-
1
-
-
77951026738
-
For Society for Healthcare Epidemiology of America, Infectious Diseases Society of America. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA)
-
Cohen SH, Gerding DN, Johnson S, et al; For Society for Healthcare Epidemiology of America, Infectious Diseases Society of America. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol. 2010;31(5):431-455.
-
(2010)
Infect Control Hosp Epidemiol
, vol.31
, Issue.5
, pp. 431-455
-
-
Cohen, S.H.1
Gerding, D.N.2
Johnson, S.3
-
2
-
-
0019180153
-
Clinical and laboratory observations in Clostridium difficile colitis
-
Bartlett JG, Taylor NS, Chang T, Dzink J. Clinical and laboratory observations in Clostridium difficile colitis. Am J Clin Nutr. 1980; 33(Suppl 11):2521-2526.
-
(1980)
Am J Clin Nutr
, vol.33
, Issue.SUPPL. 11
, pp. 2521-2526
-
-
Bartlett, J.G.1
Taylor, N.S.2
Chang, T.3
Dzink, J.4
-
3
-
-
0019949758
-
Clostridium difficile and its cytotoxin in feces of patients with antimicrobial agent-associated diarrhea and miscellaneous conditions
-
George WL, Rolfe RD, Finegold SM. Clostridium difficile and its cytotoxin in feces of patients with antimicrobial agent-associated diarrhea and miscellaneous conditions. J Clin Microbiol. 1982;15(6):1049-1053.
-
(1982)
J Clin Microbiol
, vol.15
, Issue.6
, pp. 1049-1053
-
-
George, W.L.1
Rolfe, R.D.2
Finegold, S.M.3
-
5
-
-
84868014572
-
-
Healthcare Cost and Utilization Project Statistical Brief #124. Rockville, MD: Agency for Healthcare Research and Quality; 2012. Available from, Accessed April 29, 2013
-
Lucado J, Gould C, Elixhauser A. Clostridium Difficile Infections (CDI) in Hospital Stays, 2009. Healthcare Cost and Utilization Project Statistical Brief #124. Rockville, MD: Agency for Healthcare Research and Quality; 2012. Available from: http://www.hcup-us.ahrq.gov/reports/statbriefs/sb124.pdf. Accessed April 29, 2013.
-
(2009)
Clostridium Difficile Infections (CDI) In Hospital Stays
-
-
Lucado, J.1
Gould, C.2
Elixhauser, A.3
-
6
-
-
61549089404
-
Effects of treatment with antimicrobial agents on the human colonic microflora
-
Rafii F, Sutherland JB, Cerniglia CE. Effects of treatment with antimicrobial agents on the human colonic microflora. Ther Clin Risk Manag. 2008;4(6):1343-1358.
-
(2008)
Ther Clin Risk Manag
, vol.4
, Issue.6
, pp. 1343-1358
-
-
Rafii, F.1
Sutherland, J.B.2
Cerniglia, C.E.3
-
7
-
-
79851470700
-
The enterotoxicity of Clostridium difficile
-
Sun X, Savidge T, Feng H. The enterotoxicity of Clostridium difficile. Toxins (Basel). 2010;2(7):1848-1880.
-
(2010)
Toxins (Basel)
, vol.2
, Issue.7
, pp. 1848-1880
-
-
Sun, X.1
Savidge, T.2
Feng, H.3
-
8
-
-
0031041293
-
Risk of diarrhoea, Clostridium difficile and cefotaxime in the elderly
-
Starr JM, Impallomeni M. Risk of diarrhoea, Clostridium difficile and cefotaxime in the elderly. Biomed Pharmacother. 1997;51(2): 63-67.
-
(1997)
Biomed Pharmacother
, vol.51
, Issue.2
, pp. 63-67
-
-
Starr, J.M.1
Impallomeni, M.2
-
9
-
-
0026650077
-
Effects of antibiotics and other drugs on toxin production in Clostridium difficile in vitro and in vivo
-
Barc MC, Depitre C, Corthier G, Collignon A, Su WJ, Bourlioux P. Effects of antibiotics and other drugs on toxin production in Clostridium difficile in vitro and in vivo. Antimicrob Agents Chemother. 1992;36(6):1332-1335.
-
(1992)
Antimicrob Agents Chemother
, vol.36
, Issue.6
, pp. 1332-1335
-
-
Barc, M.C.1
Depitre, C.2
Corthier, G.3
Collignon, A.4
Su, W.J.5
Bourlioux, P.6
-
11
-
-
43249096532
-
The case for vancomycin as the preferred drug for treatment of Clostridium difficile infection
-
Bartlett JG. The case for vancomycin as the preferred drug for treatment of Clostridium difficile infection. Clin Infect Dis. 2008;46(10): 1489-1492.
-
(2008)
Clin Infect Dis
, vol.46
, Issue.10
, pp. 1489-1492
-
-
Bartlett, J.G.1
-
12
-
-
80051957059
-
Efficacy of fidaxomicin versus vancomycin as therapy for Clostridium difficile infection in individuals taking concomitant antibiotics for other concurrent infections
-
Mullane KM, Miller MA, Weiss K, et al. Efficacy of fidaxomicin versus vancomycin as therapy for Clostridium difficile infection in individuals taking concomitant antibiotics for other concurrent infections. Clin Infect Dis. 2011;53(5):440-447.
-
(2011)
Clin Infect Dis
, vol.53
, Issue.5
, pp. 440-447
-
-
Mullane, K.M.1
Miller, M.A.2
Weiss, K.3
-
13
-
-
70649107673
-
For European Society of Clinical Microbiology and Infectious Diseases. European Society of Clinical Microbiology and Infectious Diseases (ESCMID): Treatment guidance document for Clostridium difficile infection (CDI)
-
Bauer MP, Kuijper EJ, van Dissel JT; For European Society of Clinical Microbiology and Infectious Diseases. European Society of Clinical Microbiology and Infectious Diseases (ESCMID): treatment guidance document for Clostridium difficile infection (CDI). Clin Microbiol Infect. 2009;15(12):1067-1079.
-
(2009)
Clin Microbiol Infect
, vol.15
, Issue.12
, pp. 1067-1079
-
-
Bauer, M.P.1
Kuijper, E.J.2
van Dissel, J.T.3
-
14
-
-
0028945667
-
Recommendations for preventing the spread of vancomycin resistance: Recommendations of the Hospital Infection Control Practices Advisory Committee (HICPAC)
-
Recommendations for preventing the spread of vancomycin resistance: recommendations of the Hospital Infection Control Practices Advisory Committee (HICPAC). Am J Infect Control. 1995;23(2):87-94.
