메뉴 건너뛰기




Volumn 99, Issue 2, 2013, Pages 304-314

Regulation of cardiovascular connexins by mechanical forces and junctions

Author keywords

Cardiovascular system; Connexins; Gap junctions; Mechanotransduction

Indexed keywords

CONNEXIN 37; CONNEXIN 40; CONNEXIN 43; CONNEXIN 45; GAP JUNCTION PROTEIN; N(G) NITROARGININE METHYL ESTER; PROPIDIUM IODIDE; RENIN; TRANSCRIPTION FACTOR NRF2;

EID: 84879963293     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt095     Document Type: Review
Times cited : (42)

References (112)
  • 3
    • 79952219931 scopus 로고    scopus 로고
    • Gap junctionmediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells
    • Lim PK, Bliss SA, Patel SA, Taborga M, Dave MA, Gregory LA et al. Gap junctionmediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells. Cancer Res 2011;71:1550-1560
    • (2011) Cancer Res , vol.71 , pp. 1550-1560
    • Lim, P.K.1    Bliss, S.A.2    Patel, S.A.3    Taborga, M.4    Dave, M.A.5    Gregory, L.A.6
  • 4
    • 14544292915 scopus 로고    scopus 로고
    • Cross-presentation by intercellular peptide transfer through gap junctions
    • DOI 10.1038/nature03290
    • Neijssen J, Herberts C,DrijfhoutJW, Reits E, Janssen L, Neefjes J. Cross-presentation by intercellular peptide transfer through gap junctions. Nature 2005;434:83-88 (Pubitemid 40349389)
    • (2005) Nature , vol.434 , Issue.7029 , pp. 83-88
    • Neijssen, J.1    Herberts, C.2    Drijfhout, J.W.3    Reits, E.4    Janssen, L.5    Neefjes, J.6
  • 5
    • 0037382614 scopus 로고    scopus 로고
    • Beyond the gap: Functions of unpaired connexon channels
    • DOI 10.1038/nrm1072
    • Goodenough DA, Paul DL. Beyond the gap: Functions of unpaired connexon channels. Nat Rev Mol Cell Biol 2003;4:285-294 (Pubitemid 36383955)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.4 , pp. 285-294
    • Goodenough, D.A.1    Paul, D.L.2
  • 7
    • 0033503617 scopus 로고    scopus 로고
    • Distribution of connexin37, connexin40 and connexin43 in the aorta and coronary artery of several mammals
    • van Kempen MJ, Jongsma HJ. Distribution of connexin37, connexin40 and connexin43 in the aorta and coronary artery of several mammals. Histochem Cell Biol 1999;112: 479-486 (Pubitemid 30169598)
    • (1999) Histochemistry and Cell Biology , vol.112 , Issue.6 , pp. 479-486
    • Van Kempen, M.J.A.1    Jongsma, H.J.2
  • 8
    • 0033798039 scopus 로고    scopus 로고
    • Age-related alteration of gap junction distribution and connexin expression in rat aortic endothelium
    • Yeh HI, Chang HM, LuWW, Lee YN, Ko YS, Severs NJ et al. Age-related alteration of gap junction distribution and connexin expression in rat aortic endothelium. J Histochem Cytochem 2000;48:1377-1389
    • (2000) J Histochem Cytochem , vol.48 , pp. 1377-1389
    • Yeh, H.I.1    Chang, H.M.2    Lu, W.W.3    Lee, Y.N.4    Ko, Y.S.5    Severs, N.J.6
  • 11
    • 0037465360 scopus 로고    scopus 로고
    • Reduced connexin43 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice
    • DOI 10.1161/01.CIR.0000051364.70064.D1
    • Kwak BR, Veillard N, Pelli G, Mulhaupt F, James RW, Chanson M et al. Reduced connexin43 expression inhibits atherosclerotic lesion formation in low-Density lipoprotein receptor-Deficient mice. Circulation 2003;107:1033-1039 (Pubitemid 36258728)
    • (2003) Circulation , vol.107 , Issue.7 , pp. 1033-1039
    • Kwak, B.R.1    Veillard, N.2    Pelli, G.3    Mulhaupt, F.4    James, R.W.5    Chanson, M.6    Mach, F.7
  • 12
    • 78249264775 scopus 로고    scopus 로고
    • Loss of connexin40 is associated with decreased endothelium-Dependent relaxations and eNOS levels in the mouse aorta
    • Alonso F, Boittin FX, Beny JL, Heafliger JA. Loss of connexin40 is associated with decreased endothelium-Dependent relaxations and eNOS levels in the mouse aorta. Am J Physiol Heart Circ Physiol 2010;299:H1365-H1373
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Alonso, F.1    Boittin, F.X.2    Beny, J.L.3    Heafliger, J.A.4
  • 17
    • 84863731508 scopus 로고    scopus 로고
    • Myoendothelial contacts gap junctions, and microdomains: Anatomical links to function
    • Sandow SL, Senadheera S, Bertrand PP, Murphy TV, Tare M. Myoendothelial contacts, gap junctions, and microdomains: Anatomical links to function? Microcirculation 2012;19: 403-415
