Age-related change of neurochemical abnormality in attention-deficit hyperactivity disorder: A meta-analysis

Neuroscience and Biobehavioral Reviews

Volumn 37, Issue 8, 2013, Pages 1692-1701

  Aoki, Yuta ^a,b   Inokuchi, Ryota ^b,c   Suwa, Hiroshi ^a   Aoki, Ai ^a  

^a Department of Dentistry Oral surgery   (Japan)

^b UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

ADD; ADHD; Attention deficit disorder; Magnetic resonance spectroscopy; Methylphenidate; MRS

Indexed keywords

N ACETYLASPARTIC ACID;

ADULT; AGING; ATTENTION DEFICIT DISORDER; CEREBELLUM; CHILD; CORPUS STRIATUM; CORRELATION ANALYSIS; HUMAN; META ANALYSIS; METABOLITE; NEUROCHEMISTRY; PREFRONTAL CORTEX; PREVALENCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REVIEW; SENSITIVITY ANALYSIS; SYMPTOM; SYSTEMATIC REVIEW;

ADD; ADHD; ATTENTION DEFICIT DISORDER; MAGNETIC RESONANCE SPECTROSCOPY; METHYLPHENIDATE; MRS;

AGE FACTORS; AGING; ASPARTIC ACID; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PREFRONTAL CORTEX;

EID: 84880589215     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2013.04.019     Document Type: Review

References (52)

