메뉴 건너뛰기




Volumn 126, Issue 10, 2013, Pages 2135-2140

Notch signaling at a glance

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ANKYRIN; EPIDERMAL GROWTH FACTOR; GAMMA SECRETASE; GLYCAN; GLYCOGEN SYNTHASE KINASE 3; GLYCOSYLPHOSPHATIDYLINOSITOL; HISTONE DEACETYLASE; JAGGED1; METALLOPROTEINASE; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; PHOSPHOLIPID BINDING PROTEIN;

EID: 84879870498     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.127308     Document Type: Article
Times cited : (442)

References (91)
  • 2
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: cell fate control and signal integration in development
    • Artavanis-Tsakonas, S., Rand, M. D. and Lake, R. J. (1999). Notch signaling: cell fate control and signal integration in development. Science 284, 770-776.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 3
    • 71449126526 scopus 로고    scopus 로고
    • Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions
    • Babaoglan, A. B., O'Connor-Giles, K. M., Mistry, H., Schickedanz, A., Wilson, B. A. and Skeath, J. B. (2009). Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions. Development 136, 4089-4098.
    • (2009) Development , vol.136 , pp. 4089-4098
    • Babaoglan, A.B.1    O'Connor-Giles, K.M.2    Mistry, H.3    Schickedanz, A.4    Wilson, B.A.5    Skeath, J.B.6
  • 4
    • 0036682974 scopus 로고    scopus 로고
    • Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless
    • Barolo, S., Stone, T., Bang, A. G. and Posakony, J. W. (2002). Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless. Genes Dev. 16, 1964- 1976.
    • (2002) Genes Dev. , vol.16
    • Barolo, S.1    Stone, T.2    Bang, A.G.3    Posakony, J.W.4
  • 5
    • 84861988042 scopus 로고    scopus 로고
    • Endocytic routes to Notch activation
    • Baron, M. (2012). Endocytic routes to Notch activation. Semin. Cell Dev. Biol. 23, 437-442.
    • (2012) Semin. Cell Dev. Biol. , vol.23 , pp. 437-442
    • Baron, M.1
  • 6
    • 79151469765 scopus 로고    scopus 로고
    • AP-1 controls the trafficking of Notch and Sanpodo toward E-cadherin junctions in sensory organ precursors
    • Benhra, N., Lallet, S., Cotton, M., Le Bras, S., Dussert, A. and Le Borgne, R. (2011). AP-1 controls the trafficking of Notch and Sanpodo toward E-cadherin junctions in sensory organ precursors. Curr. Biol. 21, 87- 95.
    • (2011) Curr. Biol. , vol.21
    • Benhra, N.1    Lallet, S.2    Cotton, M.3    Le Bras, S.4    Dussert, A.5    Le Borgne, R.6
  • 7
    • 0036696444 scopus 로고    scopus 로고
    • The endocytic protein alpha- Adaptin is required for numb-mediated asymmetric cell division in Drosophila
    • Berdnik, D., Török, T., González-Gaitán, M. and Knoblich, J. A. (2002). The endocytic protein alpha- Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev. Cell 3, 221-231.
    • (2002) Dev. Cell , vol.3 , pp. 221-231
    • Berdnik, D.1    Török, T.2    González-Gaitán, M.3    Knoblich, J.A.4
  • 8
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: a simple pathway becomes complex
    • Bray, S. J. (2006). Notch signalling: a simple pathway becomes complex. Nat. Rev. Mol. Cell Biol. 7, 678-689.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 9
    • 77956309916 scopus 로고    scopus 로고
    • Notch targets and their regulation
    • Bray, S. and Bernard, F. (2010). Notch targets and their regulation. Curr. Top. Dev. Biol. 92, 253-275.
    • (2010) Curr. Top. Dev. Biol. , vol.92 , pp. 253-275
    • Bray, S.1    Bernard, F.2
  • 11
    • 47949097215 scopus 로고    scopus 로고
    • Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
    • Carlson, M. E., Hsu, M. and Conboy, I. M. (2008). Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature 454, 528-532.
    • (2008) Nature , vol.454 , pp. 528-532
    • Carlson, M.E.1    Hsu, M.2    Conboy, I.M.3
  • 12
    • 33750940206 scopus 로고    scopus 로고
    • Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis
    • Childress, J. L., Acar, M., Tao, C. and Halder, G. (2006). Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis. Curr. Biol. 16, 2228-2233.
