Comparison of biological responses in rats under various cigarette smoke exposure conditions

Journal of Toxicologic Pathology

Volumn 26, Issue 2, 2013, Pages 159-174

  Tsuji, Hiroyuki ^a   Fujimoto, Hitoshi ^a   Matsuura, Daiki ^a   Nishino, Tomoki ^a   Lee, K Monica ^b   Yoshimura, Hiroyuki ^a  

^a JAPAN TOBACCO INC   (Japan)

^b JT International SA ^*  (Switzerland)

Author keywords

Bronchoalveolar lavage fluid (BALF); Cigarette smoke; Exposure marker; Inhalation; Pulmonary inflammation

Indexed keywords

CARBOXYHEMOGLOBIN; CIGARETTE SMOKE; COTININE; GAMMA GLUTAMYLTRANSFERASE; NICOTINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FISCHER 344 RAT; HEART WEIGHT; HISTOPATHOLOGY; LUNG FLUID; LUNG WEIGHT; MALE; NEUTROPHIL COUNT; NONHUMAN; NOSE; PARTICULATE MATTER; PHARYNX; RAT; SPRAGUE DAWLEY RAT; WEIGHT REDUCTION;

EID: 84880601623     PISSN: 09149198     EISSN: None     Source Type: Journal    
DOI: 10.1293/tox.26.159     Document Type: Article

References (40)