-
(1995)
Am J Infect Control
, vol.23
, Issue.2
, pp. 87-94
-
-
-
15
-
-
46249099130
-
Both oral metronidazole and oral vancomycin promote persistent overgrowth of vancomycin-resistant enterococci during treatment of Clostridium difficile-associated disease
-
Al-Nassir WN, Sethi AK, Li Y, Pultz MJ, Riggs MM, Donskey CJ. Both oral metronidazole and oral vancomycin promote persistent overgrowth of vancomycin-resistant enterococci during treatment of Clostridium difficile-associated disease. Antimicrob Agents Chemother. 2008;52(7):2403-2406.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, Issue.7
, pp. 2403-2406
-
-
Al-Nassir, W.N.1
Sethi, A.K.2
Li, Y.3
Pultz, M.J.4
Riggs, M.M.5
Donskey, C.J.6
-
16
-
-
34547133720
-
A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity
-
Zar FA, Bakkanagari SR, Moorthi KM, Davis MB. A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity. Clin Infect Dis. 2007;45(3):302-307.
-
(2007)
Clin Infect Dis
, vol.45
, Issue.3
, pp. 302-307
-
-
Zar, F.A.1
Bakkanagari, S.R.2
Moorthi, K.M.3
Davis, M.B.4
-
17
-
-
84879980668
-
-
Results of a phase III trial comparing tolevamer, vancomycin and metronidazole in patients with Clostridium difficile-associated diarrhea [abstact K-425a]
-
Louie TJGM, Grimard D, Johnson S, Poirier A, Weiss K; For the Tolevamer Study Group. Results of a phase III trial comparing tolevamer, vancomycin and metronidazole in patients with Clostridium difficile-associated diarrhea [abstact K-425a]. 2007.
-
(2007)
For the Tolevamer Study Group
-
-
Louie, T.J.G.M.1
Grimard, D.2
Johnson, S.3
Poirier, A.4
Weiss, K.5
-
18
-
-
23944507069
-
Treatment of Clostridium difficile-associated disease: Old therapies and new strategies
-
Aslam S, Hamill RJ, Musher DM. Treatment of Clostridium difficile-associated disease: old therapies and new strategies. Lancet Infect Dis. 2005;5(9):549-557.
-
(2005)
Lancet Infect Dis
, vol.5
, Issue.9
, pp. 549-557
-
-
Aslam, S.1
Hamill, R.J.2
Musher, D.M.3
-
19
-
-
54549118257
-
Emergence of reduced susceptibility to metronidazole in Clostridium difficile
-
Baines SD, O'Connor R, Freeman J, et al. Emergence of reduced susceptibility to metronidazole in Clostridium difficile. J Antimicrob Chemother. 2008;62(5):1046-1052.
-
(2008)
J Antimicrob Chemother
, vol.62
, Issue.5
, pp. 1046-1052
-
-
Baines, S.D.1
O'Connor, R.2
Freeman, J.3
-
20
-
-
67649391053
-
Clostridium difficile infection: New developments in epidemiology and pathogenesis
-
Rupnik M, Wilcox MH, Gerding DN. Clostridium difficile infection: new developments in epidemiology and pathogenesis. Nat Rev Microbiol. 2009;7(7):526-536.
-
(2009)
Nat Rev Microbiol
, vol.7
, Issue.7
, pp. 526-536
-
-
Rupnik, M.1
Wilcox, M.H.2
Gerding, D.N.3
-
21
-
-
0022491104
-
Faecal metronidazole concentrations during oral and intravenous therapy for antibiotic associated colitis due to Clostridium difficile
-
Bolton RP, Culshaw MA. Faecal metronidazole concentrations during oral and intravenous therapy for antibiotic associated colitis due to Clostridium difficile. Gut. 1986;27(10):1169-1172.
-
(1986)
Gut
, vol.27
, Issue.10
, pp. 1169-1172
-
-
Bolton, R.P.1
Culshaw, M.A.2
-
22
-
-
79551527297
-
For OPT-80-003 Clinical Study Group. Fidaxomicin versus vancomycin for Clostridium difficile infection
-
Louie TJ, Miller MA, Mullane KM, et al; For OPT-80-003 Clinical Study Group. Fidaxomicin versus vancomycin for Clostridium difficile infection. N Engl J Med. 2011;364(5):422-431.
-
(2011)
N Engl J Med
, vol.364
, Issue.5
, pp. 422-431
-
-
Louie, T.J.1
Miller, M.A.2
Mullane, K.M.3
-
23
-
-
84859007390
-
For OPT-80-004 Clinical Study Group. Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: A double-blind, non-inferiority, randomised controlled trial
-
Cornely OA, Crook DW, Esposito R, et al; For OPT-80-004 Clinical Study Group. Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: a double-blind, non-inferiority, randomised controlled trial. Lancet Infect Dis. 2012; 12(4):281-289.
-
(2012)
Lancet Infect Dis
, vol.12
, Issue.4
, pp. 281-289
-
-
Cornely, O.A.1
Crook, D.W.2
Esposito, R.3
-
24
-
-
84903214227
-
For the CDI Study Group. Efficacy and safety of the lipopeptide CB-183,315 for the treatment of Clostridium difficile infection [Abstract K-205a]
-
September 17-20, Chicago, IL
-
Patino HSC, Louie T, Bernardo P, Friedland I; For the CDI Study Group. Efficacy and safety of the lipopeptide CB-183,315 for the treatment of Clostridium difficile infection [Abstract K-205a]. Proceedings of the 51st Internatl Congr Antimicr Ag Chemother; September 17-20, 2011; Chicago, IL.
-
(2011)
Proceedings of the 51st Internatl Congr Antimicr Ag Chemother
-
-
Patino, H.S.C.1
Louie, T.2
Bernardo, P.3
Friedland, I.4
-
25
-
-
67349239352
-
Recurrent Clostridium difficile infection: A review of risk factors, treatments, and outcomes
-
Johnson S. Recurrent Clostridium difficile infection: a review of risk factors, treatments, and outcomes. J Infect. 2009;58(6):403-410.
-
(2009)
J Infect
, vol.58
, Issue.6
, pp. 403-410
-
-
Johnson, S.1
-
26
-
-
0036311186
-
Breaking the cycle: Treatment strategies for 163 cases of recurrent Clostridium difficile disease
-
McFarland LV, Elmer GW, Surawicz CM. Breaking the cycle: treatment strategies for 163 cases of recurrent Clostridium difficile disease. Am J Gastroenterol. 2002;97(7):1769-1775.
-
(2002)
Am J Gastroenterol
, vol.97
, Issue.7
, pp. 1769-1775
-
-
McFarland, L.V.1
Elmer, G.W.2
Surawicz, C.M.3
-
27
-
-
79961203458
-
Fidaxomicin: First-in-class macrocyclic antibiotic
-
Mullane KM, Gorbach S. Fidaxomicin: first-in-class macrocyclic antibiotic. Expert Rev Anti Infect Ther. 2011;9(7):767-777.
