Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia

Journal of Cell Science

Volumn 125, Issue 4, 2012, Pages 1058-1067

  Li, Jifen ^a   Goossens, Steven ^b,c   van Hengel, Jolanda ^b,c   Gao, Erhe ^a   Cheng, Lan ^a   Tyberghein, Koen ^b,c   Shang, Xiying ^a   De Rycke, Riet ^b   van Roy, Frans ^b,c   Radice, Glenn L ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

Author keywords

Catenin; Adherens junction; Cardiac intercalated disc; Connexin43; Desmosome; Gap junction; Plakophilin 2

Indexed keywords

ALPHA CATENIN; ALPHA T CATENIN; GAP JUNCTION PROTEIN; NERVE CELL ADHESION MOLECULE; PROTEIN CX43; PROTEIN PKP2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DESMOSOME; FEMALE; GAP JUNCTION; GENE DELETION; GENE TARGETING; HEART MUSCLE ISCHEMIA; HEART VENTRICLE ARRHYTHMIA; IMMUNOGOLD LABELING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ADHERENS JUNCTIONS; ALPHA CATENIN; ANIMALS; ARRHYTHMIAS, CARDIAC; CADHERINS; CARDIOMYOPATHY, DILATED; CONNEXIN 43; DESMOSOMES; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; GAP JUNCTIONS; HEART VENTRICLES; MICE; MICE, KNOCKOUT; MUTATION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; PLAKOPHILINS;

ANIMALIA; MUS;

EID: 84861211989     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.098640     Document Type: Article

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