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Volumn 7, Issue 7, 2012, Pages

RhoC impacts the metastatic potential and abundance of breast cancer stem cells

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 1; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOC PROTEIN; UNCLASSIFIED DRUG;

EID: 84864249805     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040979     Document Type: Article
Times cited : (61)

References (33)
  • 1
    • 33846425793 scopus 로고    scopus 로고
    • The prognostic role of a gene signature from tumorigenic breast-cancer cells
    • Liu R, Wang X, Chen GY, Dalerba P, Gurney A, et al. (2007) The prognostic role of a gene signature from tumorigenic breast-cancer cells. N Engl J Med 356: 217-226.
    • (2007) N Engl J Med , vol.356 , pp. 217-226
    • Liu, R.1    Wang, X.2    Chen, G.Y.3    Dalerba, P.4    Gurney, A.5
  • 2
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133: 704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3    Eaton, E.N.4    Ayyanan, A.5
  • 3
    • 78149262994 scopus 로고    scopus 로고
    • Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models
    • Liu H, Patel MR, Prescher JA, Patsialou A, Qian D, et al. (2010) Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Proc Natl Acad Sci U S A 107: 18115-18120.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 18115-18120
    • Liu, H.1    Patel, M.R.2    Prescher, J.A.3    Patsialou, A.4    Qian, D.5
  • 4
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, et al. (2007) Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1: 313-323.
    • (2007) Cell Stem Cell , vol.1 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5
  • 5
    • 77956641496 scopus 로고    scopus 로고
    • A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer
    • Pang R, Law WL, Chu AC, Poon JT, Lam CS, et al. (2010) A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer. Cell Stem Cell 6: 603-615.
    • (2010) Cell Stem Cell , vol.6 , pp. 603-615
    • Pang, R.1    Law, W.L.2    Chu, A.C.3    Poon, J.T.4    Lam, C.S.5
  • 6
    • 80054045652 scopus 로고    scopus 로고
    • Rho Proteins in Cancer
    • In: van Golen KL, editors, editor
    • Rosenthal DT, Brenner JC, Merajver SD, (2010) Rho Proteins in Cancer. In: van Golen KL, editors. pp. 29-42 editor. The Rho GTPases in Cancer. New York: Springer New York.
    • (2010) , pp. 29-42
    • Rosenthal, D.T.1    Brenner, J.C.2    Merajver, S.D.3
  • 7
    • 6344231714 scopus 로고    scopus 로고
    • Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility
    • Wheeler AP, Ridley AJ, (2004) Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility. Exp Cell Res 301: 43-49.
    • (2004) Exp Cell Res , vol.301 , pp. 43-49
    • Wheeler, A.P.1    Ridley, A.J.2
  • 8
    • 0034667370 scopus 로고    scopus 로고
    • RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype
    • van Golen KL, Wu ZF, Qiao XT, Bao LW, Merajver SD, (2000) RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype. Cancer Res 60: 5832-5838.
    • (2000) Cancer Res , vol.60 , pp. 5832-5838
    • van Golen, K.L.1    Wu, Z.F.2    Qiao, X.T.3    Bao, L.W.4    Merajver, S.D.5
  • 9
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • Clark EA, Golub TR, Lander ES, Hynes RO, (2000) Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406: 532-535.
    • (2000) Nature , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 10
    • 1042278714 scopus 로고    scopus 로고
    • A definitive role of RhoC in metastasis of orthotopic lung cancer in mice
    • Ikoma T, Takahashi T, Nagano S, Li YM, Ohno Y, et al. (2004) A definitive role of RhoC in metastasis of orthotopic lung cancer in mice. Clin Cancer Res 10: 1192-1200.
    • (2004) Clin Cancer Res , vol.10 , pp. 1192-1200
    • Ikoma, T.1    Takahashi, T.2    Nagano, S.3    Li, Y.M.4    Ohno, Y.5
  • 12
    • 24344486013 scopus 로고    scopus 로고
    • RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
    • Hakem A, Sanchez-Sweatman O, You-Ten A, Duncan G, Wakeham A, et al. (2005) RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis. Genes Dev 19: 1974-1979.
    • (2005) Genes Dev , vol.19 , pp. 1974-1979
    • Hakem, A.1    Sanchez-Sweatman, O.2    You-Ten, A.3    Duncan, G.4    Wakeham, A.5
  • 13
    • 25844484093 scopus 로고    scopus 로고
    • RhoC-GTPase is a novel tissue biomarker associated with biologically aggressive carcinomas of the breast
    • Kleer CG, Griffith KA, Sabel MS, Gallagher G, van Golen KL, et al. (2005) RhoC-GTPase is a novel tissue biomarker associated with biologically aggressive carcinomas of the breast. Breast Cancer Res Treat 93: 101-110.
    • (2005) Breast Cancer Res Treat , vol.93 , pp. 101-110
