Calmodulin kinase IV-dependent CREB activation is required for neuroprotection via NMDA receptor-PSD95 disruption

Journal of Neurochemistry

Volumn 126, Issue 2, 2013, Pages 274-287

  Bell, Karen F S ^a   Bent, Russell J ^a   Meese Tamuri, Saira ^a   Ali, Alicia ^a   Forder, Joan P ^a   Aarts, Michelle M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

calcium signaling; calmodulin kinase; neuroprotection; NMDA; PSD 95; trophic signaling

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IV; CALCIUM ION; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PEPTIDE; POSTSYNAPTIC DENSITY PROTEIN 95; TAT NR2B9C PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CALCIUM SIGNALING; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXCITOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT;

CALCIUM SIGNALING; CALMODULIN KINASE; NEUROPROTECTION; NMDA; PSD-95; TROPHIC SIGNALING;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; ANOXIA; BRAIN INFARCTION; CALCIUM CHANNEL BLOCKERS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 4; CELLS, CULTURED; CEREBRAL CORTEX; CREB-BINDING PROTEIN; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; ENZYME ACTIVATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GLUCOSE; INFARCTION, MIDDLE CEREBRAL ARTERY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; NEURONS; NIMODIPINE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; TIME FACTORS;

RATTUS;

EID: 84879990014     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12176     Document Type: Article

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