    • (2012) Microcirculation , vol.19 , pp. 403-415
    • Sandow, S.L.1    Senadheera, S.2    Bertrand, P.P.3    Murphy, T.V.4    Tare, M.5
  • 18
    • 0033956534 scopus 로고    scopus 로고
    • Incidence of myoendothelial gap junctions in the proximal and distal mesenteric arteries of the rat is suggestive of a role in endothelium-derived hyperpolarizing factor-mediated responses
    • SandowSL, Hill CE. Incidence of myoendothelial gap junctions in the proximal and distal mesenteric arteries of the rat is suggestive of a role in endothelium-Derived hyperpolarizing factor-mediated responses. Circ Res 2000;86:341-346 (Pubitemid 30108829)
    • (2000) Circulation Research , vol.86 , Issue.3 , pp. 341-346
    • Sandow, S.L.1    Hill, C.E.2
  • 19
    • 0037205263 scopus 로고    scopus 로고
    • Involvement of myoendothelial gap junctions in the actions of endothelium-derived hyperpolarizing factor
    • DOI 10.1161/01.RES.0000019756.88731.83
    • Sandow SL, Tare M, Coleman HA, Hill CE, Parkington HC. Involvement of myoendothelial gap junctions in the actions of endothelium-Derived hyperpolarizing factor. Circ Res 2002;90:1108-1113 (Pubitemid 34627910)
    • (2002) Circulation Research , vol.90 , Issue.10 , pp. 1108-1113
    • Sandow, S.L.1    Tare, M.2    Coleman, H.A.3    Hill, C.E.4    Parkington, H.C.5
  • 20
    • 69249214052 scopus 로고    scopus 로고
    • Heterogeneous expression of endothelial connexin (Cx 37, Cx40, and Cx43 in rat large veins
    • Inai T, Shibata Y. Heterogeneous expression of endothelial connexin (Cx) 37, Cx40, and Cx43 in rat large veins. Anat Sci Int 2009;84:237-245
    • (2009) Anat Sci Int , vol.84 , pp. 237-245
    • Inai, T.1    Shibata, Y.2
  • 21
    • 78650144766 scopus 로고    scopus 로고
    • Differential endothelial gap junction expression in venous vessels exposed to different hemodynamics
    • Chang CJ,WuLS, Hsu LA, Chang GJ, Chen CF, Yeh HI et al. Differential endothelial gap junction expression in venous vessels exposed to different hemodynamics. J Histochem Cytochem 2010;58:1083-1092
    • (2010) J Histochem Cytochem , vol.58 , pp. 1083-1092
    • Chang, C.J.1    Wu, L.S.2    Hsu, L.A.3    Chang, G.J.4    Chen, C.F.5    Yeh, H.I.6
  • 22
    • 79955954437 scopus 로고    scopus 로고
    • Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax
    • Kanady JD, Dellinger MT, Munger SJ, Witte MH, Simon AM. Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax. Dev Biol 2011;354:253-266
    • (2011) Dev Biol , vol.354 , pp. 253-266
    • Kanady, J.D.1    Dellinger, M.T.2    Munger, S.J.3    Witte, M.H.4    Simon, A.M.5
  • 23
    • 84857026228 scopus 로고    scopus 로고
    • Mechanotransduction, PROX1, andFOXC2cooperate to control connexin37 and calcineurin during lymphatic-valve formation
    • Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C et al. Mechanotransduction, PROX1, andFOXC2cooperate to control connexin37 and calcineurin during lymphatic-valve formation. Dev Cell 2012;22:430-445
    • (2012) Dev Cell , vol.22 , pp. 430-445
    • Sabine, A.1    Agalarov, Y.2    Maby-El Hajjami, H.3    Jaquet, M.4    Hagerling, R.5    Pollmann, C.6
  • 24
    • 84871682633 scopus 로고    scopus 로고
    • Absence of venous valves in mice lacking Connexin37
    • Munger SJ, Kanady JD, Simon AM. Absence of venous valves in mice lacking Connexin37. Dev Biol 2013;373:338-348
    • (2013) Dev Biol , vol.373 , pp. 338-348
    • Munger, S.J.1    Kanady, J.D.2    Simon, A.M.3
  • 25
    • 51749110724 scopus 로고    scopus 로고
    • Remodelling of gap junctions and connexin expression in diseased myocardium
    • Severs NJ, Bruce AF, Dupont E, Rothery S. Remodelling of gap junctions and connexin expression in diseased myocardium. Cardiovasc Res 2008;80:9-19
    • (2008) Cardiovasc Res , vol.80 , pp. 9-19
    • Severs, N.J.1    Bruce, A.F.2    Dupont, E.3    Rothery, S.4
  • 26
    • 1142297603 scopus 로고    scopus 로고
    • Gap junction-mediated spread of cell injury and death during myocardial ischemia-reperfusion
    • DOI 10.1016/j.cardiores.2003.11.039
    • Garcia-Dorado D, Rodriguez-Sinovas A, Ruiz-Meana M. Gap junction-mediated spread of cell injury and death during myocardial ischemia-reperfusion. Cardiovasc Res 2004;61: 386-401 (Pubitemid 38210146)