-
(2011)
Expert Rev Anti Infect Ther
, vol.9
, Issue.7
, pp. 767-777
-
-
Mullane, K.M.1
Gorbach, S.2
-
28
-
-
0016680833
-
Lipiarmycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies
-
Parenti F, Pagani H, Beretta G. Lipiarmycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies. J Antibiot (Tokyo). 1975;28(4):247-252.
-
(1975)
J Antibiot (Tokyo)
, vol.28
, Issue.4
, pp. 247-252
-
-
Parenti, F.1
Pagani, H.2
Beretta, G.3
-
29
-
-
0023250466
-
Tiacumicins, a novel complex of 18-membered macrolide antibiotics. I. Taxonomy, fermentation and antibacterial activity
-
Theriault RJ, Karwowski JP, Jackson M, et al. Tiacumicins, a novel complex of 18-membered macrolide antibiotics. I. Taxonomy, fermentation and antibacterial activity. J Antibiot (Tokyo). 1987;40(5): 567-574.
-
(1987)
J Antibiot (Tokyo)
, vol.40
, Issue.5
, pp. 567-574
-
-
Theriault, R.J.1
Karwowski, J.P.2
Jackson, M.3
-
30
-
-
80054711588
-
Comparative susceptibilities to fidaxomicin (OPT-80) of isolates collected at baseline, recurrence, and failure from patients in two phase III trials of fidaxomicin against Clostridium difficile infection
-
Goldstein EJ, Citron DM, Sears P, Babakhani F, Sambol SP, Gerding DN. Comparative susceptibilities to fidaxomicin (OPT-80) of isolates collected at baseline, recurrence, and failure from patients in two phase III trials of fidaxomicin against Clostridium difficile infection. Antimicrob Agents Chemother. 2011;55(11):5194-5199.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.11
, pp. 5194-5199
-
-
Goldstein, E.J.1
Citron, D.M.2
Sears, P.3
Babakhani, F.4
Sambol, S.P.5
Gerding, D.N.6
-
31
-
-
77951231746
-
In vitro activity of fidaxomicin (OPT-80) tested against contemporary clinical isolates of Staphylococcus spp. and Enterococcus spp
-
Biedenbach DJ, Ross JE, Putnam SD, Jones RN. In vitro activity of fidaxomicin (OPT-80) tested against contemporary clinical isolates of Staphylococcus spp. and Enterococcus spp. Antimicrob Agents Chemother. 2010;54(5):2273-2275.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.5
, pp. 2273-2275
-
-
Biedenbach, D.J.1
Ross, J.E.2
Putnam, S.D.3
Jones, R.N.4
-
32
-
-
0016592570
-
Lipiarmycin, a new antibiotic from Actinoplanes. II. Isolation, chemical, biological and biochemical characterization
-
Coronelli C, White RJ, Lancini GC, Parenti F. Lipiarmycin, a new antibiotic from Actinoplanes. II. Isolation, chemical, biological and biochemical characterization. J Antibiot (Tokyo). 1975;28(4): 253-259.
-
(1975)
J Antibiot (Tokyo)
, vol.28
, Issue.4
, pp. 253-259
-
-
Coronelli, C.1
White, R.J.2
Lancini, G.C.3
Parenti, F.4
-
34
-
-
0016828228
-
Lipiarmycin, a new antibiotic from Actinoplanes III. Mechanism of action
-
Sergio S, Pirali G, White R, Parenti F. Lipiarmycin, a new antibiotic from Actinoplanes III. Mechanism of action. J Antibiot (Tokyo). 1975;28(7):543-549.
-
(1975)
J Antibiot (Tokyo)
, vol.28
, Issue.7
, pp. 543-549
-
-
Sergio, S.1
Pirali, G.2
White, R.3
Parenti, F.4
-
35
-
-
80053908350
-
New target for inhibition of bacterial RNA polymerase: 'switch region'
-
Srivastava A, Talaue M, Liu S, et al. New target for inhibition of bacterial RNA polymerase: 'switch region'. Curr Opin Microbiol. 2011;14(5):532-543.
-
(2011)
Curr Opin Microbiol
, vol.14
, Issue.5
, pp. 532-543
-
-
Srivastava, A.1
Talaue, M.2
Liu, S.3
-
37
-
-
84863686440
-
For Study 003/004 Teams. Fidaxomicin versus vancomycin for Clostridium difficile infection: Meta-analysis of pivotal randomized controlled trials
-
Crook DW, Walker AS, Kean Y, et al; For Study 003/004 Teams. Fidaxomicin versus vancomycin for Clostridium difficile infection: meta-analysis of pivotal randomized controlled trials. Clin Infect Dis. 2012;55 Suppl 2:S93-S103.
-
(2012)
Clin Infect Dis
, vol.55
, Issue.SUPPL. 2
-
-
Crook, D.W.1
Walker, A.S.2
Kean, Y.3
-
38
-
-
84879938647
-
Renal Impairment and Response to Fidaxomicin versus Vancomycin in Patients with Clostridium difficile Infection [abstract]
-
October 20-23, 2011; Boston MA
-
Mullane KGY, Crook D, Cornely OA, Miller M, Louie T, Gorbach S. Renal Impairment and Response to Fidaxomicin versus Vancomycin in Patients with Clostridium difficile Infection [abstract]. Proceedings of the 49th Annual Infectious Diseases Society of America Meeting; October 20-23, 2011; Boston MA.
-
Proceedings of the 49th Annual Infectious Diseases Society of America Meeting
-
-
Mullane, K.G.Y.1
Crook, D.2
Cornely, O.A.3
Miller, M.4
Louie, T.5
Gorbach, S.6
-
39
-
-
84879981448
-
Clostridium difficile-associated diarrhea in cancer patients treated with fidaxomicin or vancomycin
-
June 1-5, Chicago, IL
-
Cornely OAMM, Fantin B, Mullane K, Kean Y, Gorbach S. Clostridium difficile-associated diarrhea in cancer patients treated with fidaxomicin or vancomycin. Proceedings of the American Society of Clinical Oncology Abstract #9067; June 1-5, 2012; Chicago, IL.
-
(2012)
Proceedings of the American Society of Clinical Oncology Abstract #9067
-
-
Cornely, O.A.M.M.1
Fantin, B.2
Mullane, K.3
Kean, Y.4
Gorbach, S.5
-
40
-
-
84879889600
-
Clinical outcomes for cancer patients with Clostridium difficile infection (CDI) Poster 2289
-
March 31-April 3, London, UK
-
Cornely OAMM, Fantin B, Mullane K, Kean Y, Gorbach S. Clinical outcomes for cancer patients with Clostridium difficile infection (CDI) Poster 2289. Proceedings of the European Congress of Clinical Microbiology and Infectious Diseases. March 31-April 3, 2012; London, UK.
