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Volumn 8, Issue 7, 2013, Pages

The Efficiency of Homologous Recombination and Non-Homologous End Joining Systems in Repairing Double-Strand Breaks during Cell Cycle Progression

Author keywords

[No Author keywords available]

Indexed keywords

DNA DEPENDENT PROTEIN KINASE; HISTONE H2AX; NUCLEAR PROTEIN; PROTEIN CENP F; RAD51 PROTEIN; UNCLASSIFIED DRUG;

EID: 84880059539     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069061     Document Type: Article
Times cited : (57)

References (44)
  • 2
    • 0242300088 scopus 로고    scopus 로고
    • Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer
    • Vilenchik MM, Knudson AG, (2003) Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer. Proc Natl Acad Sci USA 100: 12871-876.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12871-12876
    • Vilenchik, M.M.1    Knudson, A.G.2
  • 3
    • 0034437901 scopus 로고    scopus 로고
    • Complexity of damage produced by ionizing radiation
    • Ward JF, (2000) Complexity of damage produced by ionizing radiation. Cold Spring Harb Symp Quant Biol 65: 377-382.
    • (2000) Cold Spring Harb Symp Quant Biol , vol.65 , pp. 377-382
    • Ward, J.F.1
  • 4
    • 79956197636 scopus 로고    scopus 로고
    • Delayed repair of radiation induced clustered DNA damage: friend or foe?
    • Eccles LJ, O'Neill P, Lomax ME, (2011) Delayed repair of radiation induced clustered DNA damage: friend or foe? Mutat Res 711: 134-141.
    • (2011) Mutat Res , vol.711 , pp. 134-141
    • Eccles, L.J.1    O'Neill, P.2    Lomax, M.E.3
  • 5
    • 0034753336 scopus 로고    scopus 로고
    • Computational approach for determining the spectrum of DNA damage induced by ionizing radiation
    • Nikjoo H, O'Neill P, Wilson WE, Goodhead DT, (2001) Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiat Res 156: 577-583.
    • (2001) Radiat Res , vol.156 , pp. 577-583
    • Nikjoo, H.1    O'Neill, P.2    Wilson, W.E.3    Goodhead, D.T.4
  • 6
    • 3242881500 scopus 로고    scopus 로고
    • The cellular response to general and programmed DNA double strand breaks
    • Bassing CH, Alt WF, (2004) The cellular response to general and programmed DNA double strand breaks. DNA Repair (Amst) 3: 781-796.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 781-796
    • Bassing, C.H.1    Alt, W.F.2
  • 8
    • 75749130671 scopus 로고    scopus 로고
    • Mechanism of elimination of phosphorylated histone H2AX from chromatin after repair of DNA double-strand breaks
    • Svetlova MP, Solovjeva LV, Tomilin NV, (2010) Mechanism of elimination of phosphorylated histone H2AX from chromatin after repair of DNA double-strand breaks. Mutat Res 685: 54-60.
    • (2010) Mutat Res , vol.685 , pp. 54-60
    • Svetlova, M.P.1    Solovjeva, L.V.2    Tomilin, N.V.3
  • 9
  • 10
    • 0038143321 scopus 로고    scopus 로고
    • Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX
    • Ward IM, Minn K, Jorda KG, Chen J, (2003) Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. J Biol Chem 278: 19579-582.
    • (2003) J Biol Chem , vol.278 , pp. 19579-19582
    • Ward, I.M.1    Minn, K.2    Jorda, K.G.3    Chen, J.4
  • 11
    • 0034739853 scopus 로고    scopus 로고
    • p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
    • Schultz LB, Chehab NH, Malikzay A, Halazonetis TD, (2000) p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J Cell Biol 151: 1381-390.
    • (2000) J Cell Biol , vol.151 , pp. 1381-1390
    • Schultz, L.B.1    Chehab, N.H.2    Malikzay, A.3    Halazonetis, T.D.4
  • 12
    • 0035972194 scopus 로고    scopus 로고
    • Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways
    • Rappold I, Iwabuchi K, Date T, Chen J, (2001) Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways. J Cell Biol 153: 613-620.
    • (2001) J Cell Biol , vol.153 , pp. 613-620
    • Rappold, I.1    Iwabuchi, K.2    Date, T.3    Chen, J.4
  • 13
    • 0035134286 scopus 로고    scopus 로고
    • Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage
    • Anderson L, Henderson C, Adachi Y, (2001) Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage. Mol Cell Biol 21: 1719-729.