    • (2006) Curr. Biol. , vol.16 , pp. 2228-2233
    • Childress, J.L.1    Acar, M.2    Tao, C.3    Halder, G.4
  • 13
    • 84863012561 scopus 로고    scopus 로고
    • Conformational locking upon cooperative assembly of notch transcription complexes
    • Choi, S. H., Wales, T. E., Nam, Y., O'Donovan, D. J., Sliz, P., Engen, J. R. and Blacklow, S. C. (2012). Conformational locking upon cooperative assembly of notch transcription complexes. Structure 20, 340-349.
    • (2012) Structure , vol.20 , pp. 340-349
    • Choi, S.H.1    Wales, T.E.2    Nam, Y.3    O'Donovan, D.J.4    Sliz, P.5    Engen, J.R.6    Blacklow, S.C.7
  • 15
    • 0036744815 scopus 로고    scopus 로고
    • The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis
    • Conboy, I. M. and Rando, T. A. (2002). The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Dev. Cell. 3, 397-409.
    • (2002) Dev. Cell. , vol.3 , pp. 397-409
    • Conboy, I.M.1    Rando, T.A.2
  • 16
    • 0344827208 scopus 로고    scopus 로고
    • Notch-mediated restoration of regenerative potential to aged muscle
    • Conboy, I. M., Conboy, M. J., Smythe, G. M. and Rando, T. A. (2003). Notch-mediated restoration of regenerative potential to aged muscle. Science 302, 1575-1577.
    • (2003) Science , vol.302 , pp. 1575-1577
    • Conboy, I.M.1    Conboy, M.J.2    Smythe, G.M.3    Rando, T.A.4
  • 17
    • 67349204759 scopus 로고    scopus 로고
    • Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division
    • Coumailleau, F., Fürthauer, M., Knoblich, J. A. and González-Gaitán, M. (2009). Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division. Nature 458, 1051-1055.
    • (2009) Nature , vol.458 , pp. 1051-1055
    • Coumailleau, F.1    Fürthauer, M.2    Knoblich, J.A.3    González-Gaitán, M.4
  • 20
    • 79251523519 scopus 로고    scopus 로고
    • Mechanism and significance of cis-inhibition in Notch signalling
    • del á lamo, D., Rouault, H. and Schweisguth, F. (2011). Mechanism and significance of cis-inhibition in Notch signalling. Curr. Biol. 21, R40-R47.
    • (2011) Curr. Biol. , vol.21
    • delálamo, D.1    Rouault, H.2    Schweisguth, F.3
  • 21
    • 24144503375 scopus 로고    scopus 로고
    • Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system
    • Emery, G., Hutterer, A., Berdnik, D., Mayer, B., Wirtz-Peitz, F., Gaitan, M. G. and Knoblich, J. A. (2005). Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell 122, 763-773.
    • (2005) Cell , vol.122 , pp. 763-773
    • Emery, G.1    Hutterer, A.2    Berdnik, D.3    Mayer, B.4    Wirtz-Peitz, F.5    Gaitan, M.G.6    Knoblich, J.A.7
  • 22
    • 0041856097 scopus 로고    scopus 로고
    • Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways
    • Espinosa, L., Inglés-Esteve, J., Aguilera, C. and Bigas, A. (2003). Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways. J. Biol. Chem. 278, 32227-32235.
    • (2003) J. Biol. Chem. , vol.278 , pp. 32227-32235
    • Espinosa, L.1    Inglés-Esteve, J.2    Aguilera, C.3    Bigas, A.4
  • 23
    • 34748851341 scopus 로고    scopus 로고
    • Cell and molecular biology of Notch
    • Fiúza, U. M. and Arias, A. M. (2007). Cell and molecular biology of Notch. J. Endocrinol. 194, 459-474.
    • (2007) J. Endocrinol. , vol.194 , pp. 459-474
    • Fiúza, U.M.1    Arias, A.M.2
  • 24
    • 65549121943 scopus 로고    scopus 로고
    • Notch signaling: the core pathway and its posttranslational regulation
    • Fortini, M. E. (2009). Notch signaling: the core pathway and its posttranslational regulation. Dev. Cell 16, 633-647.