    • (2004) Cardiovascular Research , vol.61 , Issue.3 , pp. 386-401
    • Garcia-Dorado, D.1    Rodriguez-Sinovas, A.2    Ruiz-Meana, M.3
  • 28
    • 58049213790 scopus 로고    scopus 로고
    • Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology
    • Davies PF. Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat Clin Pract Cardiovasc Med 2009;6:16-26
    • (2009) Nat Clin Pract Cardiovasc Med , vol.6 , pp. 16-26
    • Davies, P.F.1
  • 29
    • 59649088602 scopus 로고    scopus 로고
    • Key transcriptional regulators of the vasoprotective effects of shear stress
    • Boon RA, Horrevoets AJ. Key transcriptional regulators of the vasoprotective effects of shear stress. Hamostaseologie 2009;29:39-40. 41-3
    • (2009) Hamostaseologie , vol.29 , Issue.39-40 , pp. 41-43
    • Boon, R.A.1    Horrevoets, A.J.2
  • 30
    • 78751652828 scopus 로고    scopus 로고
    • Effects of disturbed flow on vascular endothelium: Pathophysiological basis and clinical perspectives
    • Chiu JJ, Chien S. Effects of disturbed flow on vascular endothelium: Pathophysiological basis and clinical perspectives. Physiol Rev 2011;91:327-387
    • (2011) Physiol Rev , vol.91 , pp. 327-387
    • Chiu, J.J.1    Chien, S.2
  • 32
    • 80054765899 scopus 로고    scopus 로고
    • Connexins: Key mediators of endocrine function
    • Bosco D, Haefliger JA, Meda P. Connexins: Key mediators of endocrine function. Physiol Rev 2011;91:1393-1445
    • (2011) Physiol Rev , vol.91 , pp. 1393-1445
    • Bosco, D.1    Haefliger, J.A.2    Meda, P.3
  • 34
    • 0001376159 scopus 로고
    • The electrical constants of purkinje fibres
    • Weidmann S. The electrical constants of Purkinje fibres. J Physiol 1952;118:348-360
    • (1952) J Physiol , vol.118 , pp. 348-360
    • Weidmann, S.1
  • 35
    • 73349090269 scopus 로고    scopus 로고
    • Biological and biophysical properties of vascular connexin channels
    • Johnstone S, Isakson B, Locke D. Biological and biophysical properties of vascular connexin channels. Int Rev Cell Mol Biol 2009;278:69-118
    • (2009) Int Rev Cell Mol Biol , vol.278 , pp. 69-118
    • Johnstone, S.1    Isakson, B.2    Locke, D.3
  • 36
    • 0032556026 scopus 로고    scopus 로고
    • Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed
    • Gabriels JE, Paul DL. Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed. Circ Res 1998;83:636-643 (Pubitemid 28427747)
    • (1998) Circulation Research , vol.83 , Issue.6 , pp. 636-643
    • Gabriels, J.E.1    Paul, D.L.2
  • 37
    • 12944332230 scopus 로고    scopus 로고
    • Shear stress-induced upregulation of connexin 43 expression in endothelial cells on upstream surfaces of rat cardiac valves
    • DOI 10.1007/s00418-004-0717-6
    • Inai T, Mancuso MR, McDonald DM, Kobayashi J, Nakamura K, Shibata Y. Shear stress-induced upregulation of connexin 43 expression in endothelial cells on upstream surfaces of rat cardiac valves. Histochem Cell Biol 2004;122:477-483 (Pubitemid 40379017)
    • (2004) Histochemistry and Cell Biology , vol.122 , Issue.5 , pp. 477-483
    • Inai, T.1    Mancuso, M.R.2    McDonald, D.M.3    Kobayashi, J.4    Nakamura, K.5    Shibata, Y.6
  • 38
    • 0032550290 scopus 로고    scopus 로고
    • Regulation of vascular connexin43 gene expression by mechanical loads
    • Cowan DB, Lye SJ, Langille BL. Regulation of vascular connexin43 gene expression by mechanical loads. Circ Res 1998;82:786-793 (Pubitemid 28185846)
    • (1998) Circulation Research , vol.82 , Issue.7 , pp. 786-793
    • Cowan, D.B.1    Lye, S.J.2    Langille, B.L.3
  • 40
    • 33645002145 scopus 로고    scopus 로고
    • Shear stress and cyclic circumferential stretch, but not pressure, alter connexin43 expression in endothelial cells
    • Kwak BR, Silacci P, Stergiopulos N, Hayoz D, Meda P. Shear stress and cyclic circumferential stretch, but not pressure, alter connexin43 expression in endothelial cells. Cell Commun Adhes 2005; 12:261-270
    • (2005) Cell Commun Adhes , vol.12 , pp. 261-270
    • Kwak, B.R.1    Silacci, P.2    Stergiopulos, N.3    Hayoz, D.4    Meda, P.5
  • 41
    • 77955143584 scopus 로고    scopus 로고
    • An angiotensin IIand NF-kappaB-Dependent mechanism increases connexin 43 in murine arteries targeted by renin-Dependent hypertension
