice phenolic anti-oxidants via PPAR gamma and AP-1 pathway activation. Atherosclerosis 195 (2007) 313-321
-
(2007)
Atherosclerosis
, vol.195
, pp. 313-321
-
-
Shiner, M.1
Fuhrman, B.2
Aviram, M.3
-
24
-
-
33846590071
-
Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma
-
Burgermeister E., Chuderland D., Hanoch T., et al. Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Mol Cell Biol 27 (2007) 803-817
-
(2007)
Mol Cell Biol
, vol.27
, pp. 803-817
-
-
Burgermeister, E.1
Chuderland, D.2
Hanoch, T.3
-
25
-
-
34547589477
-
Modulation of PPAR activity via phosphorylation
-
Burns K.A., and Vanden Heuvel J.P. Modulation of PPAR activity via phosphorylation. Biochim Biophys Acta 1771 (2007) 952-960
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 952-960
-
-
Burns, K.A.1
Vanden Heuvel, J.P.2
-
26
-
-
0034530972
-
Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase A activators
-
Lazennec G., Canaple L., Saugy D., and Wahli W. Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase A activators. Mol Endocrinol 14 (2000) 1962-1975
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1962-1975
-
-
Lazennec, G.1
Canaple, L.2
Saugy, D.3
Wahli, W.4
-
27
-
-
37349131707
-
Pomegranate flower: a unique traditional antidiabetic medicine with dual PPAR-alpha/-gamma activator properties
-
Li Y., Qi Y., Huang T.H., Yamahara J., and Roufogalis B.D. Pomegranate flower: a unique traditional antidiabetic medicine with dual PPAR-alpha/-gamma activator properties. Diabetes Obes Metab 10 (2008) 10-17
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 10-17
-
-
Li, Y.1
Qi, Y.2
Huang, T.H.3
Yamahara, J.4
Roufogalis, B.D.5
-
28
-
-
53549087775
-
Regulation of cellular signals from nutritional molecules: a specific role for phytochemicals, beyond antioxidant activity
-
Virgili F., and Marino M. Regulation of cellular signals from nutritional molecules: a specific role for phytochemicals, beyond antioxidant activity. Free Radic Biol Med 45 (2008) 1205-1216
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1205-1216
-
-
Virgili, F.1
Marino, M.2
|