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Volumn 93, Issue , 2013, Pages 1-49

Estrogen-Mediated Mechanisms to Control the Growth and Apoptosis of Breast Cancer Cells. A Translational Research Success Story.

Author keywords

Aromatase inhibitors; Chemoprevention; Estrogen induced apoptosis; Raloxifene; Selective estrogen receptor modulators; Tamoxifen

Indexed keywords


EID: 84880311905     PISSN: 00836729     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-416673-8.00007-1     Document Type: Chapter
Times cited : (14)

References (230)
  • 1
    • 0000673542 scopus 로고
    • An ovarian hormone: Preliminary reports on its localization, extraction and partial purification and action in test animals
    • Allen E., Doisey E.A. An ovarian hormone: Preliminary reports on its localization, extraction and partial purification and action in test animals. Journal of the American Medical Association 1923, 81(10):819-821.
    • (1923) Journal of the American Medical Association , vol.81 , Issue.10 , pp. 819-821
    • Allen, E.1    Doisey, E.A.2
  • 2
    • 84860474009 scopus 로고    scopus 로고
    • Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: Extended follow-up of the Women's Health Initiative randomised placebo-controlled trial
    • Anderson G.L., Chlebowski R.T., Aragaki A.K., Kuller L.H., Manson J.E., Gass M., et al. Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: Extended follow-up of the Women's Health Initiative randomised placebo-controlled trial. The Lancet Oncology 2012, 13(5):476-486.
    • (2012) The Lancet Oncology , vol.13 , Issue.5 , pp. 476-486
    • Anderson, G.L.1    Chlebowski, R.T.2    Aragaki, A.K.3    Kuller, L.H.4    Manson, J.E.5    Gass, M.6
  • 3
    • 1842867053 scopus 로고    scopus 로고
    • Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: The Women's Health Initiative randomized controlled trial
    • Anderson G.L., Limacher M., Assaf A.R., Bassford T., Beresford S.A., Black H., et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: The Women's Health Initiative randomized controlled trial. Journal of the American Medical Association 2004, 291(14):1701-1712.
    • (2004) Journal of the American Medical Association , vol.291 , Issue.14 , pp. 1701-1712
    • Anderson, G.L.1    Limacher, M.2    Assaf, A.R.3    Bassford, T.4    Beresford, S.A.5    Black, H.6
  • 5
    • 84864558874 scopus 로고    scopus 로고
    • Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: A GINECO study
    • Bachelot T., Bourgier C., Cropet C., Ray-Coquard I., Ferrero J.M., Freyer G., et al. Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: A GINECO study. Journal of Clinical Oncology 2012, 30(22):2718-2724.
    • (2012) Journal of Clinical Oncology , vol.30 , Issue.22 , pp. 2718-2724
    • Bachelot, T.1    Bourgier, C.2    Cropet, C.3    Ray-Coquard, I.4    Ferrero, J.M.5    Freyer, G.6
  • 6
    • 0020693083 scopus 로고
    • Identification of a new metabolite of tamoxifen in patient serum during breast cancer therapy
    • Bain R.R., Jordan V.C. Identification of a new metabolite of tamoxifen in patient serum during breast cancer therapy. Biochemical Pharmacology 1983, 32(2):373-375.
    • (1983) Biochemical Pharmacology , vol.32 , Issue.2 , pp. 373-375
    • Bain, R.R.1    Jordan, V.C.2
  • 7
    • 77954148994 scopus 로고    scopus 로고
    • Raloxifene-stimulated experimental breast cancer with the paradoxical actions of estrogen to promote or prevent tumor growth: A unifying concept in anti-hormone resistance
    • Balaburski G.M., Dardes R.C., Johnson M., Haddad B., Zhu F., Ross E.A., et al. Raloxifene-stimulated experimental breast cancer with the paradoxical actions of estrogen to promote or prevent tumor growth: A unifying concept in anti-hormone resistance. International Journal of Oncology 2010, 37(2):387-398.
    • (2010) International Journal of Oncology , vol.37 , Issue.2 , pp. 387-398
    • Balaburski, G.M.1    Dardes, R.C.2    Johnson, M.3    Haddad, B.4    Zhu, F.5    Ross, E.A.6
  • 9
    • 66849136781 scopus 로고    scopus 로고
    • Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer
    • Baselga J., Semiglazov V., van Dam P., Manikhas A., Bellet M., Mayordomo J., et al. Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. Journal of Clinical Oncology 2009, 27(16):2630-2637.
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.16 , pp. 2630-2637
    • Baselga, J.1    Semiglazov, V.2    van Dam, P.3    Manikhas, A.4    Bellet, M.5    Mayordomo, J.6
  • 10
    • 0037157603 scopus 로고    scopus 로고
    • Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial
    • Baum M., Budzar A.U., Cuzick J., Forbes J., Houghton J.H., Klijn J.G., et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial. The Lancet 2002, 359(9324):2131-2139.
    • (2002) The Lancet , vol.359 , Issue.9324 , pp. 2131-2139
    • Baum, M.1    Budzar, A.U.2    Cuzick, J.3    Forbes, J.4    Houghton, J.H.5    Klijn, J.G.6
  • 13
    • 50549123220 scopus 로고
    • On the treatment of inoperable cases of carcinoma of the mamma: Suggestions for a new method of treatment, with illustrative cases
    • Beatson G.T. On the treatment of inoperable cases of carcinoma of the mamma: Suggestions for a new method of treatment, with illustrative cases. The Lancet 1896, 148:104-107.
    • (1896) The Lancet , vol.148 , pp. 104-107
    • Beatson, G.T.1
  • 14
    • 84863892191 scopus 로고    scopus 로고
    • FACT: An open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer
    • Bergh J., Jonsson P.E., Lidbrink E.K., Trudeau M., Eiermann W., Brattstrom D., et al. FACT: An open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer. Journal of Clinical Oncology 2012, 30(16):1919-1925.
    • (2012) Journal of Clinical Oncology , vol.30 , Issue.16 , pp. 1919-1925
    • Bergh, J.1    Jonsson, P.E.2    Lidbrink, E.K.3    Trudeau, M.4    Eiermann, W.5    Brattstrom, D.6
  • 16
    • 0023732493 scopus 로고
    • Lipophilic impurities, not phenolsulfonaphthalein, account for the estrogenic activity in commercial preparations of phenol red
    • Bindal R.D., Carlson K.E., Katzenellenbogen B.S., Katzenellenbogen J.A. Lipophilic impurities, not phenolsulfonaphthalein, account for the estrogenic activity in commercial preparations of phenol red. Journal of Steroid Biochemistry 1988, 31(3):287-293.
    • (1988) Journal of Steroid Biochemistry , vol.31 , Issue.3 , pp. 287-293
    • Bindal, R.D.1    Carlson, K.E.2    Katzenellenbogen, B.S.3    Katzenellenbogen, J.A.4
  • 17
    • 0023752961 scopus 로고
    • Bis(4-hydroxyphenyl)[2-(phenoxysulfonyl)phenyl]methane: Isolation and structure elucidation of a novel estrogen from commercial preparations of phenol red (phenolsulfonphthalein)
    • Bindal R.D., Katzenellenbogen J.A. Bis(4-hydroxyphenyl)[2-(phenoxysulfonyl)phenyl]methane: Isolation and structure elucidation of a novel estrogen from commercial preparations of phenol red (phenolsulfonphthalein). Journal of Medicinal Chemistry 1988, 31(10):1978-1983.
    • (1988) Journal of Medicinal Chemistry , vol.31 , Issue.10 , pp. 1978-1983
    • Bindal, R.D.1    Katzenellenbogen, J.A.2
  • 18
    • 0020694796 scopus 로고
    • Antagonism of estrogen action with a new benzothiophene derived antiestrogen
    • Black L.J., Jones C.D., Falcone J.F. Antagonism of estrogen action with a new benzothiophene derived antiestrogen. Life Sciences 1983, 32(9):1031-1036.
    • (1983) Life Sciences , vol.32 , Issue.9 , pp. 1031-1036
    • Black, L.J.1    Jones, C.D.2    Falcone, J.F.3
  • 19
    • 24644519961 scopus 로고    scopus 로고
    • Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: Preliminary results of the Italian Tamoxifen Anastrozole Trial
    • Boccardo F., Rubagotti A., Puntoni M., Guglielmini P., Amoroso D., Fini A., et al. Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: Preliminary results of the Italian Tamoxifen Anastrozole Trial. Journal of Clinical Oncology 2005, 23(22):5138-5147.
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.22 , pp. 5138-5147
    • Boccardo, F.1    Rubagotti, A.2    Puntoni, M.3    Guglielmini, P.4    Amoroso, D.5    Fini, A.6
  • 21
    • 0001733527 scopus 로고
    • On oophorectomy in cancer of the breast
    • Boyd S. On oophorectomy in cancer of the breast. British Medical Journal 1900, 2:1161-1167.
    • (1900) British Medical Journal , vol.2 , pp. 1161-1167
    • Boyd, S.1
  • 23
    • 84880291676 scopus 로고    scopus 로고
    • Breast Cancer Facts and Figures (2011-2012). Atlanta, American Cancer Society: American Cancer Society, Inc.
    • Breast Cancer Facts and Figures (2011-2012). Atlanta, American Cancer Society: American Cancer Society, Inc.
  • 24
    • 84880270228 scopus 로고    scopus 로고
    • Breast Cancer Survival Rates by Stage. American Cancer Society.
    • Breast Cancer Survival Rates by Stage (2011). American Cancer Society.
    • (2011)
  • 25
    • 0018914490 scopus 로고
    • Inhibition of peripheral aromatization by aromatase inhibitors, 4-hydroxy- and 4-acetoxy-androstene-3,17-dione
    • Brodie A.M., Longcope C. Inhibition of peripheral aromatization by aromatase inhibitors, 4-hydroxy- and 4-acetoxy-androstene-3,17-dione. Endocrinology 1980, 106(1):19-21.
    • (1980) Endocrinology , vol.106 , Issue.1 , pp. 19-21
    • Brodie, A.M.1    Longcope, C.2
  • 26
    • 0018743823 scopus 로고
    • Aromatase inhibitors. IV. Regression of hormone-dependent, mammary tumors in the rat with 4-acetoxy-4-androstene-3,17-dione
    • Brodie A.M., Marsh D., Brodie H.J. Aromatase inhibitors. IV. Regression of hormone-dependent, mammary tumors in the rat with 4-acetoxy-4-androstene-3,17-dione. Journal of Steroid Biochemistry 1979, 10(4):423-429.
    • (1979) Journal of Steroid Biochemistry , vol.10 , Issue.4 , pp. 423-429
    • Brodie, A.M.1    Marsh, D.2    Brodie, H.J.3
  • 27
    • 0017755181 scopus 로고
    • The effect of an aromatase inhibitor, 4-hydroxy-4-androstene-3,17-dione, on estrogen-dependent processes in reproduction and breast cancer
    • Brodie A.M., Schwarzel W.C., Shaikh A.A., Brodie H.J. The effect of an aromatase inhibitor, 4-hydroxy-4-androstene-3,17-dione, on estrogen-dependent processes in reproduction and breast cancer. Endocrinology 1977, 100(6):1684-1695.