-
(2012)
Proceedings of the European Congress of Clinical Microbiology and Infectious Diseases
-
-
Cornely, O.A.M.M.1
Fantin, B.2
Mullane, K.3
Kean, Y.4
Gorbach, S.5
-
41
-
-
84873988578
-
Effect of age on treatment outcomes in Clostridium difficile infection
-
Louie TJ, Miller MA, Crook DW, et al. Effect of age on treatment outcomes in Clostridium difficile infection. J Am Geriatr Soc. 2013;61(2):222-230.
-
(2013)
J Am Geriatr Soc
, vol.61
, Issue.2
, pp. 222-230
-
-
Louie, T.J.1
Miller, M.A.2
Crook, D.W.3
-
42
-
-
33947304450
-
Drug evaluation: OPT-80, a narrow-spectrum macrocyclic antibiotic
-
Johnson AP. Drug evaluation: OPT-80, a narrow-spectrum macrocyclic antibiotic. Curr Opin Investig Drugs. 2007;8(2):168-173.
-
(2007)
Curr Opin Investig Drugs
, vol.8
, Issue.2
, pp. 168-173
-
-
Johnson, A.P.1
-
43
-
-
80051805496
-
Postantibiotic effect of fidaxomicin and its major metabolite, OP-1118, against Clostridium difficile
-
Babakhani F, Gomez A, Robert N, Sears P. Postantibiotic effect of fidaxomicin and its major metabolite, OP-1118, against Clostridium difficile. Antimicrob Agents Chemother. 2011;55(9):4427-4429.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.9
, pp. 4427-4429
-
-
Babakhani, F.1
Gomez, A.2
Robert, N.3
Sears, P.4
-
44
-
-
79953232844
-
Pharmacokinetics/pharmacodynamics (PK/PD) of fidaxomicin in treatment of Clostridium Difficile infection (CDI)
-
September 12-15, San Francisco, CA
-
Sears P, Louie T, Mullane KM, et al. Pharmacokinetics/pharmacodynamics (PK/PD) of fidaxomicin in treatment of Clostridium Difficile infection (CDI). Proceedings of the 49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). September 12-15, 2009; San Francisco, CA.
-
(2009)
Proceedings of the 49th Interscience Conference On Antimicrobial Agents and Chemotherapy (ICAAC)
-
-
Sears, P.1
Louie, T.2
Mullane, K.M.3
-
45
-
-
59749084849
-
Clinical outcomes, safety, and pharmacokinetics of OPT-80 in a phase 2 trial with patients with Clostridium difficile infection
-
Louie T, Miller M, Donskey C, Mullane K, Goldstein EJ. Clinical outcomes, safety, and pharmacokinetics of OPT-80 in a phase 2 trial with patients with Clostridium difficile infection. Antimicrob Agents Chemother. 2009;53(1):223-228.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, Issue.1
, pp. 223-228
-
-
Louie, T.1
Miller, M.2
Donskey, C.3
Mullane, K.4
Goldstein, E.J.5
-
46
-
-
42549130704
-
Safety and Pharmacokinetics of OPT-80, a novel antibiotic for treatment of Clostridium difficile associated diarrhea (CDAD)
-
October 30-November 2, Washington, DC
-
Okumu FWR, Sears P, Shue YK. Safety and Pharmacokinetics of OPT-80, a novel antibiotic for treatment of Clostridium difficile associated diarrhea (CDAD). Proceedings of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). October 30-November 2, 2004; Washington, DC.
-
(2004)
Proceedings of the 44th Interscience Conference On Antimicrobial Agents and Chemotherapy (ICAAC)
-
-
Okumu, F.W.R.1
Sears, P.2
Shue, Y.K.3
-
47
-
-
84863710720
-
Fidaxomicin attains high fecal concentrations with minimal plasma concentrations following oral administration in patients with Clostridium difficile infection
-
Sears P, Crook DW, Louie TJ, Miller MA, Weiss K. Fidaxomicin attains high fecal concentrations with minimal plasma concentrations following oral administration in patients with Clostridium difficile infection. Clin Infect Dis. 2012;55 Suppl 2:S116-S120.
-
(2012)
Clin Infect Dis
, vol.55
, Issue.SUPPL. 2
-
-
Sears, P.1
Crook, D.W.2
Louie, T.J.3
Miller, M.A.4
Weiss, K.5
-
48
-
-
84879969641
-
-
DIFICID® [prescribing information]. San Diego, CA: Optimer Pharmaceuticals, Inc; May 2011, Data on File. Clinical Study Report OPT-80-004 Final. June 4, 2010. Optimer Pharmaceuticals, Inc, Data on File. Clinical Study Report OPT-80-003 Final. June 17, 2010 (Version 2). Optimer Pharmaceuticals, Inc. Available from, Accessed April 29, 2013
-
DIFICID® [prescribing information]. San Diego, CA: Optimer Pharmaceuticals, Inc; May 2011, Data on File. Clinical Study Report OPT-80-004 Final. June 4, 2010. Optimer Pharmaceuticals, Inc, Data on File. Clinical Study Report OPT-80-003 Final. June 17, 2010 (Version 2). Optimer Pharmaceuticals, Inc. Available from: http://www.drugs.com/comments/fidaxomicin/dificid.html. Accessed April 29, 2013.
-
-
-
-
49
-
-
78049517194
-
A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin
-
Tannock GW, Munro K, Taylor C, et al. A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin. Microbiology. 2010;156(Pt 11):3354-3359.
-
(2010)
Microbiology
, vol.156
, Issue.PART 11
, pp. 3354-3359
-
-
Tannock, G.W.1
Munro, K.2
Taylor, C.3
-
50
-
-
84863705179
-
Reduced acquisition and overgrowth of vancomycin-resistant enterococci and Candida species in patients treated with fidaxomicin versus vancomycin for Clostridium difficile infection
-
Nerandzic MM, Mullane K, Miller MA, Babakhani F, Donskey CJ. Reduced acquisition and overgrowth of vancomycin-resistant enterococci and Candida species in patients treated with fidaxomicin versus vancomycin for Clostridium difficile infection. Clin Infect Dis. 2012; 55 Suppl 2:S121-S126.