    • Kleer, C.G.1    Griffith, K.A.2    Sabel, M.S.3    Gallagher, G.4    van Golen, K.L.5
  • 14
    • 0032835343 scopus 로고    scopus 로고
    • A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype
    • van Golen KL, Davies S, Wu ZF, Wang Y, Bucana CD, et al. (1999) A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype. Clin Cancer Res 5: 2511-2519.
    • (1999) Clin Cancer Res , vol.5 , pp. 2511-2519
    • van Golen, K.L.1    Davies, S.2    Wu, Z.F.3    Wang, Y.4    Bucana, C.D.5
  • 16
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, et al. (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1: 555-567.
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3    Monville, F.4    Dutcher, J.5
  • 17
    • 74949129868 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer
    • Charafe-Jauffret E, Ginestier C, Iovino F, Tarpin C, Diebel M, et al. (2010) Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin Cancer Res 16: 45-55.
    • (2010) Clin Cancer Res , vol.16 , pp. 45-55
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3    Tarpin, C.4    Diebel, M.5
  • 18
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • Ridley AJ, Hall A, (1992) The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70: 389-399.
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 19
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes CD, Hall A, (1995) Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81: 53-62.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 20
    • 70349305426 scopus 로고    scopus 로고
    • Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity
    • Dietrich KA, Schwarz R, Liska M, Grass S, Menke A, et al. (2009) Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity. Biol Chem 390: 1063-1077.
    • (2009) Biol Chem , vol.390 , pp. 1063-1077
    • Dietrich, K.A.1    Schwarz, R.2    Liska, M.3    Grass, S.4    Menke, A.5
  • 21
    • 25444443688 scopus 로고    scopus 로고
    • Modelling glandular epithelial cancers in three-dimensional cultures
    • Debnath J, Brugge JS, (2005) Modelling glandular epithelial cancers in three-dimensional cultures. Nat Rev Cancer 5: 675-688.
    • (2005) Nat Rev Cancer , vol.5 , pp. 675-688
    • Debnath, J.1    Brugge, J.S.2
  • 22
    • 34247864012 scopus 로고    scopus 로고
    • Three-dimensional culture models of normal and malignant breast epithelial cells
    • Lee GY, Kenny PA, Lee EH, Bissell MJ, (2007) Three-dimensional culture models of normal and malignant breast epithelial cells. Nat Methods 4: 359-365.
    • (2007) Nat Methods , vol.4 , pp. 359-365
    • Lee, G.Y.1    Kenny, P.A.2    Lee, E.H.3    Bissell, M.J.4
  • 23
    • 34248650697 scopus 로고    scopus 로고
    • The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression
    • Kenny PA, Lee GY, Myers CA, Neve RM, Semeiks JR, et al. (2007) The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression. Mol Oncol 1: 84-96.
    • (2007) Mol Oncol , vol.1 , pp. 84-96
    • Kenny, P.A.1    Lee, G.Y.2    Myers, C.A.3    Neve, R.M.4    Semeiks, J.R.5
  • 27
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ, (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65: 10946-10951.
    • (2005) Cancer Res , vol.65 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 28
    • 54049096261 scopus 로고    scopus 로고
    • HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
    • Korkaya H, Paulson A, Iovino F, Wicha MS, (2008) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 27: 6120-6130.
    • (2008) Oncogene , vol.27 , pp. 6120-6130
    • Korkaya, H.1    Paulson, A.2    Iovino, F.3    Wicha, M.S.4
  • 30
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, et al. (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138: 645-659.
    • (2009) Cell , vol.138 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3    Tao, K.4    Kuperwasser, C.5
  • 32
    • 0035480005 scopus 로고    scopus 로고
    • Tissue microarrays (TMAs) for high-throughput molecular pathology research
    • Nocito A, Kononen J, Kallioniemi OP, Sauter G, (2001) Tissue microarrays (TMAs) for high-throughput molecular pathology research. Int J Cancer 94: 1-5.
    • (2001) Int J Cancer , vol.94 , pp. 1-5
    • Nocito, A.1    Kononen, J.2    Kallioniemi, O.P.3    Sauter, G.4
  • 33
    • 29844434293 scopus 로고    scopus 로고
    • Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis
    • McCabe A, Dolled-Filhart M, Camp RL, Rimm DL, (2005) Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis. J Natl Cancer Inst 97: 1808-1815.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1808-1815
    • McCabe, A.1    Dolled-Filhart, M.2    Camp, R.L.3    Rimm, D.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.