Effect of 12-week administration of 20-mg long-acting methylphenidate on Glu/Cr, NAA/Cr, Cho/Cr, and mI/Cr ratios in the prefrontal cortices of school-age children in Indonesia: A study using 1H Magnetic Resonance Spectroscopy (MRS)

Clinical Neuropharmacology

Volumn 35, Issue 2, 2012, Pages 81-85

  Wiguna, Tjhin ^a   Guerrero, Anthony P S ^b   Wibisono, Sasanto ^a   Sastroasmoro, Sudigdo ^a  

^a UNIVERSITY OF INDONESIA   (Indonesia)

^b UNIVERSITY OF HAWAII   (United States)

Author keywords

ADHD; long acting methylphenidate; MRS; prefrontal cortex

Indexed keywords

CHOLINE; CREATININE; GLUTAMIC ACID; INOSITOL; METHYLPHENIDATE; N ACETYLASPARTIC ACID;

ARTICLE; ATTENTION DEFICIT DISORDER; CHILD; CLINICAL ARTICLE; DRUG EFFECT; DRUG MECHANISM; FEMALE; HUMAN; INDONESIA; MALE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCHOOL CHILD;

ADULT; ASPARTIC ACID; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CHILD; CHOLINE; CREATINE; FEMALE; GLUTAMIC ACID; HUMANS; INDONESIA; INOSITOL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METHYLPHENIDATE; MIDDLE AGED; PREFRONTAL CORTEX; PROSPECTIVE STUDIES; PROTONS; TIME FACTORS;

EID: 84858765447     PISSN: 03625664     EISSN: 1537162X     Source Type: Journal    
DOI: 10.1097/WNF.0b013e3182452572     Document Type: Article

References (25)

1. Landgren M, Petterson R, Kjellman B, et al. ADHD, DAMP and other neurodevelopmental/psychiatric disorders in 6-year old children: epidemiology and co-morbidity. Dev Med and Child Neurology 1996;38:891-906. (Pubitemid 26340848)
2. Furman RA. Attention deficit/hyperactivity disorder: an alternative viewpoint. J Int Child Adolesc Psychiatry 2002;2:125-144.
3. Rohde LA, Szobot C, Polanczyk G, et al. Attention-deficit/hyperactivity disorder in a diverse culture: do research and clinical findings support the notion of a cultural construct for the disorder? Biol Psychiatry 2005;57(11):1436-1441 (Pubitemid 40798565)
4. Tanjung IS, Wiguna T, Humris EP. The Prevalence of ADHD Among Primary School Children Grades 1-3 in Central Jakarta, Indonesia. Department of Psychiatry, University of Indonesia; 2002. Thesis.
5. Saputro D. Childhood Hyperkinetic Disorder in Jakarta-Indonesia, New Screening Instrument Development, Prevalence Study, Pathophysiological Research, and Therapy Approach. Medical Faculty, University of Gajah Mada-Central Java; 2004. Dissertation.
6. Vaidya CJ, Gabrieli JDE. Searching for a neurobiological signature of attention deficit hyperactivity disorder. Mol Psychiatry 1999;4:206-208. (Pubitemid 29292164)
7. Faraone SV, Doyle AE, Mick E, et al. Meta-Analysis of the association between the 7-repeat allele of the dopamine D4 receptor gene and attention deficit hyperactivity disorder. Am J Psychiatry 2001;158:1052-1057. (Pubitemid 32623108)
8. Middleton FA, Strick PL. Cerebellar projections to the prefrontal cortex of the primate. Neurosci 2001;21:700-712. (Pubitemid 32107458)
9. Barkley RA. Attention-deficit/hyperactive disorder. In: Mash EJ, Berkley RA, eds. Child Psychopathology. 2nd ed. New York, NY: The Guilford Press; 2004:75-143.
10. Hyman SE. Methylphenidate-induced plasticity: what should we be looking for? Biol Psychiatry 2003;54:1310-1311 (Pubitemid 37522153)
11. Volkow ND, Wang GJ, Fowler JS, et al. Imaging the effect of methylphenidate on brain dopamine: new model on its therapeutic actions for attention-deficit/hyperactivity disorder. Biol Psychiatry 2005;57:1410-1415. (Pubitemid 40798562)
12. McCracken JT. Attention-deficit disorder. Sadock BJ, Sadock VA, eds. Comprehensive Textbook of Psychiatry. 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2000:2679-2692.
13. Brandon L, Domingues RC. MRS of the Brain. Philadelphia, NY: Lippincott William & Wilkins; 2004:7-29.
14. Jin Z, Zang YF, Zeng YW, et al. Striatal neuronal loss or dysfunction and choline rise in children with attention-deficit hyperactivity disorder: a 1H-magnetic resonance spectroscopy study. Neurosci Lett 2001;315(1-2):45-48. (Pubitemid 33049995)
15. Danielsen ER, Ross B. Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases. New York-Basel, Switzerland: Marcel Dekker Inc; 1999:8-102.
16. MacMaster FP, Carrey N, Sparkes S, et al. Proton spectroscopy in medication-free pediatric attention-deficit/hyperactivity disorder. Biol Psychiatry 2003;53:184-187. (Pubitemid 36126483)
17. Courvoisie H, Hooper SR, Fine C, et al. Neurometabolic functioning and neuropsychological correlates in children with ADHD-H: preliminary findings. J Neuropsychiatry Clin Neurosci 2004;16:63-69. (Pubitemid 38233365)
18. Carrey N, MacMaster FP, Sparkes SJ, et al. Glutamatergic changes with treatment in attention deficit hyperactivity disorder: a preliminary case series. J Child Adolesc Psychopharmacol 2002;12(4):331-336. (Pubitemid 36169285)
19. Carrey N, MacMaster FP, Fogel J, et al. Metabolite changes resulting from treatment in children with ADHD: a 1H-MRS study. Clin Neuropharmacol 2003;26(4):218-221. (Pubitemid 36951069)
20. Carrey NJ, MacMaster FP, Gaudet L, et al. Striatal creatine and glutamate/glutamine in attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol 2007;17(1):11-17. (Pubitemid 46452078)
21. Kronenberg G, Ende G, Alm B, et al. Increased NAA and reduced choline levels in the anterior cingulum following chronic methylphenidate. A spectroscopic test-retest study in adult ADHD. Eur Arch Psychiatry Clin Neurosci 2008;258(7):446-450.
22. Machin D, Campbell MJ, Fayers PM, et al. Sample Size Tables for Clinical Studies. London, UK: Blackwell Science Ltd; 1997:37-68.
23. Wilens T, McBurnett K, Stein M, et al. ADHD treatment with once-daily OROS methylphenidate: final results from a long-term open-label study. J Am Acad Child Adolesc Psychiatry 2005;44:1015-1023. (Pubitemid 41377557)
24. Volkow ND, Wang GI, Fowler JS, et al. 'Nonhedonic' food motivation in human involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse 2002;44:175-180. (Pubitemid 34303915)
25. Steele M, Weiss M, Swanson J, et al. A randomized, controlled effectiveness trial of OROS-methylphenidate compared to usual care with immediate-release methylphenidate in ADHD. Can J Clin Pharmacol 2006;13:51-62.