    • Alonso F, Krattinger N, Mazzolai L, SimonA,Waeber G, Meda P et al. An angiotensin IIand NF-kappaB-Dependent mechanism increases connexin 43 in murine arteries targeted by renin-Dependent hypertension. Cardiovasc Res 2010;87:166-176
    • (2010) Cardiovasc Res , vol.87 , pp. 166-176
    • Alonso, F.1    Krattinger, N.2    Mazzolai, L.3    Simon, A.4    Waeber, G.5    Meda, P.6
  • 43
    • 74949098727 scopus 로고    scopus 로고
    • Endothelial cell responses to atheroprone flow are driven by two separate flow components: Low time-Average shear stress and fluid flow reversal
    • Conway DE, Williams MR, Eskin SG, McIntire LV. Endothelial cell responses to atheroprone flow are driven by two separate flow components: Low time-Average shear stress and fluid flow reversal. Am J Physiol Heart Circ Physiol 2010;298:H367-H374
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Conway, D.E.1    Williams, M.R.2    Eskin, S.G.3    McIntire, L.V.4
  • 44
    • 79952339784 scopus 로고    scopus 로고
    • Transcriptional remodeling of ion channel subunits by flow adaptation in human coronary artery endothelial cells
    • Kefaloyianni E, Coetzee WA. Transcriptional remodeling of ion channel subunits by flow adaptation in human coronary artery endothelial cells. J Vasc Res 2011;48: 357-367
    • (2011) J Vasc Res , vol.48 , pp. 357-367
    • Kefaloyianni, E.1    Coetzee, W.A.2
  • 46
    • 80051924091 scopus 로고    scopus 로고
    • Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress
    • White SJ, Hayes EM, Lehoux S, Jeremy JY, Horrevoets AJ, NewbyAC.Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress. J Cell Physiol 2011;226:2841-2848
    • (2011) J Cell Physiol , vol.226 , pp. 2841-2848
    • White, S.J.1    Hayes, E.M.2    Lehoux, S.3    Jeremy, J.Y.4    Horrevoets, A.J.5    Newby, A.C.6
  • 47
  • 51
    • 77953316401 scopus 로고    scopus 로고
    • Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flowdriven arteriogenesis
    • Buschmann I, Pries A, Styp-Rekowska B, Hillmeister P, Loufrani L, HenrionD et al. Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flowdriven arteriogenesis. Development 2010;137:2187-2196
    • (2010) Development , vol.137 , pp. 2187-2196
    • Buschmann, I.1    Pries, A.2    Styp-Rekowska, B.3    Hillmeister, P.4    Loufrani, L.5    Henrion, D.6
  • 54
    • 70049112901 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of pulmonary hypertension: The task force for the diagnosis and treatment of pulmonary hypertension of the european society of cardiology (esc) and the european respiratory society (ers endorsed by the international society of heart and lung transplantation (ishlt)
    • Galie N, HoeperMM, Humbert M, Torbicki A, Vachiery JL, Barbera JA et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 2009;30: 2493-2537
    • (2009) Eur Heart J , vol.30 , pp. 2493-2537
    • Galie, N.1    Hoeper, M.M.2    Humbert, M.3    Torbicki, A.4    Vachiery, J.L.5    Barbera, J.A.6
  • 55
    • 84866926572 scopus 로고    scopus 로고
    • Pulmonary hypertension
    • Shah SJ. Pulmonary hypertension. JAMA 2012;308:1366-1374
    • (2012) JAMA , vol.308 , pp. 1366-1374
    • Shah, S.J.1
  • 60
    • 0029858756 scopus 로고    scopus 로고
    • Vascular gap junctional communication is increased in mineralocorticoid- salt hypertension
    • Watts SW, Webb RC. Vascular gap junctional communication is increased in mineralocorticoid-salt hypertension. Hypertension 1996;28:888-893 (Pubitemid 26365535)
    • (1996) Hypertension , vol.28 , Issue.5 , pp. 888-893
    • Watts, S.W.1    Webb, R.C.2
  • 61
    • 0034957254 scopus 로고    scopus 로고
    • Connexins 40 and 43 are differentially regulated within the kidneys of rats with renovascular hypertension
    • DOI 10.1046/j.1523-1755.2001.00786.x
    • Haefliger JA, Demotz S, Braissant O, Sutter E,Waeber B, Nicod P et al. Connexins 40 and 43 are differentially regulated within the kidneys of rats with renovascular hypertension. Kidney Int 2001;60:190-201 (Pubitemid 32587554)
    • (2001) Kidney International , vol.60 , Issue.1 , pp. 190-201
    • Haefliger, J.-A.1    Demotz, S.2    Braissant, O.3    Suter, E.4    Waeber, B.5    Nicod, P.6    Meda, P.7
  • 63
    • 33644807983 scopus 로고    scopus 로고
    • Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-Day carvedilol treatment
    • Yeh HI, Lee PY, Su CH, Tian TY, Ko YS, Tsai CH. Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-Day carvedilol treatment. Am J Hypertens 2006;19:129-135
    • (2006) Am J Hypertens , vol.19 , pp. 129-135
    • Yeh, H.I.1    Lee, P.Y.2    Su, C.H.3    Tian, T.Y.4    Ko, Y.S.5    Tsai, C.H.6
  • 64
    • 0036464049 scopus 로고    scopus 로고
    • Decreased endothelial size and connexin expression in rat caudal arteries during hypertension
    • DOI 10.1097/00004872-200202000-00014
    • Rummery NM, McKenzie KU, Whitworth JA, Hill CE. Decreased endothelial size and connexin expression in rat caudal arteries during hypertension. J Hypertens 2002;20: 247-253 (Pubitemid 34913789)
    • (2002) Journal of Hypertension , vol.20 , Issue.2 , pp. 247-253
    • Rummery, N.M.1    McKenzie, K.U.S.2    Whitworth, J.A.3    Hill, C.E.4
  • 65
    • 14044278193 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition restores endothelial but not medial connexin expression in hypertensive rats
    • DOI 10.1097/00004872-200502000-00014
    • Rummery NM, Grayson TH, Hill CE. Angiotensin-converting enzyme inhibition restores endothelial but not medial connexin expression in hypertensive rats. J Hypertens 2005;23:317-328 (Pubitemid 40279635)
    • (2005) Journal of Hypertension , vol.23 , Issue.2 , pp. 317-328
    • Rummery, N.M.1    Grayson, T.H.2    Hill, C.E.3
  • 67
    • 63449117719 scopus 로고    scopus 로고
    • Connexin abundance in resistance vessels from the renal microcirculation in normo-And hypertensive rats
    • Braunstein TH, Sorensen CM, Holstein-Rathlou NH. Connexin abundance in resistance vessels from the renal microcirculation in normo-And hypertensive rats. APMIS 2009;117:268-276
    • (2009) APMIS , vol.117 , pp. 268-276
    • Braunstein, T.H.1    Sorensen, C.M.2    Holstein-Rathlou, N.H.3
  • 70
    • 84870244754 scopus 로고    scopus 로고
    • Defectivecx40 maintains cx37 expression but intact cx40 is crucial for conducted dilations irrespective of hypertension
    • Jobs A, Schmidt K, Schmidt VJ, Lubkemeier I, van VeenTA, KurtzAet al. DefectiveCx40 maintains Cx37 expression but intact Cx40 is crucial for conducted dilations irrespective of hypertension. Hypertension 2012;60:1422-1429
    • (2012) Hypertension , vol.60 , pp. 1422-1429
    • Jobs, A.1    Schmidt, K.2    Schmidt, V.J.3    Lubkemeier, I.4    Van, VeenT.A.5    Kurtz, A.6
  • 71
    • 33947514231 scopus 로고    scopus 로고
    • Connexin40 is essential for the pressure control of renin synthesis and secretion
    • DOI 10.1161/01.RES.0000258856.19922.45, PII 0000301220070302000015
    • Wagner C, de Wit C, Kurtz L, Grunberger C, Kurtz A, Schweda F. Connexin40 is essential for the pressure control of renin synthesis and secretion. Circ Res 2007;100: 556-563 (Pubitemid 46673265)
    • (2007) Circulation Research , vol.100 , Issue.4 , pp. 556-563
    • Wagner, C.1    De Wit, C.2    Kurtz, L.3    Grunberger, C.4    Kurtz, A.5    Schweda, F.6
  • 74
    • 0028359886 scopus 로고
    • Molecular cloning of two human cardiac gap junction proteins, connexin40 and connexin45
    • DOI 10.1006/jmcc.1994.1103
    • Kanter HL, Saffitz JE, Beyer EC. Molecular cloning of two human cardiac gap junction proteins, connexin40 and connexin45. J Mol Cell Cardiol 1994;26:861-868 (Pubitemid 24223236)
    • (1994) Journal of Molecular and Cellular Cardiology , vol.26 , Issue.7 , pp. 861-868
    • Kanter, H.L.1    Saffizt, J.E.2    Beyer, E.C.3
  • 77
    • 0141590655 scopus 로고    scopus 로고
    • Lack of vascular connexin 40 is associated with hypertension and irregular arteriolar vasomotion
    • de Wit C, Roos F, Bolz SS, Pohl U. Lack of vascular connexin 40 is associated with hypertension and irregular arteriolar vasomotion. Physiol Genomics 2003;13:169-177 (Pubitemid 37129181)
    • (2003) Physiological Genomics , vol.13 , pp. 169-177
    • De Wit, C.1    Roos, F.2    Bolz, S.-S.3    Pohl, U.4
  • 79
    • 0344490336 scopus 로고    scopus 로고
    • Central role of connexin40 in the propagation of electrically activated vasodilation in mouse cremasteric arterioles in vivo
    • DOI 10.1161/01.RES.0000065918.90271.9A
