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Volumn 7, Issue 2, 2013, Pages 122-133

Solubilization of poorly water-soluble drugs using solid dispersions

Author keywords

Characterization method; Poorly water soluble drugs; Preparation method; Solid dispersion; Solubilization

Indexed keywords

CANDESARTAN HEXETIL; CARBAMAZEPINE; CYCLODEXTRIN; DANAZOL; EBASTINE; FENOFIBRATE; GRISEOFULVIN; ITRACONAZOLE; POLOXAMER; ROTIGOTINE; SILYMARIN; TACROLIMUS;

EID: 84880161925     PISSN: 18722113     EISSN: None     Source Type: Journal    
DOI: 10.2174/1872211311307020004     Document Type: Review
Times cited : (18)

References (90)
  • 3
    • 84880143133 scopus 로고    scopus 로고
    • United States Pharmacopoeia (USP30/NF 25)
    • United States Pharmacopoeia (USP30/NF 25).
  • 8
    • 0034601240 scopus 로고    scopus 로고
    • Improving drug solubility for oral delivery using solid dispersions
    • Leuner C, Dressman J. Improving drug solubility for oral delivery using solid dispersions. Eur. J. Pharm. Biopharm. 2000; 50: 47-60.
    • (2000) Eur. J. Pharm. Biopharm , vol.50 , pp. 47-60
    • Leuner, C.1    Dressman, J.2
  • 18
    • 0029819323 scopus 로고    scopus 로고
    • Pharmaceutical Applications of Cyclodextrins. 1. Drug Solubilization and Stabilization
    • Loftsson, T., Brewster M.E. Pharmaceutical Applications of Cyclodextrins. 1. Drug Solubilization and Stabilization. J. Pharm. Sci. 1996; 85: 1027-1025.
    • (1996) J. Pharm. Sci , vol.85 , pp. 1027-1125
    • Loftsson, T.1    Brewster, M.E.2
  • 35
    • 0343920799 scopus 로고    scopus 로고
    • Methods of studying aging and stabilization of spray-congealed solid dispersions with carnauba wax. 1. Microcalorimetric investigation
    • Emås M, Nyqvist, H. Methods of studying aging and stabilization of spray-congealed solid dispersions with carnauba wax. 1. Microcalorimetric investigation, Int J Pharm 2000; 197: 117-27.
    • (2000) Int J Pharm , vol.197 , pp. 117-127
    • Emås, M.1    Nyqvist, H.2
  • 36
    • 74049128678 scopus 로고    scopus 로고
    • Solid lipid microparticles produced by spray congealing: Influence of the atomizer on microparticle characteristics and mathematical modeling of the drug release
    • Passerini, N., Qi, S., Albertini, B., Grassi, M., Rodriguez, L., Craig, D.Q.M. Solid lipid microparticles produced by spray congealing: Influence of the atomizer on microparticle characteristics and mathematical modeling of the drug release. J Pharmaceut Sci 2010, 99: 916-31.
    • (2010) J Pharmaceut Sci , vol.99 , pp. 916-931
    • Passerini, N.1    Qi, S.2    Albertini, B.3    Grassi, M.4    Rodriguez, L.5    Craig, D.Q.M.6
  • 37
    • 68249111579 scopus 로고    scopus 로고
    • Evaluation of spray congealing as technique for the preparation of highly loaded solid lipid microparticles containing the sunscreen agent, avobenzone
    • Albertini, B., Mezzena, M., Passerini, N., Rodriguez, L., Scalia, S. Evaluation of spray congealing as technique for the preparation of highly loaded solid lipid microparticles containing the sunscreen agent, avobenzone. J Pharmaceut Sci 2009; 98: 2759-69.
    • (2009) J Pharmaceut Sci , vol.98 , pp. 2759-2769
    • Albertini, B.1    Mezzena, M.2    Passerini, N.3    Rodriguez, L.4    Scalia, S.5
  • 38
    • 0037168219 scopus 로고    scopus 로고
    • Ultrasound-compacted and spray-congealed indomethacin/polyethyleneglycol systems
    • Fini A, Rodriguez L, Cavallari C, Albertini B, Passerini N. Ultrasound-compacted and spray-congealed indomethacin/polyethyleneglycol systems. Int J Pharm 2002, 247: 11-22.
    • (2002) Int J Pharm , vol.247 , pp. 11-22
    • Fini, A.1    Rodriguez, L.2    Cavallari, C.3    Albertini, B.4    Passerini, N.5
  • 39
    • 33745481304 scopus 로고    scopus 로고
    • Evaluation of melt granulation and ultrasonic spray congealing as techniques to enhance the dissolution of praziquantel
    • Passerini, N., Albertini, B., Perissutti, B., Rodriguez, L. Evaluation of melt granulation and ultrasonic spray congealing as techniques to enhance the dissolution of praziquantel. Int J Pharm 2006; 318: 92-102.
    • (2006) Int J Pharm , vol.318 , pp. 92-102
    • Passerini, N.1    Albertini, B.2    Perissutti, B.3    Rodriguez, L.4
  • 55
    • 59149106998 scopus 로고    scopus 로고
    • Piroxicam/2hydroxypropyl-cyclodextrin inclusion complex prepared by a new fluid-bed coating technique
