Enhanced dissolution of silymarin/polyvinylpyrrolidone solid dispersion pellets prepared by a one-step fluid-bed coating technique

Powder Technology

Volumn 182, Issue 1, 2008, Pages 72-80

  Sun, Ningyun ^a   Wei, Xiuli ^a   Wu, Baojian ^a   Chen, Jian ^a   Lu, Yi ^a   Wu, Wei ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Central composite design; Dissolution; Fluid bed; Polyvinyl pyrrolidone; Silymarin; Solid dispersion

Indexed keywords

COPRECIPITATION; DISSOLUTION; DRUG DELIVERY; ETHANOL; NONLINEAR EQUATIONS; POLYNOMIALS;

FLUID-BED; POLYVINYL PYRROLIDONE; SILYMARIN; SOLID DISPERSION;

COATING TECHNIQUES;

ALCOHOL; POVIDONE; SILYMARIN;

COATING TECHNIQUES; COPRECIPITATION; DISSOLUTION; DRUG DELIVERY; ETHANOL; NONLINEAR EQUATIONS; POLYNOMIALS;

AEROSOL; AIRFLOW; ARTICLE; COMPOSITE MATERIAL; DESICCATION; DISPERSION; DISSOLUTION; DRUG COATING; DRUG DESIGN; FLUIDIZED BED; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INDEPENDENT VARIABLE; METHODOLOGY; PELLET EXTRUSION; SCANNING ELECTRON MICROSCOPY; ULTRAVIOLET RADIATION;

EID: 38649102798     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2007.05.029     Document Type: Article

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