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Volumn 29, Issue 13, 2013, Pages

Hard-wired heterogeneity in blood stem cells revealed using a dynamic regulatory network model

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EID: 84879923473     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btt243     Document Type: Conference Paper
Times cited : (62)

References (62)
  • 1
    • 0032582512 scopus 로고    scopus 로고
    • Transcriptional regulation of the stem cell leukemia gene by PU.1 and Elf-1
    • Bockamp, E.O. et al. (1998) Transcriptional regulation of the stem cell leukemia gene by PU.1 and Elf-1. J. Biol. Chem., 273, 29032-29042.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29032-29042
    • Bockamp, E.O.1
  • 2
    • 68549085469 scopus 로고    scopus 로고
    • Executing multicellular differentiation: Quantitative predictive modelling of C.elegans vulval development
    • Bonzanni, N. et al. (2009) Executing multicellular differentiation: Quantitative predictive modelling of C.elegans vulval development. Bioinformatics, 25, 2049-2056.
    • (2009) Bioinformatics , vol.25 , pp. 2049-2056
    • Bonzanni, N.1
  • 3
    • 70649106320 scopus 로고    scopus 로고
    • In: FM 2009: Formal Methods, Lecture Notes in Computer Science., Berlin/Heidelberg Springer
    • Bonzanni, N. et al. (2009) What can formal methods bring to systems biology?. In: FM 2009: Formal Methods, Lecture Notes in Computer Science. Vol. 5850, Berlin/Heidelberg, Springer, pp. 16-22.
    • (2009) What can Formal Methods bring to Systems Biology? , vol.5850 , pp. 16-22
    • Bonzanni, N.1
  • 4
    • 70350596826 scopus 로고    scopus 로고
    • A robust and highly efficient immune cell reprogramming system
    • Bussmann, L.H. et al. (2009) A robust and highly efficient immune cell reprogramming system. Cell Stem Cell, 5, 554-566.
    • (2009) Cell Stem Cell , vol.5 , pp. 554-566
    • Bussmann, L.H.1
  • 5
    • 35848943273 scopus 로고    scopus 로고
    • Hematopoietic fingerprints: An expression database of stem cells and their progeny
    • Chambers, S.M. et al. (2007) Hematopoietic fingerprints: An expression database of stem cells and their progeny. Cell Stem Cell, 1, 578-591.
    • (2007) Cell Stem Cell , vol.1 , pp. 578-591
    • Chambers, S.M.1
  • 6
    • 59149091124 scopus 로고    scopus 로고
    • Computational modeling of the hematopoietic erythroid-myeloid switch reveals insights into cooperativity priming, and irreversibility
    • Chickarmane, V. et al. (2009) Computational modeling of the hematopoietic erythroid-myeloid switch reveals insights into cooperativity, priming, and irreversibility. PLoS Comput. Biol., 5, e1000268.
    • (2009) PLoS Comput. Biol. , vol.5
    • Chickarmane, V.1
  • 7
    • 0029129304 scopus 로고
    • Adult acute lymphoblastic leukemia at relapse. Cytogenetic immunophenotypic, and molecular changes
    • Chucrallah, A.E. et al. (1995) Adult acute lymphoblastic leukemia at relapse. Cytogenetic, immunophenotypic, and molecular changes. Cancer, 76, 985-991.
    • (1995) Cancer , vol.76 , pp. 985-991
    • Chucrallah, A.E.1
  • 8
    • 45849093636 scopus 로고    scopus 로고
    • Boolean network model predicts cell cycle sequence of fission yeast
    • Davidich, M.I. and Bornholdt, S. (2008) Boolean network model predicts cell cycle sequence of fission yeast. PLoS One, 3, e1672.
    • (2008) PLoS One , vol.3
    • Davidich, M.I.1    Bornholdt, S.2
  • 10
    • 0036500609 scopus 로고    scopus 로고
    • A genomic regulatory network for development
    • Davidson, E.H. et al. (2002) A genomic regulatory network for development. Science, 295, 1669-1678.
    • (2002) Science , vol.295 , pp. 1669-1678
    • Davidson, E.H.1
  • 11
    • 80054746874 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein alpha (C/EBP(alpha))-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation
    • Di Tullio, A. et al. (2011) CCAAT/enhancer binding protein alpha (C/EBP(alpha))-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation. Proc. Natl Acad. Sci. USA, 108, 17016-17021.
