메뉴 건너뛰기




Volumn 10, Issue 1-2, 2013, Pages

Non-alcoholic fatty liver disease: More than just ectopic fat accumulation

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; C REACTIVE PROTEIN; CARBOHYDRATE; LEPTIN; LIPID; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNCOUPLING PROTEIN 2; VERY LOW DENSITY LIPOPROTEIN;

EID: 84880217848     PISSN: None     EISSN: 17406765     Source Type: Journal    
DOI: 10.1016/j.ddmec.2013.06.002     Document Type: Review
Times cited : (6)

References (75)
  • 1
    • 80052236883 scopus 로고    scopus 로고
    • The global obesity pandemic: Shaped by global drivers and local environments
    • B.A. Swinburn The global obesity pandemic: shaped by global drivers and local environments Lancet 378 2011 804 814
    • (2011) Lancet , vol.378 , pp. 804-814
    • Swinburn, B.A.1
  • 2
    • 25844500757 scopus 로고    scopus 로고
    • Predictors of nonalcoholic steatohepatitis (NASH) in obese patients undergoing gastric bypass
    • C. Boza Predictors of nonalcoholic steatohepatitis (NASH) in obese patients undergoing gastric bypass Obes. Surg. 15 2005 1148 1153
    • (2005) Obes. Surg. , vol.15 , pp. 1148-1153
    • Boza, C.1
  • 3
    • 78649438520 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Liver disease: An overlooked complication of diabetes mellitus
    • M. Arrese Nonalcoholic fatty liver disease: liver disease: an overlooked complication of diabetes mellitus Nat. Rev. Endocrinol. 6 2010 660 661
    • (2010) Nat. Rev. Endocrinol. , vol.6 , pp. 660-661
    • Arrese, M.1
  • 4
    • 75449102165 scopus 로고    scopus 로고
    • Long-term mortality in nonalcoholic fatty liver disease: Is liver histology of any prognostic significance
    • P. Angulo Long-term mortality in nonalcoholic fatty liver disease: is liver histology of any prognostic significance Hepatology 51 2010 373 375
    • (2010) Hepatology , vol.51 , pp. 373-375
    • Angulo, P.1
  • 5
    • 0037382786 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
    • G. Marchesini Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome Hepatology 37 2003 917 923
    • (2003) Hepatology , vol.37 , pp. 917-923
    • Marchesini, G.1
  • 6
    • 33750606061 scopus 로고    scopus 로고
    • Long-term follow-up of patients with NAFLD and elevated liver enzymes
    • M. Ekstedt Long-term follow-up of patients with NAFLD and elevated liver enzymes Hepatology 44 2006 865 873
    • (2006) Hepatology , vol.44 , pp. 865-873
    • Ekstedt, M.1
  • 7
    • 11144351102 scopus 로고    scopus 로고
    • The histological course of nonalcoholic fatty liver disease: A longitudinal study of 103 patients with sequential liver biopsies
    • L.A. Adams The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies J. Hepatol. 42 2005 132 138
    • (2005) J. Hepatol. , vol.42 , pp. 132-138
    • Adams, L.A.1
  • 8
    • 34247384560 scopus 로고    scopus 로고
    • The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD
    • P. Angulo The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD Hepatology 45 2007 846 854
    • (2007) Hepatology , vol.45 , pp. 846-854
    • Angulo, P.1
  • 9
    • 22344452893 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease: A population-based cohort study
    • L.A. Adams The natural history of nonalcoholic fatty liver disease: a population-based cohort study Gastroenterology 129 2005 113 121
    • (2005) Gastroenterology , vol.129 , pp. 113-121
    • Adams, L.A.1
  • 10
    • 79959517565 scopus 로고    scopus 로고
    • Human fatty liver disease: Old questions and new insights
    • J.C. Cohen Human fatty liver disease: old questions and new insights Science 332 2011 1519 1523
    • (2011) Science , vol.332 , pp. 1519-1523
    • Cohen, J.C.1
  • 11
    • 70349238777 scopus 로고    scopus 로고
    • Adipokines in liver diseases
    • F. Marra, and C. Bertolani Adipokines in liver diseases Hepatology 50 2009 957 969
    • (2009) Hepatology , vol.50 , pp. 957-969