1. Taraseviciene-Stewart L, and Voelkel NF. Molecular pathogenesis of emphysema. J Clin Invest. 118: 394-402. 2008.
2. Stinn W, Arts JHE, Buettner A, Duistermaat E, Janens K, Kuper CF, and Haussmann HJ. Murine lung tumor response after exposure to cigarette mainstream smoke or its particulate and gas/vapor phase fraction. Toxicol. 275: 10-20. 2010.
3. Schroeter MR, Sawalich M, Humboldt T, Leifheit M, Meurrens K, Berges A, Xu H, Lebrun S, Wallerach T, Konstantinides S, Schleef R, and Schaefer K. Cigarette smoke exposure promotes arterial thrombosis and vessel remodeling after vascular injury in apolipoprotein E-deficient mice. J Vasc Res. 45: 480-492. 2008.
4. Chen BT, Bechtold WE, Barr EB, Chang Y-S, Mauderly JL, and Cuddihy RG. Comparison of cigarette smoke exposure atmospheres in different exposure and puffing models. Inhal Toxicol. 1: 331-347. 1989.
5. De Flora S, Balansky RM, Agostini FD, Lzzotti A, Camoirano A, Bennicelli C, Zhang Z, Wang Y, Lubet R, and You M. Molecuar alterations and lung tumors in p53 mutant mice exposed to cigarette smoke. Cancer Res. 63: 793-800. 2003.
6. Mauderly JL, Gigliotti AP, Barr EB, Bechtld WE, Blinsky SA, Hahn FF, Hobbs CA, March TH, Seilkop SK, and Finch GL. Chronic inhalation exposure to mainstream cigarette smoke increases lung and nasal tumor incidence in rats. Toxicol Sci. 81: 280-292. 2004.
7. Curtin GM, Higuchi MA, Ayres PH, Swauger JE, and Mosberg AT. Lung tumorigenicity in A/J and ras H2 transgenic mice following mainstream tobacco smoke inhalation. Toxicol Sci. 81: 26-34. 2004.
8. Baker RR, Massey EH, and Smith G. An overview of the effects of tobacco ingredients on smoke chemistry and toxicity. Food Chem Toxicol. 42: S53-S83. 2004.
9. Gebel S, Gerstmayer B, Kuhl P, Boriak J, Meurrens K, and Muller T. The kinetics of transcriptomic changes induced by cigarette smoke in rat lungs reveals a specific program of defence, inflammation, and circadian clock gene expression. Toxicol Sci. 93: 422-431. 2006.
10. Coggins CRE. An updated review of inhalation studies with cigarette smoke in laboratory animals. Int J Toxicol. 26: 331-338. 2007.
11. Hamm JT, Yee S, Rajendran N, Morrisey RL, Richter SJ, and Misra M. Histological alterations in male A/J mice following nose-only exposure to tobacco smoke. Inhal Toxicol. 19: 405-418. 2007.
12. Bolton SJ, Pinnion K, Oreffo V, Foster M, and Pinkerton KE. Characterization of the proximal airway squamous metaplasia induced by chronic tobacco smoke exposure in spontaneously hypertensive rats. Respir Res. 10: 118-133. 2009.
13. Tsuji H, Lee KM, Yoshino K, Nakamura H, Lulham G, Renne R, and Yoshimura H. Comparison of the physiological and morphological effects of cigarette smoke exposure at comparable weekly doses on Spraque-Dawley rats. Inhal Toxicol. 23: 17-32. 2011.
14. Gaworski CL, Shramke H, Diekmann J, Meisgen TJ, Tewes FJ, Veltel DJ, Vansheeuwijck PM, Rajendran N, Muzzio M, and Haussmann HJ. Effect of filtration by activated charcoal on the toxicological activity of cigarette mainstream smoke from experimental cigarette. Inhal Toxicol. 21: 688-704. 2009.
15. Carmines EL. Evaluation of potential effects of ingredients added to cigarettes. Part 1: Cigarette design, testing approach, and review of results. Food Chem Toxicol. 40: 77-91. 2002.
16. Renne RA, Yoshimura H, Yoshino K, Lulham G, Minamisawa S, Tribukait A, Dennis DD, Lee KM, and Westerberg RB. Effects of flavoring and casing ingredients on the toxicity of mainstream cigarette smoke in rats. Inhal Toxicol. 18: 685-706. 2006.
17. OECD. OECD guideline for the testing of chemicals; Subchronic inhalation Toxicity: 90-day study. Environmental Health and Safety Monograph Series on Testing and Assessment No.413. 2009. http://iccvam.niehs.nih.gov/Supp-Docs/FedDocs/OECD/OECD-TG413.pdf.
18. NTP Specifications for the Conduct of Studies to Evaluate the Reproductive and Developmental Toxicity of Chemical, Biological and Physical Agents in Laboratory Animals for the National Toxicology Program (NTP). 2011. http:// ntp.niehs.nih.gov/ntp/Test_Info/FinalNTP_ToxCarSpecs-Jan2011.pdf.
19. Shapiro SD, Goldstein NM, Houghton AM, Kobayashi DK, Kelley D, and Belaaouaj A. Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice. Am J Pathol. 163: 2329-2335. 2003.
