Targeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinoma

Oral Oncology

Volumn 48, Issue 12, 2012, Pages 1220-1226

  Adachi, Makoto ^a   Cui, Caixia ^a,b   Dodge, Cristina T ^a   Bhayani, Mihir K ^a   Lai, Stephen Y ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b HANGZHOU FIRST PEOPLE'S HOSPITAL   (China)

Author keywords

Head and neck squamous cell carcinoma; HIF 1; Radiation therapy; Radiosensitization; STAT3; Stattic

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN INHIBITOR; STAT3 PROTEIN; STAT3 PROTEIN INHIBITOR; STATTIC; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER MODEL; CANCER RADIOTHERAPY; CELL ASSAY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; RADIOSENSITIZATION; REGULATORY MECHANISM; SQUAMOUS CELL CARCINOMA;

ANIMALS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; DISEASE MODELS, ANIMAL; HEAD AND NECK NEOPLASMS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INHIBITORY CONCENTRATION 50; MICE; RADIATION TOLERANCE; STAT3 TRANSCRIPTION FACTOR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84869500586     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2012.06.006     Document Type: Article

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