메뉴 건너뛰기




Volumn 53, Issue 2, 2012, Pages 299-309

Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells

Author keywords

Cx37; Endothelium; Gap junction; Gene expression; KLF2; Shear stress

Indexed keywords

APOLIPOPROTEIN E; CONNEXIN 37; KRUPPEL LIKE FACTOR 2; SIMVASTATIN;

EID: 84862882679     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.05.011     Document Type: Article
Times cited : (65)

References (46)
  • 1
    • 79951669207 scopus 로고    scopus 로고
    • The immune system in atherosclerosis
    • Hansson G.K., Hermansson A. The immune system in atherosclerosis. Nat Immunol 2011, 12:204-212.
    • (2011) Nat Immunol , vol.12 , pp. 204-212
    • Hansson, G.K.1    Hermansson, A.2
  • 3
    • 29844442623 scopus 로고    scopus 로고
    • Shear stress biology of the endothelium
    • Davies P.F., Spaan J.A., Krams R. Shear stress biology of the endothelium. Ann Biomed Eng 2005, 33:1714-1718.
    • (2005) Ann Biomed Eng , vol.33 , pp. 1714-1718
    • Davies, P.F.1    Spaan, J.A.2    Krams, R.3
  • 4
    • 33644914680 scopus 로고    scopus 로고
    • Molecular mechanisms of the vascular responses to haemodynamic forces
    • Lehoux S., Castier Y., Tedgui A. Molecular mechanisms of the vascular responses to haemodynamic forces. J Intern Med 2006, 259:381-392.
    • (2006) J Intern Med , vol.259 , pp. 381-392
    • Lehoux, S.1    Castier, Y.2    Tedgui, A.3
  • 5
    • 57549110006 scopus 로고    scopus 로고
    • The role of cellular adaptation to mechanical forces in atherosclerosis
    • Hahn C., Schwartz M.A. The role of cellular adaptation to mechanical forces in atherosclerosis. Arterioscler Thromb Vasc Biol 2008, 28:2101-2107.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2101-2107
    • Hahn, C.1    Schwartz, M.A.2
  • 6
    • 33745433110 scopus 로고    scopus 로고
    • Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress
    • Cheng C., Tempel D., van Haperen R., van der Baan A., Grosveld F., Daemen M.J., et al. Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Circulation 2006, 113:2744-2753.
    • (2006) Circulation , vol.113 , pp. 2744-2753
    • Cheng, C.1    Tempel, D.2    van Haperen, R.3    van der Baan, A.4    Grosveld, F.5    Daemen, M.J.6
  • 7
    • 33646685311 scopus 로고    scopus 로고
    • KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium
    • Dekker R.J., Boon R.A., Rondaij M.G., Kragt A., Volger O.L., Elderkamp Y.W., et al. KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium. Blood 2006, 107:4354-4363.
    • (2006) Blood , vol.107 , pp. 4354-4363
    • Dekker, R.J.1    Boon, R.A.2    Rondaij, M.G.3    Kragt, A.4    Volger, O.L.5    Elderkamp, Y.W.6
  • 8
    • 17344390158 scopus 로고    scopus 로고
    • Plasma membrane channels formed by connexins: their regulation and functions
    • Saez J.C., Berthoud V.M., Branes M.C., Martinez A.D., Beyer E.C. Plasma membrane channels formed by connexins: their regulation and functions. Physiol Rev 2003, 83:1359-1400.
    • (2003) Physiol Rev , vol.83 , pp. 1359-1400
    • Saez, J.C.1    Berthoud, V.M.2    Branes, M.C.3    Martinez, A.D.4    Beyer, E.C.5
  • 9
    • 0037382614 scopus 로고    scopus 로고
    • Beyond the gap: functions of unpaired connexon channels
    • Goodenough D.A., Paul D.L. Beyond the gap: functions of unpaired connexon channels. Nat Rev Mol Cell Biol 2003, 4:285-294.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 285-294
    • Goodenough, D.A.1    Paul, D.L.2
  • 11
    • 34249082403 scopus 로고    scopus 로고
    • Connexin channel permeability to cytoplasmic molecules
    • Harris A.L. Connexin channel permeability to cytoplasmic molecules. Prog Biophys Mol Biol 2007, 94:120-143.
    • (2007) Prog Biophys Mol Biol , vol.94 , pp. 120-143
    • Harris, A.L.1
  • 12
    • 34447526059 scopus 로고    scopus 로고
    • Connexin37: a potential modifier gene of inflammatory disease
    • Chanson M., Kwak B.R. Connexin37: a potential modifier gene of inflammatory disease. J Mol Med 2007, 85:787-795.
    • (2007) J Mol Med , vol.85 , pp. 787-795
    • Chanson, M.1    Kwak, B.R.2
  • 15
