The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs)

Age

Volumn 35, Issue 2, 2013, Pages 315-330

  Kucia, Magda ^a,b   Masternak, Michal ^c,e,f   Liu, Riu ^a   Shin, Dong Myung ^a   Ratajczak, Janina ^a,b   Mierzejewska, Katarzyna ^a   Spong, Adam ^e,f   Kopchick, John J ^d   Bartke, Andrzej ^e,f   Ratajczak, Mariusz Z ^a,b  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b POMERANIAN MEDICAL UNIVERSITY   (Poland)

^c UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^d OHIO UNIVERSITY   (United States)

^e SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f INSTITUTE OF HUMAN GENETICS   (Poland)

Author keywords

Aging; GH; IGF 1; VSELs

Indexed keywords

DNA; GROWTH HORMONE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; SOMATOMEDIN C;

ADULT ANIMAL; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL COUNT; CELL PROTECTION; CONTROLLED STUDY; DEPLETION; DNA METHYLATION; FEMALE; GENE; GENOME IMPRINTING; GF 2 H19 GENE; IG2R GENE; MALE; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PREMATURE AGING; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RASGRF1 GENE; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL NICHE; TRANSGENIC MOUSE; VERY SMALL EMBRYONIC LIKE STEM CELL; WILD TYPE;

AGING; ANALYSIS OF VARIANCE; ANIMALS; BONE MARROW; CELL SIZE; GENOMIC IMPRINTING; GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; MICE; MICE, TRANSGENIC; PLURIPOTENT STEM CELLS; SIGNAL TRANSDUCTION;

EID: 84880573002     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-011-9364-8     Document Type: Article

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