    • Marra, F.1    Bertolani, C.2
  • 12
    • 79151484704 scopus 로고    scopus 로고
    • Adipokines in inflammation and metabolic disease
    • N. Ouchi Adipokines in inflammation and metabolic disease Nat. Rev. Immunol. 11 2011 85 97
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 85-97
    • Ouchi, N.1
  • 13
    • 66449137379 scopus 로고    scopus 로고
    • GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
    • H.L. Kammoun GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice J. Clin. Invest. 119 2009 1201 1215
    • (2009) J. Clin. Invest. , vol.119 , pp. 1201-1215
    • Kammoun, H.L.1
  • 14
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • K.L. Donnelly Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease J. Clin. Invest. 115 2005 1343 1351
    • (2005) J. Clin. Invest. , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1
  • 15
    • 77957838795 scopus 로고    scopus 로고
    • Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
    • A. Kosteli Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue J. Clin. Invest. 120 2010 3466 3479
    • (2010) J. Clin. Invest. , vol.120 , pp. 3466-3479
    • Kosteli, A.1
  • 16
    • 33847073149 scopus 로고    scopus 로고
    • Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
    • C.N. Lumeng Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity Diabetes 56 2007 16 23
    • (2007) Diabetes , vol.56 , pp. 16-23
    • Lumeng, C.N.1
  • 17
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: Common threads and missing links
    • V.T. Samuel, and G.I. Shulman Mechanisms for insulin resistance: common threads and missing links Cell 148 2012 852 871
    • (2012) Cell , vol.148 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 18
    • 58149347227 scopus 로고    scopus 로고
    • Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
    • C.N. Lumeng Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes Diabetes 57 2008 3239 3246
    • (2008) Diabetes , vol.57 , pp. 3239-3246
    • Lumeng, C.N.1
  • 19
    • 84856533216 scopus 로고    scopus 로고
    • Increased macrophage migration into adipose tissue in obese mice
    • D.Y. Oh Increased macrophage migration into adipose tissue in obese mice Diabetes 61 2012 346 354
    • (2012) Diabetes , vol.61 , pp. 346-354
    • Oh, D.Y.1
  • 20
    • 79957920754 scopus 로고    scopus 로고
    • Inflammatory links between obesity and metabolic disease
    • C.N. Lumeng, and A.R. Saltiel Inflammatory links between obesity and metabolic disease J. Clin. Invest. 121 2011 2111 2117
    • (2011) J. Clin. Invest. , vol.121 , pp. 2111-2117
    • Lumeng, C.N.1    Saltiel, A.R.2
  • 21
    • 84863508993 scopus 로고    scopus 로고
    • Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling
    • K. Imajo Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling Cell Metab. 16 2012 44 54
    • (2012) Cell Metab. , vol.16 , pp. 44-54
    • Imajo, K.1
  • 22
    • 67349205002 scopus 로고    scopus 로고
    • Kupffer cells in non-alcoholic fatty liver disease: The emerging view
    • G. Baffy Kupffer cells in non-alcoholic fatty liver disease: the emerging view J. Hepatol. 51 2009 212 223
    • (2009) J. Hepatol. , vol.51 , pp. 212-223
    • Baffy, G.1
  • 23
    • 34250356015 scopus 로고    scopus 로고
    • Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
    • K. Yamaguchi Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis Hepatology 45 2007 1366 1374
    • (2007) Hepatology , vol.45 , pp. 1366-1374
    • Yamaguchi, K.1
  • 24
    • 84860326669 scopus 로고    scopus 로고
    • NASH is an inflammatory disorder: Pathogenic, prognostic and therapeutic implications
    • G.C. Farrell NASH is an inflammatory disorder: pathogenic, prognostic and therapeutic implications Gut Liver 6 2012 149 171
    • (2012) Gut Liver , vol.6 , pp. 149-171
    • Farrell, G.C.1
  • 25
    • 78650615554 scopus 로고    scopus 로고
    • Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity
    • S.W. Park Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity Proc. Natl. Acad. Sci. U. S. A. 107 2010 19320 19325
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 19320-19325
    • Park, S.W.1
  • 26
    • 82955239838 scopus 로고    scopus 로고
    • Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease
    • N.E. Sunny Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease Cell Metab. 14 2011 804 810
    • (2011) Cell Metab. , vol.14 , pp. 804-810
    • Sunny, N.E.1
  • 27
    • 79960555502 scopus 로고    scopus 로고
    • Metabolic factors in the development of hepatic steatosis and altered mitochondrial gene expression in vivo
    • S. Wang Metabolic factors in the development of hepatic steatosis and altered mitochondrial gene expression in vivo Metabolism 60 2011 1090 1099
    • (2011) Metabolism , vol.60 , pp. 1090-1099
    • Wang, S.1
  • 28
    • 84861451144 scopus 로고    scopus 로고
    • Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver
    • S. Satapati Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver J. Lipid Res. 53 2012 1080 1092
    • (2012) J. Lipid Res. , vol.53 , pp. 1080-1092
    • Satapati, S.1
  • 29
    • 46349087273 scopus 로고    scopus 로고
    • Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury
    • G. Serviddio Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury Gut 57 2008 957 965
    • (2008) Gut , vol.57 , pp. 957-965
    • Serviddio, G.1
  • 30
    • 33845938010 scopus 로고    scopus 로고
    • Hepatic histopathology of morbid obesity: Concurrence of other forms of chronic liver disease
    • P.L. Liew Hepatic histopathology of morbid obesity: concurrence of other forms of chronic liver disease Obes. Surg. 16 2006 1584 1593
    • (2006) Obes. Surg. , vol.16 , pp. 1584-1593
    • Liew, P.L.1
  • 31
    • 84856957894 scopus 로고    scopus 로고
    • Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
    • J. Henao-Mejia Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity Nature 482 2012 179 185
    • (2012) Nature , vol.482 , pp. 179-185
    • Henao-Mejia, J.1
  • 32
    • 84859164281 scopus 로고    scopus 로고
    • Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation
    • C.L. Roth Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation Hepatology 55 2012 1103 1111
    • (2012) Hepatology , vol.55 , pp. 1103-1111
    • Roth, C.L.1
  • 33
    • 84863663452 scopus 로고    scopus 로고
    • Calcium and vitamin D in obesity
    • Q. Song, and I.N. Sergeev Calcium and vitamin D in obesity Nutr. Res. Rev. 25 2012 130 141
    • (2012) Nutr. Res. Rev. , vol.25 , pp. 130-141
    • Song, Q.1    Sergeev, I.N.2
  • 34
    • 65249188812 scopus 로고    scopus 로고
    • Heritability of nonalcoholic fatty liver disease
    • J.B. Schwimmer Heritability of nonalcoholic fatty liver disease Gastroenterology 136 2009 1585 1592
    • (2009) Gastroenterology , vol.136 , pp. 1585-1592
    • Schwimmer, J.B.1
  • 35
    • 56749096610 scopus 로고    scopus 로고
    • Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
    • S. Romeo Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease Nat. Genet. 40 2008 1461 1465
    • (2008) Nat. Genet. , vol.40 , pp. 1461-1465
    • Romeo, S.1
  • 36
    • 77956636268 scopus 로고    scopus 로고
    • The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease
    • Y. Rotman The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease Hepatology 52 2010 894 903
    • (2010) Hepatology , vol.52 , pp. 894-903
    • Rotman, Y.1
  • 37
    • 84881559322 scopus 로고    scopus 로고
    • PNPLA3 I148M variant and hepatocellular carcinoma: A common genetic variant for a rare disease
    • 10.1016/j.dld.2012.12.006 [Epub ahead of print]
    • L. Valenti PNPLA3 I148M variant and hepatocellular carcinoma: a common genetic variant for a rare disease Dig. Liver Dis. 2013 10.1016/j.dld.2012.12. 006 [Epub ahead of print]
    • (2013) Dig. Liver Dis.