    • Zhang, X., Wu, D., Lai, J., Lu, Y., Yin, Z., Wu, W. Piroxicam/2hydroxypropyl-cyclodextrin inclusion complex prepared by a new fluid-bed coating technique. J Pharmaceut Sci, 2009, 98: 665-675.
    • (2009) J Pharmaceut Sci , vol.98 , pp. 665-675
    • Zhang, X.1    Wu, D.2    Lai, J.3    Lu, Y.4    Yin, Z.5    Wu, W.6
  • 56
    • 38649102798 scopus 로고    scopus 로고
    • Enhanced dissolution of silymarin/polyvinylpyrrolidone solid dispersion pellets prepared by a one-step fluid-bed coating technique
    • Sun, N., Wei, X., Wu, B., Chen, J., Lu, Y., Wu, W. Enhanced dissolution of silymarin/polyvinylpyrrolidone solid dispersion pellets prepared by a one-step fluid-bed coating technique. Powder Tech, 2008, 82: 72-80.
    • (2008) Powder Tech , vol.82 , pp. 72-80
    • Sun, N.1    Wei, X.2    Wu, B.3    Chen, J.4    Lu, Y.5    Wu, W.6
  • 57
    • 59149085001 scopus 로고    scopus 로고
    • Physical characterization of meloxicam-cyclodextrin inclusion complex pellets prepared by a fluid-bed coating method
    • Lu, Y., Zhang, X., Lai, J., Yin, Z., Wu, W. Physical characterization of meloxicam-cyclodextrin inclusion complex pellets prepared by a fluid-bed coating method. Particuology 2009; 7: 1-8.
    • (2009) Particuology , vol.7 , pp. 1-8
    • Lu, Y.1    Zhang, X.2    Lai, J.3    Yin, Z.4    Wu, W.5
  • 58
    • 84862306688 scopus 로고    scopus 로고
    • Fenofibrate solid dispersion pellets prepared by fluid-bed coating: Physical characterization, improved dissolution and oral bioavailability in beagle dogs
    • Tang, N., Lai, J., Chen, Y-P., Lu, Y., Wu, W. Fenofibrate solid dispersion pellets prepared by fluid-bed coating: physical characterization, improved dissolution and oral bioavailability in beagle dogs. J Chin Pharmaceut Sci 2009; 18: 156-61.
    • (2009) J Chin Pharmaceut Sci , vol.18 , pp. 156-161
    • Tang, N.1    Lai, J.2    Chen, Y.-P.3    Lu, Y.4    Wu, W.5
  • 59
    • 40349116324 scopus 로고    scopus 로고
    • In vitro evaluation and pharmacokinetics in dogs of solid dispersion pellets containing Silybum marianum extract prepared by fluid-bed coating
    • Sun, N., Zhang, X., Lu, Y., Wu, W. In vitro evaluation and pharmacokinetics in dogs of solid dispersion pellets containing Silybum marianum extract prepared by fluid-bed coating. Planta Med 2008; 74: 126-132.
    • (2008) Planta Med , vol.74 , pp. 126-132
    • Sun, N.1    Zhang, X.2    Lu, Y.3    Wu, W.4
  • 68
    • 0034601240 scopus 로고    scopus 로고
    • Improving drug solubility for oral delivery using solid dispersions
    • Leuner, C, Dressman, J. Improving drug solubility for oral delivery using solid dispersions. Eur J Pharm Biopharm 2000; 50:47-60.
    • (2000) Eur J Pharm Biopharm , vol.50 , pp. 47-60
    • Leuner, C.1    Dressman, J.2
  • 83
    • 33747179333 scopus 로고    scopus 로고
    • Strategies for the design of hydrophilic matrix tablets with controlled microenvironmental pH
    • Siepe S, Lueckel B, Kramer A, Ries A, Gurny R. Strategies for the design of hydrophilic matrix tablets with controlled microenvironmental pH. Int J Pharm 2006; 316: 14-20.
    • (2006) Int J Pharm , vol.316 , pp. 14-20
    • Siepe, S.1    Lueckel, B.2    Kramer, A.3    Ries, A.4    Gurny, R.5
  • 84
    • 52249114680 scopus 로고    scopus 로고
    • Modulation of microenvironmental pH and crystallinity of ionizable telmisartan using alkalizers in solid dispersions for controlled release
    • Tran PHL, Tran HTT, Lee B-J. Modulation of microenvironmental pH and crystallinity of ionizable telmisartan using alkalizers in solid dispersions for controlled release. J Control Release 2008; 129: 59-65.
    • (2008) J Control Release , vol.129 , pp. 59-65
    • Tran, P.H.L.1    Tran, H.T.T.2    Lee, B.-J.3
  • 85
    • 62949131342 scopus 로고    scopus 로고
    • Dissolution-modulating mechanism of alkalizers and polymers in a nanoemulsifying solid dispersion containing ionizable and poorly water-soluble drug
    • Tran TTD, Tran PHL, Lee B-J. Dissolution-modulating mechanism of alkalizers and polymers in a nanoemulsifying solid dispersion containing ionizable and poorly water-soluble drug. Eur J Pharm Biopharm 2009; 72: 83-90.
    • (2009) Eur J Pharm Biopharm , vol.72 , pp. 83-90
    • Tran, T.T.D.1    Tran, P.H.L.2    Lee, B.-J.3
  • 86


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.