    • (1977) Endocrinology , vol.100 , Issue.6 , pp. 1684-1695
    • Brodie, A.M.1    Schwarzel, W.C.2    Shaikh, A.A.3    Brodie, H.J.4
  • 28
    • 0030667676 scopus 로고    scopus 로고
    • Molecular basis of agonism and antagonism in the oestrogen receptor
    • Brzozowski A.M., Pike A.C., Dauter Z., Hubbard R.E., Bonn T., Engstrom O., et al. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 1997, 389(6652):753-758.
    • (1997) Nature , vol.389 , Issue.6652 , pp. 753-758
    • Brzozowski, A.M.1    Pike, A.C.2    Dauter, Z.3    Hubbard, R.E.4    Bonn, T.5    Engstrom, O.6
  • 29
    • 70450190156 scopus 로고    scopus 로고
    • Canadian Cancer Statistics
    • Canadian Cancer Statistics (2012). Canadian Cancer Society.
    • (2012) Canadian Cancer Society
  • 30
    • 0037830132 scopus 로고    scopus 로고
    • Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: The Women's Health Initiative Randomized Trial
    • Chlebowski R.T., Hendrix S.L., Langer R.D., Stefanick M.L., Gass M., Lane D., et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: The Women's Health Initiative Randomized Trial. Journal of the American Medical Association 2003, 289(24):3243-3253.
    • (2003) Journal of the American Medical Association , vol.289 , Issue.24 , pp. 3243-3253
    • Chlebowski, R.T.1    Hendrix, S.L.2    Langer, R.D.3    Stefanick, M.L.4    Gass, M.5    Lane, D.6
  • 31
    • 33947510501 scopus 로고    scopus 로고
    • Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: Update of study BIG 1-98
    • Coates A.S., Keshaviah A., Thurlimann B., Mouridsen H., Mauriac L., Forbes J.F., et al. Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: Update of study BIG 1-98. Journal of Clinical Oncology 2007, 25(5):486-492.
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.5 , pp. 486-492
    • Coates, A.S.1    Keshaviah, A.2    Thurlimann, B.3    Mouridsen, H.4    Mauriac, L.5    Forbes, J.F.6
  • 32
    • 0015069359 scopus 로고
    • A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474
    • Cole M.P., Jones C.T., Todd I.D. A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474. British Journal of Cancer 1971, 25(2):270-275.
    • (1971) British Journal of Cancer , vol.25 , Issue.2 , pp. 270-275
    • Cole, M.P.1    Jones, C.T.2    Todd, I.D.3
  • 33
    • 0022338828 scopus 로고
    • Consensus conference Adjuvant chemotherapy for breast cancer
    • Consensus conference Adjuvant chemotherapy for breast cancer. Journal of the American Medical Association 1985, 254(24):3461-3463.
    • (1985) Journal of the American Medical Association , vol.254 , Issue.24 , pp. 3461-3463
  • 34
    • 0021712326 scopus 로고
    • 4-Hydroxyandrostenedione in treatment of postmenopausal patients with advanced breast cancer
    • Coombes R.C., Goss P., Dowsett M., Gazet J.C., Brodie A. 4-Hydroxyandrostenedione in treatment of postmenopausal patients with advanced breast cancer. The Lancet 1984, 2(8414):1237-1239.
    • (1984) The Lancet , vol.2 , Issue.8414 , pp. 1237-1239
    • Coombes, R.C.1    Goss, P.2    Dowsett, M.3    Gazet, J.C.4    Brodie, A.5
  • 35
    • 10744223655 scopus 로고    scopus 로고
    • A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer
    • Coombes R.C., Hall E., Gibson L.J., Paridaens R., Jassem J., Delozier T., et al. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. The New England Journal of Medicine 2004, 350(11):1081-1092.
    • (2004) The New England Journal of Medicine , vol.350 , Issue.11 , pp. 1081-1092
    • Coombes, R.C.1    Hall, E.2    Gibson, L.J.3    Paridaens, R.4    Jassem, J.5    Delozier, T.6
  • 37
    • 84857914293 scopus 로고    scopus 로고
    • Breast tenderness and breast cancer risk in the estrogen plus progestin and estrogen-alone women's health initiative clinical trials
    • Crandall C.J., Aragaki A.K., Cauley J.A., McTiernan A., Manson J.E., Anderson G., et al. Breast tenderness and breast cancer risk in the estrogen plus progestin and estrogen-alone women's health initiative clinical trials. Breast Cancer Research and Treatment 2012, 132(1):275-285.
    • (2012) Breast Cancer Research and Treatment , vol.132 , Issue.1 , pp. 275-285
    • Crandall, C.J.1    Aragaki, A.K.2    Cauley, J.A.3    McTiernan, A.4    Manson, J.E.5    Anderson, G.6
  • 38
    • 0033575083 scopus 로고    scopus 로고
    • The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation
    • Cummings S.R., Eckert S., Krueger K.A., Grady D., Powles T.J., Cauley J.A., et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation. Journal of the American Medical Association 1999, 281(23):2189-2197.
    • (1999) Journal of the American Medical Association , vol.281 , Issue.23 , pp. 2189-2197
    • Cummings, S.R.1    Eckert, S.2    Krueger, K.A.3    Grady, D.4    Powles, T.J.5    Cauley, J.A.6
  • 40
    • 0347450835 scopus 로고
    • Tamoxifen and contralateral breast cancer
    • Cuzick J., Baum M. Tamoxifen and contralateral breast cancer. The Lancet 1985, 2(8449):282.
    • (1985) The Lancet , vol.2 , Issue.8449 , pp. 282
    • Cuzick, J.1    Baum, M.2
  • 41
    • 33646440021 scopus 로고    scopus 로고
    • Re: Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study
    • author reply 643-644
    • Cuzick J., Forbes J.F., Howell A. Re: Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study. Journal of the National Cancer Institute 2006, 98(9):643. author reply 643-644.
    • (2006) Journal of the National Cancer Institute , vol.98 , Issue.9 , pp. 643
    • Cuzick, J.1    Forbes, J.F.2    Howell, A.3
  • 42
    • 85203363507 scopus 로고    scopus 로고
    • Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: Patient-level meta-analysis of randomised trials
    • Davies C., Godwin J., Gray R., Clarke M., Cutter D., Darby S., et al. Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: Patient-level meta-analysis of randomised trials. The Lancet 2011, 378(9793):771-784.
    • (2011) The Lancet , vol.378 , Issue.9793 , pp. 771-784
    • Davies, C.1    Godwin, J.2    Gray, R.3    Clarke, M.4    Cutter, D.5    Darby, S.6
  • 44
    • 0033559352 scopus 로고    scopus 로고
    • Modifications of benzylphenoxy ethanamine antiestrogen molecules: Influence affinity for antiestrogen binding site (AEBS) and cell cytotoxicity
    • Delarue F., Kedjouar B., Mesange F., Bayard F., Faye J.C., Poirot M. Modifications of benzylphenoxy ethanamine antiestrogen molecules: Influence affinity for antiestrogen binding site (AEBS) and cell cytotoxicity. Biochemical Pharmacology 1999, 57(6):657-661.
    • (1999) Biochemical Pharmacology , vol.57 , Issue.6 , pp. 657-661
    • Delarue, F.1    Kedjouar, B.2    Mesange, F.3    Bayard, F.4    Faye, J.C.5    Poirot, M.6
  • 45
    • 78049523306 scopus 로고    scopus 로고
    • Results of the CONFIRM phase III trial comparing fulvestrant 250mg with fulvestrant 500mg in postmenopausal women with estrogen receptor-positive advanced breast cancer
    • Di Leo A., Jerusalem G., Petruzelka L., Torres R., Bondarenko I.N., Khasanov R., et al. Results of the CONFIRM phase III trial comparing fulvestrant 250mg with fulvestrant 500mg in postmenopausal women with estrogen receptor-positive advanced breast cancer. Journal of Clinical Oncology 2010, 28(30):4594-4600.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.30 , pp. 4594-4600
    • Di Leo, A.1    Jerusalem, G.2    Petruzelka, L.3    Torres, R.4    Bondarenko, I.N.5    Khasanov, R.6
  • 46
    • 70449554041 scopus 로고    scopus 로고
    • Prevalent breast cancer patients with a homozygous mutant status for CYP2D6*4: Response and biomarkers in tamoxifen users
    • Dieudonne A.S., Lambrechts D., Claes B., Vandorpe T., Wildiers H., Timmerman D., et al. Prevalent breast cancer patients with a homozygous mutant status for CYP2D6*4: Response and biomarkers in tamoxifen users. Breast Cancer Research and Treatment 2009, 118(3):531-538.
    • (2009) Breast Cancer Research and Treatment , vol.118 , Issue.3 , pp. 531-538
    • Dieudonne, A.S.1    Lambrechts, D.2    Claes, B.3    Vandorpe, T.4    Wildiers, H.5    Timmerman, D.6
  • 47
    • 50349133151 scopus 로고
    • Biological effects of the synthetic oestrogenic substance 4:4'-dihydroxy-alpha:beta-diethylstilbene
    • Dodds E. Biological effects of the synthetic oestrogenic substance 4:4'-dihydroxy-alpha:beta-diethylstilbene. The Lancet 1938, 232(6015):1389-1391.
    • (1938) The Lancet , vol.232 , Issue.6015 , pp. 1389-1391
    • Dodds, E.1
  • 48
    • 0001242280 scopus 로고
    • Oestrogenic activity of esters of diethyl stilboestrol
    • Dodds E.C., Goldberg L., Lawson W., Robinson R. Oestrogenic activity of esters of diethyl stilboestrol. Nature 1938, 142(3587):211-212.
    • (1938) Nature , vol.142 , Issue.3587 , pp. 211-212
    • Dodds, E.C.1    Goldberg, L.2    Lawson, W.3    Robinson, R.4
  • 49
    • 75749092296 scopus 로고    scopus 로고
    • Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen
    • Dowsett M., Cuzick J., Ingle J., Coates A., Forbes J., Bliss J., et al. Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen. Journal of Clinical Oncology 2010, 28(3):509-518.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.3 , pp. 509-518
    • Dowsett, M.1    Cuzick, J.2    Ingle, J.3    Coates, A.4    Forbes, J.5    Bliss, J.6
  • 50
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials. Early Breast Cancer Trialisits' Collaborative Group
    • EBCTCG
    • EBCTCG Tamoxifen for early breast cancer: An overview of the randomised trials. Early Breast Cancer Trialisits' Collaborative Group. The Lancet 1998, 351(9114):1451-1467.
    • (1998) The Lancet , vol.351 , Issue.9114 , pp. 1451-1467
  • 51
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • EBCTCG
    • EBCTCG Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials. The Lancet 2005, 365(9472):1687-1717.
    • (2005) The Lancet , vol.365 , Issue.9472 , pp. 1687-1717
  • 53
    • 68949102467 scopus 로고    scopus 로고
    • Lower-dose vs. high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: A phase 2 randomized study
    • Ellis M.J., Gao F., Dehdashti F., Jeffe D.B., Marcom P.K., Carey L.A., et al. Lower-dose vs. high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: A phase 2 randomized study. Journal of the American Medical Association 2009, 302(7):774-780.
    • (2009) Journal of the American Medical Association , vol.302 , Issue.7 , pp. 774-780
    • Ellis, M.J.1    Gao, F.2    Dehdashti, F.3    Jeffe, D.B.4    Marcom, P.K.5    Carey, L.A.6
  • 54
    • 0033581212 scopus 로고    scopus 로고
    • Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: Results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators
    • Ettinger B., Black D.M., Mitlak B.H., Knickerbocker R.K., Nickelsen T., Genant H.K., et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: Results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. Journal of the American Medical Association 1999, 282(7):637-645.