    • Valenti, L.1
  • 38
    • 79957462315 scopus 로고    scopus 로고
    • Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
    • S. Sookoian, and C.J. Pirola Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease Hepatology 53 2011 1883 1894
    • (2011) Hepatology , vol.53 , pp. 1883-1894
    • Sookoian, S.1    Pirola, C.J.2
  • 39
    • 84860465005 scopus 로고    scopus 로고
    • Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase
    • M. Kumari Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase Cell Metab. 15 2012 691 702
    • (2012) Cell Metab. , vol.15 , pp. 691-702
    • Kumari, M.1
  • 40
    • 77950202777 scopus 로고    scopus 로고
    • Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease
    • K.F. Petersen Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease N. Engl. J. Med. 362 2010 1082 1089
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1082-1089
    • Petersen, K.F.1
  • 41
    • 79953745343 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits
    • E.K. Speliotes Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits PLoS Genet. 7 2011 e1001324
    • (2011) PLoS Genet. , vol.7 , pp. 1001324
    • Speliotes, E.K.1
  • 42
    • 78049457761 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants associated with histologic features of nonalcoholic fatty liver disease
    • 1576 e1561-1566
    • N. Chalasani Genome-wide association study identifies variants associated with histologic features of nonalcoholic fatty liver disease Gastroenterology 139 2010 1567 1576 1576 e1561-1566
    • (2010) Gastroenterology , vol.139 , pp. 1567-1576
    • Chalasani, N.1
  • 43
    • 79251523832 scopus 로고    scopus 로고
    • Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance
    • J. Kozlitina Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance Hepatology 53 2011 467 474
    • (2011) Hepatology , vol.53 , pp. 467-474
    • Kozlitina, J.1
  • 44
    • 84873312029 scopus 로고    scopus 로고
    • Association between liver-specific gene polymorphisms and their expression levels with nonalcoholic fatty liver disease
    • L.A. Adams Association between liver-specific gene polymorphisms and their expression levels with nonalcoholic fatty liver disease Hepatology 57 2013 590 600
    • (2013) Hepatology , vol.57 , pp. 590-600
    • Adams, L.A.1
  • 45
    • 79953321200 scopus 로고    scopus 로고
    • Genetic determinants of hepatic steatosis in man
    • A.J. Hooper Genetic determinants of hepatic steatosis in man J. Lipid Res. 52 2011 593 617
    • (2011) J. Lipid Res. , vol.52 , pp. 593-617
    • Hooper, A.J.1
  • 46
    • 84870268640 scopus 로고    scopus 로고
    • Multigenerational epigenetic adaptation of the hepatic wound-healing response
    • M. Zeybel Multigenerational epigenetic adaptation of the hepatic wound-healing response Nat. Med. 18 2012 1592
    • (2012) Nat. Med. , vol.18 , pp. 1592
    • Zeybel, M.1
  • 47
    • 84879602668 scopus 로고    scopus 로고
    • Maternal obesity programs offspring non-alcoholic fatty liver disease via innate immune dysfunction in mice
    • 10.1002/hep.26248 [Epub ahead of print]
    • A. Mouralidarane Maternal obesity programs offspring non-alcoholic fatty liver disease via innate immune dysfunction in mice Hepatology 2013 10.1002/hep.26248 [Epub ahead of print]
    • (2013) Hepatology
    • Mouralidarane, A.1
  • 48
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • J.P. Despres, and I. Lemieux Abdominal obesity and metabolic syndrome Nature 444 2006 881 887
    • (2006) Nature , vol.444 , pp. 881-887
    • Despres, J.P.1    Lemieux, I.2
  • 49
    • 75449094816 scopus 로고    scopus 로고
    • Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications
    • E. Fabbrini Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications Hepatology 51 2010 679 689
    • (2010) Hepatology , vol.51 , pp. 679-689
    • Fabbrini, E.1
  • 50
    • 70349326750 scopus 로고    scopus 로고
    • Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