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 17016-17021
    • Di Tullio, A.1
  • 12
    • 14644412924 scopus 로고    scopus 로고
    • Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development
    • Donaldson, I.J. et al. (2005) Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development. Hum. Mol. Genet., 14, 595-601.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 595-601
    • Donaldson, I.J.1
  • 13
    • 14644412924 scopus 로고    scopus 로고
    • Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development
    • Donaldson, I.J. et al. (2005) Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development. Hum. Mol. Genet., 14, 595-601.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 595-601
    • Donaldson, I.J.1
  • 14
    • 72949096573 scopus 로고    scopus 로고
    • From genes to cells to tissues-modelling the haematopoietic system
    • Foster, S.D. et al. (2009) From genes to cells to tissues-modelling the haematopoietic system. Mol. Biosyst., 5, 1413-1420.
    • (2009) Mol. Biosyst. , vol.5 , pp. 1413-1420
    • Foster, S.D.1
  • 15
    • 50549088838 scopus 로고    scopus 로고
    • Synchronous versus asynchronous modeling of gene regulatory networks
    • Garg, A. et al. (2008) Synchronous versus asynchronous modeling of gene regulatory networks. Bioinformatics, 24, 1917-1925.
    • (2008) Bioinformatics , vol.24 , pp. 1917-1925
    • Garg, A.1
  • 16
    • 66349086263 scopus 로고    scopus 로고
    • Modeling stochasticity and robustness in gene regulatory networks
    • Garg, A. et al. (2009) Modeling stochasticity and robustness in gene regulatory networks. Bioinformatics, 25, i101-i109.
    • (2009) Bioinformatics , vol.25
    • Garg, A.1
  • 17
    • 58149488711 scopus 로고    scopus 로고
    • A gene regulatory network armature for T lymphocyte specification
    • Georgescu, C. et al. (2008) A gene regulatory network armature for T lymphocyte specification. Proc. Natl Acad. Sci. USA, 105, 20100-20105.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 20100-20105
    • Georgescu, C.1
  • 18
    • 4344660909 scopus 로고    scopus 로고
    • Transcriptional regulation of haematopoiesis
    • Göttgens, B. (2004) Transcriptional regulation of haematopoiesis. Vox Sang., 87 (Suppl. 1), 15-19.
    • (2004) Vox Sang. , vol.87 , Issue.SUPPL.1 , pp. 15-19
    • Göttgens, B.1
  • 19
    • 0030732851 scopus 로고    scopus 로고
    • Transcription of the SCL gene in erythroid and CD34 positive primitive myeloid cells is controlled by a complex network of lineagerestricted chromatin-dependent and chromatin-independent regulatory elements
    • Göttgens, B. et al. (1997) Transcription of the SCL gene in erythroid and CD34 positive primitive myeloid cells is controlled by a complex network of lineagerestricted chromatin-dependent and chromatin-independent regulatory elements. Oncogene, 15, 2419-2428.
    • (1997) Oncogene , vol.15 , pp. 2419-2428
    • Göttgens, B.1
  • 20
    • 18444415449 scopus 로고    scopus 로고
    • Establishing the transcriptional programme for blood: The SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors
    • Göttgens, B. et al. (2002) Establishing the transcriptional programme for blood: The SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors. EMBO J., 21, 3039-3050.
    • (2002) EMBO J. , vol.21 , pp. 3039-3050
    • Göttgens, B.1
  • 21
    • 2942526253 scopus 로고    scopus 로고
    • The scl +18/19 stem cell enhancer is not required for hematopoiesis: Identification of a 50 bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1
    • Göttgens, B. et al. (2004) The scl +18/19 stem cell enhancer is not required for hematopoiesis: Identification of a 50 bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1. Mol. Cell. Biol., 24, 1870-1883.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 1870-1883
    • Göttgens, B.1
  • 22
    • 0041806587 scopus 로고    scopus 로고
    • GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling
    • Grass, J.A. et al. (2003) GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling. Proc. Natl Acad. Sci. USA, 100, 8811-8816.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 8811-8816
    • Grass, J.A.1
  • 23
    • 0037099497 scopus 로고    scopus 로고
    • Transcription factor-mediated lineage switching reveals plasticity in primary committed progenitor cells
    • Heyworth, C. et al. (2002) Transcription factor-mediated lineage switching reveals plasticity in primary committed progenitor cells. EMBO J., 21, 3770-3781.
    • (2002) EMBO J. , vol.21 , pp. 3770-3781
    • Heyworth, C.1
  • 24
    • 0037174669 scopus 로고    scopus 로고
    • Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop
    • Hirata, H. et al. (2002) Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop. Science, 298, 840-843.