    • Figueroa XF, Paul DL, Simon AM, Goodenough DA, Day KH, DamonDNet al. Central role of connexin40 in the propagation of electrically activated vasodilation in mouse cremasteric arterioles in vivo. Circ Res 2003;92:793-800 (Pubitemid 36457645)
    • (2003) Circulation Research , vol.92 , Issue.7 , pp. 793-800
    • Figueroa, X.F.1    Paul, D.L.2    Simon, A.M.3    Goodenough, D.A.4    Day, K.H.5    Damon, D.N.6    Duling, B.R.7
  • 80
    • 0034682933 scopus 로고    scopus 로고
    • Pulsatile stretch remodels cell-to-cell communication in cultured myocytes
    • Zhuang J, Yamada KA, Saffitz JE, Kleber AG. Pulsatile stretch remodels cell-To-cell communication in cultured myocytes. Circ Res 2000;87:316-322 (Pubitemid 30655973)
    • (2000) Circulation Research , vol.87 , Issue.4 , pp. 316-322
    • Zhuang, J.1    Yamada, K.A.2    Saffitz, J.E.3    Kleber, A.G.4
  • 81
    • 0034685023 scopus 로고    scopus 로고
    • Regulation of connexin 43 gene expression by cyclical mechanical stretch in neonatal rat cardiomyocytes
    • DOI 10.1006/bbrc.1999.1988
    • Wang TL, Tseng YZ, Chang H. Regulation of connexin 43 gene expression by cyclical mechanical stretch in neonatal rat cardiomyocytes. Biochem Biophys Res Commun 2000;267:551-557 (Pubitemid 30076836)
    • (2000) Biochemical and Biophysical Research Communications , vol.267 , Issue.2 , pp. 551-557
    • Wang, T.-L.1    Tseng, Y.-Z.2    Chang, H.3
  • 82
    • 0034969689 scopus 로고    scopus 로고
    • Angiotensin II receptor antagonist blocks the expression of connexin43 induced by cyclical mechanical stretch in cultured neonatal rat cardiac myocytes
    • DOI 10.1006/jmcc.2000.1333
    • Shyu KG, Chen CC,Wang BW, Kuan P. Angiotensin II receptor antagonist blocks the expression of connexin43 induced by cyclical mechanical stretch in cultured neonatal rat cardiac myocytes. J Mol Cell Cardiol 2001;33:691-698 (Pubitemid 32538982)
    • (2001) Journal of Molecular and Cellular Cardiology , vol.33 , Issue.4 , pp. 691-698
    • Shyu, K.-G.1    Chen, C.-C.2    Wang, B.-W.3    Kuan, P.4
  • 83
    • 0033550149 scopus 로고    scopus 로고
    • Regulation of cardiac myocyte protein turnover and myofibrillar structure in vitro by specific directions of stretch
    • Simpson DG, Majeski M, Borg TK, Terracio L. Regulation of cardiac myocyte protein turnover and myofibrillar structure in vitro by specific directions of stretch. Circ Res 1999;85:e59-e69
    • (1999) Circ Res , vol.85
    • Simpson, D.G.1    Majeski, M.2    Borg, T.K.3    Terracio, L.4
  • 84
    • 0027722248 scopus 로고
    • Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro
    • DOI 10.1016/0092-8674(93)90541-W
    • Sadoshima J, Xu Y, Slayter HS, Izumo S. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell, 1993;75:977-984 (Pubitemid 24014554)
    • (1993) Cell , vol.75 , Issue.5 , pp. 977-984
    • Sadoshima, J.-I.1    Xu, Y.2    Slayter, H.S.3    Izumo, S.4
  • 85
    • 0027521065 scopus 로고
    • Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: Potential involvement of an autocrine/paracrine mechanism
    • Sadoshima J, Izumo S. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: Potential involvement of an autocrine/paracrine mechanism. EMBO J 1993;12:1681-1692 (Pubitemid 23112823)
    • (1993) EMBO Journal , vol.12 , Issue.4 , pp. 1681-1692
    • Sadoshima, J.-I.1    Izumo, S.2
  • 86
    • 0033582310 scopus 로고    scopus 로고
    • Pulsatile stretch stimulates vascular endothelial growth factor (VEGF) secretion by cultured rat cardiac myocytes
    • DOI 10.1006/bbrc.1998.9969
    • Seko Y, Takahashi N, Shibuya M, Yazaki Y. Pulsatile stretch stimulates vascular endothelial growth factor (VEGF) secretion by cultured rat cardiac myocytes. Biochem Biophys Res Commun 1999;254:462-465 (Pubitemid 29290423)
    • (1999) Biochemical and Biophysical Research Communications , vol.254 , Issue.2 , pp. 462-465
    • Seko, Y.1    Seko, Y.2    Takahashi, N.3    Shibuya, M.4    Yazaki, Y.5
  • 87
    • 0033921695 scopus 로고    scopus 로고
    • Cyclic stretch induces the release of growth promoting factors from cultured neonatal cardiomyocytes and cardiac fibroblasts
    • Ruwhof C, vanWamel AE, Egas JM, van der L. Cyclic stretch induces the release of growth promoting factors from cultured neonatal cardiomyocytes and cardiac fibroblasts. Mol Cell Biochem 2000;208:89-98 (Pubitemid 30451459)
