-
2
-
-
42449114966
-
Transcriptional control of human p53-regulated genes
-
doi:10.1038/nrm2395. PubMed: 18431400
-
Riley T, Sontag E, Chen P, Levine A, (2008) Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol 9: 402-412. doi:10.1038/nrm2395. PubMed: 18431400.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 402-412
-
-
Riley, T.1
Sontag, E.2
Chen, P.3
Levine, A.4
-
3
-
-
77955345508
-
p53 at a glance
-
doi:10.1242/jcs.064501. PubMed: 20940128
-
Brady CA, Attardi LD, (2010) p53 at a glance. J Cell Sci 123: 2527-2532. doi:10.1242/jcs.064501. PubMed: 20940128.
-
(2010)
J Cell Sci
, vol.123
, pp. 2527-2532
-
-
Brady, C.A.1
Attardi, L.D.2
-
4
-
-
70349459599
-
p53 and metabolism
-
doi:10.1038/nrc2715. PubMed: 19759539
-
Vousden KH, Ryan KM, (2009) p53 and metabolism. Nat Rev Cancer 9: 691-700. doi:10.1038/nrc2715. PubMed: 19759539.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 691-700
-
-
Vousden, K.H.1
Ryan, K.M.2
-
6
-
-
2442494895
-
The common and distinct target genes of the p53 family transcription factors
-
doi:10.1007/s00018-003-3304-4. PubMed: 15095006
-
Harms K, Nozell S, Chen X, (2004) The common and distinct target genes of the p53 family transcription factors. Cell Mol Life Sci 61: 822-842. doi:10.1007/s00018-003-3304-4. PubMed: 15095006.
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 822-842
-
-
Harms, K.1
Nozell, S.2
Chen, X.3
-
7
-
-
84894892882
-
63 and 73, the Ancestors of p53 Cold Spring Harbor Perspectives in Biology 2
-
Dotsch V, Bernassola F, Coutandin D, Candi E, Melino G, (2010): 63 and 73, the Ancestors of p53 Cold Spring Harbor Perspectives in Biology 2.
-
(2010)
The Ancestors of p53
-
-
Dotsch, V.1
Bernassola, F.2
Coutandin, D.3
Candi, E.4
Melino, G.5
-
8
-
-
34547753615
-
p63 and p73 in human cancer: defining the network
-
doi:10.1038/sj.onc.1210337. PubMed: 17334395
-
DeYoung MP, Ellisen LW, (2007) p63 and p73 in human cancer: defining the network. Oncogene 26: 5169-5183. doi:10.1038/sj.onc.1210337. PubMed: 17334395.
-
(2007)
Oncogene
, vol.26
, pp. 5169-5183
-
-
DeYoung, M.P.1
Ellisen, L.W.2
-
9
-
-
33646798450
-
p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress
-
doi:10.1038/sj.cdd.4401914. PubMed: 16601753
-
Murray-Zmijewski F, Lane DP, Bourdon JC, (2006) p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress. Cell Death Differ 13: 962-972. doi:10.1038/sj.cdd.4401914. PubMed: 16601753.
-
(2006)
Cell Death Differ
, vol.13
, pp. 962-972
-
-
Murray-Zmijewski, F.1
Lane, D.P.2
Bourdon, J.C.3
-
10
-
-
76549137189
-
Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences
-
doi:10.1073/pnas.0909129107. PubMed: 20080630
-
Menendez D, Inga A, Resnick MA, (2010) Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences. Proc Natl Acad Sci U S A 107: 1500-1505. doi:10.1073/pnas.0909129107. PubMed: 20080630.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 1500-1505
-
-
Menendez, D.1
Inga, A.2
Resnick, M.A.3
-
11
-
-
77956320240
-
The Coordinated P53 and Estrogen Receptor Cis-Regulation at an FLT1 Promoter SNP Is Specific to Genotoxic Stress and Estrogenic Compound
-
PubMed: 20422012
-
Ciribilli Y, Andreotti V, Menendez D, Langen JS, Schoenfelder G, et al. (2010) The Coordinated P53 and Estrogen Receptor Cis-Regulation at an FLT1 Promoter SNP Is Specific to Genotoxic Stress and Estrogenic Compound. PLOS ONE 5: e10236. PubMed: 20422012.
-
(2010)
PLOS ONE
, vol.5
-
-
Ciribilli, Y.1
Andreotti, V.2
Menendez, D.3
Langen, J.S.4
Schoenfelder, G.5
-
12
-
-
0026849821
-
Definition of a consensus binding site for p53
-
doi:10.1038/ng0492-45. PubMed: 1301998
-
el-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B, (1992) Definition of a consensus binding site for p53. Nat Genet 1: 45-49. doi:10.1038/ng0492-45. PubMed: 1301998.
