Endothelin receptor antagonists attenuate the inflammatory response of human pulmonary vascular smooth muscle cells to bacterial endotoxin

Journal of Pharmacology and Experimental Therapeutics

Volumn 346, Issue 2, 2013, Pages 290-299

  Knobloch, Jürgen ^a   Feldmann, Maria ^a   Wahl, Chiara ^a   Jungck, David ^a   Behr, Jürgen ^b   Stoelben, Erich ^c   Koch, Andrea ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c Lungenklinik Merheim   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMBRISENTAN; BOSENTAN; CD14 ANTIGEN; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; INTERLEUKIN 8; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; TOLL LIKE RECEPTOR 4;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD14; CELLS, CULTURED; CYTOKINES; HUMANS; INFLAMMATION; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OLIGOPEPTIDES; PHENYLPROPIONATES; PIPERIDINES; PULMONARY ARTERY; PYRIDAZINES; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; RNA, MESSENGER; SALMONELLA; SULFONAMIDES;

EID: 84880433144     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.202358     Document Type: Article

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