Age-related changes in the phospholipase d-dependent signal pathway of insulin in the rat neocortex

Neurophysiology

Volumn 45, Issue 2, 2013, Pages 120-127

  Babenko, N A ^a   Kharchenko, V S ^a  

^a V N KARAZIN KHARKIV NATIONAL UNIVERSITY   (Ukraine)

Author keywords

aging; ceramide; diaphragm; insulin; neocortex; phospholipase D

Indexed keywords

ALCOHOL; CERAMIDE; FATTY ACID; INSULIN; PALMITIC ACID; PHOSPHOLIPASE D;

AGING; ANIMAL TISSUE; ARTICLE; NEOCORTEX; NONHUMAN; RAT;

EID: 84879924299     PISSN: 00902977     EISSN: 15739007     Source Type: Journal    
DOI: 10.1007/s11062-013-9346-9     Document Type: Article

References (56)

1. K. H. Lee, A. S. Calikoglu, P. Ye, and A. J. D'Ercole, "Insulin-like growth factor-I (IGF-I) ameliorates and IGF binding protein-1 (IGFBP-1) exacerbates the effects of undernutrition on brain growth during early postnatal life: studies in IGF-I and IGFBP-1 transgenic mice," Pediat. Res., 45, No. 3, 331-336 (1999).
2. C. R. Plata-Salamán, "Insulin in the cerebrospinal fluid," Neurosci. Biobehav. Rev., 15, No. 2, 243-258 (1991).
3. Y. Yu, A. Kastin, and W. Pan, "Reciprocal interactions of insulin and insulin-like growth factor I in receptormediated transport across the blood-brain barrier," Endocrinology, 147, 2611-2615 (2006).
4. Z. Laron, "Insulin and the brain," Arch. Physiol. Biochem., 115, No. 2, 112-116 (2009).
5. W. Zhao, H. Chen, H. Xu, et al., "Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats," J. Biol. Chem., 274, No. 49, 34893-34902 (1999).
6. R. Schechter, T. Yanovitch, M. Abboud, et al., "Effects of brain endogenous insulin on neurofilament and MAPK in fetal rat neuron cell cultures," Brain Res., 808, No. 2, 270-278 (1998).
7. J. Havrankova, J. Roth, and M. Brownstein, "Insulin receptors are widely distributed in the central nervous system of the rat," Nature, 272, No. 5656, 827-829 (1978).
8. M. Salkovic-Petrisic and S. Hoyer, "Central insulin resistance as a trigger for sporadic Alzheimer-like pathology: an experimental approach," J. Neural. Transm., Suppl., No. 72, 217-233 (2007).
9. S. M. de la Monte and J. R. Wands, "Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease," J. Alzheimers Dis., 7, No. 1, 45-61 (2005).
10. S. M. de la Monte, "Insulin resistance and Alzheimer's disease," Biochem. Mol. Biol. Rep., 42, No. 8, 475-481 (2009).
11. S. Cockcroft, "Signalling roles of mammalian phospholipase D1 and D2," Cell. Mol. Life Sci., 58, No. 11, 1674-1687 (2001).
12. J. H. Exton, "Phospholipase D - structure, regulation and function," Rev. Physiol. Biochem. Pharmacol., 144, 1-94 (2002).
13. G. M. Jenkins and M. A. Frohman, "Phospholipase D: a lipid centric review," Cell. Mol. Life Sci., 62, Nos. 19/20, 2305-2316 (2005).
14. J. Klein, V. Chalifa, M. Liscovitch, and K. Löffelholz, "Role of phospholipase D activation in nervous system physiology and pathophysiology," J. Neurochem., 65, No. 4, 1445-1455 (1995).
15. G. A. Salvador, S. J. Pasquare, M. G. Ilincheta de Boschero, and N. M. Giusto, "Differential modulation of phospholipase D and phosphatidate phosphohydrolase during aging in rat cerebral cortex synaptosomes" Exp. Gerontol., 37, No. 4, 543-552 (2002).
16. T. G. Oliveira and G. Di Paolo, "Phospholipase D in brain function and Alzheimer's disease," Biochim. Biophys. Acta, 1801, No. 8, 799-805 (2010).
17. Y. Kanaho, Y. Funakoshi, and H. Hasegawa, "Phospholipase D signalling and its involvement in neurite outgrowth," Biochim. Biophys. Acta, 1791, No. 9, 898-904 (2009).