-
(1992)
Nat Genet
, vol.1
, pp. 45-49
-
-
el-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
13
-
-
46249084702
-
Noncanonical DNA Motifs as Transactivation Targets by Wild Type and Mutant p53
-
PubMed: 18714371
-
Jordan JJ, Menendez D, Inga A, Noureddine M, Bell D, et al. (2008) Noncanonical DNA Motifs as Transactivation Targets by Wild Type and Mutant p53. PLOS Genet 4: e1000104. PubMed: 18714371.
-
(2008)
PLOS Genet
, vol.4
-
-
Jordan, J.J.1
Menendez, D.2
Inga, A.3
Noureddine, M.4
Bell, D.5
-
14
-
-
80052032331
-
Potentiating the p53 network
-
PubMed: 20670604
-
Menendez D, Inga A, Resnick MA, (2010) Potentiating the p53 network. Discov Med 10: 94-100. PubMed: 20670604.
-
(2010)
Discov Med
, vol.10
, pp. 94-100
-
-
Menendez, D.1
Inga, A.2
Resnick, M.A.3
-
15
-
-
0030930366
-
A model for p53-induced apoptosis
-
doi:10.1038/38525. PubMed: 9305847
-
Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B, (1997) A model for p53-induced apoptosis. Nature 389: 300-305. doi:10.1038/38525. PubMed: 9305847.
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
16
-
-
0035266127
-
Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species
-
PubMed: 11280728, PubMed, CAA
-
Donald SP, Sun XY, Hu, CAA, Yu J, Mei JM, et al (2001) Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species. Cancer Res 61: 1810-1815. PubMed: 11280728.
-
(2001)
Cancer Res
, vol.61
, pp. 1810-1815
-
-
Donald, S.P.1
Sun, X.Y.2
Hu, C.A.A.3
Yu, J.4
Mei, J.M.5
-
17
-
-
77950890848
-
Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy
-
doi:10.1093/carcin/bgp299. PubMed: 19942609
-
Zabirnyk O, Liu W, Khalil S, Sharma A, Phang JM, (2010) Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy. Carcinogenesis 31: 446-454. doi:10.1093/carcin/bgp299. PubMed: 19942609.
-
(2010)
Carcinogenesis
, vol.31
, pp. 446-454
-
-
Zabirnyk, O.1
Liu, W.2
Khalil, S.3
Sharma, A.4
Phang, J.M.5
-
18
-
-
1942520427
-
Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses
-
doi:10.1007/s10038-003-0122-3. PubMed: 14986171
-
Yoon KA, Nakamura Y, Arakawa H, (2004) Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses. J Hum Genet 49: 134-140. doi:10.1007/s10038-003-0122-3. PubMed: 14986171.
-
(2004)
J Hum Genet
, vol.49
, pp. 134-140
-
-
Yoon, K.A.1
Nakamura, Y.2
Arakawa, H.3
-
19
-
-
44849109711
-
Novel function for hydroxyproline oxidase in apoptosis through generation of reactive oxygen species
-
doi:10.1074/jbc.M702181200. PubMed: 18287100
-
Cooper SK, Pandhare J, Donald SP, Phang JM, (2008) Novel function for hydroxyproline oxidase in apoptosis through generation of reactive oxygen species. J Biol Chem 283: 10485-10492. doi:10.1074/jbc.M702181200. PubMed: 18287100.
-
(2008)
J Biol Chem
, vol.283
, pp. 10485-10492
-
-
Cooper, S.K.1
Pandhare, J.2
Donald, S.P.3
Phang, J.M.4
-
20
-
-
67349172713
-
Activation of NFAT signal by p53-K120R mutant
-
doi:10.1016/j.febslet.2009.04.041. PubMed: 19416725
-
Shinmen N, Koshida T, Kumazawa T, Sato K, Shimada H, et al. (2009) Activation of NFAT signal by p53-K120R mutant. FEBS Lett 583: 1916-1922. doi:10.1016/j.febslet.2009.04.041. PubMed: 19416725.
-
(2009)
FEBS Lett
, vol.583
, pp. 1916-1922
-
-
Shinmen, N.1
Koshida, T.2
Kumazawa, T.3
Sato, K.4
Shimada, H.5
-
21
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
doi:10.1126/science.282.5393.1497. PubMed: 9822382
-
Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, et al. (1998) Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282: 1497-1501. doi:10.1126/science.282.5393.1497. PubMed: 9822382.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
-
22
-
-
0017259817
-
Establishment of a human carcinoembryonic antigen-producing colon adenocarcinoma cell line
-
PubMed: 1260746
-
Drewinko B, Romsdahl MM, Yang LY, Ahearn MJ, Trujillo JM, (1976) Establishment of a human carcinoembryonic antigen-producing colon adenocarcinoma cell line. Cancer Res 36: 467-475. PubMed: 1260746.