    • (2009) Dev. Cell , vol.16 , pp. 633-647
    • Fortini, M.E.1
  • 25
    • 80455155120 scopus 로고    scopus 로고
    • Notch signaling in intestinal homeostasis across species: the cases of Drosophila, Zebrafish and the mouse
    • Fre, S., Bardin, A., Robine, S. and Louvard, D. (2011). Notch signaling in intestinal homeostasis across species: the cases of Drosophila, Zebrafish and the mouse. Exp. Cell Res. 317, 2740-2747.
    • (2011) Exp. Cell Res. , vol.317 , pp. 2740-2747
    • Fre, S.1    Bardin, A.2    Robine, S.3    Louvard, D.4
  • 26
    • 8844229536 scopus 로고    scopus 로고
    • Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover
    • Fryer, C. J., White, J. B. and Jones, K. A. (2004). Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol. Cell 16, 509-520.
    • (2004) Mol. Cell , vol.16 , pp. 509-520
    • Fryer, C.J.1    White, J.B.2    Jones, K.A.3
  • 27
    • 33750479395 scopus 로고    scopus 로고
    • The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila
    • Gallagher, C. M. and Knoblich, J. A. (2006). The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila. Dev. Cell 11, 641-653.
    • (2006) Dev. Cell , vol.11 , pp. 641-653
    • Gallagher, C.M.1    Knoblich, J.A.2
  • 28
    • 33644753146 scopus 로고    scopus 로고
    • Nipped-A, the Tra1/TRRAP subunit of the Drosophila SAGA and Tip60 complexes, has multiple roles in Notch signaling during wing development
    • Gause, M., Eissenberg, J. C., Macrae, A. F., Dorsett, M., Misulovin, Z. and Dorsett, D. (2006). Nipped-A, the Tra1/TRRAP subunit of the Drosophila SAGA and Tip60 complexes, has multiple roles in Notch signaling during wing development. Mol. Cell. Biol. 26, 2347-2359.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2347-2359
    • Gause, M.1    Eissenberg, J.C.2    Macrae, A.F.3    Dorsett, M.4    Misulovin, Z.5    Dorsett, D.6
  • 29
    • 55449135598 scopus 로고    scopus 로고
    • The molecular logic of Notch signalling - a structural and biochemical perspective
    • Gordon, W. R., Arnett, K. L. and Blacklow, S. C. (2008). The molecular logic of Notch signalling - a structural and biochemical perspective. J. Cell Sci. 121, 3109-3119.
    • (2008) J. Cell Sci. , vol.121 , pp. 3109-3119
    • Gordon, W.R.1    Arnett, K.L.2    Blacklow, S.C.3
  • 30
    • 0032525964 scopus 로고    scopus 로고
    • LIN-12/Notch signaling: lessons from worms and flies
    • Greenwald, I. (1998). LIN-12/Notch signaling: lessons from worms and flies. Genes Dev. 12, 1751-1762.
    • (1998) Genes Dev. , vol.12 , pp. 1751-1762
    • Greenwald, I.1
  • 31
    • 0037390535 scopus 로고    scopus 로고
    • Notch signaling and inherited disease syndromes
    • Gridley, T. (2003). Notch signaling and inherited disease syndromes. Hum. Mol. Genet. 12 Spec. No 1, R9-R13.
    • (2003) Hum. Mol. Genet. 12 Spec. No , vol.1
    • Gridley, T.1
  • 32
    • 0035860804 scopus 로고    scopus 로고
    • Functional interaction between SEL-10, an Fbox protein, and the nuclear form of activated Notch1 receptor
    • Gupta-Rossi, N., Le Bail, O., Gonen, H., Brou, C., Logeat, F., Six, E., Ciechanover, A. and Israël, A. (2001). Functional interaction between SEL-10, an Fbox protein, and the nuclear form of activated Notch1 receptor. J. Biol. Chem. 276, 34371-34378.