    • E. Fabbrini Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity Proc. Natl. Acad. Sci. U. S. A. 106 2009 15430 15435
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 15430-15435
    • Fabbrini, E.1
  • 51
    • 84860497397 scopus 로고    scopus 로고
    • Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance
    • F.R. Jornayvaz, and G.I. Shulman Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance Cell Metab. 15 2012 574 584
    • (2012) Cell Metab. , vol.15 , pp. 574-584
    • Jornayvaz, F.R.1    Shulman, G.I.2
  • 52
    • 79955487247 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice
    • W.L. Holland Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice J. Clin. Invest. 121 2011 1858 1870
    • (2011) J. Clin. Invest. , vol.121 , pp. 1858-1870
    • Holland, W.L.1
  • 54
    • 34347235098 scopus 로고    scopus 로고
    • Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
    • M. Monetti Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver Cell Metab. 6 2007 69 78
    • (2007) Cell Metab. , vol.6 , pp. 69-78
    • Monetti, M.1
  • 55
    • 84864710223 scopus 로고    scopus 로고
    • Selective insulin and leptin resistance in metabolic disorders
    • A.C. Konner, and J.C. Bruning Selective insulin and leptin resistance in metabolic disorders Cell Metab. 16 2012 144 152
    • (2012) Cell Metab. , vol.16 , pp. 144-152
    • Konner, A.C.1    Bruning, J.C.2
  • 56
    • 77957375969 scopus 로고    scopus 로고
    • Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease
    • G. Targher Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease N. Engl. J. Med. 363 2010 1341 1350
    • (2010) N. Engl. J. Med. , vol.363 , pp. 1341-1350
    • Targher, G.1
  • 57
    • 84864360646 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is associated with coronary artery calcification
    • D. Kim Nonalcoholic fatty liver disease is associated with coronary artery calcification Hepatology 56 2012 605 613
    • (2012) Hepatology , vol.56 , pp. 605-613
    • Kim, D.1
  • 58
    • 84866561339 scopus 로고    scopus 로고
    • Fatty liver, abdominal adipose tissue and atherosclerotic calcification in African Americans: The Jackson Heart Study
    • J. Liu Fatty liver, abdominal adipose tissue and atherosclerotic calcification in African Americans: the Jackson Heart Study Atherosclerosis 224 2012 521 525
    • (2012) Atherosclerosis , vol.224 , pp. 521-525
    • Liu, J.1
  • 59
    • 51949114908 scopus 로고    scopus 로고
    • Association between non-subcutaneous adiposity and calcified coronary plaque: A substudy of the multi-ethnic study of atherosclerosis
    • J. Ding Association between non-subcutaneous adiposity and calcified coronary plaque: a substudy of the multi-ethnic study of atherosclerosis Am. J. Clin. Nutr. 88 2008 645 650
    • (2008) Am. J. Clin. Nutr. , vol.88 , pp. 645-650
    • Ding, J.1
  • 60
    • 34247636128 scopus 로고    scopus 로고
    • Differences and similarities in early atherosclerosis between patients with non-alcoholic steatohepatitis and chronic hepatitis B and C
    • G. Targher Differences and similarities in early atherosclerosis between patients with non-alcoholic steatohepatitis and chronic hepatitis B and C J. Hepatol. 46 2007 1126 1132
    • (2007) J. Hepatol. , vol.46 , pp. 1126-1132
    • Targher, G.1
  • 61
    • 79959548471 scopus 로고    scopus 로고
    • Mortality in nonalcoholic fatty liver disease: Clues from the Cremona study
    • L.A. Adams Mortality in nonalcoholic fatty liver disease: clues from the Cremona study Hepatology 54 2011 6 8
    • (2011) Hepatology , vol.54 , pp. 6-8
    • Adams, L.A.1
  • 62
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults
    • E.E. Calle Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults N. Engl. J. Med. 348 2003 1625 1638
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1625-1638
    • Calle, E.E.1
  • 63
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection
    • B.Q. Starley Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection Hepatology 51 2010 1820 1832