-
(1976)
Cancer Res
, vol.36
, pp. 467-475
-
-
Drewinko, B.1
Romsdahl, M.M.2
Yang, L.Y.3
Ahearn, M.J.4
Trujillo, J.M.5
-
23
-
-
24344448690
-
Expression and activity of vascular endothelial growth factor and metalloproteinases in alveolar and embryonal rhabdomyosarcoma cell lines
-
PubMed: 16077930
-
Onisto M, Slongo ML, Gregnanin L, Gastaldi T, Carli M, et al. (2005) Expression and activity of vascular endothelial growth factor and metalloproteinases in alveolar and embryonal rhabdomyosarcoma cell lines. Int J Oncol 27: 791-798. PubMed: 16077930.
-
(2005)
Int J Oncol
, vol.27
, pp. 791-798
-
-
Onisto, M.1
Slongo, M.L.2
Gregnanin, L.3
Gastaldi, T.4
Carli, M.5
-
24
-
-
84856032160
-
Inhibition of Akt signaling in hepatoma cells induces apoptotic cell death independent of Akt activation status
-
doi:10.1007/s10637-010-9486-3. PubMed: 20628892
-
Buontempo F, Ersahin T, Missiroli S, Senturk S, Etro D, et al. (2011) Inhibition of Akt signaling in hepatoma cells induces apoptotic cell death independent of Akt activation status. Invest New Drugs 29: 1303-1313. doi:10.1007/s10637-010-9486-3. PubMed: 20628892.
-
(2011)
Invest New Drugs
, vol.29
, pp. 1303-1313
-
-
Buontempo, F.1
Ersahin, T.2
Missiroli, S.3
Senturk, S.4
Etro, D.5
-
25
-
-
0018718742
-
Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line
-
doi:10.1038/282615a0. PubMed: 233137
-
Aden DP, Fogel A, Plotkin S, Damjanov I, Knowles BB, (1979) Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature 282: 615-616. doi:10.1038/282615a0. PubMed: 233137.
-
(1979)
Nature
, vol.282
, pp. 615-616
-
-
Aden, D.P.1
Fogel, A.2
Plotkin, S.3
Damjanov, I.4
Knowles, B.B.5
-
26
-
-
57349100487
-
MicroRNA alterations in head and neck squamous cell carcinoma
-
doi:10.1002/ijc.23831. PubMed: 18798260
-
Chang SS, Jiang WW, Smith I, Poeta LM, Begum S, et al. (2008) MicroRNA alterations in head and neck squamous cell carcinoma. Int J Cancer 123: 2791-2797. doi:10.1002/ijc.23831. PubMed: 18798260.
-
(2008)
Int J Cancer
, vol.123
, pp. 2791-2797
-
-
Chang, S.S.1
Jiang, W.W.2
Smith, I.3
Poeta, L.M.4
Begum, S.5
-
27
-
-
33750378033
-
Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma
-
doi:10.1158/0008-5472.CAN-06-1619. PubMed: 17018588
-
DeYoung MP, Johannessen CM, Leong CO, Faquin W, Rocco JW, et al. (2006) Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma. Cancer Res 66: 9362-9368. doi:10.1158/0008-5472.CAN-06-1619. PubMed: 17018588.
-
(2006)
Cancer Res
, vol.66
, pp. 9362-9368
-
-
DeYoung, M.P.1
Johannessen, C.M.2
Leong, C.O.3
Faquin, W.4
Rocco, J.W.5
-
28
-
-
30344450404
-
p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis
-
doi:10.1016/j.ccr.2005.12.013. PubMed: 16413471
-
Rocco JW, Leong CO, Kuperwasser N, DeYoung MP, Ellisen LW, (2006) p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis. Cancer Cell 9: 45-56. doi:10.1016/j.ccr.2005.12.013. PubMed: 16413471.
-
(2006)
Cancer Cell
, vol.9
, pp. 45-56
-
-
Rocco, J.W.1
Leong, C.O.2
Kuperwasser, N.3
DeYoung, M.P.4
Ellisen, L.W.5
-
29
-
-
0026510193
-
Oncogenic forms of p53 inhibit p53-regulated gene expression
-
doi:10.1126/science.1589764. PubMed: 1589764
-
Kern SE, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW, et al. (1992) Oncogenic forms of p53 inhibit p53-regulated gene expression. Science 256: 827-830. doi:10.1126/science.1589764. PubMed: 1589764.
-
(1992)
Science
, vol.256
, pp. 827-830
-
-
Kern, S.E.1
Pietenpol, J.A.2
Thiagalingam, S.3
Seymour, A.4
Kinzler, K.W.5
-
30
-
-
0034903337
-
In vivo site-directed mutagenesis using oligonucleotides
-
doi:10.1038/90837. PubMed: 11479573
-
Storici F, Lewis LK, Resnick MA, (2001) In vivo site-directed mutagenesis using oligonucleotides. Nat Biotechnol 19: 773-776. doi:10.1038/90837. PubMed: 11479573.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 773-776
-
-
Storici, F.1
Lewis, L.K.2
Resnick, M.A.3
-
31
-
-
0030934778
-
Determining mutational fingerprints at the human p53 locus with a yeast functional assay: a new tool for molecular epidemiology
-
doi:10.1038/sj.onc.1200952. PubMed: 9178891
-
Inga A, Iannone R, Monti P, Molina F, Bolognesi M, et al. (1997) Determining mutational fingerprints at the human p53 locus with a yeast functional assay: a new tool for molecular epidemiology. Oncogene 14: 1307-1313. doi:10.1038/sj.onc.1200952. PubMed: 9178891.