    • (2001) J. Biol. Chem. , vol.276 , pp. 34371-34378
    • Gupta-Rossi, N.1    Le Bail, O.2    Gonen, H.3    Brou, C.4    Logeat, F.5    Six, E.6    Ciechanover, A.7    Israël, A.8
  • 33
    • 84865241459 scopus 로고    scopus 로고
    • The Notch signalling system: recent insights into the complexity of a conserved pathway
    • Guruharsha, K. G., Kankel, M. W. and Artavanis- Tsakonas, S. (2012). The Notch signalling system: recent insights into the complexity of a conserved pathway. Nat. Rev. Genet. 13, 654-666.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 654-666
    • Guruharsha, K.G.1    Kankel, M.W.2    Artavanis-Tsakonas, S.3
  • 35
    • 10344263367 scopus 로고    scopus 로고
    • Drosophila deltex mediates suppressor of Hairlessindependent and late-endosomal activation of Notch signaling
    • Hori, K., Fostier, M., Ito, M., Fuwa, T. J., Go, M. J., Okano, H., Baron, M. and Matsuno, K. (2004). Drosophila deltex mediates suppressor of Hairlessindependent and late-endosomal activation of Notch signaling. Development 131, 5527-5537.
    • (2004) Development , vol.131 , pp. 5527-5537
    • Hori, K.1    Fostier, M.2    Ito, M.3    Fuwa, T.J.4    Go, M.J.5    Okano, H.6    Baron, M.7    Matsuno, K.8
  • 36
    • 15044352019 scopus 로고    scopus 로고
    • Genetic regions that interact with loss- and gain-offunction phenotypes of deltex implicate novel genes in Drosophila Notch signaling
    • Hori, K., Fuwa, T. J., Seki, T. and Matsuno, K. (2005). Genetic regions that interact with loss- and gain-offunction phenotypes of deltex implicate novel genes in Drosophila Notch signaling. Mol. Genet. Genomics 272, 627-638.
    • (2005) Mol. Genet. Genomics , vol.272 , pp. 627-638
    • Hori, K.1    Fuwa, T.J.2    Seki, T.3    Matsuno, K.4
  • 37
    • 84855513161 scopus 로고    scopus 로고
    • Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal
    • Hori, K., Sen, A., Kirchhausen, T. and Artavanis- Tsakonas, S. (2011). Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal. J. Cell Biol. 195, 1005-1015.
    • (2011) J. Cell Biol. , vol.195 , pp. 1005-1015
    • Hori, K.1    Sen, A.2    Kirchhausen, T.3    Artavanis-Tsakonas, S.4
  • 38
    • 0033524444 scopus 로고    scopus 로고
    • CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex
    • Hsieh, J. J., Zhou, S., Chen, L., Young, D. B. and Hayward, S. D. (1999). CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. Proc. Natl. Acad. Sci. USA 96, 23-28.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 23-28
    • Hsieh, J.J.1    Zhou, S.2    Chen, L.3    Young, D.B.4    Hayward, S.D.5
  • 40
    • 30944462650 scopus 로고    scopus 로고
    • Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs
    • Hutterer, A. and Knoblich, J. A. (2005). Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. EMBO Rep. 6, 836-842.
    • (2005) EMBO Rep. , vol.6 , pp. 836-842
    • Hutterer, A.1    Knoblich, J.A.2
  • 41
    • 0035977049 scopus 로고    scopus 로고
    • Phosphorylation of Ser2078 modulates the Notch2 function in 32D cell differentiation
    • Inglés-Esteve, J., Espinosa, L., Milner, L. A., Caelles, C. and Bigas, A. (2001). Phosphorylation of Ser2078 modulates the Notch2 function in 32D cell differentiation. J. Biol. Chem. 276, 44873-44880.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44873-44880
    • Inglés-Esteve, J.1    Espinosa, L.2    Milner, L.A.3    Caelles, C.4    Bigas, A.5
  • 42
    • 33750433236 scopus 로고    scopus 로고
    • The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking
    • Jaekel, R. and Klein, T. (2006). The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking. Dev. Cell 11, 655-669.
    • (2006) Dev. Cell , vol.11 , pp. 655-669
    • Jaekel, R.1    Klein, T.2
  • 43
    • 0037040917 scopus 로고    scopus 로고
    • c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated Notch1
    • Jehn, B. M., Dittert, I., Beyer, S., von der Mark, K. and Bielke, W. (2002). c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated Notch1. J. Biol. Chem. 277, 8033-8040.
    • (2002) J. Biol. Chem. , vol.277 , pp. 8033-8040
    • Jehn, B.M.1    Dittert, I.2    Beyer, S.3    von der Mark, K.4    Bielke, W.5
  • 44
    • 0037291915 scopus 로고    scopus 로고
    • Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes
    • Kadam, S. and Emerson, B. M. (2003). Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes. Mol. Cell 11, 377-389.
