Atorvastatin inhibits RhoC function and limits head and neck cancer metastasis

Oral Oncology

Volumn 49, Issue 8, 2013, Pages 778-786

  Islam, Mozaffarul ^a,b   Sharma, Smita ^b   Kumar, Bhavna ^a,b   Teknos, Theodoros N ^a,b  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Geranylation; Head and neck squamous cell carcinoma; HMG COA reductase; Lung metastasis; RhoC

Indexed keywords

ATORVASTATIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN; RHOC PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CELL INVASION; CELL MOTILITY; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

GERANYLATION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HMG-COA REDUCTASE; LUNG METASTASIS; RHOC;

ANIMALS; CARCINOMA, SQUAMOUS CELL; HEAD AND NECK NEOPLASMS; HEPTANOIC ACIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MAP KINASE SIGNALING SYSTEM; MICE; NEOPLASM METASTASIS; PHOSPHORYLATION; PYRROLES; RHO GTP-BINDING PROTEINS; STAT3 TRANSCRIPTION FACTOR;

EID: 84880059155     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2013.04.003     Document Type: Article

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