    • (1999) Journal of the American Medical Association , vol.282 , Issue.7 , pp. 637-645
    • Ettinger, B.1    Black, D.M.2    Mitlak, B.H.3    Knickerbocker, R.K.4    Nickelsen, T.5    Genant, H.K.6
  • 55
    • 84880265637 scopus 로고    scopus 로고
    • An emerging principle: Selective nuclear receptor modulators
    • Imperial College Press, London, V.C. Jordan (Ed.)
    • Fan P., Jordan V.C. An emerging principle: Selective nuclear receptor modulators. Estrogen actions, SERMs, and women's health 2013, Imperial College Press, London. V.C. Jordan (Ed.).
    • (2013) Estrogen actions, SERMs, and women's health
    • Fan, P.1    Jordan, V.C.2
  • 56
    • 84869489330 scopus 로고    scopus 로고
    • Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines
    • Fan P., McDaniel R.E., Kim H.R., Clagett D., Haddad B., Jordan V.C. Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines. European Journal of Cancer 2012, 48:3488-3498.
    • (2012) European Journal of Cancer , vol.48 , pp. 3488-3498
    • Fan, P.1    McDaniel, R.E.2    Kim, H.R.3    Clagett, D.4    Haddad, B.5    Jordan, V.C.6
  • 58
  • 59
    • 0024506261 scopus 로고
    • A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors
    • Fisher B., Costantino J., Redmond C., Poisson R., Bowman D., Couture J., et al. A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors. The New England Journal of Medicine 1989, 320(8):479-484.
    • (1989) The New England Journal of Medicine , vol.320 , Issue.8 , pp. 479-484
    • Fisher, B.1    Costantino, J.2    Redmond, C.3    Poisson, R.4    Bowman, D.5    Couture, J.6
  • 60
    • 27944492407 scopus 로고    scopus 로고
    • Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study
    • Fisher B., Costantino J.P., Wickerham D.L., Cecchini R.S., Cronin W.M., Robidoux A., et al. Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study. Journal of the National Cancer Institute 2005, 97(22):1652-1662.
    • (2005) Journal of the National Cancer Institute , vol.97 , Issue.22 , pp. 1652-1662
    • Fisher, B.1    Costantino, J.P.2    Wickerham, D.L.3    Cecchini, R.S.4    Cronin, W.M.5    Robidoux, A.6
  • 62
    • 0002430885 scopus 로고
    • Studies with tritium-labelled hexoestrol in advanced breast cancer. Comparison of tissue accumulation of hexoestrol with response to bilateral adrenalectomy and oophorectomy
    • Folca P.J., Glascock R.F., Irvine W.T. Studies with tritium-labelled hexoestrol in advanced breast cancer. Comparison of tissue accumulation of hexoestrol with response to bilateral adrenalectomy and oophorectomy. The Lancet 1961, 2(7206):796-798.
    • (1961) The Lancet , vol.2 , Issue.7206 , pp. 796-798
    • Folca, P.J.1    Glascock, R.F.2    Irvine, W.T.3
  • 64
    • 0021618186 scopus 로고
    • The pharmacology and clinical uses of tamoxifen
    • Furr B.J., Jordan V.C. The pharmacology and clinical uses of tamoxifen. Pharmacology and Therapeutics 1984, 25(2):127-205.
    • (1984) Pharmacology and Therapeutics , vol.25 , Issue.2 , pp. 127-205
    • Furr, B.J.1    Jordan, V.C.2
  • 65
    • 0010320958 scopus 로고
    • Selective accumulation of tritium-labelled hexoestrol by the reproductive organs of immature female goats and sheep
    • Glascock R.F., Hoekstra W.G. Selective accumulation of tritium-labelled hexoestrol by the reproductive organs of immature female goats and sheep. The Biochemical Journal 1959, 72:673-682.
    • (1959) The Biochemical Journal , vol.72 , pp. 673-682
    • Glascock, R.F.1    Hoekstra, W.G.2
  • 67
    • 7444259675 scopus 로고    scopus 로고
    • A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer
    • Goss P.E., Ingle J.N., Martino S., Robert N.J., Muss H.B., Piccart M.J., et al. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. The New England Journal of Medicine 2003, 349(19):1793-1802.
    • (2003) The New England Journal of Medicine , vol.349 , Issue.19 , pp. 1793-1802
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3    Robert, N.J.4    Muss, H.B.5    Piccart, M.J.6
  • 68
    • 24744450378 scopus 로고    scopus 로고
    • Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: Updated findings from NCIC CTG MA.17
    • Goss P.E., Ingle J.N., Martino S., Robert N.J., Muss H.B., Piccart M.J., et al. Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: Updated findings from NCIC CTG MA.17. Journal of the National Cancer Institute 2005, 97(17):1262-1271.
    • (2005) Journal of the National Cancer Institute , vol.97 , Issue.17 , pp. 1262-1271
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3    Robert, N.J.4    Muss, H.B.5    Piccart, M.J.6
  • 69
    • 0024319781 scopus 로고
    • Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens
    • Gottardis M.M., Jiang S.Y., Jeng M.H., Jordan V.C. Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens. Cancer Research 1989, 49(15):4090-4093.
    • (1989) Cancer Research , vol.49 , Issue.15 , pp. 4090-4093
    • Gottardis, M.M.1    Jiang, S.Y.2    Jeng, M.H.3    Jordan, V.C.4
  • 70
    • 0023229345 scopus 로고
    • Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model
    • Gottardis M.M., Jordan V.C. Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model. Cancer Research 1987, 47(15):4020-4024.
    • (1987) Cancer Research , vol.47 , Issue.15 , pp. 4020-4024
    • Gottardis, M.M.1    Jordan, V.C.2
  • 71
    • 0023760993 scopus 로고
    • Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration
    • Gottardis M.M., Jordan V.C. Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration. Cancer Research 1988, 48(18):5183-5187.
    • (1988) Cancer Research , vol.48 , Issue.18 , pp. 5183-5187
    • Gottardis, M.M.1    Jordan, V.C.2
  • 72
    • 0025300620 scopus 로고
    • Effect of steroidal and nonsteroidal antiestrogens on the growth of a tamoxifen-stimulated human endometrial carcinoma (EnCa101) in athymic mice
    • Gottardis M.M., Ricchio M.E., Satyaswaroop P.G., Jordan V.C. Effect of steroidal and nonsteroidal antiestrogens on the growth of a tamoxifen-stimulated human endometrial carcinoma (EnCa101) in athymic mice. Cancer Research 1990, 50(11):3189-3192.
    • (1990) Cancer Research , vol.50 , Issue.11 , pp. 3189-3192
    • Gottardis, M.M.1    Ricchio, M.E.2    Satyaswaroop, P.G.3    Jordan, V.C.4
  • 73
    • 0023915865 scopus 로고
    • Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse
    • Gottardis M.M., Robinson S.P., Satyaswaroop P.G., Jordan V.C. Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse. Cancer Research 1988, 48(4):812-815.
    • (1988) Cancer Research , vol.48 , Issue.4 , pp. 812-815
    • Gottardis, M.M.1    Robinson, S.P.2    Satyaswaroop, P.G.3    Jordan, V.C.4
  • 74
    • 0024316533 scopus 로고
    • Differential ability of antiestrogens to stimulate breast cancer cell (MCF-7) growth in vivo and in vitro
    • Gottardis M.M., Wagner R.J., Borden E.C., Jordan V.C. Differential ability of antiestrogens to stimulate breast cancer cell (MCF-7) growth in vivo and in vitro. Cancer Research 1989, 49(17):4765-4769.
    • (1989) Cancer Research , vol.49 , Issue.17 , pp. 4765-4769
    • Gottardis, M.M.1    Wagner, R.J.2    Borden, E.C.3    Jordan, V.C.4
  • 75
    • 0027201501 scopus 로고
    • Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats
    • Greaves P., Goonetilleke R., Nunn G., Topham J., Orton T. Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats. Cancer Research 1993, 53(17):3919-3924.
    • (1993) Cancer Research , vol.53 , Issue.17 , pp. 3919-3924
    • Greaves, P.1    Goonetilleke, R.2    Nunn, G.3    Topham, J.4    Orton, T.5
  • 77
    • 0014864330 scopus 로고
    • David A. Karnofsky memorial lecture. Thoughts on chemical therapy
    • Haddow A. David A. Karnofsky memorial lecture. Thoughts on chemical therapy. Cancer 1970, 26(4):737-754.
    • (1970) Cancer , vol.26 , Issue.4 , pp. 737-754
    • Haddow, A.1
  • 79
    • 0027428568 scopus 로고
    • Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl:CD(BR) rats
    • Hard G.C., Latropoulos M.J., Jordan K., Radi L., Kaltenberg O.P., Imondi A.R., et al. Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl:CD(BR) rats. Cancer Research 1993, 53(19):4534-4541.
    • (1993) Cancer Research , vol.53 , Issue.19 , pp. 4534-4541
    • Hard, G.C.1    Latropoulos, M.J.2    Jordan, K.3    Radi, L.4    Kaltenberg, O.P.5    Imondi, A.R.6
  • 80
    • 0014039539 scopus 로고
    • Mode of action of I.C.I. 46,474 in preventing implantation in rats
    • Harper M.J., Walpole A.L. Mode of action of I.C.I. 46,474 in preventing implantation in rats. The Journal of Endocrinology 1967, 37(1):83-92.
    • (1967) The Journal of Endocrinology , vol.37 , Issue.1 , pp. 83-92
    • Harper, M.J.1    Walpole, A.L.2
  • 81
    • 0014053604 scopus 로고
    • A new derivative of triphenylethylene: Effect on implantation and mode of action in rats
    • Harper M.J., Walpole A.L. A new derivative of triphenylethylene: Effect on implantation and mode of action in rats. Journal of Reproduction and Fertility 1967, 13(1):101-119.
    • (1967) Journal of Reproduction and Fertility , vol.13 , Issue.1 , pp. 101-119
    • Harper, M.J.1    Walpole, A.L.2
  • 83
    • 0027984552 scopus 로고
    • Alterations in transforming growth factor-alpha and -beta production and cell responsiveness during the progression of MCF-7 human breast cancer cells to estrogen-autonomous growth
    • Herman M.E., Katzenellenbogen B.S. Alterations in transforming growth factor-alpha and -beta production and cell responsiveness during the progression of MCF-7 human breast cancer cells to estrogen-autonomous growth. Cancer Research 1994, 54(22):5867-5874.
    • (1994) Cancer Research , vol.54 , Issue.22 , pp. 5867-5874
    • Herman, M.E.1    Katzenellenbogen, B.S.2
  • 84
    • 11444251764 scopus 로고    scopus 로고
    • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer
    • Howell A., Cuzick J., Baum M., Buzdar A., Dowsett M., Forbes J.F., et al. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. The Lancet 2005, 365(9453):60-62.
    • (2005) The Lancet , vol.365 , Issue.9453 , pp. 60-62
    • Howell, A.1    Cuzick, J.2    Baum, M.3    Buzdar, A.4    Dowsett, M.5    Forbes, J.F.6
  • 85
    • 2442648038 scopus 로고    scopus 로고
    • Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: A multinational, double-blind, randomized trial
    • Howell A., Robertson J.F., Abram P., Lichinitser M.R., Elledge R., Bajetta E., et al. Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: A multinational, double-blind, randomized trial. Journal of Clinical Oncology 2004, 22(9):1605-1613.
