A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 3, 2011, Pages 1172-1178

  Joseph, Pascale ^a   Ouahrani Bettache, Safia ^a   Montero, Jean Louis ^b   Nishimori, Isao ^c   Minakuchi, Tomoko ^c   Vullo, Daniela ^d   Scozzafava, Andrea ^d   Winum, Jean Yves ^b   Köhler, Stephan ^a   Supuran, Claudiu T ^d  

^a University of Montpellier I and II   (France)

^b INSTITUT CHARLES GERHARDT   (France)

^c KOCHI MEDICAL SCHOOL   (Japan)

^d UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Class enzyme; Antibacterials; Brucella suis; Carbonic anhydrase; Sulfamate; Sulfonamide

Indexed keywords

ALIPHATIC CARBOXYLIC ACID; BETA CARBONIC ANHYDRASE; BICARBONATE; CARBON DIOXIDE; CARBONATE DEHYDRATASE; SULFAMIC ACID; SULFONAMIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM CULTURE; BRUCELLA SUIS; CATALYSIS; CLONING; CONTROLLED STUDY; ENZYME INHIBITION; GLYCOSYLATION; HYDRATION; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE;

ANTI-BACTERIAL AGENTS; BRUCELLA SUIS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CLONING, MOLECULAR; DRUG DESIGN; DRUG DISCOVERY; INHIBITORY CONCENTRATION 50; KINETICS; SULFONAMIDES; SULFONIC ACIDS;

BACTERIA (MICROORGANISMS); BRUCELLA MELITENSIS BIOVAR SUIS;

EID: 79551502223     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.12.048     Document Type: Article

References (34)