1. Aoki Y., Abe O., Yahata N., Kuwabara H., Natsubori T., Iwashiro N., Takano Y., Inoue H., Kawakubo Y., Gonoi W., Sasaki H., Murakami M., Katsura M., Nippashi Y., Takao H., Kunimatsu A., Matsuzaki H., Tsuchiya K.J., Kato N., Kasai K., Yamasue H. Absence of age-related prefrontal NAA change in adults with autism spectrum disorders. Transl. Psychiatry 2012, 2:e178.
2. Aoki Y., Aoki A., Suwa H. Reduction of N-acetylaspartate in the medial prefrontal cortex correlated with symptom severity in obsessive-compulsive disorder: meta-analyses of 1H-MRS studies. Transl. Psychiatry 2012, 2:e153.
3. Aoki Y., Inokuchi R., Gunshin M., Yahagi N., Suwa H. Diffusion tensor imaging studies of mild traumatic brain injury: a meta-analysis. J. Neurol. Neurosurg. Psychiatry 2012, 83:870-876. 10.1016/j.jcv.2012.12.013.
4. Aoki Y., Kasai K., Yamasue H. Age-related change in brain metabolite abnormalities in autism: a meta-analysis of proton magnetic resonance spectroscopy studies. Transl. Psychiatry 2012, 2:e69.
5. Arcos-Burgos M., Londoño A.C., Pineda D.A., Lopera F., Palacio J.D., Arbelaez A., Acosta M.T., Vélez J.I., Castellanos F.X., Muenke M. Analysis of brain metabolism by proton magnetic resonance spectroscopy ((1)H-MRS) in attention-deficit/hyperactivity disorder suggests a generalized differential ontogenic pattern from controls. Atten. Defic. Hyperact. Disord. 2012, 4:205-212. 10.1007/s12402-012-0088-0.
6. Baslow M.H. A novel key-lock mechanism for inactivating amino acid neurotransmitters during transit across extracellular space. Amino Acids 2010, 38:51-55.
7. Baslow M.H. The vertebrate brain, evidence of its modular organization and operating system: insights into the brain's basic units of structure, function, and operation and how they influence neuronal signaling and behavior. Front. Behav. Neurosci. 2011, 5:5.
8. Biederman J., Faraone S.V., Petty C., Martelon M., Woodworth K.Y., Wozniak J. Further evidence that pediatric-onset bipolar disorder comorbid with ADHD represents a distinct subtype: results from a large controlled family study. J. Psychiatry Res. 2013, 47:15-22. 10.1016/j.jpsychires.2012.08.002.
9. Borenstein M., Hedges L.V., Higgins J.P.T., Rothstein H.R. Introduction to meta-analysis. 2011, John Wiley and Sons, Chichester, West Sussex, UK.
10. Brennan B.P., Rauch S.L., Jensen J.E., Pope H.G. A critical review of magnetic resonance spectroscopy studies of obsessive-compulsive disorder. Biol. Psychiatry 2013, 73:24-41.
11. Bush G. Attention-deficit/hyperactivity disorder and attention networks. Neuropsychopharmacology 2010, 35:278-300.
12. Bustillo J.R., Rowland L.M., Mullins P., Jung R., Chen H., Qualls C., Hammond R., Brooks W.M., Lauriello J. 1H-MRS at 4 tesla in minimally treated early schizophrenia. Mol. Psychiatry 2010, 15:629-636.
13. Carrey N., Macmaster F.P., Fogel J., Sparkes S., Waschbusch D., Sullivan S., Schmidt M. Metabolite changes resulting from treatment in children with ADHD: a 1H-MRS study. Clin. Neuropharmacol. 2003, 26:218-221.
14. Carrey N., Macmaster F.P., Sparkes S.J., Khan S.C., Kusumakar V. Glutamatergic changes with treatment in attention deficit hyperactivity disorder: a preliminary case series. J. Child Adolesc. Psychopharmacol. 2002, 12:331-336.
15. Carrey N.J., Macmaster F.P., Gaudet L., Schmidt M.H. Striatal creatine and glutamate/glutamine in attention-deficit/hyperactivity disorder. J. Child Adolesc. Psychopharmacol. 2007, 17:11-17.
16. Colla M., Ende G., Alm B., Deuschle M., Heuser I., Kronenberg G. Cognitive MR spectroscopy of anterior cingulate cortex in ADHD: elevated choline signal correlates with slowed hit reaction times. J. Psychiatry Res. 2008, 42:587-595.
17. Cortese S., Kelly C., Chabernaud C., Proal E., Di Martino A., Milham M.P., Castellanos F.X. Toward systems neuroscience of ADHD: a meta-analysis of 55 fMRI studies. Am. J. Psychiatry 2012, 169:1038-1055. 10.1176/appi.ajp.2012.11101521.