    • (2001) Mol Cell Biol , vol.21 , pp. 1719-1729
    • Anderson, L.1    Henderson, C.2    Adachi, Y.3
  • 14
    • 67651162117 scopus 로고    scopus 로고
    • Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation
    • Asaithamby A, Chen DJ, (2009) Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation. Nucleic Acids Res 37: 3912-923.
    • (2009) Nucleic Acids Res , vol.37 , pp. 3912-3923
    • Asaithamby, A.1    Chen, D.J.2
  • 15
    • 0030908093 scopus 로고    scopus 로고
    • "Replication protein A: heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism"
    • Wold MS, (1997) "Replication protein A: heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism". Annual Review of Biochemistry 66 (1): 61-92.
    • (1997) Annual Review of Biochemistry , vol.66 , Issue.1 , pp. 61-92
    • Wold, M.S.1
  • 16
    • 68249125048 scopus 로고    scopus 로고
    • Choreography of recombination proteins during the DNA damage response
    • Lisby M, Rothstein R, (2009) Choreography of recombination proteins during the DNA damage response. DNA Repair 8: 1068-076.
    • (2009) DNA Repair , vol.8 , pp. 1068-1076
    • Lisby, M.1    Rothstein, R.2
  • 17
    • 38049155945 scopus 로고    scopus 로고
    • Regulation of DNA double-strand break repair pathway choice
    • Shrivastav M, De Haro LP, Nickoloff JA, (2005) Regulation of DNA double-strand break repair pathway choice. Cell Res 18: 134-147.
    • (2005) Cell Res , vol.18 , pp. 134-147
    • Shrivastav, M.1    De Haro, L.P.2    Nickoloff, J.A.3
  • 19
    • 13944268723 scopus 로고    scopus 로고
    • The RAD51 gene family, genetic instability and cancer
    • Tracker J, (2005) The RAD51 gene family, genetic instability and cancer. Cancer Lett 219: 125-135.
    • (2005) Cancer Lett , vol.219 , pp. 125-135
    • Tracker, J.1
  • 20
    • 0036789173 scopus 로고    scopus 로고
    • Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody
    • Sedelnikova OA, Rogakou EP, Panyutin IG, Bonner WM, (2002) Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody. Radiat Res 4: 486-492.
    • (2002) Radiat Res , vol.4 , pp. 486-492
    • Sedelnikova, O.A.1    Rogakou, E.P.2    Panyutin, I.G.3    Bonner, W.M.4
  • 21
    • 42949157403 scopus 로고    scopus 로고
    • Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts
    • Asaithamby A, Uematsu N, Chatterjee A, Story MD, Burma S, et al. (2008) Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts. Radiat Res 169: 437-446.
    • (2008) Radiat Res , vol.169 , pp. 437-446
    • Asaithamby, A.1    Uematsu, N.2    Chatterjee, A.3    Story, M.D.4    Burma, S.5
  • 22
    • 70350763838 scopus 로고    scopus 로고
    • ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
    • Beucher A, Birraux J, Tchouandong L, Barton O, Shibata A, et al. (2009) ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. EMBO J 28: 3413-427.
    • (2009) EMBO J , vol.28 , pp. 3413-3427
    • Beucher, A.1    Birraux, J.2    Tchouandong, L.3    Barton, O.4    Shibata, A.5
  • 23
    • 0029096822 scopus 로고
    • CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis
    • Liao H, Winkfein RJ, Mack G, Rattner JB, Yen TJ, (1995) CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis. J Cell Biol 130: 507-18.
    • (1995) J Cell Biol , vol.130 , pp. 507-518
    • Liao, H.1    Winkfein, R.J.2    Mack, G.3    Rattner, J.B.4    Yen, T.J.5
  • 24
    • 33745275634 scopus 로고    scopus 로고
    • Cenp-F (mitosin) is more than a mitotic marker
    • Varis A, Salmela AL, Kallio MJ, (2006) Cenp-F (mitosin) is more than a mitotic marker. Chromosoma 115: 288-295.
    • (2006) Chromosoma , vol.115 , pp. 288-295
    • Varis, A.1    Salmela, A.L.2    Kallio, M.J.3
  • 25
    • 69249232244 scopus 로고    scopus 로고
    • Low-dose DNA damage and replication stress responses quantified by optimized automated single-cell image analysis
    • Mistrik M, Oplustilova L, Lukas J, Bartek J, (2009) Low-dose DNA damage and replication stress responses quantified by optimized automated single-cell image analysis. Cell Cycle 8: 2592-599.
    • (2009) Cell Cycle , vol.8 , pp. 2592-2599