    • (2002) Science , vol.298 , pp. 840-843
    • Hirata, H.1
  • 25
    • 0030954167 scopus 로고    scopus 로고
    • Multilineage gene expression precedes commitment in the hemopoietic system
    • Hu, M. et al. (1997)Multilineage gene expression precedes commitment in the hemopoietic system. Genes Dev., 11, 774-785.
    • (1997) Genes Dev. , vol.11 , pp. 774-785
    • Hu, M.1
  • 26
    • 34247629588 scopus 로고    scopus 로고
    • Genetic reconstruction of a functional transcriptional regulatory network
    • Hu, Z. et al. (2007) Genetic reconstruction of a functional transcriptional regulatory network. Nat. Genet., 39, 683-687.
    • (2007) Nat. Genet. , vol.39 , pp. 683-687
    • Hu, Z.1
  • 27
    • 70450162700 scopus 로고    scopus 로고
    • Non-genetic heterogeneity of cells in development: Nore than just noise
    • Huang, S. (2009) Non-genetic heterogeneity of cells in development: Nore than just noise. Development, 136, 3853-3862.
    • (2009) Development , vol.136 , pp. 3853-3862
    • Huang, S.1
  • 28
    • 52649087274 scopus 로고    scopus 로고
    • Modelling and analysis of gene regulatory networks
    • Karlebach, G. and Shamir, R. (2008) Modelling and analysis of gene regulatory networks. Nat. Rev. Mol. Cell Biol., 9, 770-780.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 770-780
    • Karlebach, G.1    Shamir, R.2
  • 29
    • 0345598902 scopus 로고    scopus 로고
    • Random boolean network models and the yeast transcriptional network
    • Kauffman, S. et al. (2003) Random Boolean network models and the yeast transcriptional network. Proc. Natl Acad. Sci. USA, 100, 14796-14799.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 14796-14799
    • Kauffman, S.1
  • 30
    • 33646337667 scopus 로고    scopus 로고
    • A methodology for the structural and functional analysis of signaling and regulatory networks
    • Klamt, S. et al. (2006) A methodology for the structural and functional analysis of signaling and regulatory networks. BMC Bioinformatics, 7, 56.
    • (2006) BMC Bioinformatics , vol.7 , pp. 56
    • Klamt, S.1
  • 31
    • 23344452957 scopus 로고    scopus 로고
    • GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene
    • Kobayashi-Osaki, M. et al. (2005) GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene. Mol. Cell. Biol., 25, 7005-7020.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 7005-7020
    • Kobayashi-Osaki, M.1
  • 32
    • 80051505603 scopus 로고    scopus 로고
    • Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network
    • Krumsiek, J. et al. (2011) Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network. PLoS One, 6, e22649.
    • (2011) PLoS One , vol.6
    • Krumsiek, J.1
  • 33
    • 0029066359 scopus 로고
    • GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts
    • Kulessa, H. et al. (1995) GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. Genes Dev., 9, 1250-1262.
    • (1995) Genes Dev. , vol.9 , pp. 1250-1262
    • Kulessa, H.1
  • 34
    • 0842332406 scopus 로고    scopus 로고
    • Dynamics of the p53-Mdm2 feedback loop in individual cells
    • Lahav, G. et al. (2004) Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat. Genet., 36, 147-150.
    • (2004) Nat. Genet. , vol.36 , pp. 147-150
    • Lahav, G.1
  • 35
    • 42449101777 scopus 로고    scopus 로고
    • Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver
    • Landry, J.R. et al. (2008) Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver. Blood, 111, 3005-3014.
    • (2008) Blood , vol.111 , pp. 3005-3014
    • Landry, J.R.1
  • 36
    • 1842687878 scopus 로고    scopus 로고
    • The yeast cell-cycle network is robustly designed
    • Li, F. et al. (2004) The yeast cell-cycle network is robustly designed. Proc. Natl Acad. Sci. USA, 101, 4781-4786.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 4781-4786
    • Li, F.1
  • 37
    • 1642351580 scopus 로고    scopus 로고
    • Role of RUNX1 in adult hematopoiesis: Analysis of RUNX1-IRES-GFP knock-in mice reveals differential lineage expression
    • Lorsbach, R.B. et al. (2004) Role of RUNX1 in adult hematopoiesis: Analysis of RUNX1-IRES-GFP knock-in mice reveals differential lineage expression. Blood, 103, 2522-2529.
