Investigation of the inhibitory effects of the benzodiazepine derivative, 5-BDBD on P2X 4 purinergic receptors by two complementary methods

Cellular Physiology and Biochemistry

Volumn 32, Issue 1, 2013, Pages 11-24

  Balázs, Bernadett ^a   Dankó, Tamás ^a   Kovács, Gergely ^b   Köles, László ^a   Hediger, Matthias A ^b   Zsembery, Ákos ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

5 BDBD; ATP; Calcium infux; Electrophysiology; P2X receptors

Indexed keywords

ADENOSINE TRIPHOSPHATE; BENZODIAZEPINE DERIVATIVE; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2Y RECEPTOR; CALCIUM ION; CELL SURFACE PROTEIN;

ANALYTIC METHOD; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ION CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STIMULATION; WHOLE CELL; AMINO ACID SEQUENCE; CALCIUM TRANSPORT; CELL DENSITY; CELL SURFACE; CELL SURVIVAL; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; FLUORESCENCE MICROSCOPY; IC50; IN VITRO STUDY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; BENZODIAZEPINES; BENZODIAZEPINONES; CALCIUM; CALCIUM SIGNALING; HEK293 CELLS; HUMANS; PATCH-CLAMP TECHNIQUES; PURINERGIC P2X RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2X4; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 84880182215     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000350119     Document Type: Article

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