-
(2012)
Clin Infect Dis
, vol.55
, Issue.SUPPL. 2
-
-
Nerandzic, M.M.1
Mullane, K.2
Miller, M.A.3
Babakhani, F.4
Donskey, C.J.5
-
51
-
-
84863644993
-
Fidaxomicin preserves the intestinal microbiome during and after treatment of Clostridium difficile infection (CDI) and reduces both toxin reexpression and recurrence of CDI
-
Louie TJ, Cannon K, Byrne B, et al. Fidaxomicin preserves the intestinal microbiome during and after treatment of Clostridium difficile infection (CDI) and reduces both toxin reexpression and recurrence of CDI. Clin Infect Dis. 2012;55 Suppl 2:S132-S142.
-
(2012)
Clin Infect Dis
, vol.55
, Issue.SUPPL. 2
-
-
Louie, T.J.1
Cannon, K.2
Byrne, B.3
-
52
-
-
84873599885
-
Fidaxomicin inhibits toxin production in Clostridium difficile
-
Babakhani F, Bouillaut L, Sears P, Sims C, Gomez A, Sonenshein AL. Fidaxomicin inhibits toxin production in Clostridium difficile. J Antimicrob Chemother. 2013;68(3):515-522.
-
(2013)
J Antimicrob Chemother
, vol.68
, Issue.3
, pp. 515-522
-
-
Babakhani, F.1
Bouillaut, L.2
Sears, P.3
Sims, C.4
Gomez, A.5
Sonenshein, A.L.6
-
53
-
-
84863641928
-
Fidaxomicin inhibits spore production in Clostridium difficile
-
Babakhani F, Bouillaut L, Gomez A, Sears P, Nguyen L, Sonenshein AL. Fidaxomicin inhibits spore production in Clostridium difficile. Clin Infect Dis. 2012;55 Suppl 2:S162-S169.
-
(2012)
Clin Infect Dis
, vol.55
, Issue.SUPPL. 2
-
-
Babakhani, F.1
Bouillaut, L.2
Gomez, A.3
Sears, P.4
Nguyen, L.5
Sonenshein, A.L.6
-
54
-
-
84879891288
-
-
DIFICID ™ oral tablets, fidaxomicin oral tablets [prescribing information]. San Diego, CA: Optimer Pharmaceuticals, Inc
-
DIFICID ™ oral tablets, fidaxomicin oral tablets [prescribing information]. San Diego, CA: Optimer Pharmaceuticals, Inc; 2011.
-
(2011)
-
-
-
55
-
-
85019784896
-
Faster time to resolution of diarrhea with fidaxomicin vs vancomycin in patients with Clostridium difficile infection (CDI) [abstract]
-
October 29-November 1, Philadelphia, PA
-
Miller MAMK, Weiss K, Lentnek A, et al. Faster time to resolution of diarrhea with fidaxomicin vs vancomycin in patients with Clostridium difficile infection (CDI) [abstract]. Proceedings of the 47th Annual Infectious Diseases Society of America Meeting. October 29-November 1, 2009; Philadelphia, PA.
-
(2009)
Proceedings of the 47th Annual Infectious Diseases Society of America Meeting
-
-
Miller, M.A.M.K.1
Weiss, K.2
Lentnek, A.3
-
56
-
-
84879963044
-
-
Drugs.com. User reviews for Dificid [webpage on the Internet]. Drugs.com; 2012. Available from, Accessed December 28, 2012
-
Drugs.com. User reviews for Dificid [webpage on the Internet]. Drugs.com; 2012. Available from: http://www.drugs.com/comments/fidaxomicin/dificid.html. Accessed December 28, 2012.
-
-
-
-
57
-
-
33746626011
-
Nitazoxanide for the treatment of Clostridium difficile colitis
-
Musher DM, Logan N, Hamill RJ, et al. Nitazoxanide for the treatment of Clostridium difficile colitis. Clin Infect Dis. 2006;43(4):421-427.
-
(2006)
Clin Infect Dis
, vol.43
, Issue.4
, pp. 421-427
-
-
Musher, D.M.1
Logan, N.2
Hamill, R.J.3
-
58
-
-
58749112167
-
Nitazoxanide versus vancomycin in Clostridium difficile infection: A randomized, double-blind study
-
Musher DM, Logan N, Bressler AM, Johnson DP, Rossignol JF. Nitazoxanide versus vancomycin in Clostridium difficile infection: A randomized, double-blind study. Clin Infect Dis. 2009;48(4):e41-e46.
-
(2009)
Clin Infect Dis
, vol.48
, Issue.4
-
-
Musher, D.M.1
Logan, N.2
Bressler, A.M.3
Johnson, D.P.4
Rossignol, J.F.5
-
59
-
-
62249214077
-
Rifaximin in treatment of recurrent Clostridium difficile-associated diarrhea: An uncontrolled pilot study
-
Garey KW, Jiang ZD, Bellard A, Dupont HL. Rifaximin in treatment of recurrent Clostridium difficile-associated diarrhea: an uncontrolled pilot study. J Clin Gastroenterol. 2009;43(1):91-93.
-
(2009)
J Clin Gastroenterol
, vol.43
, Issue.1
, pp. 91-93
-
-
Garey, K.W.1
Jiang, Z.D.2
Bellard, A.3
Dupont, H.L.4
-
60
-
-
84855254075
-
Rifaximin is effective for the treatment of Clostridium difficile-associated diarrhea: Results of an open-label pilot study
-
2011
-
Rubin DT, Sohi S, Glathar M, Thomas T, Yadron N, Surma BL. Rifaximin is effective for the treatment of Clostridium difficile-associated diarrhea: results of an open-label pilot study. Gastroenterol Res Pract. 2011;2011:106978.
-
(2011)
Gastroenterol Res Pract
, pp. 106978
-
-
Rubin, D.T.1
Sohi, S.2
Glathar, M.3
Thomas, T.4
Yadron, N.5
Surma, B.L.6
-
61
-
-
33847630925
-
Interruption of recurrent Clostridium difficile-associated diarrhea episodes by serial therapy with vancomycin and rifaximin
-
Johnson S, Schriever C, Galang M, Kelly CP, Gerding DN. Interruption of recurrent Clostridium difficile-associated diarrhea episodes by serial therapy with vancomycin and rifaximin. Clin Infect Dis. 2007;44(6): 846-848.
-
(2007)
Clin Infect Dis
, vol.44
, Issue.6
, pp. 846-848
-
-
Johnson, S.1
Schriever, C.2
Galang, M.3
Kelly, C.P.4
Gerding, D.N.5
-
62
-
-
70450228421
-
Rifaximin Redux: Treatment of recurrent Clostridium difficile infections with rifaximin immediately post-vancomycin treatment
-
Johnson S, Schriever C, Patel U, Patel T, Hecht DW, Gerding DN. Rifaximin Redux: treatment of recurrent Clostridium difficile infections with rifaximin immediately post-vancomycin treatment. Anaerobe. 2009;15(6):290-291.