    • (2010) Hepatology , vol.51 , pp. 1820-1832
    • Starley, B.Q.1
  • 64
    • 84865512531 scopus 로고    scopus 로고
    • Excess body weight and the risk of primary liver cancer: An updated meta-analysis of prospective studies
    • Y. Chen Excess body weight and the risk of primary liver cancer: an updated meta-analysis of prospective studies Eur. J. Cancer 48 2012 2137 2145
    • (2012) Eur. J. Cancer , vol.48 , pp. 2137-2145
    • Chen, Y.1
  • 65
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • R. Zoncu mTOR: from growth signal integration to cancer, diabetes and ageing Nat. Rev. Mol. Cell Biol. 12 2011 21 35
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 21-35
    • Zoncu, R.1
  • 66
    • 84859978328 scopus 로고    scopus 로고
    • V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis
    • M. Evert V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis Hepatology 55 2012 1473 1484
    • (2012) Hepatology , vol.55 , pp. 1473-1484
    • Evert, M.1
  • 67
    • 78049478003 scopus 로고    scopus 로고
    • Adiponectin modulates C-jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma
    • 1773 e1761-1765
    • N.K. Saxena Adiponectin modulates C-jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma Gastroenterology 139 2010 1762 1773 1773 e1761-1765
    • (2010) Gastroenterology , vol.139 , pp. 1762-1773
    • Saxena, N.K.1
  • 68
    • 78049525062 scopus 로고    scopus 로고
    • Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis
    • D. Sharma Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis Hepatology 52 2010 1713 1722
    • (2010) Hepatology , vol.52 , pp. 1713-1722
    • Sharma, D.1
  • 69
    • 79955804203 scopus 로고    scopus 로고
    • High prevalence of colorectal neoplasm in patients with non-alcoholic steatohepatitis
    • V.W. Wong High prevalence of colorectal neoplasm in patients with non-alcoholic steatohepatitis Gut 60 2011 829 836
    • (2011) Gut , vol.60 , pp. 829-836
    • Wong, V.W.1
  • 70
    • 36248987256 scopus 로고    scopus 로고
    • A case-control study of non-alcoholic fatty liver disease in breast cancer
    • A. Bilici A case-control study of non-alcoholic fatty liver disease in breast cancer Med. Oncol. 24 2007 367 371
    • (2007) Med. Oncol. , vol.24 , pp. 367-371
    • Bilici, A.1
  • 71
    • 79955441997 scopus 로고    scopus 로고
    • Metabolic surgery and cancer: Protective effects of bariatric procedures
    • H. Ashrafian Metabolic surgery and cancer: protective effects of bariatric procedures Cancer 117 2011 1788 1799
    • (2011) Cancer , vol.117 , pp. 1788-1799
    • Ashrafian, H.1
  • 72
    • 84870395841 scopus 로고    scopus 로고
    • Bariatric surgery and cardiovascular outcomes: A systematic review
    • A.R. Vest Bariatric surgery and cardiovascular outcomes: a systematic review Heart 98 2012 1763 1777
    • (2012) Heart , vol.98 , pp. 1763-1777
    • Vest, A.R.1
  • 73
    • 84865293878 scopus 로고    scopus 로고
    • Bariatric surgery and prevention of type 2 diabetes in Swedish obese subjects
    • L.M. Carlsson Bariatric surgery and prevention of type 2 diabetes in Swedish obese subjects N. Engl. J. Med. 367 2012 695 704
    • (2012) N. Engl. J. Med. , vol.367 , pp. 695-704
    • Carlsson, L.M.1
  • 74
    • 84859419232 scopus 로고    scopus 로고
    • Bariatric surgery versus conventional medical therapy for type 2 diabetes
    • G. Mingrone Bariatric surgery versus conventional medical therapy for type 2 diabetes N. Engl. J. Med. 366 2012 1577 1585
    • (2012) N. Engl. J. Med. , vol.366 , pp. 1577-1585
    • Mingrone, G.1
  • 75
    • 84860136615 scopus 로고    scopus 로고
    • Bariatric surgery versus intensive medical therapy in obese patients with diabetes
    • P.R. Schauer Bariatric surgery versus intensive medical therapy in obese patients with diabetes N. Engl. J. Med. 366 2012 1567 1576
    • (2012) N. Engl. J. Med. , vol.366 , pp. 1567-1576
    • Schauer, P.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.