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.9 , pp. 1605-1613
    • Howell, A.1    Robertson, J.F.2    Abram, P.3    Lichinitser, M.R.4    Elledge, R.5    Bajetta, E.6
  • 87
    • 33646874546 scopus 로고    scopus 로고
    • The molecular portraits of breast tumors are conserved across microarray platforms
    • Hu Z., Fan C., Oh D.S., Marron J.S., He X., Qaqish B.F., et al. The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics 2006, 7:96.
    • (2006) BMC Genomics , vol.7 , pp. 96
    • Hu, Z.1    Fan, C.2    Oh, D.S.3    Marron, J.S.4    He, X.5    Qaqish, B.F.6
  • 88
    • 79959593177 scopus 로고    scopus 로고
    • Proteomic analysis of pathways involved in estrogen-induced growth and apoptosis of breast cancer cells
    • Hu Z.Z., Kagan B.L., Ariazi E.A., Rosenthal D.S., Zhang L., Li J.V., et al. Proteomic analysis of pathways involved in estrogen-induced growth and apoptosis of breast cancer cells. PLoS One 2011, 6(6):e20410.
    • (2011) PLoS One , vol.6 , Issue.6
    • Hu, Z.Z.1    Kagan, B.L.2    Ariazi, E.A.3    Rosenthal, D.S.4    Zhang, L.5    Li, J.V.6
  • 89
    • 0000468691 scopus 로고
    • Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression
    • Huggins C., Grand L.C., Brillantes F.P. Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression. Nature 1961, 189:204-207.
    • (1961) Nature , vol.189 , pp. 204-207
    • Huggins, C.1    Grand, L.C.2    Brillantes, F.P.3
  • 90
    • 84880278668 scopus 로고    scopus 로고
    • INCA
    • Instituto Nacional de Cancer, Rio de Janeiro
    • INCA A Situacao do Cancer no Brasil 2006, Instituto Nacional de Cancer, Rio de Janeiro.
    • (2006) A Situacao do Cancer no Brasil
  • 91
    • 0019382847 scopus 로고
    • Randomized clinical trial of diethylstilbestrol versus tamoxifen in postmenopausal women with advanced breast cancer
    • Ingle J.N., Ahmann D.L., Green S.J., Edmonson J.H., Bisel H.F., Kvols L.K., et al. Randomized clinical trial of diethylstilbestrol versus tamoxifen in postmenopausal women with advanced breast cancer. The New England Journal of Medicine 1981, 304(1):16-21.
    • (1981) The New England Journal of Medicine , vol.304 , Issue.1 , pp. 16-21
    • Ingle, J.N.1    Ahmann, D.L.2    Green, S.J.3    Edmonson, J.H.4    Bisel, H.F.5    Kvols, L.K.6
  • 92
    • 33744791784 scopus 로고    scopus 로고
    • Novel chromene-derived selective estrogen receptor modulators useful for alleviating hot flushes and vaginal dryness
    • Jain N., Kanojia R.M., Xu J., Jian-Zhong G., Pacia E., Lai M.T., et al. Novel chromene-derived selective estrogen receptor modulators useful for alleviating hot flushes and vaginal dryness. Journal of Medicinal Chemistry 2006, 49(11):3056-3059.
    • (2006) Journal of Medicinal Chemistry , vol.49 , Issue.11 , pp. 3056-3059
    • Jain, N.1    Kanojia, R.M.2    Xu, J.3    Jian-Zhong, G.4    Pacia, E.5    Lai, M.T.6
  • 93
    • 72549086337 scopus 로고    scopus 로고
    • Identification and structure-activity relationships of chromene-derived selective estrogen receptor modulators for treatment of postmenopausal symptoms
    • Jain N., Xu J., Kanojia R.M., Du F., Jian-Zhong G., Pacia E., et al. Identification and structure-activity relationships of chromene-derived selective estrogen receptor modulators for treatment of postmenopausal symptoms. Journal of Medicinal Chemistry 2009, 52(23):7544-7569.
    • (2009) Journal of Medicinal Chemistry , vol.52 , Issue.23 , pp. 7544-7569
    • Jain, N.1    Xu, J.2    Kanojia, R.M.3    Du, F.4    Jian-Zhong, G.5    Pacia, E.6
  • 96
    • 0017078344 scopus 로고
    • Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata
    • Jordan V.C. Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata. European Journal of Cancer 1976, 12(6):419-424.
    • (1976) European Journal of Cancer , vol.12 , Issue.6 , pp. 419-424
    • Jordan, V.C.1
  • 97
    • 0002420533 scopus 로고
    • Use of the DMBA-induced rat mammary carcinoma system for the evaluation of tamoxifen treatment as a potential adjuvant therapy
    • October
    • Jordan V.C. Use of the DMBA-induced rat mammary carcinoma system for the evaluation of tamoxifen treatment as a potential adjuvant therapy. Reviews on Endocrine-Related Cancer 1978, (October Suppl.):49-55.
    • (1978) Reviews on Endocrine-Related Cancer , Issue.SUPPL. , pp. 49-55
    • Jordan, V.C.1
  • 98
    • 0021709492 scopus 로고
    • Biochemical pharmacology of antiestrogen action
    • Jordan V.C. Biochemical pharmacology of antiestrogen action. Pharmacological Reviews 1984, 36(4):245-276.
    • (1984) Pharmacological Reviews , vol.36 , Issue.4 , pp. 245-276
    • Jordan, V.C.1
  • 99
    • 0031961072 scopus 로고    scopus 로고
    • Chemotherapy is antihormonal therapy-how much proof doOncologists need?
    • Jordan V.C. Chemotherapy is antihormonal therapy-how much proof doOncologists need?. European Journal of Cancer 1998, 34(5):606-608.
    • (1998) European Journal of Cancer , vol.34 , Issue.5 , pp. 606-608
    • Jordan, V.C.1
  • 100
    • 0035421182 scopus 로고    scopus 로고
    • Selective estrogen receptor modulation: A personal perspective
    • Jordan V.C. Selective estrogen receptor modulation: A personal perspective. Cancer Research 2001, 61(15):5683-5687.
    • (2001) Cancer Research , vol.61 , Issue.15 , pp. 5683-5687
    • Jordan, V.C.1
  • 101
    • 0037435046 scopus 로고    scopus 로고
    • Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions
    • Jordan V.C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions. Journal of Medicinal Chemistry 2003, 46(6):883-908.
    • (2003) Journal of Medicinal Chemistry , vol.46 , Issue.6 , pp. 883-908
    • Jordan, V.C.1
  • 102
    • 0037468902 scopus 로고    scopus 로고
    • Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents
    • Jordan V.C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents. Journal of Medicinal Chemistry 2003, 46(7):1081-1111.
    • (2003) Journal of Medicinal Chemistry , vol.46 , Issue.7 , pp. 1081-1111
    • Jordan, V.C.1
  • 103
    • 0037364074 scopus 로고    scopus 로고
    • Tamoxifen: A most unlikely pioneering medicine
    • Jordan V.C. Tamoxifen: A most unlikely pioneering medicine. Nature Reviews. Drug Discovery 2003, 2(3):205-213.
    • (2003) Nature Reviews. Drug Discovery , vol.2 , Issue.3 , pp. 205-213
    • Jordan, V.C.1
  • 104
    • 1642544604 scopus 로고    scopus 로고
    • Selective estrogen receptor modulation: Concept and consequences in cancer
    • Jordan V.C. Selective estrogen receptor modulation: Concept and consequences in cancer. Cancer Cell 2004, 5(3):207-213.
    • (2004) Cancer Cell , vol.5 , Issue.3 , pp. 207-213
    • Jordan, V.C.1
  • 105
    • 30444434216 scopus 로고    scopus 로고
    • Tamoxifen (ICI46,474) as a targeted therapy to treat and prevent breast cancer
    • Jordan V.C. Tamoxifen (ICI46,474) as a targeted therapy to treat and prevent breast cancer. British Journal of Pharmacology 2006, 147(Suppl. 1):S269-S276.
    • (2006) British Journal of Pharmacology , vol.147 , Issue.SUPPL. 1
    • Jordan, V.C.1
  • 106
    • 46449134193 scopus 로고    scopus 로고
    • The 38th David A. Karnofsky lecture: The paradoxical actions of estrogen in breast cancer-Survival or death?
    • Jordan V.C. The 38th David A. Karnofsky lecture: The paradoxical actions of estrogen in breast cancer-Survival or death?. Journal of Clinical Oncology 2008, 26(18):3073-3082.
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.18 , pp. 3073-3082
    • Jordan, V.C.1
  • 107
    • 37149028451 scopus 로고    scopus 로고
    • Tamoxifen: Catalyst for the change to targeted therapy
    • Jordan V.C. Tamoxifen: Catalyst for the change to targeted therapy. European Journal of Cancer 2008, 44(1):30-38.
    • (2008) European Journal of Cancer , vol.44 , Issue.1 , pp. 30-38
    • Jordan, V.C.1
  • 108
    • 0018906517 scopus 로고
    • Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model
    • Jordan V.C., Allen K.E. Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model. European Journal of Cancer 1980, 16(2):239-251.
    • (1980) European Journal of Cancer , vol.16 , Issue.2 , pp. 239-251
    • Jordan, V.C.1    Allen, K.E.2
  • 109
    • 0019122379 scopus 로고
    • Pharmacology of tamoxifen in laboratory animals
    • Jordan V.C., Allen K.E., Dix C.J. Pharmacology of tamoxifen in laboratory animals. Cancer Treatment Reports 1980, 64(6-7):745-759.
    • (1980) Cancer Treatment Reports , vol.64 , Issue.6-7 , pp. 745-759
    • Jordan, V.C.1    Allen, K.E.2    Dix, C.J.3
  • 110
    • 0020691322 scopus 로고
    • Determination and pharmacology of a new hydroxylated metabolite of tamoxifen observed in patient sera during therapy for advanced breast cancer
    • Jordan V.C., Bain R.R., Brown R.R., Gosden B., Santos M.A. Determination and pharmacology of a new hydroxylated metabolite of tamoxifen observed in patient sera during therapy for advanced breast cancer. Cancer Research 1983, 43(3):1446-1450.
    • (1983) Cancer Research , vol.43 , Issue.3 , pp. 1446-1450
    • Jordan, V.C.1    Bain, R.R.2    Brown, R.R.3    Gosden, B.4    Santos, M.A.5
  • 111
    • 0017665570 scopus 로고
    • A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity
    • Jordan V.C., Collins M.M., Rowsby L., Prestwich G. A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity. The Journal of Endocrinology 1977, 75(2):305-316.
    • (1977) The Journal of Endocrinology , vol.75 , Issue.2 , pp. 305-316
    • Jordan, V.C.1    Collins, M.M.2    Rowsby, L.3    Prestwich, G.4
  • 112
    • 0002487846 scopus 로고
    • The effectiveness of longterm treatment in a laboratory model for adjuvant hormone therapy of breast cancer
    • Grune and Stratton, New York, S.E. Salmone, S.E. Jones (Eds.)