20. Guerassimov A, Hoshino Y, Takubo Y, Turcotte A, Yamamoto M, Ghezzo H, Triantafillopoulos A, Whittaker K, Hoidal JR, and Cosio MG. The development of emphysema in cigarette smoke-exposed mice is strain dependent. Am J Respir Crit Care Med. 170: 974-980. 2004.
21. Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, and Butler K. Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic response to cigarette smoke inhalation. Am J Physiol Lung Cell Mol Physiol. 293: L1183-L1193. 2007.
22. Zheng H, Liu Y, Huang T, Fang Z, Li G, and He S. Development and characterization of a rat model of chronic obstructive pulmonary disease (COPD) induced by sidestream cigarette smoke. Toxicol Lett. 189: 225-234. 2009.
23. Gaylor DW. The use of Haber's Law in standard setting and risk assessment. Toxicology. 149: 17-19. 2000.
24. Mioduszewski R, Manthei J, Way R, Burnett D, Gaviola B, Muse W, Thomson S, Sommerville D, and Crosier R. Interaction of exposure concentration and duration in determining acute toxic effects of sarin vapor in rats. Toxicol Sci. 66: 176-184. 2002.
25. Hoyle GW, Chang W, Chen J, Schlueter CF, and Rando RJ. Deviations from Haber's Law for multiple measures of acute lung injury in chlorine-exposed mice. Toxicol Sci. 118: 696-703. 2010.
26. Coggins CR, Duchosal F, Musy C, and Ventrone R. Measurement of respiratory patterns in rodents using wholebody plethysmography and a pneumotachograph. Lab Anim. 15: 137-140. 1981.
27. Young JT. Histopathological examination of the rat nasal cavity. Fundam Appl Toxicol. 1: 309-312. 1981.
28. Renne RA, Gideon KM, Miller RA, Mellick PW, and Grumbein SL. Histologic methods and interspecies variations in the laryngeal histology of F344/N rats and B6C3F1 mice. Toxicol Pathol. 20: 44-51. 1992.
29. Terpstra PM, Teredesal A, Vansheeuwijck PM, Verbeeck J, Schepers G, Radtke F, Kuhl P, Gomm W, Anskeit E, and Patskan G. Toxicological evaluation of an electrically heated cigarette. Part 4. Subchronic inhalation toxicology. J Appl Toxicol. 23: 349-362. 2003.
30. Brass DM, Hollingsworth JW, Cinque M, Li Z, Potts E, Toloza E, Foster WM, and Schwartz DA. Chronic LPS inhalation causes emphysema-like changes in mouse lung that are associated with apoptosis. Am J Respir Cell Mol Biol. 39: 584-590. 2008.
31. Ernst A, and Zibrak JD. Carbon monoxide poisoning. N Engl J Med. 339: 1603-1608. 1998.
32. Law MR, Morris JK, Watt HC, and Wald NJ. The doseresponse relationship between cigarette consumption, biochemical markers and risk of lung cancer. Br J Cancer. 75: 1690-1693. 1997.
33. Yamazaki H, Horiuchi K, Takano R, Nagano T, Shimizu M, Kitajima M, Murayama N, and Shono F. Human blood concentrations of cotinine, a biomonitoring marker for tobacco smoke, extrapolated from nicotine metabolism in rats and humans and physiologically based pharmacokinetic modeling. Int J Environ Res Public Health. 7: 3406-3421. 2010.
34. Bouley G, Dubreuil A, Godin J, and Boudene C. Effects in the rat of a week dose of acrolein inhaled continuously. Eur J Toxicol Environ Hyg. 8: 291-297. 1975.
35. Chowdhury P. Endocrine and metabolic regulation of body mass by nicotine: role of growth hormone. Ann Clin Lab Sci. 20: 415-419. 1990.
36. Russell RE, Thorley A, Culpitt SV, Dodd S, Donnelly LE, Demattos C, Fitzgerald M, and Barnes PJ. Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, syteine, and serine proteases. Am J Physiol Lung Cell Mol Physiol. 283: L867-L873. 2002.
37. Churg A, Wang RD, Tai H, Wang X, Xie C, and Wright JL. Tumor necrosis factor-α drives 70% of cigarette smokeinduced emphysema in the mouse. Am J Respir Crit Care Med. 170: 492-498. 2004.
38. Moriyama C, Betsuyaku T, Ito Y, Hamamura I, Hata J, Takahashi H, Nasuhara Y, and Nishimura M. Aging enhances susceptibility to cigarette smoke-induced inflammation through bronchiolar chemokines. Am J Respir Cell Mol Biol. 42: 304-311. 2010.
39. Penney D, Benjamin M, and Dunham E. Effect of carbon monoxide on cardiac weight as compared with altitude effects. J Appl Physiol. 37: 80-84. 1974.
40. March TH, Barr EB, Finch GL, Hahn FF, Hobbs CH, Menache MG, and Nikula KJ. Cigarette smoke exposure produces more evidence of emphysema in B6C3F1 mice than F344 rats. Toxicol Sci. 51: 289-299. 1999.