    • (2003) Mol. Cell , vol.11 , pp. 377-389
    • Kadam, S.1    Emerson, B.M.2
  • 45
    • 77956328568 scopus 로고    scopus 로고
    • Ultradian oscillations in Notch signaling regulate dynamic biological events
    • Kageyama, R., Niwa, Y., Shimojo, H., Kobayashi, T. and Ohtsuka, T. (2010). Ultradian oscillations in Notch signaling regulate dynamic biological events. Curr. Top Dev. Biol. 92, 311-331.
    • (2010) Curr. Top Dev. Biol. , vol.92 , pp. 311-331
    • Kageyama, R.1    Niwa, Y.2    Shimojo, H.3    Kobayashi, T.4    Ohtsuka, T.5
  • 46
    • 84858822444 scopus 로고    scopus 로고
    • AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in Notch signaling during eye development in Drosophila melanogaster
    • Kametaka, S., Kametaka, A., Yonekura, S., Haruta, M., Takenoshita, S., Goto, S. and Waguri, S. (2012). AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in Notch signaling during eye development in Drosophila melanogaster. J. Cell Sci. 125, 634-648.
    • (2012) J. Cell Sci. , vol.125 , pp. 634-648
    • Kametaka, S.1    Kametaka, A.2    Yonekura, S.3    Haruta, M.4    Takenoshita, S.5    Goto, S.6    Waguri, S.7
  • 47
    • 77956306573 scopus 로고    scopus 로고
    • Notch signaling in solid tumors
    • Koch, U. and Radtke, F. (2010). Notch signaling in solid tumors. Curr. Top. Dev. Biol. 92, 411-455.
    • (2010) Curr. Top. Dev. Biol. , vol.92 , pp. 411-455
    • Koch, U.1    Radtke, F.2
  • 48
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: unfolding the activation mechanism
    • Kopan, R. and Ilagan, M. X. (2009). The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137, 216-233.
    • (2009) Cell , vol.137 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 49
    • 77956300942 scopus 로고    scopus 로고
    • Mechanistic insights into Notch receptor signaling from structural and biochemical studies
    • Kovall, R. A. and Blacklow, S. C. (2010). Mechanistic insights into Notch receptor signaling from structural and biochemical studies. Curr. Top. Dev. Biol. 92, 31-71.
    • (2010) Curr. Top. Dev. Biol. , vol.92 , pp. 31-71
    • Kovall, R.A.1    Blacklow, S.C.2
  • 50
    • 18844452750 scopus 로고    scopus 로고
    • Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.
    • Le Borgne, R., Remaud, S., Hamel, S. and Schweisguth, F. (2005). Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila. PLoS Biol. 3, e96.
    • (2005) PLoS Biol , vol.3
    • Le Borgne, R.1    Remaud, S.2    Hamel, S.3    Schweisguth, F.4
  • 51
    • 77956331142 scopus 로고    scopus 로고
    • Notch signaling in the regulation of stem cell self-renewal and differentiation
    • Liu, J., Sato, C., Cerletti, M. and Wagers, A. (2010). Notch signaling in the regulation of stem cell self-renewal and differentiation. Curr. Top. Dev. Biol. 92, 367-409.
    • (2010) Curr. Top. Dev. Biol. , vol.92 , pp. 367-409
    • Liu, J.1    Sato, C.2    Cerletti, M.3    Wagers, A.4
  • 54
    • 31444452338 scopus 로고    scopus 로고
    • Evidence that stem cells reside in the adult Drosophila midgut epithelium
    • Micchelli, C. A. and Perrimon, N. (2006). Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature 439, 475-479.
    • (2006) Nature , vol.439 , pp. 475-479
    • Micchelli, C.A.1    Perrimon, N.2
  • 56
    • 84861990389 scopus 로고    scopus 로고
    • Notch ligand endocytosis: mechanistic basis of signaling activity
    • Musse, A. A., Meloty-Kapella, L. and Weinmaster, G. (2012). Notch ligand endocytosis: mechanistic basis of signaling activity. Semin. Cell Dev. Biol. 23, 429-436.