    • Mistrik, M.1    Oplustilova, L.2    Lukas, J.3    Bartek, J.4
  • 26
    • 79953776034 scopus 로고    scopus 로고
    • Image-based quantitative determination of DNA damage signal reveals a threshold for G2 checkpoint activation in response to ionizing radiation
    • Ishikawa A, Yamauchi M, Suzuki K, Yamashita S, (2010) Image-based quantitative determination of DNA damage signal reveals a threshold for G2 checkpoint activation in response to ionizing radiation. Genome Integr 1: 10.
    • (2010) Genome Integr , vol.1 , pp. 10
    • Ishikawa, A.1    Yamauchi, M.2    Suzuki, K.3    Yamashita, S.4
  • 27
    • 40649111377 scopus 로고    scopus 로고
    • A chemical method for fast and sensitive detection of DNA synthesis in vivo
    • Salic A, Mitchison TJ, (2008) A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci USA 105: 2415-420.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2415-2420
    • Salic, A.1    Mitchison, T.J.2
  • 28
    • 47549090286 scopus 로고    scopus 로고
    • Detection of S-phase cell cycle progression using 5-ethynyl-2′-deoxyuridine incorporation with click chemistry, an alternative to using 5-bromo-2′-deoxyuridine antibodies
    • Buck SB, Bradford J, Gee KR, Agnew BJ, Salic A, (2008) Detection of S-phase cell cycle progression using 5-ethynyl-2′-deoxyuridine incorporation with click chemistry, an alternative to using 5-bromo-2′-deoxyuridine antibodies. Biotechniques 44: 927-929.
    • (2008) Biotechniques , vol.44 , pp. 927-929
    • Buck, S.B.1    Bradford, J.2    Gee, K.R.3    Agnew, B.J.4    Salic, A.5
  • 29
    • 56649111359 scopus 로고    scopus 로고
    • Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage
    • Pontarin G, Fijolek A, Pizzo P, Ferraro P, Rampazzo C, et al. (2008) Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage. Proc Natl Acad Sci USA. 105: 17801-17806.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 17801-17806
    • Pontarin, G.1    Fijolek, A.2    Pizzo, P.3    Ferraro, P.4    Rampazzo, C.5
  • 30
    • 12844266749 scopus 로고    scopus 로고
    • "Modeled microgravity" affects cell response to ionizing radiation and increases genomic damage
    • Canova S, Fiorasi F, Mognato M, Grifalconi M, Reddi E, et al. (2005) "Modeled microgravity" affects cell response to ionizing radiation and increases genomic damage. Radiat Res 163: 191-199.
    • (2005) Radiat Res , vol.163 , pp. 191-199
    • Canova, S.1    Fiorasi, F.2    Mognato, M.3    Grifalconi, M.4    Reddi, E.5
  • 31
    • 13844294373 scopus 로고    scopus 로고
    • Different G2/M accumulation in M059J and M059K cells after exposure to DNA double-strand break-inducing agents
    • Holgersson A, Heiden T, Castro J, Edgren MR, Lewensohn R, et al. (2005) Different G2/M accumulation in M059J and M059K cells after exposure to DNA double-strand break-inducing agents. Int J Radiat Oncol Biol Phys. 61(3): 915-21.
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , Issue.3 , pp. 915-921
    • Holgersson, A.1    Heiden, T.2    Castro, J.3    Edgren, M.R.4    Lewensohn, R.5
  • 32
    • 79959948744 scopus 로고    scopus 로고
    • Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells
    • Short SC, Giampieri S, Worku M, Alcaide-German M, Sioftanos G, et al. (2011) Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells. Neuro Oncol 13: 487-99.
    • (2011) Neuro Oncol , vol.13 , pp. 487-499
    • Short, S.C.1    Giampieri, S.2    Worku, M.3    Alcaide-German, M.4    Sioftanos, G.5
  • 33
    • 23744447715 scopus 로고    scopus 로고
    • Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells
    • Kim JS, Krasieva TB, Kurumizaka H, Chen DJ, Taylor AM, et al. (2005) Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells. J Cell Biol 170(3): 341-7.
    • (2005) J Cell Biol , vol.170 , Issue.3 , pp. 341-347
    • Kim, J.S.1    Krasieva, T.B.2    Kurumizaka, H.3    Chen, D.J.4    Taylor, A.M.5
  • 34
    • 52049098230 scopus 로고    scopus 로고
    • Comparison of non-homologous end joining and homologous recombination in human cells