-
(1997)
Oncogene
, vol.14
, pp. 1307-1313
-
-
Inga, A.1
Iannone, R.2
Monti, P.3
Molina, F.4
Bolognesi, M.5
-
32
-
-
0036892060
-
Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence
-
doi:10.1128/MCB.22.24.8612-8625.2002. PubMed: 12446780
-
Inga A, Storici F, Darden TA, Resnick MA, (2002) Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence. Mol Cell Biol 22: 8612-8625. doi:10.1128/MCB.22.24.8612-8625.2002. PubMed: 12446780.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8612-8625
-
-
Inga, A.1
Storici, F.2
Darden, T.A.3
Resnick, M.A.4
-
33
-
-
34147204571
-
A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1
-
doi:10.1128/MCB.01742-06. PubMed: 17242190
-
Menendez D, Inga A, Snipe J, Krysiak O, Schönfelder G, et al. (2007) A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1. Mol Cell Biol 27: 2590-2600. doi:10.1128/MCB.01742-06. PubMed: 17242190.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2590-2600
-
-
Menendez, D.1
Inga, A.2
Snipe, J.3
Krysiak, O.4
Schönfelder, G.5
-
34
-
-
0037173059
-
The p53MH algorithm and its application in detecting p53-responsive genes
-
doi:10.1073/pnas.132268899. PubMed: 12077306
-
Hoh J, Jin S, Parrado T, Edington J, Levine AJ, et al. (2002) The p53MH algorithm and its application in detecting p53-responsive genes. Proc Natl Acad Sci U S A 99: 8467-8472. doi:10.1073/pnas.132268899. PubMed: 12077306.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8467-8472
-
-
Hoh, J.1
Jin, S.2
Parrado, T.3
Edington, J.4
Levine, A.J.5
-
35
-
-
34248231113
-
p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
-
doi:10.1186/1471-2105-8-20. PubMed: 17430565
-
Sbisà E, Catalano D, Grillo G, Licciulli F, Turi A, et al. (2007) p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data. BMC Bioinformatics 8 (Suppl 1):: S20. doi:10.1186/1471-2105-8-20. PubMed: 17430565.
-
(2007)
BMC Bioinformatics
, vol.8
, Issue.SUPPL. 1
-
-
Sbisà, E.1
Catalano, D.2
Grillo, G.3
Licciulli, F.4
Turi, A.5
-
36
-
-
0032825452
-
Estimating transcription factor bindability on DNA
-
doi:10.1093/bioinformatics/15.7.622. PubMed: 10487870
-
Tsunoda T, Takagi T, (1999) Estimating transcription factor bindability on DNA. Bioinformatics 15: 622-630. doi:10.1093/bioinformatics/15.7.622. PubMed: 10487870.
-
(1999)
Bioinformatics
, vol.15
, pp. 622-630
-
-
Tsunoda, T.1
Takagi, T.2
-
37
-
-
46249084702
-
Noncanonical DNA motifs as transactivation targets by wild type and mutant p53
-
PubMed: 18714371
-
Jordan JJ, Menendez D, Inga A, Noureddine M, Bell DA, et al. (2008) Noncanonical DNA motifs as transactivation targets by wild type and mutant p53. PLOS Genet 4: e1000104. PubMed: 18714371.
-
(2008)
PLOS Genet
, vol.4
-
-
Jordan, J.J.1
Menendez, D.2
Inga, A.3
Noureddine, M.4
Bell, D.A.5
-
38
-
-
40849086158
-
Identification of a p53-response element in the promoter of the proline oxidase gene
-
doi:10.1016/j.bbrc.2008.01.171. PubMed: 18279664
-
Maxwell SA, Kochevar GJ, (2008) Identification of a p53-response element in the promoter of the proline oxidase gene. Biochem Biophys Res Commun 369: 308-313. doi:10.1016/j.bbrc.2008.01.171. PubMed: 18279664.
-
(2008)
Biochem Biophys Res Commun
, vol.369
, pp. 308-313
-
-
Maxwell, S.A.1
Kochevar, G.J.2
-
39
-
-
30344478870
-
A global map of p53 transcription-factor binding sites in the human genome
-
doi:10.1016/j.cell.2005.10.043. PubMed: 16413492
-
Wei CL, Wu Q, Vega VB, Chiu KP, Ng P, et al. (2006) A global map of p53 transcription-factor binding sites in the human genome. Cell 124: 207-219. doi:10.1016/j.cell.2005.10.043. PubMed: 16413492.