    • (2012) Semin. Cell Dev. Biol. , vol.23 , pp. 429-436
    • Musse, A.A.1    Meloty-Kapella, L.2    Weinmaster, G.3
  • 57
    • 27944445286 scopus 로고    scopus 로고
    • Hairlessmediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors
    • Nagel, A. C., Krejci, A., Tenin, G., Bravo-Patiño, A., Bray, S., Maier, D. and Preiss, A. (2005). Hairlessmediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors. Mol. Cell. Biol. 25, 10433-10441.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 10433-10441
    • Nagel, A.C.1    Krejci, A.2    Tenin, G.3    Bravo-Patiño, A.4    Bray, S.5    Maier, D.6    Preiss, A.7
  • 58
    • 31444444485 scopus 로고    scopus 로고
    • The adult Drosophila posterior midgut is maintained by pluripotent stem cells
    • Ohlstein, B. and Spradling, A. (2006). The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature 439, 470-474.
    • (2006) Nature , vol.439 , pp. 470-474
    • Ohlstein, B.1    Spradling, A.2
  • 59
    • 33847168133 scopus 로고    scopus 로고
    • Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling
    • Ohlstein, B. and Spradling, A. (2007). Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling. Science 315, 988- 992.
    • (2007) Science , vol.315
    • Ohlstein, B.1    Spradling, A.2
  • 60
    • 0037074006 scopus 로고    scopus 로고
    • Regulation of notch signaling by o-linked fucose
    • Okajima, T. and Irvine, K. D. (2002). Regulation of notch signaling by o-linked fucose. Cell 111, 893-904.
    • (2002) Cell , vol.111 , pp. 893-904
    • Okajima, T.1    Irvine, K.D.2
  • 61
    • 14844355836 scopus 로고    scopus 로고
    • Chaperone activity of protein O-fucosyltransferase 1 promotes notch receptor folding
    • Okajima, T., Xu, A., Lei, L. and Irvine, K. D. (2005). Chaperone activity of protein O-fucosyltransferase 1 promotes notch receptor folding. Science 307, 1599-1603.
    • (2005) Science , vol.307 , pp. 1599-1603
    • Okajima, T.1    Xu, A.2    Lei, L.3    Irvine, K.D.4
  • 63
    • 84863846777 scopus 로고    scopus 로고
    • Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila
    • Pallavi, S. K., Ho, D. M., Hicks, C., Miele, L. and Artavanis-Tsakonas, S. (2012). Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila. EMBO J. 31, 2895-2907.
    • (2012) EMBO J. , vol.31 , pp. 2895-2907
    • Pallavi, S.K.1    Ho, D.M.2    Hicks, C.3    Miele, L.4    Artavanis-Tsakonas, S.5
  • 66
    • 84872502135 scopus 로고    scopus 로고
    • Sending the right signal: Notch and stem cells
    • Perdigoto, C. N. and Bardin, A. J. (2013). Sending the right signal: Notch and stem cells. Biochim. Biophys. Acta 1830, 2307-2322.
    • (2013) Biochim. Biophys. Acta , vol.1830 , pp. 2307-2322
    • Perdigoto, C.N.1    Bardin, A.J.2
  • 67
    • 80052700259 scopus 로고    scopus 로고
    • Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine
    • Perdigoto, C. N., Schweisguth, F. and Bardin, A. J. (2011). Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine. Development 138, 4585-4595.
    • (2011) Development , vol.138 , pp. 4585-4595
    • Perdigoto, C.N.1    Schweisguth, F.2    Bardin, A.J.3
  • 68
    • 80053570445 scopus 로고    scopus 로고
    • Fringe benefits: functional and structural impacts of Oglycosylation on the extracellular domain of Notch receptors
    • Rana, N. A. and Haltiwanger, R. S. (2011). Fringe benefits: functional and structural impacts of Oglycosylation on the extracellular domain of Notch receptors. Curr. Opin. Struct. Biol. 21, 583-589.
    • (2011) Curr. Opin. Struct. Biol. , vol.21 , pp. 583-589
    • Rana, N.A.1    Haltiwanger, R.S.2
  • 69
    • 80052422050 scopus 로고    scopus 로고
    • O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1
    • Rana, N. A., Nita-Lazar, A., Takeuchi, H., Kakuda, S., Luther, K. B. and Haltiwanger, R. S. (2011). O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1. J. Biol. Chem. 286, 31623-31637.