-
(2009)
Anaerobe
, vol.15
, Issue.6
, pp. 290-291
-
-
Johnson, S.1
Schriever, C.2
Patel, U.3
Patel, T.4
Hecht, D.W.5
Gerding, D.N.6
-
63
-
-
80055115172
-
Antibiotic treatment for Clostridium difficile-associated diarrhea in adults
-
Nelson RL, Kelsey P, Leeman H, et al. Antibiotic treatment for Clostridium difficile-associated diarrhea in adults. Cochrane Database Syst Rev. 2011;9:CD004610.
-
(2011)
Cochrane Database Syst Rev
, vol.9
-
-
Nelson, R.L.1
Kelsey, P.2
Leeman, H.3
-
64
-
-
0038311977
-
In vitro activities of ramoplanin, teicoplanin, vancomycin, linezolid, bacitracin, and four other antimicrobials against intestinal anaerobic bacteria
-
Citron DM, Merriam CV, Tyrrell KL, Warren YA, Fernandez H, Goldstein EJ. In vitro activities of ramoplanin, teicoplanin, vancomycin, linezolid, bacitracin, and four other antimicrobials against intestinal anaerobic bacteria. Antimicrob Agents Chemother. 2003;47(7): 2334-2338.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, Issue.7
, pp. 2334-2338
-
-
Citron, D.M.1
Merriam, C.V.2
Tyrrell, K.L.3
Warren, Y.A.4
Fernandez, H.5
Goldstein, E.J.6
-
65
-
-
84941818386
-
Oral bacitracin vs vancomycin therapy for Clostridium difficile-induced diarrhea. A randomized double-blind trial
-
Dudley MN, McLaughlin JC, Carrington G, Frick J, Nightingale CH, Quintiliani R. Oral bacitracin vs vancomycin therapy for Clostridium difficile-induced diarrhea. A randomized double-blind trial. Arch Intern Med. 1986;146(6):1101-1104.
-
(1986)
Arch Intern Med
, vol.146
, Issue.6
, pp. 1101-1104
-
-
Dudley, M.N.1
McLaughlin, J.C.2
Carrington, G.3
Frick, J.4
Nightingale, C.H.5
Quintiliani, R.6
-
66
-
-
79960822735
-
Tigecycline for the treatment of severe Clostridium difficile infection
-
Larson KC, Belliveau PP, Spooner LM. Tigecycline for the treatment of severe Clostridium difficile infection. Ann Pharmacother. 2011; 45(7-8):1005-1010.
-
(2011)
Ann Pharmacother
, vol.45
, Issue.7-8
, pp. 1005-1010
-
-
Larson, K.C.1
Belliveau, P.P.2
Spooner, L.M.3
-
67
-
-
3543083961
-
A double-blind randomized controlled trial of fusidic acid and metronidazole for treatment of an initial episode of Clostridium difficile-associated diarrhoea
-
Wullt M, Odenholt I. A double-blind randomized controlled trial of fusidic acid and metronidazole for treatment of an initial episode of Clostridium difficile-associated diarrhoea. J Antimicrob Chemother. 2004;54(1):211-216.
-
(2004)
J Antimicrob Chemother
, vol.54
, Issue.1
, pp. 211-216
-
-
Wullt, M.1
Odenholt, I.2
-
68
-
-
33748703903
-
Frequent emergence of resistance in Clostridium difficile during treatment of C. difficile-associated diarrhea with fusidic acid
-
Noren T, Wullt M, Akerlund T, Bäck E, Odenholt I, Burman LG. Frequent emergence of resistance in Clostridium difficile during treatment of C. difficile-associated diarrhea with fusidic acid. Antimicrob Agents Chemother. 2006;50(9):3028-3032.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, Issue.9
, pp. 3028-3032
-
-
Noren, T.1
Wullt, M.2
Akerlund, T.3
Bäck, E.4
Odenholt, I.5
Burman, L.G.6
-
69
-
-
17644384052
-
Ramoplanin: A lipoglycodepsipeptide antibiotic
-
Farver DK, Hedge DD, Lee SC. Ramoplanin: a lipoglycodepsipeptide antibiotic. Ann Pharmacother. 2005;39(5):863-868.
-
(2005)
Ann Pharmacother
, vol.39
, Issue.5
, pp. 863-868
-
-
Farver, D.K.1
Hedge, D.D.2
Lee, S.C.3
-
70
-
-
27144453578
-
Comparison of the efficacy of ramoplanin and vancomycin in both in vitro and in vivo models of clindamycin-induced Clostridium difficile infection
-
Freeman J, Baines SD, Jabes D, Wilcox MH. Comparison of the efficacy of ramoplanin and vancomycin in both in vitro and in vivo models of clindamycin-induced Clostridium difficile infection. J Antimicrob Chemother. 2005;56(4):717-725.
-
(2005)
J Antimicrob Chemother
, vol.56
, Issue.4
, pp. 717-725
-
-
Freeman, J.1
Baines, S.D.2
Jabes, D.3
Wilcox, M.H.4
-
72
-
-
84868576303
-
Current and emerging management options for Clostridium difficile infection: What is the role of fidaxomicin?
-
Cornely OA. Current and emerging management options for Clostridium difficile infection: what is the role of fidaxomicin? Clin Microbiol Infect. 2012;18 Suppl 6:28-35.
-
(2012)
Clin Microbiol Infect
, vol.18
, Issue.SUPPL. 6
, pp. 28-35
-
-
Cornely, O.A.1
-
73
-
-
84863673580
-
Current state of Clostridium difficile treatment options
-
Venugopal AA, Johnson S. Current state of Clostridium difficile treatment options. Clin Infect Dis. 2012;55 Suppl 2:S71-S76.
-
(2012)
Clin Infect Dis
, vol.55
, Issue.SUPPL. 2
-
-
Venugopal, A.A.1
Johnson, S.2
-
74
-
-
84861163797
-
Activity of a novel cyclic lipopeptide, CB-183,315, against resistant Clostridium difficile and other Gram-positive aerobic and anaerobic intestinal pathogens
-
Snydman DR, Jacobus NV, McDermott LA. Activity of a novel cyclic lipopeptide, CB-183,315, against resistant Clostridium difficile and other Gram-positive aerobic and anaerobic intestinal pathogens. Antimicrob Agents Chemother. 2012;56(6):3448-3452.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.6
, pp. 3448-3452
-
-
Snydman, D.R.1
Jacobus, N.V.2
McDermott, L.A.3
-
75
-
-
84866313208
-
In vitro and in vivo characterization of CB-183,315, a novel lipopeptide antibiotic for treatment of Clostridium difficile
-
Mascio CT, Mortin LI, Howland KT, et al. In vitro and in vivo characterization of CB-183,315, a novel lipopeptide antibiotic for treatment of Clostridium difficile. Antimicrob Agents Chemother. 2012;56(10): 5023-5030.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.10
, pp. 5023-5030
-
-
Mascio, C.T.1
Mortin, L.I.2
Howland, K.T.3
-
76
-
-
79954582154
-
Evidence of intravenous immunoglobulin as a critical supportive therapy against Clostridium difficile toxin-mediated lethality in mice
-
Saito T, Kimura S, Tateda K, et al. Evidence of intravenous immunoglobulin as a critical supportive therapy against Clostridium difficile toxin-mediated lethality in mice. J Antimicrob Chemother. 2011;66(5): 1096-1099.