    • (2004) Blood , vol.103 , pp. 2522-2529
    • Lorsbach, R.B.1
  • 38
    • 77957308820 scopus 로고    scopus 로고
    • Timing robustness in the budding and fission yeast cell cycles
    • Mangla, K. et al. (2010) Timing robustness in the budding and fission yeast cell cycles. PLoS One, 5, e8906.
    • (2010) PLoS One , vol.5
    • Mangla, K.1
  • 39
    • 33646346114 scopus 로고    scopus 로고
    • A method for the generation of standardized qualitative dynamical systems of regulatory networks
    • Mendoza, L. and Xenarios, I. (2006) A method for the generation of standardized qualitative dynamical systems of regulatory networks. Theor. Biol. Med. Model, 3, 13.
    • (2006) Theor. Biol. Med. Model , vol.3 , pp. 13
    • Mendoza, L.1    Xenarios, I.2
  • 40
    • 79953721660 scopus 로고    scopus 로고
    • Global gene expression analysis of human erythroid progenitors
    • Merryweather-Clarke, A.T. et al. (2011) Global gene expression analysis of human erythroid progenitors. Blood, 117, 96-108.
    • (2011) Blood , vol.117 , pp. 96-108
    • Merryweather-Clarke, A.T.1
  • 41
    • 58549117664 scopus 로고    scopus 로고
    • Transcriptional regulatory networks in haematopoiesis
    • Miranda-Saavedra, D. and Göttgens, B. (2008) Transcriptional regulatory networks in haematopoiesis. Curr. Opin. Genet. Dev., 18, 530-535.
    • (2008) Curr. Opin. Genet. Dev. , vol.18 , pp. 530-535
    • Miranda-Saavedra, D.1    Göttgens, B.2
  • 42
    • 38349165800 scopus 로고    scopus 로고
    • Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer
    • Nottingham, W.T. et al. (2007) Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer. Blood, 110, 4188-4197.
    • (2007) Blood , vol.110 , pp. 4188-4197
    • Nottingham, W.T.1
  • 43
    • 20144368117 scopus 로고    scopus 로고
    • Potential autoregulation of transcription factor PU.1 by an upstream regulatory element
    • Okuno, Y. et al. (2005) Potential autoregulation of transcription factor PU.1 by an upstream regulatory element. Mol. Cell. Biol., 25, 2832-2845.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 2832-2845
    • Okuno, Y.1
  • 44
    • 36749094041 scopus 로고    scopus 로고
    • Gata2 Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development
    • Pimanda, J.E. et al. (2007) Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development. Proc. Natl Acad. Sci. USA., 104, 17692-17697.
    • (2007) Proc. Natl Acad. Sci. USA. , vol.104 , pp. 17692-17697
    • Pimanda, J.E.1
  • 45
    • 84862778068 scopus 로고    scopus 로고
    • Inferring rules of lineage commitment in haematopoiesis
    • Pina, C. et al. (2012) Inferring rules of lineage commitment in haematopoiesis. Nat. Cell Biol., 14, 287-294.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 287-294
    • Pina, C.1
  • 46
    • 33749444296 scopus 로고    scopus 로고
    • Evidence for diversity in transcriptional profiles of single hematopoietic stem cells
    • Ramos, C.A. et al. (2006) Evidence for diversity in transcriptional profiles of single hematopoietic stem cells. PLoS Genet., 2, e159.
    • (2006) PLoS Genet. , vol.2
    • Ramos, C.A.1
  • 47
    • 33746040437 scopus 로고    scopus 로고
    • Towards an understanding of lineage specification in hematopoietic stem cells: A mathematical model for the interaction of transcription factors GATA-1 and PU.1
    • Roeder, I. and Glauche, I. (2006) Towards an understanding of lineage specification in hematopoietic stem cells: A mathematical model for the interaction of transcription factors GATA-1 and PU.1. J. Theor. Biol., 241, 852-865.
    • (2006) J. Theor. Biol. , vol.241 , pp. 852-865
    • Roeder, I.1    Glauche, I.2
  • 48
    • 84864008966 scopus 로고    scopus 로고
    • Gene Expression Commons: An open platform for absolute gene expression profiling
    • Seita, J. et al. (2012) Gene Expression Commons: An open platform for absolute gene expression profiling. PLoS One, 7, e40321.