-
(2006)
Cell
, vol.124
, pp. 207-219
-
-
Wei, C.L.1
Wu, Q.2
Vega, V.B.3
Chiu, K.P.4
Ng, P.5
-
40
-
-
46349094389
-
Characterization of genome-wide p53-binding sites upon stress response
-
doi:10.1093/nar/gkn232. PubMed: 18474530
-
Smeenk L, van Heeringen SJ, Koeppel M, van Driel MA, Bartels SJ, et al. (2008) Characterization of genome-wide p53-binding sites upon stress response. Nucleic Acids Res 36: 3639-3654. doi:10.1093/nar/gkn232. PubMed: 18474530.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 3639-3654
-
-
Smeenk, L.1
van Heeringen, S.J.2
Koeppel, M.3
van Driel, M.A.4
Bartels, S.J.5
-
41
-
-
2442426243
-
Delitto perfetto targeted mutagenesis in yeast with oligonucleotides
-
Storici F, Resnick MA, (2003) Delitto perfetto targeted mutagenesis in yeast with oligonucleotides. Genet Eng (N Y)25: 189-207.
-
(2003)
Genet Eng (N Y)
, vol.25
, pp. 189-207
-
-
Storici, F.1
Resnick, M.A.2
-
42
-
-
84876570838
-
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis
-
doi:10.1093/nar/gks1033. PubMed: 23161690
-
Leroy B, Fournier JL, Ishioka C, Monti P, Inga A, et al. (2013) The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis. Nucleic Acids Res 41: D962-D969. doi:10.1093/nar/gks1033. PubMed: 23161690.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Leroy, B.1
Fournier, J.L.2
Ishioka, C.3
Monti, P.4
Inga, A.5
-
43
-
-
52649137098
-
A gene signature-based approach identifies mTOR as a regulator of p73
-
doi:10.1128/MCB.00305-08. PubMed: 18678646
-
Rosenbluth JM, Mays DJ, Pino MF, Tang LJ, Pietenpol JA, (2008) A gene signature-based approach identifies mTOR as a regulator of p73. Mol Cell Biol 28: 5951-5964. doi:10.1128/MCB.00305-08. PubMed: 18678646.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5951-5964
-
-
Rosenbluth, J.M.1
Mays, D.J.2
Pino, M.F.3
Tang, L.J.4
Pietenpol, J.A.5
-
44
-
-
39049184688
-
TP63 gene in stress response and carcinogenesis: a broader role than expected
-
PubMed: 17182369
-
Petitjean A, Hainaut P, Caron de Fromentel C, (2006) TP63 gene in stress response and carcinogenesis: a broader role than expected. Bull Cancer 93: E126-E135. PubMed: 17182369.
-
(2006)
Bull Cancer
, vol.93
-
-
Petitjean, A.1
Hainaut, P.2
Caron de Fromentel, C.3
-
45
-
-
79954419480
-
DeltaNp63 is an ectodermal gatekeeper of epidermal morphogenesis
-
doi:10.1038/cdd.2010.159. PubMed: 21127502
-
Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, et al. (2011) DeltaNp63 is an ectodermal gatekeeper of epidermal morphogenesis. Cell Death Differ 18: 887-896. doi:10.1038/cdd.2010.159. PubMed: 21127502.
-
(2011)
Cell Death Differ
, vol.18
, pp. 887-896
-
-
Shalom-Feuerstein, R.1
Lena, A.M.2
Zhou, H.3
De La Forest Divonne, S.4
Van Bokhoven, H.5
-
46
-
-
0037377761
-
The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
-
doi:10.1128/MCB.23.7.2264-2276.2003. PubMed: 12640112
-
Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA, (2003) The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol Cell Biol 23: 2264-2276. doi:10.1128/MCB.23.7.2264-2276.2003. PubMed: 12640112.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2264-2276
-
-
Westfall, M.D.1
Mays, D.J.2
Sniezek, J.C.3
Pietenpol, J.A.4
-
47
-
-
13244283006
-
The expression of TA and DeltaNp63 are regulated by different mechanisms in liver cells
-
doi:10.1038/sj.onc.1208215. PubMed: 15543231
-
Petitjean A, Cavard C, Shi H, Tribollet V, Hainaut P, et al. (2005) The expression of TA and DeltaNp63 are regulated by different mechanisms in liver cells. Oncogene 24: 512-519. doi:10.1038/sj.onc.1208215. PubMed: 15543231.
-
(2005)
Oncogene
, vol.24
, pp. 512-519
-
-
Petitjean, A.1
Cavard, C.2
Shi, H.3
Tribollet, V.4
Hainaut, P.5
-
48
-
-
0017385444
-
Proline oxidase in cultured mammalian cells
-
doi:10.1002/jcp.1040910306. PubMed: 558989
-
Downing SJ, Phang JM, Kowaloff EM, Valle D, Smith RJ, (1977) Proline oxidase in cultured mammalian cells. J Cell Physiol 91: 369-376. doi:10.1002/jcp.1040910306. PubMed: 558989.