    • Mao Z, Bozzella M, Seluanov A, Gorbunova V, (2008) Comparison of non-homologous end joining and homologous recombination in human cells. DNA Repair 7: 1765-771.
    • (2008) DNA Repair , vol.7 , pp. 1765-1771
    • Mao, Z.1    Bozzella, M.2    Seluanov, A.3    Gorbunova, V.4
  • 35
  • 36
    • 20644471358 scopus 로고    scopus 로고
    • Harmonising the response to DSBs: a new string in the ATM bow
    • Löbrich M, Jeggo PA, (2005) Harmonising the response to DSBs: a new string in the ATM bow. DNA Rep (Amst) 4: 749-759.
    • (2005) DNA Rep (Amst) , vol.4 , pp. 749-759
    • Löbrich, M.1    Jeggo, P.A.2
  • 37
    • 37549006429 scopus 로고    scopus 로고
    • Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2
    • Wu W, Wang M, Wu W, Singh SK, Mussfeldt T, et al. (2008) Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2. DNA Repair (Amst) 7: 329-338.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 329-338
    • Wu, W.1    Wang, M.2    Wu, W.3    Singh, S.K.4    Mussfeldt, T.5
  • 38
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA double-strand break repair during the mammalian cell cycle
    • Rothkamm K, Krüger I, Thompson LH, Löbrich M, (2003) Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol Cell Biol 23: 5706-5715.
    • (2003) Mol Cell Biol , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Krüger, I.2    Thompson, L.H.3    Löbrich, M.4
  • 39
    • 1642556817 scopus 로고    scopus 로고
    • A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity
    • Kühne M, Riballo E, Rief N, Rothkamm K, Jeggo PA, et al. (2004) A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Res 64: 500-508.
    • (2004) Cancer Res , vol.64 , pp. 500-508
    • Kühne, M.1    Riballo, E.2    Rief, N.3    Rothkamm, K.4    Jeggo, P.A.5
  • 40
    • 84874586999 scopus 로고    scopus 로고
    • Homologous chromosomes move and rapidly initiate contact at the sites of double-strand breaks in genes in G0-phase human cells
    • Gandhi M, Evdokimova VN, Cuenco KT, Bakkenist CJ, Nikiforov YE, (2013) Homologous chromosomes move and rapidly initiate contact at the sites of double-strand breaks in genes in G0-phase human cells. Cell Cycle 12(4): 547-52.
    • (2013) Cell Cycle , vol.12 , Issue.4 , pp. 547-552
    • Gandhi, M.1    Evdokimova, V.N.2    Cuenco, K.T.3    Bakkenist, C.J.4    Nikiforov, Y.E.5
  • 41
    • 0142025259 scopus 로고    scopus 로고
    • Interactive competition between homologous recombination and non-homologous end joining
    • Allen C, Halbrook J, Nickoloff JA, (2003) Interactive competition between homologous recombination and non-homologous end joining. Mol Cancer Res 1: 913-920.
    • (2003) Mol Cancer Res , vol.1 , pp. 913-920
    • Allen, C.1    Halbrook, J.2    Nickoloff, J.A.3
  • 42
    • 13444263265 scopus 로고    scopus 로고
    • Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs)
    • Convery E, Shin EK, Ding Q, Wang W, Douglas P, et al. (2005) Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs). Proc Natl Acad Sci USA 102: 1345-350.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1345-1350
    • Convery, E.1    Shin, E.K.2    Ding, Q.3    Wang, W.4    Douglas, P.5
  • 43
    • 0033819217 scopus 로고    scopus 로고
    • Human TP53 from the malignant glioma-derived cell lines M059J and M059K has a cancer-associated mutation in exon 8
    • Anderson CW, Allalunis-Turner MJ, (2000) Human TP53 from the malignant glioma-derived cell lines M059J and M059K has a cancer-associated mutation in exon 8. Radiat Res 154: 473-476.
    • (2000) Radiat Res , vol.154 , pp. 473-476
    • Anderson, C.W.1    Allalunis-Turner, M.J.2
  • 44
    • 8744233919 scopus 로고    scopus 로고
    • After double-strand break induction by UV-A, homologous recombination and non-homologous end joining cooperate at the same DSB if both systems are available
    • Rapp A, Greulich KO, (2004) After double-strand break induction by UV-A, homologous recombination and non-homologous end joining cooperate at the same DSB if both systems are available. J Cell Sci. 117: 4935-45.
    • (2004) J Cell Sci , vol.117 , pp. 4935-4945
    • Rapp, A.1    Greulich, K.O.2


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