1. D.J. Payne, M.N. Gwynn, D.J. Holmes, and D.L. Pompliano Nat. Rev. Drug Disc. 6 2007 29
2. M.A. Fischbach, and C.T. Walsh Science 325 2009 1089
3. G. Devasahayam, W.M. Scheld, and P.S. Hoffman Expert Opin. Invest. Drugs 19 2010 215
4. C.T. Supuran, and J.-Y. Winum Introduction to Zinc Enzymes as Drug Targets C.T. Supuran, J.-Y. Winum, Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications 2009 Wiley Hoboken 3 12
5. J.-Y. Winum, S. Köhler, A. Scozzafava, J.-L. Montero, and C.T. Supuran Anti-Infect. Agents Med. Chem. 7 2008 169
6. C.T. Supuran Nat. Rev. Drug Disc. 7 2008 168
7. C.T. Supuran Bioorg. Med. Chem. Lett. 20 2010 3467
8. I. Nishimori, S. Onishi, H. Takeuchi, and C.T. Supuran Curr. Pharm. Des. 14 2008 622
9. T. Minakuchi, I. Nishimori, D. Vullo, A. Scozzafava, and C.T. Supuran J. Med. Chem. 52 2009 2226
10. I. Nishimori, T. Minakuchi, D. Vullo, A. Scozzafava, A. Innocenti, and C.T. Supuran J. Med. Chem. 52 2009 3116
11. F. Carta, A. Maresca, A. Suarez Covarrubias, S.L. Mowbray, T.A. Jones, and C.T. Supuran Bioorg. Med. Chem. Lett. 19 2009 6649
12. I. Nishimori, T. Minakuchi, T. Kohsaki, S. Onishi, H. Takeuchi, D. Vullo, A. Scozzafava, and C.T. Supuran Bioorg. Med. Chem. Lett. 17 2007 3585
13. K.S. Smith, C. Jakubzick, T.S. Whittam, and J.G. Ferry Proc. Natl. Acad. Sci. U.S.A. 96 1999 15184
14. R.S. Rowlett Biochim. Biophys. Acta 1804 2010 362
15. V.G. DelVecchio, V. Kapatral, R.J. Redkar, G. Patra, C. Mujer, T. Los, N. Ivanova, I. Anderson, A. Bhattacharyya, A. Lykidis, G. Reznik, L. Jablonski, N. Larsen, M. D'Souza, A. Bernal, M. Mazur, E. Goltsman, E. Selkov, P.H. Elzer, S. Hagius, D. O'Callaghan, J.J. Letesson, R. Haselkorn, N. Kyrpides, and R. Overbeek Proc. Natl. Acad. Sci. U.S.A. 99 2002 443
16. I.T. Paulsen, R. Seshadri, K.E. Nelson, J.A. Eisen, J.F. Heidelberg, T.D. Read, R.J. Dodson, L. Umayam, L.M. Brinkac, M.J. Beanan, S.C. Daugherty, R.T. Deboy, A.S. Durkin, J.F. Kolonay, R. Madupu, W.C. Nelson, B. Ayodeji, M. Kraul, J. Shetty, J. Malek, S.E. Van Aken, S. Riedmuller, H. Tettelin, S.R. Gill, O. White, S.L. Salzberg, D.L. Hoover, L.E. Lindler, S.M. Halling, S.M. Boyle, and C.M. Fraser Proc. Natl. Acad. Sci. U.S.A. 99 2002 13148
17. S.M. Halling, B.D. Peterson-Burch, B.J. Bricker, R.L. Zuerner, Z. Qing, L.L. Li, V. Kapur, D.P. Alt, and S.C. Olsen J. Bacteriol. 187 2005 2715
18. Lopez-Goni, I.; Moriyon, I. Brucella: Molecular and cellular biology; Horizon Bioscience, 2004: pp 1-432.
19. H. Guerra Crit. Rev. Microbiol. 33 2007 325
20. M.P. Franco, M. Mulder, R.H. Gilman, and H.L. Smits Lancet Infect. Dis. 7 2007 775
21. G. Pappas, P. Papadimitriou, N. Akritidis, L. Christou, and E.V. Tsianos Lancet Infect. Dis. 6 2006 91
22. P. Joseph, F. Turtaut, S. Ouahrani-Bettache, J.-L. Montero, I. Nishimori, T. Minakuchi, D. Vullo, A. Scozzafava, S. Köhler, J.-Y. Winum, and C.T. Supuran J. Med. Chem. 53 2010 2277
23. D. Vullo, I. Nishimori, A. Scozzafava, S. Köhler, J.-Y. Winum, and C.T. Supuran Bioorg. Med. Chem. Lett. 20 2010 2178
24. A. Suarez Covarrubias, A.M. Larsson, M. Hogbom, J. Lindberg, T. Bergfors, C. Bjorkelid, S.L. Mowbray, T. Unge, and T.A. Jones J. Biol. Chem. 280 2005 18782
25. A. Suarez Covarrubias, T. Bergfors, T.A. Jones, and M. Hogbom J. Biol. Chem. 281 2006 4993
26. J.-Y. Winum, D. Vullo, A. Casini, J.-L. Montero, A. Scozzafava, and C.T. Supuran J. Med. Chem. 46 2003 2197
27. J.-Y. Winum, S. Pastorekova, L. Jakubickova, J.-L. Montero, A. Scozzafava, J. Pastorek, D. Vullo, A. Innocenti, and C.T. Supuran Bioorg. Med. Chem. Lett. 15 2005 579
28. J.-Y. Winum, A. Casini, F. Mincione, M. Starnotti, J.-L. Montero, A. Scozzafava, and C.T. Supuran Bioorg. Med. Chem. Lett. 14 2004 225
29. A. Scozzafava, F. Briganti, M.A. Ilies, and C.T. Supuran J. Med. Chem. 43 2000 292
30. A. Scozzafava, L. Menabuoni, F. Mincione, F. Briganti, G. Mincione, and C.T. Supuran J. Med. Chem. 42 1999 2641
31. A. Scozzafava, L. Menabuoni, F. Mincione, F. Briganti, G. Mincione, and C.T. Supuran J. Med. Chem. 43 2000 4542
32. A. Scozzafava, L. Menabuoni, F. Mincione, and C.T. Supuran J. Med. Chem. 45 2002 1466
33. R.G. Khalifah J. Biol. Chem. 246 1971 2561
34. M. Dozot, R.A. Boigegrain, R.M. Delrue, R. Hallez, S. Ouahrani-Bettache, I. Danese, J.-J. Letesson, X. De Bolle, and S. Köhler Cell Microbiol. 8 2006 1791