18. Courvoisie H., Hooper S.R., Fine C., Kwock L., Castillo M. Neurometabolic functioning and neuropsychological correlates in children with ADHD-H: preliminary findings. J. Neuropsychiatry Clin. Neurosci. 2004, 16:63-69.
19. Dramsdahl M., Ersland L., Plessen K.J., Haavik J., Hugdahl K., Specht K. Adults with attention-deficit/hyperactivity disorder - a brain magnetic resonance spectroscopy study. Front. Psychiatry 2011, 2:65.
20. Edden R.A.E., Crocetti D., Zhu H., Gilbert D.L., Mostofsky S.H. Reduced GABA concentration in attention-deficit/hyperactivity disorder. Arch. Gen. Psychiatry 2012, 69:750-753.
21. Faraone S.V., Biederman J., Mick E. The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies. Psychol. Med. 2006, 36:159-165.
22. Fayed N., Modrego P.J. Comparative study of cerebral white matter in autism and attention-deficit/hyperactivity disorder by means of magnetic resonance spectroscopy. Acad. Radiol. 2005, 12:566-569.
23. Fayed N., Modrego P.J., Castillo J., Dávila J. Evidence of brain dysfunction in attention deficit-hyperactivity disorder: a controlled study with proton magnetic resonance spectroscopy. Acad. Radiol. 2007, 14:1029-1035.
24. Ferreira P.E.M.S., Palmini A., Bau C.H.D., Grevet E.H., Hoefel J.R., Rohde L.A., Anés M., Ferreira E.E., Belmonte-de-Abreu P. Differentiating attention-deficit/hyperactivity disorder inattentive and combined types: a (1)H-magnetic resonance spectroscopy study of fronto-striato-thalamic regions. J. Neural. Transm. 2009, 116:623-629.
25. Gomez R., Behar K.L., Watzl J., Weinzimer S.A., Gulanski B., Sanacora G., Koretski J., Guidone E., Jiang L., Petrakis I.L., Pittman B., Krystal J.H., Mason G.F. Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla. Biol. Psychiatry 2012, 71:239-246.
26. Hammerness P., Biederman J., Petty C., Henin A., Moore C.M. Brain biochemical effects of methylphenidate treatment using proton magnetic spectroscopy in youth with attention-deficit hyperactivity disorder: a controlled pilot study. CNS Neurosci. Ther. 2010, 18:34-40.
27. Hart H., Radua J., Mataix-Cols D., Rubia K. Meta-analysis of fMRI studies of timing in attention-deficit hyperactivity disorder (ADHD). Neurosci. Biobehav. Rev. 2012, 36:2248-2256.
28. Hesslinger B., Thiel T., Tebartz van Elst L., Hennig J., Ebert D. Attention-deficit disorder in adults with or without hyperactivity: where is the difference?. A study in humans using short echo (1)H-magnetic resonance spectroscopy. Neurosci. Lett. 2001, 304:117-119.
29. Higgins J., Green S. Cochrane Handbook for Systematic Reviews of Interventions 2008.
30. Jin Z., Zang Y.F., Zeng Y.W., Zhang L., Wang Y.F. Striatal neuronal loss or dysfunction and choline rise in children with attention-deficit hyperactivity disorder: a 1H-magnetic resonance spectroscopy study. Neurosci. Lett. 2001, 315:45-48.
31. Kato T., Inubushi T., Kato N. Magnetic resonance spectroscopy in affective disorders. J. Neuropsychiatry Clin. Neurosci. 1998, 10:133-147.
32. Kronenberg G., Ende G., Alm B., Deuschle M., Heuser I., Colla M. Increased NAA and reduced choline levels in the anterior cingulum following chronic methylphenidate. A spectroscopic test-retest study in adult ADHD. Eur. Arch. Psychiatry Clin. Neurosci. 2008, 258:446-450.
33. Macmaster F.P., Carrey N., Sparkes S., Kusumakar V. Proton spectroscopy in medication-free pediatric attention-deficit/hyperactivity disorder. Biol. Psychiatry 2003, 53:184-187.
34. Magistretti P.J., Pellerin L. Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging. Philos. Trans. R. Soc. Lond. B Biol. Sci. 1999, 354:1155-1163.
35. Manji H., Kato T., Di Prospero N.A., Ness S., Beal M.F., Krams M., Chen G. Impaired mitochondrial function in psychiatric disorders. Nat. Rev. Neurosci. 2012, 13:293-307.
36. Moore C.M., Biederman J., Wozniak J., Mick E., Aleardi M., Wardrop M., Dougherty M., Harpold T., Hammerness P., Randall E., Renshaw P.F. Differences in brain chemistry in children and adolescents with attention deficit hyperactivity disorder with and without comorbid bipolar disorder: a proton magnetic resonance spectroscopy study. Am. J. Psychiatry 2006, 163:316-318.
