Reciprocal interactions of insulin and insulin-like growth factor I in receptor-mediated transport across the blood-brain barrier

Endocrinology

Volumn 147, Issue 6, 2006, Pages 2611-2615

  Yu, Yongmei ^a   Kastin, Abba J ^a   Pan, Weihong ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN I 125; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN MICROCIRCULATION; BRAIN PERFUSION; CELL SURFACE; CONTROLLED STUDY; ENDOCYTOSIS; IN SITU HYBRIDIZATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CELLS, CULTURED; ENDOCYTOSIS; ENDOTHELIAL CELLS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; IODINE RADIOISOTOPES; MALE; MICE; NIH 3T3 CELLS; RATS; RECEPTOR, INSULIN;

EID: 33646793301     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0020     Document Type: Article

References (32)

1. Banks WA, Jaspan JB, Kastin AJ 1997 Effect of diabetes mellitus on the permeability of the blood-brain barrier to insulin. Peptides 18:1577-1584
2. Laron Z 2001 Insulin-like growth factor 1 (IGF-1): a growth hormone. Mol Pathol 54:311-316
3. Jessett DM, Rampton CS 1975 The incidence of antibody to infectious bovine rhinotracheitis virus in Kenyan cattle. Res Vet Sci 18:225-226
4. Nitert MD, Chisalita SI, Olsson K, Bornfeldt KE, Arnqvist HJ 2005 IGF-I/insulin hybrid receptors in human endothelial cells. Mol Cell Endocrinol 229:31-37
5. Klammt J, Garten A, Barnikol-Oettler A, Beck-Sickinger AG, Kiess W 2005 Comparative analysis of the signaling capabilities of the insulin receptor-related receptor. Biochem Biophys Res Commun 327:557-564
6. Reaven G 2003 Insulin resistance, hypertension, and coronary heart disease. J Clin Hypertens (Greenwich) 5:269-274
7. Sesti G, Sciacqua A, Cardellini M, Marini MA, Maio R, Vatrano M, Succurro E, Lauro R, Federici M, Perticone F 2005 Plasma concentration of IGF-I is independently associated with insulin sensitivity in subjects with different degrees of glucose tolerance. Diabetes Care 28:120-125
8. Banks WA 2004 The source of cerebral insulin. Eur J Pharmacol 490:5-12
9. Daftary SS, Gore AC 2005 IGF-1 in the brain as a regulator of reproductive neuroendocrine function. Exp Biol Med 230:292-306
10. Margolis RU, Altszuler N 1967 Insulin in the cerebrospinal fluid. Nature 215:1375-1376
11. Woods SC, Porte Jr D 1977 Relationship between plasma and cerebrospinal fluid insulin levels of dogs. Am J Physiol 233:E331-E334
12. Schwartz MW, Figlewicz DP, Baskin DG, Woods SC, Porte Jr D 1992 Insulin in the brain: a hormonal regulator of energy balance. Endocr Rev 13:387-414
13. Woods SC, Seeley RJ, Baskin DG, Schwartz MW 2003 Insulin and the bloodbrain barrier. Curr Pharm Des 9:795-800
14. Baura GD, Foster DM, Porte Jr D, Kahn SE, Bergman RN, Cobelli C, Schwartz MW 1993 Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. J Clin Invest 92:1824-1830
15. Pardridge WM, Kang YS, Buciak JL, Yang J 1995 Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate. Pharm Res 12:807-816
16. Banks WA, Jaspan JB, Huang W, Kastin AJ 1997 Transport of insulin across the blood-brain barrier: saturability at euglycemic doses of insulin. Peptides 18:1423-1429
17. Banks WA, Jaspan JB, Kastin AJ 1997 Selective, physiological transport of insulin across the blood-brain barrier: novel demonstration by species-specific radioimmunoassays. Peptides 18:1257-1262
18. Banks WA, Kastin AJ 1998 Differential permeability of the blood-brain barrier to two pancreatic peptides: insulin and amylin. Peptides 19:883-889
19. Banks WA, Kastin AJ, Pan W 1999 Uptake and degradation of blood-borne insulin by the olfactory bulb. Peptides 20:373-378
20. Duffy KR, Pardridge WM, Rosenfeld RG 1988 Human blood-brain-barrier insulin-like growth-factor receptor. Metab Clin Exp 37:136-140
21. Pan W, Kastin AJ 2000 Interactions of IGF-1 with the blood-brain barrier in vivo and in situ. Neuroendocrinology 72:171-178
22. Rosenfeld RG, Pham H, Keller BT, Borchardt RT, Pardridge WM 1987 Demonstration and structural comparison of receptors for insulin-like growth factor-I and factor-Ii (Igf-I and Igf-Ii) in brain and blood-brain-barrier. Biochem Biophys Res Commun 149:159-166
23. Vicent D, Ilany J, Kondo T, Naruse K, Fisher SJ, Kisanuki YY, Bursell S, Yanagisawa M, King GL, Kahn CR 2003 The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance. J Clin Invest 111:1373-1380
24. Kondo T, Kahn CR 2004 Altered insulin signaling in retinal tissue in diabetic states. J Biol Chem 279:37997-38006
25. Pan W, Yu Y, Cain CM, Nyberg F, Couraud PO, Kastin AJ 2005 Permeation of growth hormone across the blood-brain barrier. Endocrinology 146:4898-4904
26. Blasberg RG, Fenstermacher JD, Patlak CS 1983 Transport of α-aminoisobutyric acid across brain capillary and cellular membranes. J Cereb Blood Flow Metab 3:8-32
27. Patlak CS, Blasberg RG, Fenstermacher JD 1983 Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 3:1-7
28. Kastin AJ, Akerstrom V, Pan W 2001 Validity of multiple-time regression analysis in measurement of tritiated and iodinated leptin crossing the blood-brain barrier: meaningful controls. Peptides 22:2127-2136
29. Zlokovic BV, Hyman S, McComb JG, Lipovac MN, Tang G, Davson H 1990 Kinetics of arginine-vasopressin uptake at the blood-brain barrier. Biochim Biophys Acta 1025:191-198
30. Pan W, Banks WA, Fasold MB, Bluth J, Kastin AJ 1998 Transport of brain+derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 37:1553-1561
31. Banks WA, Kastin AJ 1985 Permeability of the blood-brain barrier to neuropeptides: the case for penetration. Psychoneuroendocrinology 10:385-399
32. Zeng G, Quon MJ 1996 Insulin-stimulated production of nitric oxide is inhibited by wortmannin: direct measurement in vascular endothelial cells. J Clin Invest 98:894-898