    • Jordan V.C., Dix C.J., Allen K.E. The effectiveness of longterm treatment in a laboratory model for adjuvant hormone therapy of breast cancer. Adjuvant therapy of cancer II 1979, 19-26. Grune and Stratton, New York. S.E. Salmone, S.E. Jones (Eds.).
    • (1979) Adjuvant therapy of cancer II , pp. 19-26
    • Jordan, V.C.1    Dix, C.J.2    Allen, K.E.3
  • 114
    • 0016638259 scopus 로고
    • Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor
    • Jordan V.C., Koerner S. Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor. European Journal of Cancer 1975, 11(3):205-206.
    • (1975) European Journal of Cancer , vol.11 , Issue.3 , pp. 205-206
    • Jordan, V.C.1    Koerner, S.2
  • 115
    • 0037036684 scopus 로고    scopus 로고
    • Re: Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17 beta-estradiol and the two faces of Janus: Sex steroids as mediators of both cell proliferation and cell death
    • author reply 1173-1175
    • Jordan V.C., Liu H., Dardes R. Re: Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17 beta-estradiol and the two faces of Janus: Sex steroids as mediators of both cell proliferation and cell death. Journal of the National Cancer Institute 2002, 94(15):1173. author reply 1173-1175.
    • (2002) Journal of the National Cancer Institute , vol.94 , Issue.15 , pp. 1173
    • Jordan, V.C.1    Liu, H.2    Dardes, R.3
  • 119
    • 0023263237 scopus 로고
    • Species-specific pharmacology of antiestrogens: Role of metabolism
    • Jordan V.C., Robinson S.P. Species-specific pharmacology of antiestrogens: Role of metabolism. Federation Proceedings 1987, 46(5):1870-1874.
    • (1987) Federation Proceedings , vol.46 , Issue.5 , pp. 1870-1874
    • Jordan, V.C.1    Robinson, S.P.2
  • 122
    • 77949370016 scopus 로고    scopus 로고
    • A randomized, placebo- and active-controlled trial of bazedoxifene/conjugated estrogens for treatment of moderate to severe vulvar/vaginal atrophy in postmenopausal women
    • Kagan R., Williams R.S., Pan K., Mirkin S., Pickar J.H. A randomized, placebo- and active-controlled trial of bazedoxifene/conjugated estrogens for treatment of moderate to severe vulvar/vaginal atrophy in postmenopausal women. Menopause 2010, 17(2):281-289.
    • (2010) Menopause , vol.17 , Issue.2 , pp. 281-289
    • Kagan, R.1    Williams, R.S.2    Pan, K.3    Mirkin, S.4    Pickar, J.H.5
  • 123
    • 0023199060 scopus 로고
    • Proliferation, hormonal responsiveness, and estrogen receptor content of MCF-7 human breast cancer cells grown in the short-term and long-term absence of estrogens
    • Katzenellenbogen B.S., Kendra K.L., Norman M.J., Berthois Y. Proliferation, hormonal responsiveness, and estrogen receptor content of MCF-7 human breast cancer cells grown in the short-term and long-term absence of estrogens. Cancer Research 1987, 47(16):4355-4360.
    • (1987) Cancer Research , vol.47 , Issue.16 , pp. 4355-4360
    • Katzenellenbogen, B.S.1    Kendra, K.L.2    Norman, M.J.3    Berthois, Y.4
  • 124
    • 80755180912 scopus 로고    scopus 로고
    • Efficacy and safety of bazedoxifene for postmenopausal osteoporosis
    • Kawate H., Takayanagi R. Efficacy and safety of bazedoxifene for postmenopausal osteoporosis. Clinical Interventions in Aging 2011, 6:151-160.
    • (2011) Clinical Interventions in Aging , vol.6 , pp. 151-160
    • Kawate, H.1    Takayanagi, R.2
  • 125
    • 0013829730 scopus 로고
    • Hormone therapy for advanced breast cancer
    • Kennedy B.J. Hormone therapy for advanced breast cancer. Cancer 1965, 18(12):1551-1557.
    • (1965) Cancer , vol.18 , Issue.12 , pp. 1551-1557
    • Kennedy, B.J.1
  • 126
    • 70350358738 scopus 로고
    • Systemic effects of androgenic and estrogenic hormones in advanced breast cancer
    • Kennedy B.J. Systemic effects of androgenic and estrogenic hormones in advanced breast cancer. Journal of the American Geriatrics Society 1965, 13:230-235.
    • (1965) Journal of the American Geriatrics Society , vol.13 , pp. 230-235
    • Kennedy, B.J.1
  • 127
  • 128
    • 77950502100 scopus 로고    scopus 로고
    • Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients
    • Kiyotani K., Mushiroda T., Imamura C.K., Hosono N., Tsunoda T., Kubo M., et al. Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients. Journal of Clinical Oncology 2010, 28(8):1287-1293.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.8 , pp. 1287-1293
    • Kiyotani, K.1    Mushiroda, T.2    Imamura, C.K.3    Hosono, N.4    Tsunoda, T.5    Kubo, M.6
  • 129
    • 0015228433 scopus 로고
    • New synthetic agent for the induction of ovulation: Preliminary trials in women
    • Klopper A., Hall M. New synthetic agent for the induction of ovulation: Preliminary trials in women. British Medical Journal 1971, 1(5741):152-154.
    • (1971) British Medical Journal , vol.1 , Issue.5741 , pp. 152-154
    • Klopper, A.1    Hall, M.2
  • 130
    • 23844531615 scopus 로고    scopus 로고
    • Bazedoxifene acetate: A selective estrogen receptor modulator with improved selectivity
    • Komm B.S., Kharode Y.P., Bodine P.V., Harris H.A., Miller C.P., Lyttle C.R. Bazedoxifene acetate: A selective estrogen receptor modulator with improved selectivity. Endocrinology 2005, 146(9):3999-4008.
    • (2005) Endocrinology , vol.146 , Issue.9 , pp. 3999-4008
    • Komm, B.S.1    Kharode, Y.P.2    Bodine, P.V.3    Harris, H.A.4    Miller, C.P.5    Lyttle, C.R.6
  • 131
    • 60549084704 scopus 로고
    • Influence d'un facteur familial dans la production par la folliculine, de cancers mammaires chez la souris male
    • Lacassagne A. Influence d'un facteur familial dans la production par la folliculine, de cancers mammaires chez la souris male. Comptes Rendus des Seances de la Societe de Biologie et des ses Filiales (Paris) 1933, 114:427-429.
    • (1933) Comptes Rendus des Seances de la Societe de Biologie et des ses Filiales (Paris) , vol.114 , pp. 427-429
    • Lacassagne, A.1
  • 132
    • 60549097028 scopus 로고
    • A comparative study of the carcinogenic action of certain oestrogenic hormones
    • Lacassagne A. A comparative study of the carcinogenic action of certain oestrogenic hormones. American Journal of Cancer 1936, 28:735-740.
    • (1936) American Journal of Cancer , vol.28 , pp. 735-740
    • Lacassagne, A.1
  • 133
    • 84965826780 scopus 로고
    • Hormonal pathogenesis of adenocarcinoma of the breast
    • Lacassagne A. Hormonal pathogenesis of adenocarcinoma of the breast. American Journal of Cancer 1936, 27(2):217-228.
    • (1936) American Journal of Cancer , vol.27 , Issue.2 , pp. 217-228
    • Lacassagne, A.1
  • 134
    • 79953743574 scopus 로고    scopus 로고
    • Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: A randomized controlled trial
    • LaCroix A.Z., Chlebowski R.T., Manson J.E., Aragaki A.K., Johnson K.C., Martin L., et al. Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: A randomized controlled trial. Journal of the American Medical Association 2011, 305(13):1305-1314.
    • (2011) Journal of the American Medical Association , vol.305 , Issue.13 , pp. 1305-1314
    • LaCroix, A.Z.1    Chlebowski, R.T.2    Manson, J.E.3    Aragaki, A.K.4    Johnson, K.C.5    Martin, L.6
  • 135
    • 77956429360 scopus 로고    scopus 로고
    • The impact of CYP2D6-predicted phenotype on tamoxifen treatment outcome in patients with metastatic breast cancer
    • Lammers L.A., Mathijssen R.H., van Gelder T., Bijl M.J., de Graan A.J., Seynaeve C., et al. The impact of CYP2D6-predicted phenotype on tamoxifen treatment outcome in patients with metastatic breast cancer. British Journal of Cancer 2010, 103(6):765-771.
    • (2010) British Journal of Cancer , vol.103 , Issue.6 , pp. 765-771
    • Lammers, L.A.1    Mathijssen, R.H.2    van Gelder, T.3    Bijl, M.J.4    de Graan, A.J.5    Seynaeve, C.6
  • 137
    • 84965819865 scopus 로고
    • Further investigations on the origin of tumors in mice. III. On the part played by internal secretion in the spontaneous development of tumors
    • Lathrop A.E., Loeb L. Further investigations on the origin of tumors in mice. III. On the part played by internal secretion in the spontaneous development of tumors. Journal of Cancer Research 1916, 1(1):1-19.
    • (1916) Journal of Cancer Research , vol.1 , Issue.1 , pp. 1-19
    • Lathrop, A.E.1    Loeb, L.2
  • 139
    • 0021259498 scopus 로고
    • Randomised trial of chemo-endocrine therapy, endocrine therapy, and mastectomy alone in postmenopausal patients with operable breast cancer and axillary node metastasis
    • LBCSG
    • LBCSG Randomised trial of chemo-endocrine therapy, endocrine therapy, and mastectomy alone in postmenopausal patients with operable breast cancer and axillary node metastasis. The Lancet 1984, 1(8384):1256-1260.
    • (1984) The Lancet , vol.1 , Issue.8384 , pp. 1256-1260
  • 141
    • 0014040985 scopus 로고
    • Mammalian antifertility agents. IV. Basic 3,4-dihydronaphthalenes and 1,2,3,4-tetrahydro-1-naphthols
    • Lednicer D., Lyster S.C., Duncan G.W. Mammalian antifertility agents. IV. Basic 3,4-dihydronaphthalenes and 1,2,3,4-tetrahydro-1-naphthols. Journal of Medicinal Chemistry 1967, 10(1):78-84.
    • (1967) Journal of Medicinal Chemistry , vol.10 , Issue.1 , pp. 78-84
    • Lednicer, D.1    Lyster, S.C.2    Duncan, G.W.3
  • 142
    • 0017166858 scopus 로고
    • Nafoxidine-An antiestrogen for the treatment of breast cancer
    • Legha S.S., Slavik M., Carter S.K. Nafoxidine-An antiestrogen for the treatment of breast cancer. Cancer 1976, 38(4):1535-1541.
    • (1976) Cancer , vol.38 , Issue.4 , pp. 1535-1541
    • Legha, S.S.1    Slavik, M.2    Carter, S.K.3
  • 144
    • 70449221678 scopus 로고
    • A non-steroidal estrogen antiagonist 1-(p-2-diethylaminoethoxyphenyl)-1-phenyl-2-p-methoxyphenyl ethanol
    • Lerner L.J., Holthaus F.J., Thompson C.R. A non-steroidal estrogen antiagonist 1-(p-2-diethylaminoethoxyphenyl)-1-phenyl-2-p-methoxyphenyl ethanol. Endocrinology 1958, 63(3):295-318.