18. D. Zhao, M. A. Frohman, and J. K. Blusztajn, "Generation of choline for acetylcholine synthesis by phospholipase D isoforms," BMC (BioMed. Central) Neurosci., 2, 16 (2001).
19. N. A. Babenko and V. S. Kharchenko, "Role of ceramides in dysfunction of insulin signaling in the rat diaphragm under in vivo and in vitro condiitons", Probl. Endokrin. Pathol., No. 1, 37-43 (2009).
20. N. A. Babenko and V. S. Kharchenko, "Ceramides inhibit phospholipase D-dependent insulin signaling in liver cells of old rats," Biochemistry, 77, No. 2, 180-186 (2012).
21. Y. A. Hannun and L. M. Obeid, "Principles of bioactive lipid signalling: lessons from sphingolipids," Nat. Rev. Mol. Cell. Biol., 9, No. 2, 139-150 (2008).
22. N. A. Babenko and Y. A. Semenova, "Effects of long-term fish oil-enriched diet on the sphingolipid metabolism in brain of old rats," Exp. Gerontol., 45, No. 5, 375-380 (2010).
23. S. M. de la Monte, M. Tong, V. Nguyen, et al., "Ceramide-mediated insulin resistance and impairment of cognitive-motor functions," J. Alzheimers Dis., 21, No. 3, 967-984 (2010).
24. S. M. de la Monte, E. Re, L. Longato, and M. Tong, "Dysfunctional pro-ceramide, ER stress, and insulin/IGF signaling networks with progression of Alzheimer's disease," J. Alzheimers Dis., 30, Suppl. 2, S217-S229 (2012).
25. K. Lieb, B. L. Fiebich, M. Berger, et al., "The neuropeptide substance P activates transcription factor NF-kappa B and kappa B-dependent gene expression in human astrocytoma cells," J. Immunol., 159, 4952-4958 (1997).
26. K. Pahan, F. G. Sheikh, M. Khan, et al., "Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes," J. Biol. Chem., 273, No. 5, 2591-2600 (1998).
27. T. Wei, C. Chen, J. Hou, et al., "Nitric oxide induces oxidative stress and apoptosis in neuronal cells," Biochim. Biophys. Acta, 1498, No. 1, 72-79 (2000).
28. A. Szutowicz and W. Lysiak, "Regional and subcellular distribution of ATP-citrate lyase and other enzymes of acetyl-CoA metabolism in rat brain," J Neurochem., 35, No. 4, 775-785 (1980).
29. K. Ayasolla, M. Khan, A. K. Singh, and I. Singh, "Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E," Free Radical. Biol. Med., 37, No. 3, 325-338 (2004).
30. J. Klein, "Functions and pathophysiological roles of phospholipase D in the brain," J. Neurochem., 94, No. 6, 1473-1487 (2005).
31. S. Yoshimura, H. Sakai, K. Ohguchi, et al., "Changes in the activity and mRNA levels of phospholipase D during ceramide-induced apoptosis in rat C6 glial cells," J. Neurochem., 69, No. 2, 713-720 (1997).
32. B. Schatter, S. Jin, K. Löffelholz, and J. Klein, "Crosstalk between phosphatidic acid and ceramide during ethanol-induced apoptosis in astrocytes," BMC (BioMed. Central) Pharmacol., 5, 3 (2005).
33. J. A. Chavez, W. L. Holland, J. Bar, et al., "Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling," J. Biol. Chem., 280, No. 20, 20148-20153 (2005).
34. G. L. Moehren, J. B. Gustavsson, and J. B. Hoek "Activation and desensitization of phospholipase D in intact rat hepatocytes," J. Biol. Chem., 269, No. 2, 838-848 (1994).
35. P. Huang, Y. M. Altshuller, J. C. Hou, et al., "Insulinstimulated plasma membrane fusion of Glut4 glucose transporter-containing vesicles is regulated by phospholipase D1," Mol. Biol. Cell, 16, No. 6, 2614-2623 (2005).
36. E. G. Bligh and W. J. Dyer, "A rapid method of total lipid extraction and purification," Can. J. Biochem. Physiol., 37, No. 8, 911-917 (1959).
37. J. B. March and D. B. Weinstein, "Simple charring method for determination of lipids," J. Lipid Res., 7, No. 4, 574-580 (1966).