    • (2011) J. Biol. Chem. , vol.286 , pp. 31623-31637
    • Rana, N.A.1    Nita-Lazar, A.2    Takeuchi, H.3    Kakuda, S.4    Luther, K.B.5    Haltiwanger, R.S.6
  • 70
    • 0026086474 scopus 로고
    • Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor
    • Rebay, I., Fleming, R. J., Fehon, R. G., Cherbas, L., Cherbas, P. and Artavanis-Tsakonas, S. (1991). Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell 67, 687-699.
    • (1991) Cell , vol.67 , pp. 687-699
    • Rebay, I.1    Fleming, R.J.2    Fehon, R.G.3    Cherbas, L.4    Cherbas, P.5    Artavanis-Tsakonas, S.6
  • 71
    • 11144350287 scopus 로고    scopus 로고
    • Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation
    • Sakata, T., Sakaguchi, H., Tsuda, L., Higashitani, A., Aigaki, T., Matsuno, K. and Hayashi, S. (2004). Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation. Curr. Biol. 14, 2228-2236.
    • (2004) Curr. Biol. , vol.14 , pp. 2228-2236
    • Sakata, T.1    Sakaguchi, H.2    Tsuda, L.3    Higashitani, A.4    Aigaki, T.5    Matsuno, K.6    Hayashi, S.7
  • 72
    • 34248148020 scopus 로고    scopus 로고
    • The O-fucosyltransferase Ofut1 is an extracellular component that is essential for the constitutive endocytic trafficking of Notch in Drosophila
    • Sasamura, T., Ishikawa, H. O., Sasaki, N., Higashi, S., Kanai, M., Nakao, S., Ayukawa, T., Aigaki, T., Noda, K., Miyoshi, E. et al. (2007). The O-fucosyltransferase Ofut1 is an extracellular component that is essential for the constitutive endocytic trafficking of Notch in Drosophila. Development 134, 1347-1356.
    • (2007) Development , vol.134 , pp. 1347-1356
    • Sasamura, T.1    Ishikawa, H.O.2    Sasaki, N.3    Higashi, S.4    Kanai, M.5    Nakao, S.6    Ayukawa, T.7    Aigaki, T.8    Noda, K.9    Miyoshi, E.10
  • 73
    • 0028342417 scopus 로고
    • Antagonistic activities of Suppressor of Hairless and Hairless control alternative cell fates in the Drosophila adult epidermis
    • Schweisguth, F. and Posakony, J. W. (1994). Antagonistic activities of Suppressor of Hairless and Hairless control alternative cell fates in the Drosophila adult epidermis. Development 120, 1433-1441.
    • (1994) Development , vol.120 , pp. 1433-1441
    • Schweisguth, F.1    Posakony, J.W.2
  • 74
    • 0031573944 scopus 로고    scopus 로고
    • Requirement for dynamin during Notch signaling in Drosophila neurogenesis
    • Seugnet, L., Simpson, P. and Haenlin, M. (1997). Requirement for dynamin during Notch signaling in Drosophila neurogenesis. Dev. Biol. 192, 585-598.
    • (1997) Dev. Biol. , vol.192 , pp. 585-598
    • Seugnet, L.1    Simpson, P.2    Haenlin, M.3
  • 75
    • 84862119187 scopus 로고    scopus 로고
    • Optical tweezers studies on Notch: single-molecule interaction strength is independent of ligand endocytosis
    • Shergill, B., Meloty-Kapella, L., Musse, A. A., Weinmaster, G. and Botvinick, E. (2012). Optical tweezers studies on Notch: single-molecule interaction strength is independent of ligand endocytosis. Dev. Cell 22, 1313-1320.
    • (2012) Dev. Cell , vol.22 , pp. 1313-1320
    • Shergill, B.1    Meloty-Kapella, L.2    Musse, A.A.3    Weinmaster, G.4    Botvinick, E.5
  • 77
    • 0033535508 scopus 로고    scopus 로고
    • Presenilin is required for activity and nuclear access of Notch in Drosophila
    • Struhl, G. and Greenwald, I. (1999). Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398, 522-525.
