Ultradian oscillations in Notch signaling regulate dynamic biological events

Current Topics in Developmental Biology

Volumn 92, Issue C, 2010, Pages 311-331

  Kageyama, Ryoichiro ^a   Niwa, Yasutaka ^a   Shimojo, Hiromi ^a   Kobayashi, Taeko ^a   Ohtsuka, Toshiyuki ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR;

ANIMAL; BIOLOGICAL RHYTHM; BOOK; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; MOUSE; PERIODICITY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ACTIVITY CYCLES; ANIMALS; BIOLOGICAL CLOCKS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 77956328568     PISSN: 00702153     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0070-2153(10)92010-3     Document Type: Book

References (64)

1. Alvarez-Buylla A., Garcia-Verdugo J.M., Tramontin A.D. A unified hypothesis on the lineage of neural stem cells. Nat. Rev. Neurosci. 2001, 2:287-293.
2. Artavanis-Tsakonas S., Rand M.D., Lake R.J. Notch signaling: cell fate control and signal integration in development. Science 1999, 284:770-776.
3. Aulehla A., Wiegraebe W., Baubet V., Wahl M.B., Deng C., Taketo M., Lewandoski M., Pourqui O. A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation. Nat. Cell Biol. 2008, 10:186-193.
4. Baek J.H., Hatakeyama J., Sakamoto S., Ohtsuka T., Kageyama R. Persistent and high levels of Hes1 expression regulate boundary formation in the developing central nervous system. Development 2006, 133:2467-2476.
5. Bertrand N., Castro D.S., Guillemot F. Proneural genes and the specification of neural cell types. Nat. Rev. Neurosci. 2002, 3:517-530.
6. Bessho Y., Hirata H., Masamizu Y., Kageyama R. Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock. Genes Dev. 2003, 17:1451-1456.
7. Bessho Y., Miyoshi G., Sakata R., Kageyama R. Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm. Genes Cells 2001, 6:175-185.
8. Bessho Y., Sakata R., Komatsu S., Shiota K., Yamada S., Kageyama R. Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev. 2001, 15:2642-2647.
9. Chambers I., Silva J., Colby D., Nichols J., Nijmeijer B., Robertson M., Vrana J., Jones K., Grotewold L., Smith A. Nanog safeguards pluripotency and mediates germline development. Nature 2007, 450:1230-1234.
10. Dale J.K., Maroto M., Dequeant M.L., Malapert P., McGrew M., Pourqui O. Periodic Notch inhibition by Lunatic Fringe underlies the chick segmentation clock. Nature 2003, 421:275-278.
11. Dawson S.R., Turner D.L., Weintraub H., Parkhurst S.M. Specificity for the hairy/enhancer of split basic helix-loop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repression. Mol. Cell. Biol. 1995, 15:6923-6931.
12. Dequéant M.-L., Glynn E., Gaudenz K., Wahl M., Chen J., Mushegian A., Pourqui O. A complex oscillating network of signaling genes underlies the mouse segmentation clock. Science 2006, 314:1595-1598.
13. Dequéant M.L., Pourqui O. Segmental patterning of the vertebrate embryonic axis. Nat. Rev. Genet. 2008, 9:370-382.
14. Evrard Y.A., Lun Y., Aulehla A., Gan L., Johnson R.L. Lunatic fringe is an essential mediator of somite segmentation and patterning. Nature 1998, 394:377-381.
15. Ferjentsik Z., Hayashi S., Dale J.K., Bessho Y., Herreman A., De Strooper B., del Monte G., de la Pompa J.L., Maroto M. Notch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somites. PLoS Genet. 2009, 5:e1000662.
16. Fishell G., Kriegstein A.R. Neurons from radial glia: the consequences of asymmetric inheritance. Curr. Opin. Neurobiol. 2003, 13:34-41.
17. Fujita S. The discovery of the matrix cell, the identification of the multipotent neural stem cell and the development of the central nervous system. Cell Struct. Funct. 2003, 28:205-228.
18. Hatakeyama J., Bessho Y., Katoh K., Ookawara S., Fujioka M., Guillemot F., Kageyama R. Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation. Development 2004, 131:5539-5550.