    • 78650144766 scopus 로고    scopus 로고
    • Differential endothelial gap junction expression in venous vessels exposed to different hemodynamics
    • Chang C.J., Wu L.S., Hsu L.A., Chang G.J., Chen C.F., Yeh H.I., et al. Differential endothelial gap junction expression in venous vessels exposed to different hemodynamics. J Histochem Cytochem 2010, 58:1083-1092.
    • (2010) J Histochem Cytochem , vol.58 , pp. 1083-1092
    • Chang, C.J.1    Wu, L.S.2    Hsu, L.A.3    Chang, G.J.4    Chen, C.F.5    Yeh, H.I.6
  • 16
    • 28444449470 scopus 로고    scopus 로고
    • Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique
    • Cheng C., van Haperen R., de Waard M., van Damme L.C., Tempel D., Hanemaaijer L., et al. Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique. Blood 2005, 106:3691-3698.
    • (2005) Blood , vol.106 , pp. 3691-3698
    • Cheng, C.1    van Haperen, R.2    de Waard, M.3    van Damme, L.C.4    Tempel, D.5    Hanemaaijer, L.6
  • 17
    • 0025063772 scopus 로고
    • Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene
    • Montesano R., Pepper M.S., Mohle-Steinlein U., Risau W., Wagner E.F., Orci L. Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene. Cell 1990, 62:435-445.
    • (1990) Cell , vol.62 , pp. 435-445
    • Montesano, R.1    Pepper, M.S.2    Mohle-Steinlein, U.3    Risau, W.4    Wagner, E.F.5    Orci, L.6
  • 19
    • 25144498154 scopus 로고    scopus 로고
    • Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes
    • Dekker R.J., van Thienen J.V., Rohlena J., de Jager S.C., Elderkamp Y.W., Seppen J., et al. Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes. Am J Pathol 2005, 167:609-618.
    • (2005) Am J Pathol , vol.167 , pp. 609-618
    • Dekker, R.J.1    van Thienen, J.V.2    Rohlena, J.3    de Jager, S.C.4    Elderkamp, Y.W.5    Seppen, J.6
  • 20
    • 0035168133 scopus 로고    scopus 로고
    • Inhibition of endothelial wound repair by dominant negative connexin inhibitors
    • Kwak B.R., Pepper M.S., Gros D.B., Meda P. Inhibition of endothelial wound repair by dominant negative connexin inhibitors. Mol Biol Cell 2001, 12:831-845.
    • (2001) Mol Biol Cell , vol.12 , pp. 831-845
    • Kwak, B.R.1    Pepper, M.S.2    Gros, D.B.3    Meda, P.4
  • 21
    • 0021966255 scopus 로고
    • Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress
    • Ku D.N., Giddens D.P., Zarins C.K., Glagov S. Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress. Arteriosclerosis 1985, 5:293-302.
    • (1985) Arteriosclerosis , vol.5 , pp. 293-302
    • Ku, D.N.1    Giddens, D.P.2    Zarins, C.K.3    Glagov, S.4
  • 22
    • 2542500709 scopus 로고    scopus 로고
    • KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation
    • SenBanerjee S., Lin Z., Atkins G.B., Greif D.M., Rao R.M., Kumar A., et al. KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation. J Exp Med 2004, 199:1305-1315.
    • (2004) J Exp Med , vol.199 , pp. 1305-1315
    • SenBanerjee, S.1    Lin, Z.2    Atkins, G.B.3    Greif, D.M.4    Rao, R.M.5    Kumar, A.6
  • 24
    • 23244457776 scopus 로고    scopus 로고
    • Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells
    • Sen-Banerjee S., Mir S., Lin Z., Hamik A., Atkins G.B., Das H., et al. Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells. Circulation 2005, 112:720-726.
    • (2005) Circulation , vol.112 , pp. 720-726
    • Sen-Banerjee, S.1    Mir, S.2    Lin, Z.3    Hamik, A.4    Atkins, G.B.5    Das, H.6
  • 25
    • 33749426332 scopus 로고    scopus 로고
    • Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization
    • van Thienen J.V., Fledderus J.O., Dekker R.J., Rohlena J., van Ijzendoorn G.A., Kootstra N.A., et al. Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization. Cardiovasc Res 2006, 72:231-240.
    • (2006) Cardiovasc Res , vol.72 , pp. 231-240
    • van Thienen, J.V.1    Fledderus, J.O.2    Dekker, R.J.3    Rohlena, J.4    van Ijzendoorn, G.A.5    Kootstra, N.A.6
  • 26
    • 0028915946 scopus 로고
    • Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells
    • Elfgang C., Eckert R., Lichtenberg-Frate H., Butterweck A., Traub O., Klein R.A., et al. Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells. J Cell Biol 1995, 129:805-817.
    • (1995) J Cell Biol , vol.129 , pp. 805-817
    • Elfgang, C.1    Eckert, R.2    Lichtenberg-Frate, H.3    Butterweck, A.4    Traub, O.5    Klein, R.A.6
  • 27
    • 78149237287 scopus 로고    scopus 로고
    • Unexpected role for the human Cx37 C1019T polymorphism in tumour cell proliferation
    • Morel S., Burnier L., Roatti A., Chassot A., Roth I., Sutter E., et al. Unexpected role for the human Cx37 C1019T polymorphism in tumour cell proliferation. Carcinogenesis 2010, 31:1922-1931.
    • (2010) Carcinogenesis , vol.31 , pp. 1922-1931
    • Morel, S.1    Burnier, L.2    Roatti, A.3    Chassot, A.4    Roth, I.5    Sutter, E.6
  • 28
    • 57349120207 scopus 로고    scopus 로고
    • Connexin 37 profoundly slows cell cycle progression in rat insulinoma cells
    • Burt J.M., Nelson T.K., Simon A.M., Fang J.S. Connexin 37 profoundly slows cell cycle progression in rat insulinoma cells. Am J Physiol Cell Physiol 2008, 295:C1103-C1112.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Burt, J.M.1    Nelson, T.K.2    Simon, A.M.3    Fang, J.S.4
  • 29
    • 23844518937 scopus 로고    scopus 로고
    • Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2
    • Bhattacharya R., Senbanerjee S., Lin Z., Mir S., Hamik A., Wang P., et al. Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2. J Biol Chem 2005, 280:28848-28851.
    • (2005) J Biol Chem , vol.280 , pp. 28848-28851
    • Bhattacharya, R.1    Senbanerjee, S.2    Lin, Z.3    Mir, S.4    Hamik, A.5    Wang, P.6
  • 30
    • 0032556026 scopus 로고    scopus 로고
    • Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed
    • Gabriels J.E., Paul D.L. Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed. Circ Res 1998, 83:636-643.
    • (1998) Circ Res , vol.83 , pp. 636-643
    • Gabriels, J.E.1    Paul, D.L.2
  • 31
    • 0032550290 scopus 로고    scopus 로고
    • Regulation of vascular connexin43 gene expression by mechanical loads
    • Cowan D.B., Lye S.J., Langille B.L. Regulation of vascular connexin43 gene expression by mechanical loads. Circ Res 1998, 82:786-793.
    • (1998) Circ Res , vol.82 , pp. 786-793
    • Cowan, D.B.1    Lye, S.J.2    Langille, B.L.3
  • 32
    • 0033026830 scopus 로고    scopus 로고
    • Spatial and temporal regulation of gap junction connexin43 in vascular endothelial cells exposed to controlled disturbed flows in vitro
    • DePaola N., Davies P.F., Pritchard W.F., Florez L., Harbeck N., Polacek D.C. Spatial and temporal regulation of gap junction connexin43 in vascular endothelial cells exposed to controlled disturbed flows in vitro. Proc Natl Acad Sci U S A 1999, 96:3154-3159.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 3154-3159
    • DePaola, N.1    Davies, P.F.2    Pritchard, W.F.3    Florez, L.4    Harbeck, N.5    Polacek, D.C.6
  • 33
    • 33645002145 scopus 로고    scopus 로고
    • Shear stress and cyclic circumferential stretch, but not pressure, alter connexin43 expression in endothelial cells
    • Kwak B.R., Silacci P., Stergiopulos N., Hayoz D., Meda P. Shear stress and cyclic circumferential stretch, but not pressure, alter connexin43 expression in endothelial cells. Cell Commun Adhes 2005, 12:261-270.
    • (2005) Cell Commun Adhes , vol.12 , pp. 261-270
    • Kwak, B.R.1    Silacci, P.2    Stergiopulos, N.3    Hayoz, D.4    Meda, P.5
  • 34
    • 79952339784 scopus 로고    scopus 로고
    • Transcriptional remodeling of ion channel subunits by flow adaptation in human coronary artery endothelial cells
    • Kefaloyianni E., Coetzee W.A. Transcriptional remodeling of ion channel subunits by flow adaptation in human coronary artery endothelial cells. J Vasc Res 2011, 48:357-367.
    • (2011) J Vasc Res , vol.48 , pp. 357-367
    • Kefaloyianni, E.1    Coetzee, W.A.2
  • 35
    • 80051924091 scopus 로고    scopus 로고
    • Characterisation of the differential response of endothelial cells exposed to normal and elevated laminar shear stress
