Distribution of connexin37, connexin40 and connexin43 in the aorta and coronary artery of several mammals

Histochemistry and Cell Biology

Volumn 112, Issue 6, 1999, Pages 479-486

  Van Kempen, Marjan J A ^a   Jongsma, Habo J ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 40; CONNEXIN 43; GAP JUNCTION PROTEIN;

ANIMAL CELL; AORTA; ARTICLE; BLOOD VESSEL WALL; CATTLE; CELL COMMUNICATION; CONTROLLED STUDY; CORONARY ARTERY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPECIES DIFFERENCE; SWINE;

ANIMALIA; BOS TAURUS; BOVINAE; MAMMALIA; SUS SCROFA;

EID: 0033503617     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004180050432     Document Type: Article

References (28)

1. Beny JL, Connat JL (1992) An electron microscopic study of smooth muscle dye coupling in the pig coronary artery. Circ Res 70:49-55
2. Beyer EC, Paul DL, Goodenough DA (1987) Connexin43: A protein from rat heart homologous to a gap junction protein from liver. J Cell Biol 105:2621-2629
3. Beyer EC, Reed KE, Westphale EM, Kanter HL, Larson DM (1992) Molecular cloning and expression of rat connexin40, a gap junction protein expressed in vascular smooth muscle. J Membr Biol 127:69-760
4. Bruzzone R, Haefliger J-A, Gimlich RL, Paul DL (1993) Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins. Mol Biol Cell 4:7-20
5. 3. J Cell Sci 109:1765-1773
6. Cowan DB, Lye SJ, Langille BL (1998) Regulation of vascular connexin43 gene expression by mechanical loads. Circ Res 82:786-793
7. Delorme B, Dahl E, Jarry-Guichard T, Briand JP, Willecke K, Gros D, Théveniau-Ruissy M (1997) Expression pattern of connexin gene products at the early developmental stages of the mouse cardiovascular system. Circ Res 81:423-437
8. Gabriels JE, Paul Dl (1998) Connexin43 is highly localized to sites of disturbed flow in aortic endothelium but connexin37 and connexin40 are more uniformly distributed. Circ Res 83:636-643
9. Gros DB, Jongsma HJ (1996) Connexins in mammalian heart function. Bioessays 18:719-730
10. Gros D, Jarry-Guichard T, Ten Velde I, De MAzière A, Kempen MJA van, Davoust J, Briand JP, Moorman AFM, Jongsma HJ (1994) Restricted distribution of connexin 40, a gap junctional protein, in mammalian heart. Circ Res 74:839-851
11. Haefliger JA, Bruzzone R, Jenkins NA, Gilbert DJ, Copeland NG, Paul DL (1992) Four novel members of the connexin family of gap junction proteins. J Biol Chem 267:2057-2064
12. Haubrich S, Schwarz H-J, Bukauskas F, Lichtenberg-Fraté H, Traub O, Weingart R, Willecke K (1996) Incompatibility of connexin 40 and 43 hemichannels in gap junctions between mammalian cells is determined by intercellular domains. Mol Biol Cell 7:1995-2006
13. Hennemann H, Suchyna T, Lichtenberg-Fraté H, Jungbluth L, Dahl E, Shwarz J, Nicholson BJ, Willecke K (1992) Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung. J Cell Biol 117:1299-1310
14. Kirchhoff S, Nelles E, Hagendorff A, Kruger O, Traub O, Willecke K (1998) Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice. Curr Biol 8:299-302
15. Ko YS, Yeh HI, Rothery S, Dupont E, Coppen SR, Severs NJ (1999a) Connexin make-up of endothelial gap junctions in the rat pulmonary artery as revealed by immunoconfocal microscopy and triple-label immunogold electron microscopy. J Histochem Cytochem 47:683-692
16. Ko YS, Yeh HI, Haw M, Dupont E, Kaba R, Plenz G, Robenek H, Severs NJ (1999b) Differential expression of connexin43 and desmin defines two subpopulations of medial smooth muscle cells in the human internal mammary artery. Arterioscler Thromb Vasc Biol 19:1669-1680
17. Larson DM, Haudenschild CC (1990) Gap junction mRNA expression by vascular wall cells. Circ Res 66:1074-1080
18. Little TL, Beyer EC, Duling BR (1995) Connexin43 and connexin40 gap junctional proteins are present in arteriolar smooth muscle and endothelium in vivo. Am J Physiol 268:H729-H739
19. Polacek D, Lal R, Violin MV, Davies PF (1993) Gap junctional communication between vascular cells: Induction of connexin43 messenger RNA in macrophage foam cells of atherosclerotic lesions. Am J Pathol 142:593-606
20. Reaume AG, De Sousa PA, Kulkarni S, Langille BL, Zhu D, Davis TC, Juenja SC, Kidder GM, Rossant J (1995) Cardiac malformation in neonatal mice lacking connexin43. Science 267:1831-1834
21. Reed KE, Westphale EM, Larson DM, Wang Z, Veenstra RD, Beyer EC (1993) Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. J Clin Invest 91:997-1004
22. Rennick RE, Connat JL, Burnstock G, Rothery S, Severs NJ, Green CR (1993) Expression of connexin43 gap junctions between cultured vascular smooth muscle cells is dependent upon phenotype. Cell Tissue Res 271:323-332
23. Simon AM, Goodenough DA, Li E, Paul DL (1997) Female infertility in mice lacking connexin37. Nature 385:525-529
24. Simon AM, Goodenough DA, Paul DL (1998) Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block. Curr Biol 8:295-298
25. Van Rijen HVM, Kempen MJA van, Analbers LJS, Rook MB, Ginneken ACG van, Gros D, Jongsma HJ (1997) Gap junctions in human umbilical cord endothelial cells contain multiple connexins. Am J Physiol 271:C117-C130
26. Willecke K, Heynkes R, Dahl E, Stutenkemper R, Henneman H, Jungbluth S, Suchyna T, Nicholson BJ (1991) Mouse connexin37: Cloning and functional expression of a gap junction gene highly expressed in lung. J Cell Biol 114:1049-1057
27. Yeh HI, Lupu F, Dupont E, Severs N (1997) Upregulation of connexin43 gap junctions between smooth muscle cells after balloon catheter injury in the rat carotid artery. Arterioscler Thromb Vasc Biol 17:3174-3184
28. Yeh HI, Rothery S, Dupont E, Coppen SR, Severs NJ (1998) Individual gap junction plaques contain multiple connexins in arterial endothelium. Circ Res 83:1248-1263