-
(2011)
J Antimicrob Chemother
, vol.66
, Issue.5
, pp. 1096-1099
-
-
Saito, T.1
Kimura, S.2
Tateda, K.3
-
77
-
-
2442705389
-
Descriptive study of intravenous immunoglobulin for the treatment of recurrent Clostridium difficile diarrhoea
-
Wilcox MH. Descriptive study of intravenous immunoglobulin for the treatment of recurrent Clostridium difficile diarrhoea. J Antimicrob Chemother. 2004;53(5):882-884.
-
(2004)
J Antimicrob Chemother
, vol.53
, Issue.5
, pp. 882-884
-
-
Wilcox, M.H.1
-
78
-
-
33847150865
-
Clinical outcomes of intravenous immune globulin in severe clostridium difficile-associated diarrhea
-
Juang P, Skledar SJ, Zgheib NK, et al. Clinical outcomes of intravenous immune globulin in severe clostridium difficile-associated diarrhea. Am J Infect Control. 2007;35(2):131-137.
-
(2007)
Am J Infect Control
, vol.35
, Issue.2
, pp. 131-137
-
-
Juang, P.1
Skledar, S.J.2
Zgheib, N.K.3
-
79
-
-
0025727765
-
Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin
-
Leung DY, Kelly CP, Boguniewicz M, Pothoulakis C, LaMont JT, Flores A. Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin. J Pediatr. 1991;118(4 Pt 1):633-637.
-
(1991)
J Pediatr
, vol.118
, Issue.4 PART 1
, pp. 633-637
-
-
Leung, D.Y.1
Kelly, C.P.2
Boguniewicz, M.3
Pothoulakis, C.4
Lamont, J.T.5
Flores, A.6
-
80
-
-
79151476267
-
Intravenous immunoglobulin for the treatment of Clostridium difficile infection: A review
-
Abougergi MS, Kwon JH. Intravenous immunoglobulin for the treatment of Clostridium difficile infection: a review. Dig Dise Sci. 2011; 56(1):19-26.
-
(2011)
Dig Dise Sci
, vol.56
, Issue.1
, pp. 19-26
-
-
Abougergi, M.S.1
Kwon, J.H.2
-
81
-
-
74849098405
-
Treatment with monoclonal antibodies against Clostridium difficile toxins
-
Lowy I, Molrine DC, Leav BA, et al. Treatment with monoclonal antibodies against Clostridium difficile toxins. New Engl J Med. 2010;362(3):197-205.
-
(2010)
New Engl J Med
, vol.362
, Issue.3
, pp. 197-205
-
-
Lowy, I.1
Molrine, D.C.2
Leav, B.A.3
-
82
-
-
84879952042
-
-
ClinicalTrials.gov. A study of MK-3415, MK-6072, and MK-3415A in participants receiving antibiotic therapy for Clostridium difficile infection (MK-3415A-001 AM2) (MODIFY I). ClinicalTrials.gov; 2013. Available from, Accessed April 29, 2013
-
ClinicalTrials.gov. A study of MK-3415, MK-6072, and MK-3415A in participants receiving antibiotic therapy for Clostridium difficile infection (MK-3415A-001 AM2) (MODIFY I). ClinicalTrials.gov; 2013. Available from: http://www.clinicaltrials.gov/ct2/show/NCT01241552. Accessed April 29, 2013.
-
-
-
-
83
-
-
84879907361
-
-
ClinicalTrials.gov. A study of MK-6072 and MK-3415A in participants receiving antibiotic therapy for Clostridium difficile infection (MK-3415A-002) (MODIFY II). ClinicalTrials.gov; 2013. Available from, Accessed April 29, 2013
-
ClinicalTrials.gov. A study of MK-6072 and MK-3415A in participants receiving antibiotic therapy for Clostridium difficile infection (MK-3415A-002) (MODIFY II). ClinicalTrials.gov; 2013. Available from: http://www.clinicaltrials.gov/ct2/show/NCT01513239. Accessed April 29, 2013.
-
-
-
-
84
-
-
79953206941
-
Neutralization of Clostridium difficile toxin A with single-domain antibodies targeting the cell receptor binding domain
-
Hussack G, Arbabi-Ghahroudi M, van Faassen H, et al. Neutralization of Clostridium difficile toxin A with single-domain antibodies targeting the cell receptor binding domain. J Biol Chem. 2011;286(11): 8961-8976.
-
(2011)
J Biol Chem
, vol.286
, Issue.11
, pp. 8961-8976
-
-
Hussack, G.1
Arbabi-Ghahroudi, M.2
van Faassen, H.3
-
85
-
-
3042511702
-
Bacteriotherapy using fecal flora: Toying with human motions
-
Borody TJ, Warren EF, Leis SM, Surace R, Ashman O, Siarakas S. Bacteriotherapy using fecal flora: toying with human motions. J Clin Gastroenterol. 2004;38(6):475-483.
-
(2004)
J Clin Gastroenterol
, vol.38
, Issue.6
, pp. 475-483
-
-
Borody, T.J.1
Warren, E.F.2
Leis, S.M.3
Surace, R.4
Ashman, O.5
Siarakas, S.6
-
86
-
-
84872236149
-
Clostridium difficile infection: New insights into management
-
Khanna S, Pardi DS. Clostridium difficile infection: new insights into management. Mayo Clin Proc. 2012;87(11):1106-1117.
-
(2012)
Mayo Clin Proc
, vol.87
, Issue.11
, pp. 1106-1117
-
-
Khanna, S.1
Pardi, D.S.2
-
87
-
-
82955233474
-
For Fecal Microbiota Transplantation Workgroup. Treating Clostridium difficile infection with fecal microbiota transplantation
-
Bakken JS, Borody T, Brandt LJ, et al; For Fecal Microbiota Transplantation Workgroup. Treating Clostridium difficile infection with fecal microbiota transplantation. Clin Gastroenterol Hepatol. 2011;9(12): 1044-1049.