    • White S.J., Hayes E.M., Lehoux S., Jeremy J.Y., Horrevoets A.J., Newby A.C. Characterisation of the differential response of endothelial cells exposed to normal and elevated laminar shear stress. J Cell Physiol 2011, 226:2841-2848.
    • (2011) J Cell Physiol , vol.226 , pp. 2841-2848
    • White, S.J.1    Hayes, E.M.2    Lehoux, S.3    Jeremy, J.Y.4    Horrevoets, A.J.5    Newby, A.C.6
  • 36
    • 74949098727 scopus 로고    scopus 로고
    • Endothelial cell responses to atheroprone flow are driven by two separate flow components: low time-average shear stress and fluid flow reversal
    • Conway D.E., Williams M.R., Eskin S.G., McIntire L.V. Endothelial cell responses to atheroprone flow are driven by two separate flow components: low time-average shear stress and fluid flow reversal. Am J Physiol Heart Circ Physiol 2010, 298:H367-H374.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Conway, D.E.1    Williams, M.R.2    Eskin, S.G.3    McIntire, L.V.4
  • 37
    • 10744233033 scopus 로고    scopus 로고
    • Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta
    • Passerini A.G., Polacek D.C., Shi C., Francesco N.M., Manduchi E., Grant G.R., et al. Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta. Proc Natl Acad Sci U S A 2004, 101:2482-2487.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2482-2487
    • Passerini, A.G.1    Polacek, D.C.2    Shi, C.3    Francesco, N.M.4    Manduchi, E.5    Grant, G.R.6
  • 38
    • 35148873636 scopus 로고    scopus 로고
    • Endothelial connexin 37, connexin 40, and connexin 43 respond uniquely to substrate and shear stress
    • Johnson T.L., Nerem R.M. Endothelial connexin 37, connexin 40, and connexin 43 respond uniquely to substrate and shear stress. Endothelium 2007, 14:215-226.
    • (2007) Endothelium , vol.14 , pp. 215-226
    • Johnson, T.L.1    Nerem, R.M.2
  • 39
    • 33646406552 scopus 로고    scopus 로고
    • Flow regulates intercellular communication in HAEC by assembling functional Cx40 and Cx37 gap junctional channels
    • Ebong E.E., Kim S., DePaola N. Flow regulates intercellular communication in HAEC by assembling functional Cx40 and Cx37 gap junctional channels. Am J Physiol Heart Circ Physiol 2006, 290:H2015-H2023.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Ebong, E.E.1    Kim, S.2    DePaola, N.3
  • 40
    • 34248350010 scopus 로고    scopus 로고
    • Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2
    • Fledderus J.O., van Thienen J.V., Boon R.A., Dekker R.J., Rohlena J., Volger O.L., et al. Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2. Blood 2007, 109:4249-4257.
    • (2007) Blood , vol.109 , pp. 4249-4257
    • Fledderus, J.O.1    van Thienen, J.V.2    Boon, R.A.3    Dekker, R.J.4    Rohlena, J.5    Volger, O.L.6
  • 41
    • 77950626285 scopus 로고    scopus 로고
    • KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium
    • Boon R.A., Leyen T.A., Fontijn R.D., Fledderus J.O., Baggen J.M., Volger O.L., et al. KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium. Blood 2010, 115:2533-2542.
    • (2010) Blood , vol.115 , pp. 2533-2542
    • Boon, R.A.1    Leyen, T.A.2    Fontijn, R.D.3    Fledderus, J.O.4    Baggen, J.M.5    Volger, O.L.6
  • 44
  • 45
    • 0034037228 scopus 로고    scopus 로고
    • Heterogeneity of [Ca(2+)](i) signaling in intact rat aortic endothelium
    • Huang T.Y., Chu T.F., Chen H.I., Jen C.J. Heterogeneity of [Ca(2+)](i) signaling in intact rat aortic endothelium. FASEB J 2000, 14:797-804.
    • (2000) FASEB J , vol.14 , pp. 797-804
    • Huang, T.Y.1    Chu, T.F.2    Chen, H.I.3    Jen, C.J.4
  • 46
    • 74549136229 scopus 로고    scopus 로고
    • Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion
    • Chadjichristos C.E., Scheckenbach K.E., van Veen T.A., Richani Sarieddine M.Z., de Wit C., Yang Z., et al. Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion. Circulation 2010, 121:123-131.
    • (2010) Circulation , vol.121 , pp. 123-131
    • Chadjichristos, C.E.1    Scheckenbach, K.E.2    van Veen, T.A.3    Richani Sarieddine, M.Z.4    de Wit, C.5    Yang, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.