19. Heng J.I., Nguyen L., Castro D.S., Zimmer C., Wildner H., Armant O., Skowronska-Krawczyk D., Bedogni F., Matter J.M., Hevner R., Guillemot F. Neurogenin 2 controls cortical neuron migration through regulation of Rnd2. Nature 2008, 455:114-118.
20. Hirata H., Bessho Y., Kokubu H., Masamizu Y., Yamada S., Lewis J., Kageyama R. Instability of Hes7 protein is crucial for the somite segmentation clock. Nat. Genet. 2004, 36:750-754.
21. Hirata H., Yoshiura S., Ohtsuka T., Bessho Y., Harada T., Yoshikawa K., Kageyama R. Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop. Science 2002, 298:840-843.
22. Hoffmann A., Levchenko A., Scott M.L., Baltimore D. The IκB-NF-κB signaling module: temporal control and selective gene activation. Science 2002, 298:1241-1245.
23. Honjo T. The shortest path from the surface to the nucleus: RBP-J κ/Su(H) transcription factor. Genes Cells 1996, 1:1-9.
24. Horikawa K., Ishimatsu K., Yoshimoto E., Kondo S., Takeda H. Noise-resistant and synchronized oscillation of the segmentation clock. Nature 2006, 441:719-723.
25. Huppert S.S., Ilagan M.X.G., De Strooper B., Kopan R. Analysis of Notch function in presomitic mesoderm suggests a γ-secretase-independent role for presenilins in somite differentiation. Dev. Cell 2005, 8:677-688.
26. Ishibashi M., Ang S.L., Shiota K., Nakanishi S., Kageyama R., Guillemot F. Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects. Genes Dev. 1995, 9:3136-3148.
27. Iso T., Kedes L., Hamamori Y. HES and HERP families: multiple effectors of the Notch signaling pathway. J. Cell. Physiol. 2003, 194:237-255.
28. Jang J., Ku S.Y., Kim J.E., et al. Notch inhibition promotes human embryonic stem cell-derived cardiac mesoderm differentiation. Stem Cells 2008, 26:2782-2790.
29. Jensen M.H., Sneppen K., Tiana G. Sustained oscillations and time delays in gene expression of protein Hes1. FEBS Lett. 2003, 541:176-177.
30. Jiang Y.-J., Aerne B.L., Smithers L., Haddon C., Ish-Horowicz D., Lewis J. Notch signaling and the synchronization of the somite segmentation clock. Nature 2000, 408:475-479.
31. Jouve C., Palmeirim I., Henrique D., Beckers J., Gossler A., Ish-Horowicz D., Pourqui O. Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm. Development 2000, 127:1421-1429.
32. Kageyama R., Ohtsuka T., Kobayashi T. The Hes gene family: repressors and oscillators that orchestrate embryogenesis. Development 2007, 134:1243-1251.
33. Kageyama R., Ohtsuka T., Shimojo H., Imayoshi I. Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition. Nat. Neurosci. 2008, 11:1247-1251.
34. Kamakura S., Oishi K., Yoshimatsu T., Nakafuku M., Masuyama N., Gotoh Y. Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signaling. Nat. Cell Biol. 2004, 6:547-554.
35. Kang S.A., Seol J.H., Kim J. The conserved WRPW motif of Hes6 mediates proteasomal degradation. Biochem. Biophys. Res. Commun. 2005, 332:33-36.
36. Kiecker C., Lumsden A. Compartments and their boundaries in vertebrate brain development. Nat. Rev. Neurosci. 2005, 6:553-564.
37. Kobayashi T., Mizuno H., Imayoshi I., Furusawa C., Shirahige K., Kageyama R. The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells. Genes Dev. 2009, 23:1870-1875.
38. Kobayashi T., Kageyama R. Hes1 regulates embryonic stem cell differentiation by suppressing Notch signaling. Genes Cells 2010, in press.
39. Kopan R., Ilagan M.X.G. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 2009, 137:216-233.
40. Lahav G., Rosenfeld N., Sigal A., Geva-Zatorsky N., Levine A.J., Elowitz M.B., Alon U. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat. Genet. 2004, 36:147-150.
41. Lewis J. Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator. Curr. Biol. 2003, 13:1398-1408.