38. G. R. Bartlett, "Phosphorus assay in column chromatography," J. Biol. Chem., 234, No. 3, 466-468 (1959).
39. C. J. Lauter and E. G. Trams, "A spectrophotometric determination of sphingosine," J. Lipid Res., 3, 136-138 (1962).
40. O. N. Lowry, N. J. Rosebrough, A. L. Farr, and R. J. Randal, "Protein measurement with the Folin phenol reagent," J. Biol. Chem., 193, 365-375 (1951).
41. M. G. Roth, "Molecular mechanisms of PLD function in membrane traffic," Traffic, 9, No. 8, 1233-1239 (2008).
42. Y. Humeau, N. Vitale, S. Chasserot-Golaz, et al., "A role for phospholipase D1 in neurotransmitter release," Proc. Natl. Acad. Sci. USA, 98, No. 26, 15300-15305 (2001).
43. E. Sarri, I. Böckmann, U. Kempter, et al., "Regulation of phospholipase D activity in synaptosomes permeabilized with Staphylococcus aureus alpha-toxin," FEBS Lett., 440, No. 3, 287-290 (1998).
44. M. Scarselli and J. G. Donaldson, "Constitutive internalization of G protein-coupled receptors and G proteins via clathrin-independent endocytosis," J. Biol. Chem., 284, No. 6, 3577-3585 (2009).
45. M. S. Yoon, C. Yon, S. Y. Park, et al., "Role of phospholipase D1 in neurite outgrowth of neural stem cells," Biochem. Biophys. Res. Commun., 329, No. 3, 804-811 (2005).
46. M. Czarny, Y. Lavie, G. Fiucci, and M. Liscovitch, "Localization of phospholipase D in detergent-insoluble, caveolin-rich membrane domains. Modulation by caveolin-1 expression and caveolin-182-101," J. Biol. Chem., 274, No. 5, 2717-2724 (1999).
47. G. Du, Y. M. Altshuller, N. Vitale, et al., "Regulation of phospholipase D1 subcellular cycling through coordination of multiple membrane association motifs," J. Cell Biol., 162, No. 2, 305-315 (2003).
48. L. J. Pike, "Growth factor receptors, lipid rafts and caveolae: an evolving story," Biochim. Biophys. Acta, 1746, No. 3, 260-273 (2005).
49. X. Han, S. Rozen, S. H. Boyle, et al., "Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics," PLoS One, 6, No. 7, e21643 (2011).
50. L. Kh. M. Khassunekh, Ya. O. Semenova, O. A. Krasil'nikova, and N. A. Babenko, "Age-related peculiarities of the content of signal lipids in the liver and brain of rats," Fiziol. Zh., 52, No. 6, 79-84 (2006).
51. A. Abousalham, C. Liossis, L. O'Brien, and D. N. Brindley, "Cell-permeable ceramides prevent the activation of phospholipase D by ADP-ribosylation factor and RhoA," J. Biol. Chem., 272, 1069-1075 (1997).
52. A. Gidwani, H. A. Brown, D. Holowka, and B. Baird, "Disruption of lipid order by short-chain ceramides correlates with inhibition of phospholipase D and downstream signaling by FcepsilonRI," J. Cell Sci., 116, 3177-3187 (2003).
53. S. Mebarek, H. Komati, F. Naro, et al., "Inhibition of de novo ceramide synthesis upregulates phospholipase D and enhances myogenic differentiation," J. Cell Sci., 120, Part 3, 407-416 (2007).
54. I. N. Singh, L. M. Stromberg, S. G. Bourgoin, et al., "Ceramide inhibition of mammalian phospholipase D1 and D2 activities is antagonized by phosphatidyl inositol 4,5-bisphosphate," Biochemistry, 40, 11227-11233 (2001).
55. S. Patil, D. Balu, J. Melrose, and C. Chan, "Brain-regionspecificity of palmitic acid-induced abnormalities associated with Alzheimer's disease," BMC (BioMed Central) Res. Notes, 4, 1-20 (2008).
56. N. D. Ridgway and D. L. Merriam, "Metabolism of short-chain ceramide and dihydroceramide analogues in Chinese hamster ovary (CHO) cells," Biochim. Biophys. Acta, 1256, No. 1, 57-70 (1995).