-
(1977)
J Cell Physiol
, vol.91
, pp. 369-376
-
-
Downing, S.J.1
Phang, J.M.2
Kowaloff, E.M.3
Valle, D.4
Smith, R.J.5
-
49
-
-
70349438905
-
The expanding universe of p53 targets
-
doi:10.1038/nrc2730. PubMed: 19776742
-
Menendez D, Inga A, Resnick MA, (2009) The expanding universe of p53 targets. Nat Rev Cancer 9: 724-737. doi:10.1038/nrc2730. PubMed: 19776742.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 724-737
-
-
Menendez, D.1
Inga, A.2
Resnick, M.A.3
-
50
-
-
53849096017
-
The metabolism of proline, a stress substrate, modulates carcinogenic pathways
-
doi:10.1007/s00726-008-0063-4. PubMed: 18401543
-
Phang JM, Donald SP, Pandhare J, Liu YM, (2008) The metabolism of proline, a stress substrate, modulates carcinogenic pathways. Amino Acids 35: 681-690. doi:10.1007/s00726-008-0063-4. PubMed: 18401543.
-
(2008)
Amino Acids
, vol.35
, pp. 681-690
-
-
Phang, J.M.1
Donald, S.P.2
Pandhare, J.3
Liu, Y.M.4
-
51
-
-
77955619986
-
Proline Metabolism and Microenvironmental Stress
-
PubMed: 20415579
-
Phang JM, Liu W, Zabirnyk O, (2010) Proline Metabolism and Microenvironmental Stress. Annu Rev Nutr, Vol 3030:: 441-463. PubMed: 20415579.
-
(2010)
Annu Rev Nutr
, vol.30
, pp. 441-463
-
-
Phang, J.M.1
Liu, W.2
Zabirnyk, O.3
-
52
-
-
79953159004
-
Sequence-dependent cooperative binding of p53 to DNA targets and its relationship to the structural properties of the DNA targets
-
doi:10.1093/nar/gkq1044. PubMed: 21071400
-
Beno I, Rosenthal K, Levitine M, Shaulov L, Haran TE, (2011) Sequence-dependent cooperative binding of p53 to DNA targets and its relationship to the structural properties of the DNA targets. Nucleic Acids Res 39: 1919-1932. doi:10.1093/nar/gkq1044. PubMed: 21071400.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1919-1932
-
-
Beno, I.1
Rosenthal, K.2
Levitine, M.3
Shaulov, L.4
Haran, T.E.5
-
53
-
-
84865985192
-
Low-level p53 expression changes transactivation rules and reveals superactivating sequences
-
PubMed: 22908277
-
Jordan JJ, Menendez D, Sharav J, Beno I, Rosenthal K, et al. (2012) Low-level p53 expression changes transactivation rules and reveals superactivating sequences. Proc Natl Acad Sci U S A, 109: 14387-92. PubMed: 22908277.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 14387-14392
-
-
Jordan, J.J.1
Menendez, D.2
Sharav, J.3
Beno, I.4
Rosenthal, K.5
-
54
-
-
70349438905
-
The expanding universe of p53 targets
-
doi:10.1038/nrc2730. PubMed: 19776742
-
Menendez D, Inga A, Resnick MA, (2009) The expanding universe of p53 targets. Nat Rev Cancer 9: 724-737. doi:10.1038/nrc2730. PubMed: 19776742.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 724-737
-
-
Menendez, D.1
Inga, A.2
Resnick, M.A.3
-
55
-
-
38949187278
-
Functional evolution of the p53 regulatory network through its target response elements
-
doi:10.1073/pnas.0704694105. PubMed: 18187580
-
Jegga AG, Inga A, Menendez D, Aronow BJ, Resnick MA, (2008) Functional evolution of the p53 regulatory network through its target response elements. Proc Natl Acad Sci U S A 105: 944-949. doi:10.1073/pnas.0704694105. PubMed: 18187580.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 944-949
-
-
Jegga, A.G.1
Inga, A.2
Menendez, D.3
Aronow, B.J.4
Resnick, M.A.5
-
56
-
-
84869090231
-
Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis
-
doi:10.1038/cdd.2012.89. PubMed: 22790872
-
Nikulenkov F, Spinnler C, Li H, Tonelli C, Shi Y, et al. (2012) Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis. Cell Death Differ 19: 1992-2002. doi:10.1038/cdd.2012.89. PubMed: 22790872.
-
(2012)
Cell Death Differ
, vol.19
, pp. 1992-2002
-
-
Nikulenkov, F.1
Spinnler, C.2
Li, H.3
Tonelli, C.4
Shi, Y.5
-
57
-
-
54749113722
-
The metabolism of proline as microenvironmental stress substrate
-
PubMed, -2015S-2015S
-
Phang JM, Pandhare J, Liu YM, (2008) The metabolism of proline as microenvironmental stress substrate. J Nutr 138(2008S) -2015S-2015S. PubMed: 18806116.