42. Lowell S., Benchoua A., Heavey B., Smith A.G. Notch promotes neural lineage entry by pluripotent embryonic stem cells. PLoS Biol. 2006, 4:805-818.
43. Mara A., Holley S.A. Oscillators and the emergence of tissue organization during zebrafish somitogenesis. Trends Cell Biol. 2007, 17:593-599.
44. Maroto M., Dale J.K., Dequéant M.-L., Petit A.-C., Pourqui O. Synchronised cycling gene oscillations in presomitic mesoderm cells require cell-cell contact. Int. J. Dev. Biol. 2005, 49:309-315.
45. Masamizu Y., Ohtsuka T., Takashima Y., Nagahara H., Takenaka Y., Yoshikawa K., Okamura H., Kageyama R. Real-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:1313-1318.
46. Monk N.A.M. Oscillatory expression of Hes1, p53, and NF-κB driven by transcriptional time delays. Curr. Biol. 2003, 13:1409-1413.
47. Morimoto M., Takahashi Y., Endo M., Saga Y. The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature 2005, 435:354-359.
48. Nakayama K., Satoh T., Igari A., Kageyama R., Nishida E. FGF induces oscillations of Hes1 expression and Ras/ERK activation. Curr. Biol. 2008, 18:R332-R334.
49. Nemir M., Croquelois A., Pedrazzini T., Radtke F. Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling. Circ. Res. 2006, 98:1471-1478.
50. Niwa Y., Masamizu Y., Liu T., Nakayama R., Deng C.-X., Kageyama R. The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and Notch signaling in the somite segmentation clock. Dev. Cell 2007, 13:298-304.
51. Ohtsuka T., Ishibashi M., Gradwohl G., Nakanishi S., Guillemot F., Kageyama R. Hes1 and Hes5 as Notch effectors in mammalian neuronal differentiation. EMBO J. 1999, 18:2196-2207.
52. Ohtsuka T., Sakamoto M., Guillemot F., Kageyama R. Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain. J. Biol. Chem. 2001, 276:30467-30474.
53. Pourqui O. The segmentation clock: converting embryonic time into spatial pattern. Science 2003, 301:328-330.
54. Riedel-Kruse I.H., Müller C., Oates A.C. Synchrony dynamics during initiation, failure, and rescue of the segmentation clock. Science 2007, 317:1911-1915.
55. Ross S.E., Greenberg M.E., Stiles C.D. Basic helix-loop-helix factors in cortical development. Neuron 2003, 39:13-25.
56. Sasai Y., Kageyama R., Tagawa Y., Shigemoto R., Nakanishi S. Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev. 1992, 6:2620-2634.
57. Schroeder T., Fraser S.T., Ogawa M., Nishikawa S., Oka C., Bornkamm G.W., Nishikawa S.-I., Honjo T., Just U. Recombination signal sequence-binding protein Jk alters mesodermal cell fate decisions by suppressing cardiomyogenesis. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:4018-4023.
58. Serth K., Schuster-Gossler K., Cordes R., Gossler A. Transcriptional oscillation of Lunatic fringe is essential for somitogenesis. Genes Dev. 2003, 17:912-925.
59. Shimojo H., Ohtsuka T., Kageyama R. Oscillations in notch signaling regulate maintenance of neural progenitors. Neuron 2008, 58:52-64.
60. Taelman V., Van Wayenbergh R., Solter M., Pichon B., Pieler T., Christophe D., Bellefroid E.J. Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners. Dev. Biol. 2004, 276:47-63.
61. Takebayashi K., Sasai Y., Sakai Y., Watanabe T., Nakanishi S., Kageyama R. Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1: negative autoregulation through the multiple N box elements. J. Biol. Chem. 1994, 269:5150-5156.
62. Tomita K., Ishibashi M., Nakahara K., Ang S.-L., Nakanishi S., Guillemot F., Kageyama R. Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis. Neuron 1996, 16:723-734.
63. Yoshiura S., Ohtsuka T., Takenaka Y., Nagahara H., Yoshikawa K., Kageyama R. Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:11292-11297.
64. Zhang N., Gridley T. Defects in somite formation in lunatic fringe-deficient mice. Nature 1998, 394:374-377.