-
(2011)
Clin Gastroenterol Hepatol
, vol.9
, Issue.12
, pp. 1044-1049
-
-
Bakken, J.S.1
Borody, T.2
Brandt, L.J.3
-
88
-
-
80054736926
-
Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection
-
Gough E, Shaikh H, Manges AR. Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection. Clin Infect Dis. 2011;53(10):994-1002.
-
(2011)
Clin Infect Dis
, vol.53
, Issue.10
, pp. 994-1002
-
-
Gough, E.1
Shaikh, H.2
Manges, A.R.3
-
89
-
-
84873019302
-
Duodenal infusion of donor feces for recurrent Clostridium difficile
-
van Nood E, Vrieze A, Nieuwdorp M, et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med. 2013;368(5): 407-415.
-
(2013)
N Engl J Med
, vol.368
, Issue.5
, pp. 407-415
-
-
van Nood, E.1
Vrieze, A.2
Nieuwdorp, M.3
-
90
-
-
84861201441
-
Meta-analysis: Probiotics in antibiotic-associated diarrhoea
-
Videlock EJ, Cremonini F. Meta-analysis: probiotics in antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2012;35(12): 1355-1369.
-
(2012)
Aliment Pharmacol Ther
, vol.35
, Issue.12
, pp. 1355-1369
-
-
Videlock, E.J.1
Cremonini, F.2
-
91
-
-
84867949871
-
The role of probiotics in the prevention and treatment of antibiotic-associated diarrhea and Clostridium difficile colitis
-
Friedman G. The role of probiotics in the prevention and treatment of antibiotic-associated diarrhea and Clostridium difficile colitis. Gastroenterol Clin North Am. 2012;41(4):763-779.
-
(2012)
Gastroenterol Clin North Am
, vol.41
, Issue.4
, pp. 763-779
-
-
Friedman, G.1
-
92
-
-
84871349683
-
Probiotics for the prevention of Clostridium difficile-associated diarrhea: A systematic review and meta-analysis
-
Johnston BC, Ma SS, Goldenberg JZ, et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis. Ann Intern Med. 2012;157(12):878-888.
-
(2012)
Ann Intern Med
, vol.157
, Issue.12
, pp. 878-888
-
-
Johnston, B.C.1
Ma, S.S.2
Goldenberg, J.Z.3
-
93
-
-
84860708876
-
Probiotics for the prevention and treatment of antibiotic-associated diarrhea: A systematic review and meta-analysis
-
Hempel S, Newberry SJ, Maher AR, et al. Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA. 2012;307(18):1959-1969.
-
(2012)
JAMA
, vol.307
, Issue.18
, pp. 1959-1969
-
-
Hempel, S.1
Newberry, S.J.2
Maher, A.R.3
-
94
-
-
84861975931
-
Clostridium difficile: Development of a novel candidate vaccine
-
Foglia G, Shah S, Luxemburger C, Pietrobon PJ. Clostridium difficile: development of a novel candidate vaccine. Vaccine. 2012;30(29): 4307-4309.
-
(2012)
Vaccine
, vol.30
, Issue.29
, pp. 4307-4309
-
-
Foglia, G.1
Shah, S.2
Luxemburger, C.3
Pietrobon, P.J.4
-
96
-
-
84879941673
-
-
ClinicalTrials.gov. Study of a Clostridium difficile toxoid vaccine (ACAM-CDIFFTM) in subjects with Clostridium difficile infection [webpage on the Internet]. ClinicalTrials.gov; 2012. Available from, Accessed April 29, 2013
-
ClinicalTrials.gov. Study of a Clostridium difficile toxoid vaccine (ACAM-CDIFFTM) in subjects with Clostridium difficile infection [webpage on the Internet]. ClinicalTrials.gov; 2012. Available from: http://www.clinicaltrials.gov/ct2/show/NCT00772343. Accessed April 29, 2013.
-
-
-
-
98
-
-
79851474622
-
First synthesis of C. difficile PS-II cell wall polysaccharide repeating unit
-
Danieli E, Lay L, Proietti D, Berti F, Costantino P, Adamo R. First synthesis of C. difficile PS-II cell wall polysaccharide repeating unit. Org Lett. 2011;13(3):378-381.
-
(2011)
Org Lett
, vol.13
, Issue.3
, pp. 378-381
-
-
Danieli, E.1
Lay, L.2
Proietti, D.3
Berti, F.4
Costantino, P.5
Adamo, R.6
-
99
-
-
79957532830
-
A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic
-
Oberli MA, Hecht ML, Bindschädler P, Adibekian A, Adam T, Seeberger PH. A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic. Chem Biol. 2011;18(5):580-588.
-
(2011)
Chem Biol
, vol.18
, Issue.5
, pp. 580-588
-
-
Oberli, M.A.1
Hecht, M.L.2
Bindschädler, P.3
Adibekian, A.4
Adam, T.5
Seeberger, P.H.6
-
100
-
-
62249140918
-
New approach to the management of Clostridium difficile infection: Colonisation with non-toxigenic C. difficile during daily ampicillin or ceftriaxone administration
-
Merrigan MM, Sambol SP, Johnson S, Gerding DN. New approach to the management of Clostridium difficile infection: colonisation with non-toxigenic C. difficile during daily ampicillin or ceftriaxone administration. Int J Antimicrob Agents. 2009;33 Suppl 1:S46-S50.
-
Int J Antimicrob Agents. 2009;33 Suppl
, vol.1
-
-
Merrigan, M.M.1
Sambol, S.P.2
Johnson, S.3
Gerding, D.N.4
-
101
-
-
84879982940
-
-
ClinicalTrials.gov. Safety and efficacy of VP20621 for prevention of recurrent Clostridium difficile infection [webpage on the Internet]. ClinicalTrials.gov; 2012. Available from, Accessed April 29, 2013
-
ClinicalTrials.gov. Safety and efficacy of VP20621 for prevention of recurrent Clostridium difficile infection [webpage on the Internet]. ClinicalTrials.gov; 2012. Available from: http://www.clinicaltrials.gov/ct2/show/NCT01259726. Accessed April 29, 2013.
-
-
-
-
102
-
-
84863676557
-
Treatment of first recurrence of Clostridium difficile infection: Fidaxomicin versus vancomycin. Clinical infectious diseases: An official publication of the Infectious Diseases Society of America
-
Cornely OA, Miller MA, Louie TJ, et al. Treatment of first recurrence of Clostridium difficile infection: fidaxomicin versus vancomycin. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. Aug 2012;55 Suppl 2:S154-161.
-
(2012)
Aug
, vol.55
, Issue.SUPPL. 2
-
-
Cornely, O.A.1
Miller, M.A.2
Louie, T.J.3
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