    • (2000) Molecular and Cellular Biochemistry , vol.208 , Issue.1-2 , pp. 89-98
    • Ruwhof, C.1    Van Wamel, A.E.T.2    Egas, J.M.3    Van Der Laarse, A.4
  • 88
    • 0037023644 scopus 로고    scopus 로고
    • Autocrine regulation of myocyte Cx43 expression by VEGF
    • DOI 10.1161/01.RES.0000014823.75393.4D
    • Pimentel RC, Yamada KA, Kleber AG, Saffitz JE. Autocrine regulation of myocyte Cx43 expression by VEGF. Circ Res, 2002;90:671-677 (Pubitemid 34640885)
    • (2002) Circulation Research , vol.90 , Issue.6 , pp. 671-677
    • Pimentel, R.C.1    Yamada, K.A.2    Kleber, A.G.3    Saffitz, J.E.4
  • 89
    • 1642315375 scopus 로고    scopus 로고
    • Effects of Mechanical Forces and Mediators of Hypertrophy on Remodeling of Gap Junctions in the Heart
    • DOI 10.1161/01.RES.0000121575.34653.50
    • Saffitz JE, Kleber AG. Effects of mechanical forces and mediators of hypertrophy on remodeling of gap junctions in the heart. Circ Res 2004;94:585-591 (Pubitemid 38387740)
    • (2004) Circulation Research , vol.94 , Issue.5 , pp. 585-591
    • Saffitz, J.E.1    Kleber, A.G.2
  • 91
    • 0026671599 scopus 로고
    • Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies
    • Meyer RA, Laird DW, Revel JP, Johnson RG. Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies. J Cell Biol 1992;119:179-189
    • (1992) J Cell Biol , vol.119 , pp. 179-189
    • Meyer, R.A.1    Laird, D.W.2    Revel, J.P.3    Johnson, R.G.4
  • 92
    • 0034724944 scopus 로고    scopus 로고
    • Remodeling of gap junctional coupling in hypertrophied right ventricles of rats with monocrotaline-induced pulmonary hypertension
    • Uzzaman M, Honjo H, Takagishi Y, Emdad L, Magee AI, Severs NJ et al. Remodeling of gap junctional coupling in hypertrophied right ventricles of rats with monocrotaline-induced pulmonary hypertension. Circ Res 2000;86:871-878. (Pubitemid 30246984)
    • (2000) Circulation Research , vol.86 , Issue.8 , pp. 871-878
    • Uzzaman, M.1    Honjo, H.2    Takagishi, Y.3    Emdad, L.4    Magee, A.I.5    Severs, N.J.6    Kodama, I.7
  • 94
    • 61949425807 scopus 로고    scopus 로고
    • Gap junction remodeling and spironolactone-Dependent reverse remodeling in the hypertrophied heart
    • QuJ, Volpicelli FM, Garcia LI, Sandeep N, Zhang J, Marquez-Rosado L et al. Gap junction remodeling and spironolactone-Dependent reverse remodeling in the hypertrophied heart. Circ Res 2009;104:365-371
    • (2009) Circ Res , vol.104 , pp. 365-371
    • QuJ Volpicelli, F.M.1    Garcia, L.I.2    Sandeep, N.3    Zhang, J.4    Marquez-Rosado, L.5
  • 95
    • 1942534677 scopus 로고    scopus 로고
    • Connexin 43 expression and distribution in compensated and decompensated cardiac hypertrophy in patients with aortic stenosis
    • DOI 10.1016/j.cardiores.2003.12.010, PII S0008636303007788
    • Kostin S, Dammer S, Hein S, KlovekornWP, Bauer EP, Schaper J. Connexin 43 expression and distribution in compensated and decompensated cardiac hypertrophy in patients with aortic stenosis. Cardiovasc Res 2004;62:426-436 (Pubitemid 38496555)
    • (2004) Cardiovascular Research , vol.62 , Issue.2 , pp. 426-436
    • Kostin, S.1    Dammer, S.2    Hein, S.3    Klovekorn, W.P.4    Bauer, E.P.5    Schaper, J.6
  • 97
  • 98
    • 79958774848 scopus 로고    scopus 로고
    • Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmias
    • Remo BF,Qu J, Volpicelli FM, Giovannone S, Shin D, Lader J et al. Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmias. Circ Res 2011; 108:1459-1466
    • (2011) Circ Res , vol.108 , pp. 1459-1466
    • Remo, B.F.1    Qu, J.2    Volpicelli, F.M.3    Giovannone, S.4    Shin, D.5    Lader, J.6
  • 99
    • 84862891843 scopus 로고    scopus 로고
    • Remodeling of mechanical junctions and of microtubule-Associated proteins accompany cardiac connexin43 lateralization
    • e6
    • Chkourko HS, Guerrero-Serna G, Lin X, Darwish N, Pohlmann JR, Cook KE et al. Remodeling of mechanical junctions and of microtubule-Associated proteins accompany cardiac connexin43 lateralization. Heart Rhythm 2012;9:1133-1140 e6
    • (2012) Heart Rhythm , vol.9 , pp. 1133-1140
    • Chkourko, H.S.1    Guerrero-Serna, G.2    Lin, X.3    Darwish, N.4    Pohlmann, J.R.5    Cook, K.E.6