    • (1958) Endocrinology , vol.63 , Issue.3 , pp. 295-318
    • Lerner, L.J.1    Holthaus, F.J.2    Thompson, C.R.3
  • 145
    • 0025338591 scopus 로고
    • Development of antiestrogens and their use in breast cancer: Eighth Cain memorial award lecture
    • Lerner L.J., Jordan V.C. Development of antiestrogens and their use in breast cancer: Eighth Cain memorial award lecture. Cancer Research 1990, 50(14):4177-4189.
    • (1990) Cancer Research , vol.50 , Issue.14 , pp. 4177-4189
    • Lerner, L.J.1    Jordan, V.C.2
  • 146
    • 28944444552 scopus 로고    scopus 로고
    • Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation
    • Lewis J.S., Meeke K., Osipo C., Ross E.A., Kidawi N., Li T., et al. Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation. Journal of the National Cancer Institute 2005, 97(23):1746-1759.
    • (2005) Journal of the National Cancer Institute , vol.97 , Issue.23 , pp. 1746-1759
    • Lewis, J.S.1    Meeke, K.2    Osipo, C.3    Ross, E.A.4    Kidawi, N.5    Li, T.6
  • 147
    • 63849267401 scopus 로고    scopus 로고
    • Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis
    • Lewis-Wambi J.S., Kim H.R., Wambi C., Patel R., Pyle J.R., Klein-Szanto A.J., et al. Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis. Breast Cancer Research 2008, 10(6):R104.
    • (2008) Breast Cancer Research , vol.10 , Issue.6
    • Lewis-Wambi, J.S.1    Kim, H.R.2    Wambi, C.3    Patel, R.4    Pyle, J.R.5    Klein-Szanto, A.J.6
  • 148
    • 62949186374 scopus 로고    scopus 로고
    • Potential of l-buthionine sulfoximine to enhance the apoptotic action of estradiol to reverse acquired antihormonal resistance in metastatic breast cancer
    • Lewis-Wambi J.S., Swaby R., Kim H., Jordan V.C. Potential of l-buthionine sulfoximine to enhance the apoptotic action of estradiol to reverse acquired antihormonal resistance in metastatic breast cancer. The Journal of Steroid Biochemistry and Molecular Biology 2009, 114(1-2):33-39.
    • (2009) The Journal of Steroid Biochemistry and Molecular Biology , vol.114 , Issue.1-2 , pp. 33-39
    • Lewis-Wambi, J.S.1    Swaby, R.2    Kim, H.3    Jordan, V.C.4
  • 149
    • 69049083661 scopus 로고    scopus 로고
    • Efficacy of tissue-selective estrogen complex of bazedoxifene/conjugated estrogens for osteoporosis prevention in at-risk postmenopausal women
    • Lindsay R., Gallagher J.C., Kagan R., Pickar J.H., Constantine G. Efficacy of tissue-selective estrogen complex of bazedoxifene/conjugated estrogens for osteoporosis prevention in at-risk postmenopausal women. Fertility and Sterility 2009, 92(3):1045-1052.
    • (2009) Fertility and Sterility , vol.92 , Issue.3 , pp. 1045-1052
    • Lindsay, R.1    Gallagher, J.C.2    Kagan, R.3    Pickar, J.H.4    Constantine, G.5
  • 150
    • 0016740410 scopus 로고
    • Oestrogen-responsive human breast cancer in long term tissue culture
    • Lippman M.E., Bolan G. Oestrogen-responsive human breast cancer in long term tissue culture. Nature 1975, 256(5518):592-593.
    • (1975) Nature , vol.256 , Issue.5518 , pp. 592-593
    • Lippman, M.E.1    Bolan, G.2
  • 151
    • 70350772330 scopus 로고    scopus 로고
    • Additive endocrine therapy for advanced breast cancer-Back to the future
    • Lonning P.E. Additive endocrine therapy for advanced breast cancer-Back to the future. Acta Oncologica 2009, 48(8):1092-1101.
    • (2009) Acta Oncologica , vol.48 , Issue.8 , pp. 1092-1101
    • Lonning, P.E.1
  • 152
    • 0034891355 scopus 로고    scopus 로고
    • High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine therapy
    • Lonning P.E., Taylor P.D., Anker G., Iddon J., Wie L., Jorgensen L.M., et al. High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine therapy. Breast Cancer Research and Treatment 2001, 67(2):111-116.
    • (2001) Breast Cancer Research and Treatment , vol.67 , Issue.2 , pp. 111-116
    • Lonning, P.E.1    Taylor, P.D.2    Anker, G.3    Iddon, J.4    Wie, L.5    Jorgensen, L.M.6
  • 154
    • 0025324359 scopus 로고
    • Effects of tamoxifen therapy on lipid and lipoprotein levels in postmenopausal patients with node-negative breast cancer
    • Love R.R., Newcomb P.A., Wiebe D.A., Surawicz T.S., Jordan V.C., Carbone P.P., et al. Effects of tamoxifen therapy on lipid and lipoprotein levels in postmenopausal patients with node-negative breast cancer. Journal of the National Cancer Institute 1990, 82(16):1327-1332.
    • (1990) Journal of the National Cancer Institute , vol.82 , Issue.16 , pp. 1327-1332
    • Love, R.R.1    Newcomb, P.A.2    Wiebe, D.A.3    Surawicz, T.S.4    Jordan, V.C.5    Carbone, P.P.6
  • 158
    • 10644283864 scopus 로고    scopus 로고
    • Continuing outcomes relevant to Evista: Breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene
    • Martino S., Cauley J.A., Barrett-Connor E., Powles T.J., Mershon J., Disch D., et al. Continuing outcomes relevant to Evista: Breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene. Journal of the National Cancer Institute 2004, 96(23):1751-1761.
    • (2004) Journal of the National Cancer Institute , vol.96 , Issue.23 , pp. 1751-1761
    • Martino, S.1    Cauley, J.A.2    Barrett-Connor, E.3    Powles, T.J.4    Mershon, J.5    Disch, D.6
  • 161
    • 0003455268 scopus 로고
    • Raven Press, New York, W.L. McGuire, P.P. Carbone, E.P. Vollmer (Eds.)
    • Estrogen receptors in human breast cancer 1975, Raven Press, New York. W.L. McGuire, P.P. Carbone, E.P. Vollmer (Eds.).
    • (1975) Estrogen receptors in human breast cancer
  • 164
    • 77956028902 scopus 로고
    • Controlled trial of tamoxifen as adjuvant agent in management of early breast cancer. Interim analysis at four years by Nolvadex Adjuvant Trial Organisation
    • NATO
    • NATO Controlled trial of tamoxifen as adjuvant agent in management of early breast cancer. Interim analysis at four years by Nolvadex Adjuvant Trial Organisation. The Lancet 1983, 1(8319):257-261.
    • (1983) The Lancet , vol.1 , Issue.8319 , pp. 257-261
  • 166
    • 0023235522 scopus 로고
    • Human breast cancer in the athymic nude mouse: Cytostatic effects of long-term antiestrogen therapy
    • Osborne C.K., Coronado E.B., Robinson J.P. Human breast cancer in the athymic nude mouse: Cytostatic effects of long-term antiestrogen therapy. European Journal of Cancer & Clinical Oncology 1987, 23(8):1189-1196.
    • (1987) European Journal of Cancer & Clinical Oncology , vol.23 , Issue.8 , pp. 1189-1196
    • Osborne, C.K.1    Coronado, E.B.2    Robinson, J.P.3
  • 167
    • 0021958425 scopus 로고
    • Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic nude mice
    • Osborne C.K., Hobbs K., Clark G.M. Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic nude mice. Cancer Research 1985, 45(2):584-590.
    • (1985) Cancer Research , vol.45 , Issue.2 , pp. 584-590
    • Osborne, C.K.1    Hobbs, K.2    Clark, G.M.3
  • 168
    • 0037102126 scopus 로고    scopus 로고
    • Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: Results of a North American trial
    • Osborne C.K., Pippen J., Jones S.E., Parker L.M., Ellis M., Come S., et al. Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: Results of a North American trial. Journal of Clinical Oncology 2002, 20(16):3386-3395.
    • (2002) Journal of Clinical Oncology , vol.20 , Issue.16 , pp. 3386-3395
    • Osborne, C.K.1    Pippen, J.2    Jones, S.E.3    Parker, L.M.4    Ellis, M.5    Come, S.6
  • 169
    • 0344742233 scopus 로고    scopus 로고
    • Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancer
    • Osipo C., Gajdos C., Liu H., Chen B., Jordan V.C. Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancer. Journal of the National Cancer Institute 2003, 95(21):1597-1608.
    • (2003) Journal of the National Cancer Institute , vol.95 , Issue.21 , pp. 1597-1608
    • Osipo, C.1    Gajdos, C.2    Liu, H.3    Chen, B.4    Jordan, V.C.5
  • 170
    • 57749092180 scopus 로고    scopus 로고
    • Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism
    • Payre B., de Medina P., Boubekeur N., Mhamdi L., Bertrand-Michel J., Terce F., et al. Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism. Molecular Cancer Therapeutics 2008, 7(12):3707-3718.
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.12 , pp. 3707-3718
    • Payre, B.1    de Medina, P.2    Boubekeur, N.3    Mhamdi, L.4    Bertrand-Michel, J.5    Terce, F.6
  • 172
    • 0029041374 scopus 로고
    • An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein
    • Pink J.J., Jiang S.Y., Fritsch M., Jordan V.C. An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein. Cancer Research 1995, 55(12):2583-2590.
    • (1995) Cancer Research , vol.55 , Issue.12 , pp. 2583-2590
    • Pink, J.J.1    Jiang, S.Y.2    Fritsch, M.3    Jordan, V.C.4
  • 173
    • 84866395340 scopus 로고    scopus 로고
    • Bazedoxifene/conjugated estrogens for menopausal symptom treatment and osteoporosis prevention
    • Pinkerton J.V., Pickar J.H., Racketa J., Mirkin S. Bazedoxifene/conjugated estrogens for menopausal symptom treatment and osteoporosis prevention. Climacteric 2012, 15(5):411-418.
    • (2012) Climacteric , vol.15 , Issue.5 , pp. 411-418
    • Pinkerton, J.V.1    Pickar, J.H.2    Racketa, J.3    Mirkin, S.4
  • 174
    • 82555185372 scopus 로고    scopus 로고
    • Four decades of discovery in breast cancer research and treatment-An interview with V. Craig Jordan
    • Poirot M. Four decades of discovery in breast cancer research and treatment-An interview with V. Craig Jordan. The International Journal of Developmental Biology 2011, 55:703-712.
    • (2011) The International Journal of Developmental Biology , vol.55 , pp. 703-712
    • Poirot, M.1
  • 175
    • 33847773775 scopus 로고    scopus 로고
    • Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial
    • Powles T.J., Ashley S., Tidy A., Smith I.E., Dowsett M. Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial. Journal of the National Cancer Institute 2007, 99(4):283-290.
    • (2007) Journal of the National Cancer Institute , vol.99 , Issue.4 , pp. 283-290
    • Powles, T.J.1    Ashley, S.2    Tidy, A.3    Smith, I.E.4    Dowsett, M.5
  • 176
    • 0032508294 scopus 로고    scopus 로고
    • Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial
    • Powles T., Eeles R., Ashley S., Easton D., Chang J., Dowsett M., et al. Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial. The Lancet 1998, 352(9122):98-101.