-
(2008)
J Nutr
, vol.138
-
-
Phang, J.M.1
Pandhare, J.2
Liu, Y.M.3
-
58
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
doi:10.1016/j.cell.2006.05.036. PubMed: 16839880
-
Bensaad K, Tsuruta A, Selak MA, Vidal MNC, Nakano K, et al. (2006) TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126: 107-120. doi:10.1016/j.cell.2006.05.036. PubMed: 16839880.
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.C.4
Nakano, K.5
-
59
-
-
33745713432
-
p53 and metabolism: Inside the TIGAR
-
doi:10.1016/j.cell.2006.06.032. PubMed: 16839873
-
Green DR, Chipuk JE, (2006) p53 and metabolism: Inside the TIGAR. Cell 126: 30-32. doi:10.1016/j.cell.2006.06.032. PubMed: 16839873.
-
(2006)
Cell
, vol.126
, pp. 30-32
-
-
Green, D.R.1
Chipuk, J.E.2
-
60
-
-
21744448805
-
Differential recognition of response elements determines target gene specificity for p53 and p63
-
doi:10.1128/MCB.25.14.6077-6089.2005. PubMed: 15988020
-
Osada M, Park HL, Nagakawa Y, Yamashita K, Fomenkov A, et al. (2005) Differential recognition of response elements determines target gene specificity for p53 and p63. Mol Cell Biol 25: 6077-6089. doi:10.1128/MCB.25.14.6077-6089.2005. PubMed: 15988020.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6077-6089
-
-
Osada, M.1
Park, H.L.2
Nagakawa, Y.3
Yamashita, K.4
Fomenkov, A.5
-
61
-
-
79955609976
-
Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements
-
doi:10.1073/pnas.1013657108. PubMed: 21464285
-
Chen C, Gorlatova N, Kelman Z, Herzberg O, (2011) Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements. Proc Natl Acad Sci U S A 108: 6456-6461. doi:10.1073/pnas.1013657108. PubMed: 21464285.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 6456-6461
-
-
Chen, C.1
Gorlatova, N.2
Kelman, Z.3
Herzberg, O.4
-
62
-
-
84863268243
-
Pliable DNA conformation of response elements bound to transcription factor p63
-
doi:10.1074/jbc.M111.315820. PubMed: 22247550
-
Chen C, Gorlatova N, Herzberg O, (2012) Pliable DNA conformation of response elements bound to transcription factor p63. J Biol Chem 287: 7477-7486. doi:10.1074/jbc.M111.315820. PubMed: 22247550.
-
(2012)
J Biol Chem
, vol.287
, pp. 7477-7486
-
-
Chen, C.1
Gorlatova, N.2
Herzberg, O.3
-
63
-
-
84859945221
-
Structure of p73 DNA-binding domain tetramer modulates p73 transactivation
-
doi:10.1073/pnas.1115463109. PubMed: 22474346
-
Ethayathulla AS, Tse PW, Monti P, Nguyen S, Inga A, et al. (2012) Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. Proc Natl Acad Sci U S A 109: 6066-6071. doi:10.1073/pnas.1115463109. PubMed: 22474346.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 6066-6071
-
-
Ethayathulla, A.S.1
Tse, P.W.2
Monti, P.3
Nguyen, S.4
Inga, A.5
-
64
-
-
33745209412
-
Structural basis of DNA recognition by p53 tetramers
-
doi:10.1016/j.molcel.2006.05.015. PubMed: 16793544
-
Kitayner M, Rozenberg H, Kessler N, Rabinovich D, Shaulov L, et al. (2006) Structural basis of DNA recognition by p53 tetramers. Mol Cell 22: 741-753. doi:10.1016/j.molcel.2006.05.015. PubMed: 16793544.
-
(2006)
Mol Cell
, vol.22
, pp. 741-753
-
-
Kitayner, M.1
Rozenberg, H.2
Kessler, N.3
Rabinovich, D.4
Shaulov, L.5
-
65
-
-
38949187278
-
Functional evolution of the p53 regulatory network through its target response elements
-
doi:10.1073/pnas.0704694105. PubMed: 18187580
-
Jegga AG, Inga A, Menendez D, Aronow BJ, Resnick MA, (2008) Functional evolution of the p53 regulatory network through its target response elements. Proc Natl Acad Sci U S A 105: 944-949. doi:10.1073/pnas.0704694105. PubMed: 18187580.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 944-949
-
-
Jegga, A.G.1
Inga, A.2
Menendez, D.3
Aronow, B.J.4
Resnick, M.A.5
-
66
-
-
17144399973
-
Comparative binding of p53 to its promoter and DNA recognition elements
-
doi:10.1016/j.jmb.2005.03.014. PubMed: 15826656
-
Weinberg RL, Veprintsev DB, Bycroft M, Fersht AR, (2005) Comparative binding of p53 to its promoter and DNA recognition elements. J Mol Biol 348: 589-596. doi:10.1016/j.jmb.2005.03.014. PubMed: 15826656.
