Multimechanistic Antifibrotic Effect of Biochanin A in Rats: Implications of Proinflammatory and Profibrogenic Mediators

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Breikaa, Randa M ^a   Algandaby, Mardi M ^b   El Demerdash, Ebtehal ^a   Abdel Naim, Ashraf B ^a  

^a Ain Shams University   (Egypt)

^b KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ALPHA SMOOTH MUSCLE ACTIN; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BIOCHANIN A; CARBON TETRACHLORIDE; CATALASE; CHOLESTEROL; CYCLOOXYGENASE 2; CYTOCHROME P450 1A1; CYTOCHROME P450 2E1; GELATINASE B; GLUTATHIONE; HYDROXYPROLINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOCYANINE GREEN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPID PEROXIDE; NITRIC OXIDE; PROTEIN; SOMATOMEDIN C; SULFOTRANSFERASE 1A1; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFIBROTIC EFFECT; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG CLEARANCE; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MECHANISM; ENZYME ACTIVITY; HISTOPATHOLOGY; INFLAMMATION; LIVER FIBROSIS; LIVER INJURY; LIVER METABOLISM; LIVER PROTECTION; LIVER WEIGHT; MALE; METABOLIC PARAMETERS; NONHUMAN; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TOTAL ANTIOXIDANT CAPACITY; TOXIC HEPATITIS; TRIACYLGLYCEROL BLOOD LEVEL;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CARBON TETRACHLORIDE; CYTOCHROME P-450 ENZYME SYSTEM; DRUG-INDUCED LIVER INJURY; FIBROSIS; GENISTEIN; LIVER; MALE; RATS; RATS, WISTAR;

EID: 84880491125     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069276     Document Type: Article

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