    • (1998) The Lancet , vol.352 , Issue.9122 , pp. 98-101
    • Powles, T.1    Eeles, R.2    Ashley, S.3    Easton, D.4    Chang, J.5    Dowsett, M.6
  • 177
    • 0024353118 scopus 로고
    • A pilot trial to evaluate the acute toxicity and feasibility of tamoxifen for prevention of breast cancer
    • Powles T.J., Hardy J.R., Ashley S.E., Farrington G.M., Cosgrove D., Davey J.B., et al. A pilot trial to evaluate the acute toxicity and feasibility of tamoxifen for prevention of breast cancer. British Journal of Cancer 1989, 60(1):126-131.
    • (1989) British Journal of Cancer , vol.60 , Issue.1 , pp. 126-131
    • Powles, T.J.1    Hardy, J.R.2    Ashley, S.E.3    Farrington, G.M.4    Cosgrove, D.5    Davey, J.B.6
  • 178
    • 46249107674 scopus 로고    scopus 로고
    • Conjugated equine estrogens and breast cancer risk in the Women's Health Initiative clinical trial and observational study
    • Prentice R.L., Chlebowski R.T., Stefanick M.L., Manson J.E., Langer R.D., Pettinger M., et al. Conjugated equine estrogens and breast cancer risk in the Women's Health Initiative clinical trial and observational study. American Journal of Epidemiology 2008, 167(12):1407-1415.
    • (2008) American Journal of Epidemiology , vol.167 , Issue.12 , pp. 1407-1415
    • Prentice, R.L.1    Chlebowski, R.T.2    Stefanick, M.L.3    Manson, J.E.4    Langer, R.D.5    Pettinger, M.6
  • 180
    • 84859093970 scopus 로고    scopus 로고
    • CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: The breast international group 1-98 trial
    • Regan M.M., Leyland-Jones B., Bouzyk M., Pagani O., Tang W., Kammler R., et al. CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: The breast international group 1-98 trial. Journal of the National Cancer Institute 2012, 104(6):441-451.
    • (2012) Journal of the National Cancer Institute , vol.104 , Issue.6 , pp. 441-451
    • Regan, M.M.1    Leyland-Jones, B.2    Bouzyk, M.3    Pagani, O.4    Tang, W.5    Kammler, R.6
  • 181
    • 84864539047 scopus 로고    scopus 로고
    • Systematic review of lapatinib in combination with letrozole compared with other first-line treatments for hormone receptor positive (HR+) and HER2+ advanced or metastatic breast cancer (MBC)
    • Riemsma R., Forbes C.A., Amonkar M.M., Lykopoulos K., Diaz J.R., Kleijnen J., et al. Systematic review of lapatinib in combination with letrozole compared with other first-line treatments for hormone receptor positive (HR+) and HER2+ advanced or metastatic breast cancer (MBC). Current Medical Research and Opinion 2012, 28(8):1263-1279.
    • (2012) Current Medical Research and Opinion , vol.28 , Issue.8 , pp. 1263-1279
    • Riemsma, R.1    Forbes, C.A.2    Amonkar, M.M.3    Lykopoulos, K.4    Diaz, J.R.5    Kleijnen, J.6
  • 183
    • 0023903560 scopus 로고
    • In vitro estrogenic actions in rat and human cells of hydroxylated derivatives of D16726 (zindoxifene), an agent with known antimammary cancer activity in vivo
    • Robinson S.P., Koch R., Jordan V.C. In vitro estrogenic actions in rat and human cells of hydroxylated derivatives of D16726 (zindoxifene), an agent with known antimammary cancer activity in vivo. Cancer Research 1988, 48(4):784-787.
    • (1988) Cancer Research , vol.48 , Issue.4 , pp. 784-787
    • Robinson, S.P.1    Koch, R.2    Jordan, V.C.3
  • 184
    • 85046393626 scopus 로고
    • Oestrous reactions, including mating, produced by triphenyl ethylene
    • Robson J.M. Oestrous reactions, including mating, produced by triphenyl ethylene. Nature 1937, 140(3535):196.
    • (1937) Nature , vol.140 , Issue.3535 , pp. 196
    • Robson, J.M.1
  • 185
    • 0008174249 scopus 로고
    • Duration of action of natural and synthetic oestrogens
    • Robson J.M., Schonberg A., Fahim H.A. Duration of action of natural and synthetic oestrogens. Nature 1938, 142:292-293.
    • (1938) Nature , vol.142 , pp. 292-293
    • Robson, J.M.1    Schonberg, A.2    Fahim, H.A.3
  • 186
    • 0008208018 scopus 로고
    • A new synthetic oestrogen with prolonged action when given orally
    • Robson J.M., Schonberg A. A new synthetic oestrogen with prolonged action when given orally. Nature 1942, 150(3792):22-23.
    • (1942) Nature , vol.150 , Issue.3792 , pp. 22-23
    • Robson, J.M.1    Schonberg, A.2
  • 187
    • 84858385940 scopus 로고    scopus 로고
    • Endocrine resistance in breast cancer: Molecular pathways and rational development of targeted therapies
    • Roop R.P., Ma C.X. Endocrine resistance in breast cancer: Molecular pathways and rational development of targeted therapies. Future Oncology 2012, 8(3):273-292.
    • (2012) Future Oncology , vol.8 , Issue.3 , pp. 273-292
    • Roop, R.P.1    Ma, C.X.2
  • 188
    • 0032581614 scopus 로고    scopus 로고
    • Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene
    • Rosati R.L., Da Silva Jardine P., Cameron K.O., Thompson D.D., Ke H.Z., Toler S.M., et al. Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene. Journal of Medicinal Chemistry 1998, 41(16):2928-2931.
    • (1998) Journal of Medicinal Chemistry , vol.41 , Issue.16 , pp. 2928-2931
    • Rosati, R.L.1    Da Silva Jardine, P.2    Cameron, K.O.3    Thompson, D.D.4    Ke, H.Z.5    Toler, S.M.6
  • 189
    • 0021985390 scopus 로고
    • Beneficial effect of adjuvant tamoxifen therapy in primary breast cancer patients with high oestrogen receptor values
    • Rose C., Thorpe S.M., Andersen K.W., Pedersen B.V., Mouridsen H.T., Blichert-Toft M., et al. Beneficial effect of adjuvant tamoxifen therapy in primary breast cancer patients with high oestrogen receptor values. The Lancet 1985, 1(8419):16-19.
    • (1985) The Lancet , vol.1 , Issue.8419 , pp. 16-19
    • Rose, C.1    Thorpe, S.M.2    Andersen, K.W.3    Pedersen, B.V.4    Mouridsen, H.T.5    Blichert-Toft, M.6
  • 190
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
    • Rossouw J.E., Anderson G.L., Prentice R.L., LaCroix A.Z., Kooperberg C., Stefanick M.L., et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial. Journal of the American Medical Association 2002, 288(3):321-333.
    • (2002) Journal of the American Medical Association , vol.288 , Issue.3 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3    LaCroix, A.Z.4    Kooperberg, C.5    Stefanick, M.L.6
  • 191
    • 0642367765 scopus 로고    scopus 로고
    • Effects of ospemifene, a novel SERM, on hormones, genital tract, climacteric symptoms, and quality of life in postmenopausal women: A double-blind, randomized trial
    • Rutanen E.M., Heikkinen J., Halonen K., Komi J., Lammintausta R., Ylikorkala O. Effects of ospemifene, a novel SERM, on hormones, genital tract, climacteric symptoms, and quality of life in postmenopausal women: A double-blind, randomized trial. Menopause 2003, 10(5):433-439.
    • (2003) Menopause , vol.10 , Issue.5 , pp. 433-439
    • Rutanen, E.M.1    Heikkinen, J.2    Halonen, K.3    Komi, J.4    Lammintausta, R.5    Ylikorkala, O.6
  • 192
    • 0004280071 scopus 로고
    • Fashions in cancer research
    • The Year Book Publishers, Chicago, W.B. Wartman (Ed.)
    • Schrek R. Fashions in cancer research. 1959-1960 Year book 1960, 26-39. The Year Book Publishers, Chicago. W.B. Wartman (Ed.).
    • (1960) 1959-1960 Year book , pp. 26-39
    • Schrek, R.1
  • 193
    • 70349929431 scopus 로고    scopus 로고
    • Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen
    • Schroth W., Goetz M.P., Hamann U., Fasching P.A., Schmidt M., Winter S., et al. Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen. Journal of the American Medical Association 2009, 302(13):1429-1436.
    • (2009) Journal of the American Medical Association , vol.302 , Issue.13 , pp. 1429-1436
    • Schroth, W.1    Goetz, M.P.2    Hamann, U.3    Fasching, P.A.4    Schmidt, M.5    Winter, S.6
  • 194
    • 0004496862 scopus 로고
    • Adjuvant tamoxifen in the management of operable cancer: The Scottish Trial. Report from the Breast Cancer Trials Committee, Scottish Cancer Trials Office (MRC), Edinburgh
    • SCTO
    • SCTO Adjuvant tamoxifen in the management of operable cancer: The Scottish Trial. Report from the Breast Cancer Trials Committee, Scottish Cancer Trials Office (MRC), Edinburgh. The Lancet 1987, 2(8852):171-175.
    • (1987) The Lancet , vol.2 , Issue.8852 , pp. 171-175
  • 195
    • 84880269348 scopus 로고    scopus 로고
    • Novel selective estrogen receptor modulators
    • Imperial College Press, London, V.C. Jordan (Ed.)
    • Sengupta S., Jordan V.C. Novel selective estrogen receptor modulators. Estrogen actions, SERMs, and women's health 2013, Imperial College Press, London. V.C. Jordan (Ed.).
    • (2013) Estrogen actions, SERMs, and women's health
    • Sengupta, S.1    Jordan, V.C.2
  • 196
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau A.K., Barstad D., Loria P.M., Cheng L., Kushner P.J., Agard D.A., et al. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 1998, 95(7):927-937.
    • (1998) Cell , vol.95 , Issue.7 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6
  • 197
    • 0034464912 scopus 로고    scopus 로고
    • Estradiol hypersensitivity and mitogen-activated protein kinase expression in long-term estrogen deprived human breast cancer cells in vivo
    • Shim W.S., Conaway M., Masamura S., Yue W., Wang J.P., Kmar R., et al. Estradiol hypersensitivity and mitogen-activated protein kinase expression in long-term estrogen deprived human breast cancer cells in vivo. Endocrinology 2000, 141(1):396-405.
    • (2000) Endocrinology , vol.141 , Issue.1 , pp. 396-405
    • Shim, W.S.1    Conaway, M.2    Masamura, S.3    Yue, W.4    Wang, J.P.5    Kmar, R.6
  • 198
    • 84892445320 scopus 로고
    • Effect of adrenalectomy and ovariectomy on mammary carcinogenesis in strain C3H mice
    • Shimkin M.B., Wyman R.S. Effect of adrenalectomy and ovariectomy on mammary carcinogenesis in strain C3H mice. Journal of the National Cancer Institute 1945, 6:187-189.
    • (1945) Journal of the National Cancer Institute , vol.6 , pp. 187-189
    • Shimkin, M.B.1    Wyman, R.S.2
  • 199
    • 84892443346 scopus 로고
    • Mammary tumors in male mice implanted with estrogen-cholesterol pellets
    • Shimkin M.B., Wyman R.S. Mammary tumors in male mice implanted with estrogen-cholesterol pellets. Journal of the National Cancer Institute 1946, 7(2):71-75.