  • 100
    • 34848820956 scopus 로고    scopus 로고
    • Connexin43 remodeling caused by inhibition of plakophilin-2 expression in cardiac cells
    • DOI 10.1161/CIRCRESAHA.107.154252, PII 0000301220070928000012
    • Oxford EM, Musa H, Maass K, CoombsW, Taffet SM, Delmar M. Connexin43 remodeling caused by inhibition of plakophilin-2 expression in cardiac cells. Circ Res 2007;101: 703-711 (Pubitemid 47494101)
    • (2007) Circulation Research , vol.101 , Issue.7 , pp. 703-711
    • Oxford, E.M.1    Musa, H.2    Maass, K.3    Coombs, W.4    Taffet, S.M.5    Delmar, M.6
  • 101
    • 79955397673 scopus 로고    scopus 로고
    • A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions
    • Gehmlich K, Lambiase PD, Asimaki A, Ciaccio EJ, Ehler E, Syrris P et al. A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions. Heart Rhythm 2011;8:711-718
    • (2011) Heart Rhythm , vol.8 , pp. 711-718
    • Gehmlich, K.1    Lambiase, P.D.2    Asimaki, A.3    Ciaccio, E.J.4    Ehler, E.5    Syrris, P.6
  • 102
  • 104
    • 84861211989 scopus 로고    scopus 로고
    • Lossof alphaT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia
    • Li J, Goossens S, van Hengel J,Gao E, Cheng L, TybergheinKet al. Lossof alphaT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia. J Cell Sci 2012;125(Pt 4): 1058-1067
    • (2012) J Cell Sci , vol.125 , Issue.PART4 , pp. 1058-1067
    • Li, J.1    Goossens, S.2    Van Hengel, J.3    Gao, E.4    Cheng, L.5    Tyberghein, K.6
  • 105
    • 84863230217 scopus 로고    scopus 로고
    • Loss of cadherin-binding proteins betacatenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis
    • Swope D, Cheng L, Gao E, Li J, Radice GL. Loss of cadherin-binding proteins betacatenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis. Mol Cell Biol 2012;32:1056-1067
    • (2012) Mol Cell Biol , vol.32 , pp. 1056-1067
    • Swope, D.1    Cheng, L.2    Gao, E.3    Li, J.4    Radice, G.L.5
  • 106
  • 107
    • 84879952374 scopus 로고    scopus 로고
    • Remodeling of the cardiac sodium channel, connexin 43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy
    • Noorman M, Hakim S, Kessler E, Groeneweg J, Cox MG, AsimakiAet al. Remodeling of the cardiac sodium channel, connexin 43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy. Heart Rhythm 2012.
    • (2012) Heart Rhythm
    • Noorman, M.1    Hakim, S.2    Kessler, E.3    Groeneweg, J.4    Cox, M.G.5    Asimaki, A.6
  • 109
    • 84862760898 scopus 로고    scopus 로고
    • Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study
    • Gomes J, Finlay M, Ahmed AK, Ciaccio EJ, AsimakiA, Saffitz JE et al. Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study. Eur Heart J 2012;33:1942-1953
    • (2012) Eur Heart J , vol.33 , pp. 1942-1953
    • Gomes, J.1    Finlay, M.2    Ahmed, A.K.3    Ciaccio, E.J.4    Asimaki, A.5    Saffitz, J.E.6
  • 110
    • 70349242035 scopus 로고    scopus 로고
    • Loss of plakophilin-2 expression leads to decreased sodium current and slower conduction velocity in cultured cardiac myocytes
    • Sato PY, Musa H, CoombsW, Guerrero-Serna G, Patino GA, Taffet SM et al. Loss of plakophilin-2 expression leads to decreased sodium current and slower conduction velocity in cultured cardiac myocytes. Circ Res 2009;105:523-526
    • (2009) Circ Res , vol.105 , pp. 523-526
    • Sato, P.Y.1    Musa, H.2    Coombs, W.3    Guerrero-Serna, G.4    Patino, G.A.5    Taffet, S.M.6
  • 111
    • 84859340997 scopus 로고    scopus 로고
    • Connexin43 and the regulation of intercalated disc function
    • Delmar M, Liang FX. Connexin43 and the regulation of intercalated disc function. Heart Rhythm 2012;9:835-838
    • (2012) Heart Rhythm , vol.9 , pp. 835-838
    • Delmar, M.1    Liang, F.X.2
  • 112
    • 0028828895 scopus 로고
    • The role of gap junctional communication in contractile oscillations in arteries from normotensive and hypertensive rats
    • Tsai ML,WattsSW, Loch-Caruso R,Webb RC. The role of gap junctional communication in contractile oscillations in arteries from normotensive and hypertensive rats. J Hypertens 1995;13:1123-1133
    • (1995) J Hypertens , vol.13 , pp. 1123-1133
    • Tsai, M.L.1    Watts, S.W.2    Loch-Caruso, R.3    Webb, R.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.