    • (1999) Nature , vol.398 , pp. 522-525
    • Struhl, G.1    Greenwald, I.2
  • 79
    • 84858118267 scopus 로고    scopus 로고
    • The tumour suppressor Lethal (2) giant discs is required for the function of the ESCRT-III component Shrub/CHMP4
    • Troost, T., Jaeckel, S., Ohlenhard, N. and Klein, T. (2012). The tumour suppressor Lethal (2) giant discs is required for the function of the ESCRT-III component Shrub/CHMP4. J. Cell Sci. 125, 763-776.
    • (2012) J. Cell Sci. , vol.125 , pp. 763-776
    • Troost, T.1    Jaeckel, S.2    Ohlenhard, N.3    Klein, T.4
  • 81
    • 40849114907 scopus 로고    scopus 로고
    • Endosomal entry regulates Notch receptor activation in Drosophila melanogaster
    • Vaccari, T., Lu, H., Kanwar, R., Fortini, M. E. and Bilder, D. (2008). Endosomal entry regulates Notch receptor activation in Drosophila melanogaster. J. Cell Biol. 180, 755-762.
    • (2008) J. Cell Biol. , vol.180 , pp. 755-762
    • Vaccari, T.1    Lu, H.2    Kanwar, R.3    Fortini, M.E.4    Bilder, D.5
  • 82
    • 69649094146 scopus 로고    scopus 로고
    • Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
    • Vaccari, T., Rusten, T. E., Menut, L., Nezis, I. P., Brech, A., Stenmark, H. and Bilder, D. (2009). Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants. J. Cell Sci. 122, 2413-2423.
    • (2009) J. Cell Sci. , vol.122 , pp. 2413-2423
    • Vaccari, T.1    Rusten, T.E.2    Menut, L.3    Nezis, I.P.4    Brech, A.5    Stenmark, H.6    Bilder, D.7
  • 83
    • 0036840497 scopus 로고    scopus 로고
    • p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro
    • Wallberg, A. E., Pedersen, K., Lendahl, U. and Roeder, R. G. (2002). p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro. Mol. Cell. Biol. 22, 7812-7819.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7812-7819
    • Wallberg, A.E.1    Pedersen, K.2    Lendahl, U.3    Roeder, R.G.4
  • 84
    • 9444297354 scopus 로고    scopus 로고
    • Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch
    • Wang, W. and Struhl, G. (2004). Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch. Development 131, 5367- 5380.
    • (2004) Development , vol.131
    • Wang, W.1    Struhl, G.2
  • 85
    • 21644462494 scopus 로고    scopus 로고
    • Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila
    • Wang, W. and Struhl, G. (2005). Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila. Development 132, 2883-2894.
    • (2005) Development , vol.132 , pp. 2883-2894
    • Wang, W.1    Struhl, G.2
  • 88
    • 77956309044 scopus 로고    scopus 로고
    • Endocytosis and intracellular trafficking of Notch and its ligands
    • Yamamoto, S., Charng, W. L. and Bellen, H. J. (2010). Endocytosis and intracellular trafficking of Notch and its ligands. Curr. Top. Dev. Biol. 92, 165-200.
    • (2010) Curr. Top. Dev. Biol. , vol.92 , pp. 165-200
    • Yamamoto, S.1    Charng, W.L.2    Bellen, H.J.3
  • 89
    • 0035726304 scopus 로고    scopus 로고
    • Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex
    • Zhou, S. and Hayward, S. D. (2001). Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex. Mol. Cell. Biol. 21, 6222- 6232.
    • (2001) Mol. Cell. Biol. , vol.21
    • Zhou, S.1    Hayward, S.D.2
  • 90
    • 0034073379 scopus 로고    scopus 로고
    • SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function
    • Zhou, S., Fujimuro, M., Hsieh, J. J., Chen, L., Miyamoto, A., Weinmaster, G. and Hayward, S. D. (2000). SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function. Mol. Cell. Biol. 20, 2400-2410.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2400-2410
    • Zhou, S.1    Fujimuro, M.2    Hsieh, J.J.3    Chen, L.4    Miyamoto, A.5    Weinmaster, G.6    Hayward, S.D.7
  • 91
    • 46449089731 scopus 로고    scopus 로고
    • ADAM proteases: ligand processing and modulation of the Notch pathway
    • Zolkiewska, A. (2008). ADAM proteases: ligand processing and modulation of the Notch pathway. Cell. Mol. Life Sci. 65, 2056-2068.
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 2056-2068
    • Zolkiewska, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.