    • (1946) Journal of the National Cancer Institute , vol.7 , Issue.2 , pp. 71-75
    • Shimkin, M.B.1    Wyman, R.S.2
  • 201
    • 0038386058 scopus 로고    scopus 로고
    • Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: The Women's Health Initiative Memory Study: A randomized controlled trial
    • Shumaker S.A., Legault C., Rapp S.R., Thal L., Wallace R.B., Ockene J.K., et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: The Women's Health Initiative Memory Study: A randomized controlled trial. Journal of the American Medical Association 2003, 289(20):2651-2662.
    • (2003) Journal of the American Medical Association , vol.289 , Issue.20 , pp. 2651-2662
    • Shumaker, S.A.1    Legault, C.2    Rapp, S.R.3    Thal, L.4    Wallace, R.B.5    Ockene, J.K.6
  • 202
    • 84857366519 scopus 로고    scopus 로고
    • Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: Results of a 5-year, randomized, placebo-controlled study
    • Silverman S.L., Chines A.A., Kendler D.L., Kung A.W., Teglbjaerg C.S., Felsenberg D., et al. Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: Results of a 5-year, randomized, placebo-controlled study. Osteoporosis International 2012, 23(1):351-363.
    • (2012) Osteoporosis International , vol.23 , Issue.1 , pp. 351-363
    • Silverman, S.L.1    Chines, A.A.2    Kendler, D.L.3    Kung, A.W.4    Teglbjaerg, C.S.5    Felsenberg, D.6
  • 203
    • 0035930095 scopus 로고    scopus 로고
    • Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17beta-estradiol
    • Song R.X., Mor G., Naftolin F., McPherson R.A., Song J., Zhang Z., et al. Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17beta-estradiol. Journal of the National Cancer Institute 2001, 93(22):1714-1723.
    • (2001) Journal of the National Cancer Institute , vol.93 , Issue.22 , pp. 1714-1723
    • Song, R.X.1    Mor, G.2    Naftolin, F.3    McPherson, R.A.4    Song, J.5    Zhang, Z.6
  • 206
    • 0025264960 scopus 로고
    • Phase I/II study of the anti-oestrogen zindoxifene (D16726) in the treatment of advanced breast cancer. A Cancer Research Campaign Phase I/II Clinical Trials Committee study
    • Stein R.C., Dowsett M., Cunningham D.C., Davenport J., Ford H.T., Gazet J.C., et al. Phase I/II study of the anti-oestrogen zindoxifene (D16726) in the treatment of advanced breast cancer. A Cancer Research Campaign Phase I/II Clinical Trials Committee study. British Journal of Cancer 1990, 61(3):451-453.
    • (1990) British Journal of Cancer , vol.61 , Issue.3 , pp. 451-453
    • Stein, R.C.1    Dowsett, M.2    Cunningham, D.C.3    Davenport, J.4    Ford, H.T.5    Gazet, J.C.6
  • 208
    • 0007444568 scopus 로고
    • Palliation by castration or by hormone administration
    • W. Heinemann Medical Books Ltd, London, B.A. Stoll (Ed.)
    • Stoll B.A. Palliation by castration or by hormone administration. Breast cancer management early and late 1977, 133-146. W. Heinemann Medical Books Ltd, London. B.A. Stoll (Ed.).
    • (1977) Breast cancer management early and late , pp. 133-146
    • Stoll, B.A.1
  • 213
    • 0013913886 scopus 로고
    • A receptor molecule for estrogens: Isolation from the rat uterus and preliminary characterization
    • Toft D., Gorski J. A receptor molecule for estrogens: Isolation from the rat uterus and preliminary characterization. PNAS 1966, 55(6):1574-1581.
    • (1966) PNAS , vol.55 , Issue.6 , pp. 1574-1581
    • Toft, D.1    Gorski, J.2
  • 215
    • 0031788304 scopus 로고    scopus 로고
    • Differential responses of estrogen target tissues in rats including bone to clomiphene, enclomiphene, and zuclomiphene
    • Turner R.T., Evans G.L., Sluka J.P., Adrian M.D., Bryant H.U., Turner C.H., et al. Differential responses of estrogen target tissues in rats including bone to clomiphene, enclomiphene, and zuclomiphene. Endocrinology 1998, 139(9):3712-3720.
    • (1998) Endocrinology , vol.139 , Issue.9 , pp. 3712-3720
    • Turner, R.T.1    Evans, G.L.2    Sluka, J.P.3    Adrian, M.D.4    Bryant, H.U.5    Turner, C.H.6
  • 216
    • 0027400961 scopus 로고
    • Mechanism of action of estrogen on cancellous bone balance in tibiae of ovariectomized growing rats: Inhibition of indices of formation and resorption
    • Turner R.T., Evans G.L., Wakley G.K. Mechanism of action of estrogen on cancellous bone balance in tibiae of ovariectomized growing rats: Inhibition of indices of formation and resorption. Journal of Bone and Mineral Research 1993, 8(3):359-366.
    • (1993) Journal of Bone and Mineral Research , vol.8 , Issue.3 , pp. 359-366
    • Turner, R.T.1    Evans, G.L.2    Wakley, G.K.3
  • 218
    • 0023930991 scopus 로고
    • Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats
    • Turner R.T., Wakley G.K., Hannon K.S., Bell N.H. Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats. Endocrinology 1988, 122(3):1146-1150.
    • (1988) Endocrinology , vol.122 , Issue.3 , pp. 1146-1150
    • Turner, R.T.1    Wakley, G.K.2    Hannon, K.S.3    Bell, N.H.4
  • 219
    • 0032508293 scopus 로고    scopus 로고
    • Prevention of breast cancer with tamoxifen: Preliminary findings from the Italian randomised trial among hysterectomised women. Italian Tamoxifen Prevention Study
    • Veronesi U., Maisonneuve P., Costa A., Sacchini V., Maltoni C., Robertson C., et al. Prevention of breast cancer with tamoxifen: Preliminary findings from the Italian randomised trial among hysterectomised women. Italian Tamoxifen Prevention Study. The Lancet 1998, 352(9122):93-97.
    • (1998) The Lancet , vol.352 , Issue.9122 , pp. 93-97
    • Veronesi, U.1    Maisonneuve, P.2    Costa, A.3    Sacchini, V.4    Maltoni, C.5    Robertson, C.6
  • 220
    • 33745249570 scopus 로고    scopus 로고
    • Effects of tamoxifen vs. raloxifene on the risk of developing invasive breast cancer and other disease outcomes: The NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial
    • Vogel V.G., Costantino J.P., Wickerham D.L., Cronin W.M., Cecchini R.S., Atkins J.N., et al. Effects of tamoxifen vs. raloxifene on the risk of developing invasive breast cancer and other disease outcomes: The NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. Journal of the American Medical Association 2006, 295(23):2727-2741.
    • (2006) Journal of the American Medical Association , vol.295 , Issue.23 , pp. 2727-2741
    • Vogel, V.G.1    Costantino, J.P.2    Wickerham, D.L.3    Cronin, W.M.4    Cecchini, R.S.5    Atkins, J.N.6
  • 221
  • 222
    • 0037145885 scopus 로고    scopus 로고
    • Effects of ospemifene (FC-1271a) on uterine endometrium, vaginal maturation index, and hormonal status in healthy postmenopausal women
    • Voipio S.K., Komi J., Kangas L., Halonen K., DeGregorio M.W., Erkkola R.U. Effects of ospemifene (FC-1271a) on uterine endometrium, vaginal maturation index, and hormonal status in healthy postmenopausal women. Maturitas 2002, 43(3):207-214.
    • (2002) Maturitas , vol.43 , Issue.3 , pp. 207-214
    • Voipio, S.K.1    Komi, J.2    Kangas, L.3    Halonen, K.4    DeGregorio, M.W.5    Erkkola, R.U.6
  • 224
    • 0001528477 scopus 로고
    • Synthetic oestrogens in mammary cancer
    • Walpole A.L., Paterson E. Synthetic oestrogens in mammary cancer. The Lancet 1949, 2(6583):783-786.
    • (1949) The Lancet , vol.2 , Issue.6583 , pp. 783-786
    • Walpole, A.L.1    Paterson, E.2
  • 225
    • 0141455199 scopus 로고    scopus 로고
    • Discovery and preclinical characterization of (+)-3-[4-(1-piperidinoethoxy)phenyl]spiro[indene-1,1'-indane]-5,5'-diol hydrochloride: A promising nonsteroidal estrogen receptor agonist for hot flush
    • Watanabe N., Ikeno A., Minato H., Nakagawa H., Kohayakawa C., Tsuji J. Discovery and preclinical characterization of (+)-3-[4-(1-piperidinoethoxy)phenyl]spiro[indene-1,1'-indane]-5,5'-diol hydrochloride: A promising nonsteroidal estrogen receptor agonist for hot flush. Journal of Medicinal Chemistry 2003, 46(19):3961-3964.
    • (2003) Journal of Medicinal Chemistry , vol.46 , Issue.19 , pp. 3961-3964
    • Watanabe, N.1    Ikeno, A.2    Minato, H.3    Nakagawa, H.4    Kohayakawa, C.5    Tsuji, J.6
  • 226
    • 0022004418 scopus 로고
    • Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: A review and tribute to Charles Brenton Huggins
    • Welsch C.W. Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: A review and tribute to Charles Brenton Huggins. Cancer Research 1985, 45(8):3415-3443.
    • (1985) Cancer Research , vol.45 , Issue.8 , pp. 3415-3443
    • Welsch, C.W.1
  • 227
    • 0023606475 scopus 로고
    • Adaptation of estrogen-dependent MCF-7 cells to low estrogen (phenol red-free) culture
    • Welshons W.V., Jordan V.C. Adaptation of estrogen-dependent MCF-7 cells to low estrogen (phenol red-free) culture. European Journal of Cancer & Clinical Oncology 1987, 23(12):1935-1939.
    • (1987) European Journal of Cancer & Clinical Oncology , vol.23 , Issue.12 , pp. 1935-1939
    • Welshons, W.V.1    Jordan, V.C.2
  • 228
    • 0027357258 scopus 로고
    • A laboratory model to explain the survival advantage observed in patients taking adjuvant tamoxifen therapy
    • Wolf D.M., Jordan V.C. A laboratory model to explain the survival advantage observed in patients taking adjuvant tamoxifen therapy. Recent Results in Cancer Research 1993, 127:23-33.
    • (1993) Recent Results in Cancer Research , vol.127 , pp. 23-33
    • Wolf, D.M.1    Jordan, V.C.2
  • 230
    • 0034066141 scopus 로고    scopus 로고
    • Antitumor action of physiological estradiol on tamoxifen-stimulated breast tumors grown in athymic mice
    • Yao K., Lee E.S., Bentrem D.J., England G., Schafer J.I., O'Regan R.M., et al. Antitumor action of physiological estradiol on tamoxifen-stimulated breast tumors grown in athymic mice. Clinical Cancer Research 2000, 6(5):2028-2036.
    • (2000) Clinical Cancer Research , vol.6 , Issue.5 , pp. 2028-2036
    • Yao, K.1    Lee, E.S.2    Bentrem, D.J.3    England, G.4    Schafer, J.I.5    O'Regan, R.M.6


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