    • (2012) PLoS One , vol.7
    • Seita, J.1
  • 49
    • 0032190631 scopus 로고    scopus 로고
    • A transcription factor party during blood cell differentiation
    • Sieweke, M.H. and Graf, T. (1998) A transcription factor party during blood cell differentiation. Curr. Opin. Genet. Dev., 8, 545-551.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 545-551
    • Sieweke, M.H.1    Graf, T.2
  • 50
    • 38449100969 scopus 로고    scopus 로고
    • A gene regulatory network subcircuit drives a dynamic pattern of gene expression
    • Smith, J. et al. (2007) A gene regulatory network subcircuit drives a dynamic pattern of gene expression. Science, 318, 794-797.
    • (2007) Science , vol.318 , pp. 794-797
    • Smith, J.1
  • 51
    • 70349728484 scopus 로고    scopus 로고
    • A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates
    • Spooner, C.J. et al. (2009) A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. Immunity, 31, 576-586.
    • (2009) Immunity , vol.31 , pp. 576-586
    • Spooner, C.J.1
  • 52
    • 0021280294 scopus 로고
    • Lineage switch in acute leukemia
    • Stass, S. et al. (1984) Lineage switch in acute leukemia. Blood, 64, 701-706.
    • (1984) Blood , vol.64 , pp. 701-706
    • Stass, S.1
  • 53
    • 33745000256 scopus 로고    scopus 로고
    • Genetic regulatory networks programming hematopoietic stem cells and erythroid lineage specification
    • Swiers, G. et al. (2006) Genetic regulatory networks programming hematopoietic stem cells and erythroid lineage specification. Dev. Biol., 294, 525-540.
    • (2006) Dev. Biol. , vol.294 , pp. 525-540
    • Swiers, G.1
  • 54
    • 0025948178 scopus 로고
    • Regulatory networks seen as asynchronous automata: A logical description
    • Thomas, R. (1991) Regulatory networks seen as asynchronous automata: A logical description. J. Theor. Biol., 153, 1-23.
    • (1991) J. Theor. Biol. , vol.153 , pp. 1-23
    • Thomas, R.1
  • 55
    • 0029267491 scopus 로고
    • Dynamical behaviour of biological regulatory networks-I Biological role of feedback loops and practical use of the concept of the loopcharacteristic state
    • Thomas, R. et al. (1995) Dynamical behaviour of biological regulatory networks-I. Biological role of feedback loops and practical use of the concept of the loopcharacteristic state. Bull. Math. Biol., 57, 247-276.
    • (1995) Bull. Math. Biol. , vol.57 , pp. 247-276
    • Thomas, R.1
  • 56
    • 79959825899 scopus 로고    scopus 로고
    • ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer
    • Thoms, J.A. et al. (2011) ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer. Blood, 117, 7079-7089.
    • (2011) Blood , vol.117 , pp. 7079-7089
    • Thoms, J.A.1
  • 57
    • 63849118537 scopus 로고    scopus 로고
    • High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle
    • Tipping, A.J. et al. (2009) High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle. Blood, 113, 2661-2672.
    • (2009) Blood , vol.113 , pp. 2661-2672
    • Tipping, A.J.1
  • 58
    • 0029120629 scopus 로고
    • Immunophenotypic changes between diagnosis and relapse in childhood acute lymphoblastic leukemia
    • van Wering, E.R. et al. (1995) Immunophenotypic changes between diagnosis and relapse in childhood acute lymphoblastic leukemia. Leukemia, 9, 1523-1533.
    • (1995) Leukemia , vol.9 , pp. 1523-1533
    • Van Wering, E.R.1
  • 59
    • 0032789064 scopus 로고    scopus 로고
    • Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene
    • Vyas, P. et al. (1999) Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene. Development, 126, 2799-2811.
    • (1999) Development , vol.126 , pp. 2799-2811
    • Vyas, P.1
  • 60
    • 33845218548 scopus 로고    scopus 로고
    • Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR
    • Warren, L. et al. (2006) Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR. Proc. Natl Acad. Sci. USA, 103, 17807-17812.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 17807-17812
    • Warren, L.1
  • 61
    • 67049108075 scopus 로고    scopus 로고
    • The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development
    • Wilson, N.K. et al. (2009) The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development. Blood, 113, 5456-5465.
    • (2009) Blood , vol.113 , pp. 5456-5465
    • Wilson, N.K.1
  • 62
    • 80054832679 scopus 로고    scopus 로고
    • Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes
    • Wong, P. et al. (2011) Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes. Blood, 118, e128-138.
    • (2011) Blood , vol.118
    • Wong, P.1


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