37. Nakao T., Radua J., Rubia K., Mataix-Cols D. Gray matter volume abnormalities in ADHD: voxel-based meta-analysis exploring the effects of age and stimulant medication. Am. J. Psychiatry 2011, 168:1154-1163.
38. Perlov E., Philipsen A., Hesslinger B., Buechert M., Ahrendts J., Feige B., Bubl E., Hennig J., Ebert D., Tebartz van Elst L. Reduced cingulate glutamate/glutamine-to-creatine ratios in adult patients with attention deficit/hyperactivity disorder - a magnet resonance spectroscopy study. J. Psychiatry Res. 2007, 41:934-941.
39. Perlov E., Philipsen A., Matthies S., Drieling T., Maier S., Bubl E., Hesslinger B., Buechert M., Henning J., Ebert D., Tebartz Van Elst L. Spectroscopic findings in attention-deficit/hyperactivity disorder: review and meta-analysis. World J. Biol. Psychiatry 2009, 10:355-365.
40. Perlov E., van Elst L.T., Buechert M., Maier S., Matthies S., Ebert D., Hesslinger B., Philipsen A. H1-MR-spectroscopy of cerebellum in adult attention deficit/hyperactivity disorder. J. Psychiatry Res. 2010, 44:938-943.
41. Peterson B.S., Potenza M.N., Wang Z., Zhu H., Martin A., Marsh R., Plessen K.J., Yu S. An fMRI study of the effects of psychostimulants on default-mode processing during Stroop task performance in youths with ADHD. Am. J. Psychiatry 2009, 166:1286-1294.
42. Rothman D.L., Behar K.L., Hyder F., Shulman R.G. In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain function. Annu. Rev. Physiol. 2003, 65:401-427.
43. Rowland L.M., Bustillo J.R., Mullins P.G., Jung R.E., Lenroot R., Landgraf E., Barrow R., Yeo R., Lauriello J., Brooks W.M. Effects of ketamine on anterior cingulate glutamate metabolism in healthy humans: a 4-T proton MRS study. Am. J. Psychiatry 2005, 162:394-396.
44. Rüsch N., Boeker M., Büchert M., Glauche V., Bohrmann C., Ebert D., Lieb K., Hennig J., Tebartz Van Elst L. Neurochemical alterations in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder. World J. Biol. Psychiatry 2010, 11:372-381.
45. Soliva J.C., Moreno A., Fauquet J., Bielsa A., Carmona S., Gispert J.D., Rovira M., Bulbena A., Vilarroya O. Cerebellar neurometabolite abnormalities in pediatric attention/deficit hyperactivity disorder: a proton MR spectroscopic study. Neurosci. Lett. 2010, 470:60-64.
46. Stroup D.F., Berlin J.A., Morton S.C., Olkin I., Williamson G.D., Rennie D., Moher D., Becker B.J., Sipe T.A., Thacker S.B. Meta-analysis of observational studies in epidemiology: a proposal for reporting, Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000, 283:2008-2012.
47. Sun L., Jin Z., Zang Y.-F., Zeng Y.-W., Liu G., Li Y., Seidman L.J., Faraone S.V., Wang Y.-F. Differences between attention-deficit disorder with and without hyperactivity: a 1H-magnetic resonance spectroscopy study. Brain Dev. 2005, 27:340-344.
48. Valera E.M., Faraone S.V., Murray K.E., Seidman L.J. Meta-analysis of structural imaging findings in attention-deficit/hyperactivity disorder. Biol. Psychiatry 2007, 61:1361-1369.
49. Wiguna T., Guerrero A.P.S., Wibisono S., Sastroasmoro S. Effect of 12-week administration of 20-mg long-acting methylphenidate on Glu/Cr, NAA/Cr, Cho/Cr, and mI/Cr ratios in the prefrontal cortices of school-age children in Indonesia. Clin. Neuropharmacol. 2012, 35:81-85.
50. Yang P., Wu M.-T., Dung S.-S., Ko C.-W. Short-TE proton magnetic resonance spectroscopy investigation in adolescents with attention-deficit hyperactivity disorder. Psychiatry Res. 2010, 181:199-203.
51. Yang S., Hu J., Kou Z., Yang Y. Spectral simplification for resolved glutamate and glutamine measurement using a standard STEAM sequence with optimized timing parameters at 3, 4, 4.7, 7, and 9.4T. Magn. Reson. Med. 2008, 59:236-244.
52. Yeo R.A., Hill D.E., Campbell R.A., Vigil J., Petropoulos H., Hart B., Zamora L., Brooks W.M. Proton magnetic resonance spectroscopy investigation of the right frontal lobe in children with attention-deficit/hyperactivity disorder. J. Am. Acad. Child Adolesc. Psychiatry 2003, 42:303-310.