SCOPUS 정보 검색 플랫폼

Volumn 21, Issue 15, 2013, Pages 4581-4590

Synthesis of novel celecoxib analogues by bioisosteric replacement of sulfonamide as potent anti-inflammatory agents and cyclooxygenase inhibitors

(9) Chandna, Nisha a,b Kumar, Satish a Kaushik, Pawan a Kaushik, Dhirender a Roy, Somendu K c Gupta, Girish K d Jachak, Sanjay M c Kapoor, Jitander K b Sharma, Pawan K a

a KURUKSHETRA UNIVERSITY (India)

b NATIONAL INSTITUTE OF TECHNOLOGY (India)

c NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER (India)

d MAHARISHI MARKANDESHWAR DEEMED TO BE UNIVERSITY (India)

Author keywords

1,5 Diarylpyrazoles; Anti inflammatory activity; Bioisostere; Carbothioamide; Cyclooxygenase inhibitors; Inflammation; NSAIDs; Sulfonamide

Indexed keywords

4 [5 (4 BROMOPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENECARBOTHIOAMIDE; 4 [5 (4 BROMOPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZONITRILE; 4 [5 (4 CHLOROPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENECARBOTHIOAMIDE; 4 [5 (4 CHLOROPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZONITRILE; 4 [5 (4 FLUOROPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENECARBOTHIOAMIDE; 4 [5 (4 FLUOROPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZONITRILE; 4 [5 (4 METHOXYPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENECARBOTHIOAMIDE; 4 [5 (4 METHOXYPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZONITRILE; 4 [5 (4 METHYLPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENECARBOTHIOAMIDE; 4 [5 (4 METHYLPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZONITRILE; 4 [5 (FURAN 2 YL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENECARBOTHIOAMIDE; 4 [5 (FURAN 2 YL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZONITRILE; 4 [5 (NAPHTHALEN 2 YL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENECARBOTHIOAMIDE; 4 [5 (NAPHTHALEN 2 YL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZONITRILE; 4 [5 (THIOPHEN 2 YL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENECARBOTHIOAMIDE; 4 [5 (THIOPHEN 2 YL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZONITRILE; 4 [5 PHENYL 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENECARBOTHIOAMIDE; 4 [5 PHENYL 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZONITRILE; ANTIINFLAMMATORY AGENT; CARRAGEENAN; CELECOXIB; CELECOXIB DERIVATIVE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; INDOMETACIN; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOISOSTERE; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ASSAY; ENZYME INHIBITION; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR DOCKING; NONHUMAN; PAW EDEMA; RAT; TREATMENT OUTCOME;

RATTUS;

EID: 84879688131 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.05.029 Document Type: Article

Times cited : (69)

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