-
(2005)
J Mol Biol
, vol.348
, pp. 589-596
-
-
Weinberg, R.L.1
Veprintsev, D.B.2
Bycroft, M.3
Fersht, A.R.4
-
67
-
-
0034881964
-
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment
-
doi:10.1016/S1097-2765(01)00283-0. PubMed: 11511360
-
Espinosa JM, Emerson BM, (2001) Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment. Mol Cell 8: 57-69. doi:10.1016/S1097-2765(01)00283-0. PubMed: 11511360.
-
(2001)
Mol Cell
, vol.8
, pp. 57-69
-
-
Espinosa, J.M.1
Emerson, B.M.2
-
68
-
-
41149090794
-
Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA
-
doi:10.1093/nar/gkm1040. PubMed: 18234719
-
Veprintsev DB, Fersht AR, (2008) Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA. Nucleic Acids Res 36: 1589-1598. doi:10.1093/nar/gkm1040. PubMed: 18234719.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1589-1598
-
-
Veprintsev, D.B.1
Fersht, A.R.2
-
69
-
-
58149478492
-
mTOR regulates autophagy-associated genes downstream of p73
-
doi:10.4161/auto.5.1.7294. PubMed: 19001857
-
Rosenbluth JM, Pietenpol JA, (2009) mTOR regulates autophagy-associated genes downstream of p73. Autophagy 5: 114-116. doi:10.4161/auto.5.1.7294. PubMed: 19001857.
-
(2009)
Autophagy
, vol.5
, pp. 114-116
-
-
Rosenbluth, J.M.1
Pietenpol, J.A.2
-
70
-
-
79952129478
-
Differential regulation of the p73 cistrome by mammalian target of rapamycin reveals transcriptional programs of mesenchymal differentiation and tumorigenesis
-
doi:10.1073/pnas.1011936108. PubMed: 21245298
-
Rosenbluth JM, Mays DJ, Jiang A, Shyr Y, Pietenpol JA, (2011) Differential regulation of the p73 cistrome by mammalian target of rapamycin reveals transcriptional programs of mesenchymal differentiation and tumorigenesis. Proc Natl Acad Sci U S A 108: 2076-2081. doi:10.1073/pnas.1011936108. PubMed: 21245298.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 2076-2081
-
-
Rosenbluth, J.M.1
Mays, D.J.2
Jiang, A.3
Shyr, Y.4
Pietenpol, J.A.5
-
71
-
-
67650087634
-
Regulation and Function of Proline Oxidase Under Nutrient Stress
-
doi:10.1002/jcb.22174. PubMed: 19415679
-
Pandhare J, Donald SP, Cooper SK, Phang JM, (2009) Regulation and Function of Proline Oxidase Under Nutrient Stress. J Cell Biochem 107: 759-768. doi:10.1002/jcb.22174. PubMed: 19415679.
-
(2009)
J Cell Biochem
, vol.107
, pp. 759-768
-
-
Pandhare, J.1
Donald, S.P.2
Cooper, S.K.3
Phang, J.M.4
-
72
-
-
84861891911
-
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC
-
PubMed: 22615405
-
Liu W, Le A, Hancock C, Lane AN, Dang CV, et al. (2012) Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC. Proc Natl Acad Sci U S A, 109: 8983-8. PubMed: 22615405.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 8983-8988
-
-
Liu, W.1
Le, A.2
Hancock, C.3
Lane, A.N.4
Dang, C.V.5
-
73
-
-
84867424108
-
Therapeutic Targeting of Myc-Reprogrammed Cancer Cell Metabolism
-
PubMed: 21960526
-
Dang CV, (2011) Therapeutic Targeting of Myc-Reprogrammed Cancer Cell Metabolism. Cold Spring Harb Symp Quant Biol, 76: 369-74. PubMed: 21960526.
-
(2011)
Cold Spring Harb Symp Quant Biol
, vol.76
, pp. 369-374
-
-
Dang, C.V.1
-
74
-
-
77952227625
-
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
-
doi:10.1073/pnas.1002459107. PubMed: 20351271
-
Suzuki S, Tanaka T, Poyurovsky MV, Nagano H, Mayama T, et al. (2010) Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species. Proc Natl Acad Sci U S A 107: 7461-7466. doi:10.1073/pnas.1002459107. PubMed: 20351271.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7461-7466
-
-
Suzuki, S.1
Tanaka, T.2
Poyurovsky, M.V.3
Nagano, H.4
Mayama, T.5
-
75
-
-
77952212178
-
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
-
doi:10.1073/pnas.1001006107. PubMed: 20378837
-
Hu W, Zhang C, Wu R, Sun Y, Levine A, et al. (2010) Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function. Proc Natl Acad Sci U S A 107: 7455-7460. doi:10.1073/pnas.1001006107. PubMed: 20378837.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7455-7460
-
-
Hu, W.1
Zhang, C.2
Wu, R.3
Sun, Y.4
Levine, A.5
|